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Network neighborhood for query Sequence : SYAC_HUMAN

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SYAC_HUMAN
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYAC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

SYAC_MOUSE
θ value	0 (rank : 2)	NC score	0.993737 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

SYAM_HUMAN
θ value	0 (rank : 3)	NC score	0.966895 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JTZ9, Q8N198, Q96D02, Q9ULF0	Gene names	AARSL, AARS2, KIAA1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

SYAM_MOUSE
θ value	0 (rank : 4)	NC score	0.962015 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q14CH7, Q68FH3, Q69ZM9	Gene names	Aarsl, Aars2, Kiaa1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

MYH9_HUMAN
θ value	0.0193708 (rank : 5)	NC score	0.051485 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	1762	Shared Neighborhood Hits	36
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH11_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.050966 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	1806	Shared Neighborhood Hits	39
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.0961366 (rank : 7)	NC score	0.049507 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	1777	Shared Neighborhood Hits	39
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.049357 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	1829	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GRP78_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.035588 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.035478 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	216	Shared Neighborhood Hits	20
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

CK5P2_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.038508 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	1433	Shared Neighborhood Hits	34
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MACF1_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.044927 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	1341	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.050057 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	1321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CUTL2_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.042163 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	771	Shared Neighborhood Hits	28
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

RAI14_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.031204 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	1505	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

UBR2_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.031667 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

LRC45_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.041024 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	933	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CP135_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.034797 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	1290	Shared Neighborhood Hits	34
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH7_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.044906 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	1559	Shared Neighborhood Hits	37
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH1_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.043454 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	1478	Shared Neighborhood Hits	37
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

TRIPB_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.037385 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	1587	Shared Neighborhood Hits	35
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GOGA4_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.033071 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	1939	Shared Neighborhood Hits	36
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MACF1_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.038202 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	1313	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

VINC_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.046942 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

CYLN2_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.037924 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	1004	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

ITPR3_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.010320 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

MYH13_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.042822 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	1504	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH4_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.044107 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	1476	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

TTC3_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.028737 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	664	Shared Neighborhood Hits	27
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

AIRE_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.016291 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

CCAR1_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.028940 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	414	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CEP63_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.033823 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	1005	Shared Neighborhood Hits	33
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CK5P2_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.038294 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	1151	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

MYH1_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.042292 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	1461	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

RBBP6_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.011375 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	1014	Shared Neighborhood Hits	13
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SMC1A_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.031134 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	1346	Shared Neighborhood Hits	34
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.031268 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	1384	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

CYLN2_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.035728 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	1002	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

PGCA_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.008127 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	821	Shared Neighborhood Hits	5
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SEM3C_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.006514 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

VINC_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.046942 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	145	Shared Neighborhood Hits	22
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

MYH8_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.041933 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	1610	Shared Neighborhood Hits	38
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NUMA1_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.033695 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	1523	Shared Neighborhood Hits	36
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

OSBP2_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.005394 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

PLEC1_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.029995 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	1326	Shared Neighborhood Hits	31
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

UTRO_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.034513 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	960	Shared Neighborhood Hits	30
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

Hits sorted by NC score

SYAC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	P49588, Q53GV7, Q96FA0	Gene names	AARS
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (NY-REN-42 antigen).

SYAC_MOUSE
NC score	0.993737 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

SYAM_HUMAN
NC score	0.966895 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JTZ9, Q8N198, Q96D02, Q9ULF0	Gene names	AARSL, AARS2, KIAA1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

SYAM_MOUSE
NC score	0.962015 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q14CH7, Q68FH3, Q69ZM9	Gene names	Aarsl, Aars2, Kiaa1270
Domain Architecture	No domain graphic available
Description	Probable alanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS) (Alanyl-tRNA synthetase like).

MYH9_HUMAN
NC score	0.051485 (rank : 5)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	1762	Shared Neighborhood Hits	36
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH11_HUMAN
NC score	0.050966 (rank : 6)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	1806	Shared Neighborhood Hits	39
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MACF4_HUMAN
NC score	0.050057 (rank : 7)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	1321	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYH11_MOUSE
NC score	0.049507 (rank : 8)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	1777	Shared Neighborhood Hits	39
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
NC score	0.049357 (rank : 9)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	1829	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

VINC_MOUSE
NC score	0.046942 (rank : 10)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_HUMAN
NC score	0.046942 (rank : 11)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	145	Shared Neighborhood Hits	22
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

MACF1_HUMAN
NC score	0.044927 (rank : 12)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	1341	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MYH7_HUMAN
NC score	0.044906 (rank : 13)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	1559	Shared Neighborhood Hits	37
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH4_MOUSE
NC score	0.044107 (rank : 14)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	1476	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH1_HUMAN
NC score	0.043454 (rank : 15)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	1478	Shared Neighborhood Hits	37
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH13_HUMAN
NC score	0.042822 (rank : 16)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	1504	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_MOUSE
NC score	0.042292 (rank : 17)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	1461	Shared Neighborhood Hits	37
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

CUTL2_MOUSE
NC score	0.042163 (rank : 18)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	771	Shared Neighborhood Hits	28
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MYH8_HUMAN
NC score	0.041933 (rank : 19)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	1610	Shared Neighborhood Hits	38
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

LRC45_HUMAN
NC score	0.041024 (rank : 20)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	933	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CK5P2_HUMAN
NC score	0.038508 (rank : 21)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	1433	Shared Neighborhood Hits	34
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
NC score	0.038294 (rank : 22)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	1151	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

MACF1_MOUSE
NC score	0.038202 (rank : 23)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	1313	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

CYLN2_HUMAN
NC score	0.037924 (rank : 24)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	1004	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

TRIPB_HUMAN
NC score	0.037385 (rank : 25)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	1587	Shared Neighborhood Hits	35
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CYLN2_MOUSE
NC score	0.035728 (rank : 26)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	1002	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

GRP78_HUMAN
NC score	0.035588 (rank : 27)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.035478 (rank : 28)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	216	Shared Neighborhood Hits	20
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

CP135_HUMAN
NC score	0.034797 (rank : 29)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	1290	Shared Neighborhood Hits	34
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

UTRO_HUMAN
NC score	0.034513 (rank : 30)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	960	Shared Neighborhood Hits	30
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

CEP63_HUMAN
NC score	0.033823 (rank : 31)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	1005	Shared Neighborhood Hits	33
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

NUMA1_HUMAN
NC score	0.033695 (rank : 32)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	1523	Shared Neighborhood Hits	36
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

GOGA4_MOUSE
NC score	0.033071 (rank : 33)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	1939	Shared Neighborhood Hits	36
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

UBR2_HUMAN
NC score	0.031667 (rank : 34)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

SMC1A_MOUSE
NC score	0.031268 (rank : 35)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	1384	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

RAI14_MOUSE
NC score	0.031204 (rank : 36)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	1505	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SMC1A_HUMAN
NC score	0.031134 (rank : 37)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	1346	Shared Neighborhood Hits	34
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

PLEC1_HUMAN
NC score	0.029995 (rank : 38)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	1326	Shared Neighborhood Hits	31
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CCAR1_MOUSE
NC score	0.028940 (rank : 39)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	414	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

TTC3_HUMAN
NC score	0.028737 (rank : 40)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	664	Shared Neighborhood Hits	27
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

AIRE_HUMAN
NC score	0.016291 (rank : 41)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

RBBP6_MOUSE
NC score	0.011375 (rank : 42)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	1014	Shared Neighborhood Hits	13
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ITPR3_MOUSE
NC score	0.010320 (rank : 43)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

PGCA_HUMAN
NC score	0.008127 (rank : 44)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	821	Shared Neighborhood Hits	5
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SEM3C_MOUSE
NC score	0.006514 (rank : 45)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

OSBP2_HUMAN
NC score	0.005394 (rank : 46)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).