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Network neighborhood for query Sequence : UBR2_HUMAN

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UBR2_HUMAN
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBR1_HUMAN
θ value	0 (rank : 1)	NC score	0.979819 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR1_MOUSE
θ value	0 (rank : 2)	NC score	0.978723 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR2_MOUSE
θ value	0 (rank : 4)	NC score	0.997524 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

RAI14_MOUSE
θ value	0.163984 (rank : 5)	NC score	0.011436 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	1505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

STMN2_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.040957 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	458	Shared Neighborhood Hits	9
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	0.47712 (rank : 7)	NC score	0.040957 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	458	Shared Neighborhood Hits	9
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

SYAC_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.031667 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

KR10A_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.017413 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	232	Shared Neighborhood Hits	3
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

SYAC_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.029785 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

ULK4_MOUSE
θ value	1.38821 (rank : 11)	NC score	0.004538 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	793	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

ARNT_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.024034 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.023596 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

DCAK1_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.002356 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	877	Shared Neighborhood Hits	4
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

CHD6_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.009174 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

LRTM4_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.005307 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	284	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XG9, Q8C030, Q8JZS8	Gene names	Lrrtm4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

BCL6_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.002329 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	913	Shared Neighborhood Hits	5
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

CAND2_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.022506 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

TRI17_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.005190 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	318	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

ITPR2_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.008481 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

UBP38_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.022569 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

ABTB2_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.011091 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	391	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.011237 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

FMO2_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.007041 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

GOGA4_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.004607 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	1939	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

TDRD7_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.012345 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1H1, Q8R181	Gene names	Tdrd7, Pctaire2bp
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

UBP38_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.017337 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

BCL6_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.002136 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	922	Shared Neighborhood Hits	5
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

CASP_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.005881 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	1152	Shared Neighborhood Hits	12
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.005549 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	1620	Shared Neighborhood Hits	14
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ITB1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.004139 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	283	Shared Neighborhood Hits	2
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KIF14_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.004454 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	732	Shared Neighborhood Hits	10
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

LMNB1_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.004623 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	719	Shared Neighborhood Hits	8
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

TLE4_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.005874 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	477	Shared Neighborhood Hits	5
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.005864 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	482	Shared Neighborhood Hits	5
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TRPV3_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.013749 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

DCAK1_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.001210 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

EDD1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.025290 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.025312 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

LMNB1_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.004079 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	714	Shared Neighborhood Hits	8
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

RNF25_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.019149 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RNF25_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.019606 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RRBP1_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.003690 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	1650	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SMCA2_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.005743 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	503	Shared Neighborhood Hits	9
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

TRPV3_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.012443 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

UBR2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR2_MOUSE
NC score	0.997524 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR1_HUMAN
NC score	0.979819 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR1_MOUSE
NC score	0.978723 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

STMN2_HUMAN
NC score	0.040957 (rank : 5)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	458	Shared Neighborhood Hits	9
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.040957 (rank : 6)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	458	Shared Neighborhood Hits	9
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

SYAC_HUMAN
NC score	0.031667 (rank : 7)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

SYAC_MOUSE
NC score	0.029785 (rank : 8)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

EDD1_MOUSE
NC score	0.025312 (rank : 9)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.025290 (rank : 10)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

ARNT_HUMAN
NC score	0.024034 (rank : 11)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
NC score	0.023596 (rank : 12)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	213	Shared Neighborhood Hits	4
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

UBP38_HUMAN
NC score	0.022569 (rank : 13)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

CAND2_MOUSE
NC score	0.022506 (rank : 14)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

RNF25_MOUSE
NC score	0.019606 (rank : 15)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RNF25_HUMAN
NC score	0.019149 (rank : 16)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

KR10A_HUMAN
NC score	0.017413 (rank : 17)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	232	Shared Neighborhood Hits	3
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

UBP38_MOUSE
NC score	0.017337 (rank : 18)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

TRPV3_MOUSE
NC score	0.013749 (rank : 19)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.012443 (rank : 20)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TDRD7_MOUSE
NC score	0.012345 (rank : 21)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1H1, Q8R181	Gene names	Tdrd7, Pctaire2bp
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

RAI14_MOUSE
NC score	0.011436 (rank : 22)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	1505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ABTB2_MOUSE
NC score	0.011237 (rank : 23)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_HUMAN
NC score	0.011091 (rank : 24)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	391	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CHD6_HUMAN
NC score	0.009174 (rank : 25)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

ITPR2_HUMAN
NC score	0.008481 (rank : 26)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

FMO2_MOUSE
NC score	0.007041 (rank : 27)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2I3, Q9QZF7	Gene names	Fmo2
Domain Architecture	No domain graphic available
Description	Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2).

CASP_MOUSE
NC score	0.005881 (rank : 28)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	1152	Shared Neighborhood Hits	12
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

TLE4_HUMAN
NC score	0.005874 (rank : 29)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	477	Shared Neighborhood Hits	5
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
NC score	0.005864 (rank : 30)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	482	Shared Neighborhood Hits	5
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

SMCA2_HUMAN
NC score	0.005743 (rank : 31)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	503	Shared Neighborhood Hits	9
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

CUTL1_MOUSE
NC score	0.005549 (rank : 32)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	1620	Shared Neighborhood Hits	14
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

LRTM4_MOUSE
NC score	0.005307 (rank : 33)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	284	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XG9, Q8C030, Q8JZS8	Gene names	Lrrtm4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 4 precursor.

TRI17_HUMAN
NC score	0.005190 (rank : 34)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	318	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

LMNB1_MOUSE
NC score	0.004623 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	719	Shared Neighborhood Hits	8
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

GOGA4_MOUSE
NC score	0.004607 (rank : 36)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	1939	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

ULK4_MOUSE
NC score	0.004538 (rank : 37)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	793	Shared Neighborhood Hits	4
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

KIF14_HUMAN
NC score	0.004454 (rank : 38)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	732	Shared Neighborhood Hits	10
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

ITB1_MOUSE
NC score	0.004139 (rank : 39)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	283	Shared Neighborhood Hits	2
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LMNB1_HUMAN
NC score	0.004079 (rank : 40)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	714	Shared Neighborhood Hits	8
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

RRBP1_MOUSE
NC score	0.003690 (rank : 41)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	1650	Shared Neighborhood Hits	12
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

DCAK1_HUMAN
NC score	0.002356 (rank : 42)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	877	Shared Neighborhood Hits	4
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

BCL6_MOUSE
NC score	0.002329 (rank : 43)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	913	Shared Neighborhood Hits	5
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BCL6_HUMAN
NC score	0.002136 (rank : 44)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	922	Shared Neighborhood Hits	5
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

DCAK1_MOUSE
NC score	0.001210 (rank : 45)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLM8, Q6P207	Gene names	Dcamkl1, Dclk
Domain Architecture
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).