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Network neighborhood for query Sequence : COPG2_MOUSE

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COPG2_MOUSE
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COPG2_HUMAN
θ value	0 (rank : 1)	NC score	0.999445 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG_HUMAN
θ value	0 (rank : 3)	NC score	0.993190 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

AP4B1_MOUSE
θ value	2.69671e-12 (rank : 4)	NC score	0.444515 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV76	Gene names	Ap4b1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta-1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

AP1B1_HUMAN
θ value	6.64225e-11 (rank : 5)	NC score	0.416543 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP1B1_MOUSE
θ value	6.64225e-11 (rank : 6)	NC score	0.415731 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP2B1_HUMAN
θ value	1.133e-10 (rank : 7)	NC score	0.412281 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_MOUSE
θ value	1.133e-10 (rank : 8)	NC score	0.412292 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP4B1_HUMAN
θ value	1.53129e-07 (rank : 9)	NC score	0.390242 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6B7	Gene names	AP4B1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta 1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

AP1G1_HUMAN
θ value	1.87187e-05 (rank : 10)	NC score	0.254828 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
θ value	1.87187e-05 (rank : 11)	NC score	0.255492 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP3B1_MOUSE
θ value	0.00228821 (rank : 12)	NC score	0.256631 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3B1_HUMAN
θ value	0.0148317 (rank : 13)	NC score	0.248861 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	283	Shared Neighborhood Hits	20
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3D1_HUMAN
θ value	0.0148317 (rank : 14)	NC score	0.224787 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	254	Shared Neighborhood Hits	21
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

COPB_HUMAN
θ value	0.0431538 (rank : 15)	NC score	0.231935 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P53618, Q6GTT7, Q9NTK2, Q9UNW7	Gene names	COPB1, COPB
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

AP3D1_MOUSE
θ value	0.0563607 (rank : 16)	NC score	0.233638 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP4E1_MOUSE
θ value	0.0563607 (rank : 17)	NC score	0.188016 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

COPB_MOUSE
θ value	0.0563607 (rank : 18)	NC score	0.230511 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIF7	Gene names	Copb1, Copb
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

AP4E1_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.186652 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP1G2_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.181435 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.179627 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

TPSN_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.031493 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R233, O70317, Q91YE0, Q91YE1, Q9QWT7, Q9Z1W3	Gene names	Tapbp, Tapa
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein).

DGLA_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.019525 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

IF4G2_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.025863 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

CAND2_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.027134 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CAND2_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.026438 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

IF4G2_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.023820 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

CASPA_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.017836 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7	Gene names	CASP10, MCH4
Domain Architecture
Description	Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12].

FYB_HUMAN
θ value	8.99809 (rank : 29)	NC score	0.008589 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	379	Shared Neighborhood Hits	2
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

LDB3_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.005166 (rank : 37)
Query Neighborhood Hits	32	Target Neighborhood Hits	510	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PLXB1_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.003952 (rank : 38)
Query Neighborhood Hits	32	Target Neighborhood Hits	259	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

POPD2_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.009171 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBU9, Q86UE7	Gene names	POPDC2, POP2
Domain Architecture
Description	Popeye domain-containing protein 2 (Popeye protein 2).

AP2A1_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.124713 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.122486 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.133282 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.133078 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP3B2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.204138 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP3B2_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.204925 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

Hits sorted by NC score

COPG2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG2_HUMAN
NC score	0.999445 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG_HUMAN
NC score	0.993190 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

AP4B1_MOUSE
NC score	0.444515 (rank : 4)	θ value	2.69671e-12 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV76	Gene names	Ap4b1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta-1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

AP1B1_HUMAN
NC score	0.416543 (rank : 5)	θ value	6.64225e-11 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP1B1_MOUSE
NC score	0.415731 (rank : 6)	θ value	6.64225e-11 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP2B1_MOUSE
NC score	0.412292 (rank : 7)	θ value	1.133e-10 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_HUMAN
NC score	0.412281 (rank : 8)	θ value	1.133e-10 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP4B1_HUMAN
NC score	0.390242 (rank : 9)	θ value	1.53129e-07 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6B7	Gene names	AP4B1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta 1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

AP3B1_MOUSE
NC score	0.256631 (rank : 10)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP1G1_MOUSE
NC score	0.255492 (rank : 11)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_HUMAN
NC score	0.254828 (rank : 12)	θ value	1.87187e-05 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	65	Shared Neighborhood Hits	21
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP3B1_HUMAN
NC score	0.248861 (rank : 13)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	283	Shared Neighborhood Hits	20
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3D1_MOUSE
NC score	0.233638 (rank : 14)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

COPB_HUMAN
NC score	0.231935 (rank : 15)	θ value	0.0431538 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P53618, Q6GTT7, Q9NTK2, Q9UNW7	Gene names	COPB1, COPB
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

COPB_MOUSE
NC score	0.230511 (rank : 16)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIF7	Gene names	Copb1, Copb
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

AP3D1_HUMAN
NC score	0.224787 (rank : 17)	θ value	0.0148317 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	254	Shared Neighborhood Hits	21
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3B2_MOUSE
NC score	0.204925 (rank : 18)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	32	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

AP3B2_HUMAN
NC score	0.204138 (rank : 19)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	32	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP4E1_MOUSE
NC score	0.188016 (rank : 20)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP4E1_HUMAN
NC score	0.186652 (rank : 21)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP1G2_HUMAN
NC score	0.181435 (rank : 22)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_MOUSE
NC score	0.179627 (rank : 23)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP2A2_HUMAN
NC score	0.133282 (rank : 24)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
NC score	0.133078 (rank : 25)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A1_HUMAN
NC score	0.124713 (rank : 26)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_MOUSE
NC score	0.122486 (rank : 27)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

TPSN_MOUSE
NC score	0.031493 (rank : 28)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R233, O70317, Q91YE0, Q91YE1, Q9QWT7, Q9Z1W3	Gene names	Tapbp, Tapa
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein).

CAND2_HUMAN
NC score	0.027134 (rank : 29)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CAND2_MOUSE
NC score	0.026438 (rank : 30)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

IF4G2_MOUSE
NC score	0.025863 (rank : 31)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

IF4G2_HUMAN
NC score	0.023820 (rank : 32)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

DGLA_MOUSE
NC score	0.019525 (rank : 33)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

CASPA_HUMAN
NC score	0.017836 (rank : 34)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7	Gene names	CASP10, MCH4
Domain Architecture
Description	Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12].

POPD2_HUMAN
NC score	0.009171 (rank : 35)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBU9, Q86UE7	Gene names	POPDC2, POP2
Domain Architecture
Description	Popeye domain-containing protein 2 (Popeye protein 2).

FYB_HUMAN
NC score	0.008589 (rank : 36)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	379	Shared Neighborhood Hits	2
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

LDB3_MOUSE
NC score	0.005166 (rank : 37)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	510	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PLXB1_MOUSE
NC score	0.003952 (rank : 38)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	259	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.