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Network neighborhood for query Sequence : IMA4_MOUSE

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IMA4_MOUSE
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMA3_HUMAN
θ value	0 (rank : 1)	NC score	0.996484 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	53	Shared Neighborhood Hits	43
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	0 (rank : 2)	NC score	0.996410 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	56	Shared Neighborhood Hits	43
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA4_HUMAN
θ value	0 (rank : 3)	NC score	0.999827 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA2_MOUSE
θ value	1.47209e-143 (rank : 5)	NC score	0.977093 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
θ value	3.62588e-142 (rank : 6)	NC score	0.975346 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA5_HUMAN
θ value	5.43074e-130 (rank : 7)	NC score	0.970373 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_MOUSE
θ value	1.33764e-128 (rank : 8)	NC score	0.972265 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA7_HUMAN
θ value	1.74701e-128 (rank : 9)	NC score	0.973148 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA1_MOUSE
θ value	1.69212e-123 (rank : 10)	NC score	0.971320 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA1_HUMAN
θ value	2.20997e-123 (rank : 11)	NC score	0.971792 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

SPAG6_MOUSE
θ value	1.29331e-14 (rank : 12)	NC score	0.635506 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

SPAG6_HUMAN
θ value	2.88119e-14 (rank : 13)	NC score	0.634731 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

PKP4_HUMAN
θ value	0.00509761 (rank : 14)	NC score	0.161978 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
θ value	0.00509761 (rank : 15)	NC score	0.162253 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

TRIPC_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.114031 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	319	Shared Neighborhood Hits	11
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

CTNB1_HUMAN
θ value	0.0113563 (rank : 17)	NC score	0.157389 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	0.0113563 (rank : 18)	NC score	0.157433 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

TNPO2_HUMAN
θ value	0.0252991 (rank : 19)	NC score	0.106366 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	0.0252991 (rank : 20)	NC score	0.107614 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

ARVC_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.116274 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	95	Shared Neighborhood Hits	28
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

SARM1_MOUSE
θ value	0.0330416 (rank : 22)	NC score	0.112392 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

ARVC_MOUSE
θ value	0.0431538 (rank : 23)	NC score	0.114757 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

SARM1_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.112067 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

GCN1L_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.084320 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

REST_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.012423 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	1605	Shared Neighborhood Hits	12
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TNPO1_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.120712 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	64	Shared Neighborhood Hits	16
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.115784 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

GDS1_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.265697 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

ARMX1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.054952 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

CTND1_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.119142 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

IMB3_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.050359 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.050466 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

CTND1_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.111381 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

SIL1_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.049541 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H173, Q8N2L3	Gene names	SIL1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP).

ZC3H6_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.021604 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CTND2_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.123697 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	333	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND2_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.124678 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

IMB1_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.100625 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

KTN1_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.013746 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	1324	Shared Neighborhood Hits	12
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PHTF1_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.024290 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ09, Q9CS51, Q9CSB9, Q9QZ14	Gene names	Phtf1, Phtf
Domain Architecture	No domain graphic available
Description	Putative homeodomain transcription factor 1.

UN45A_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.054813 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	122	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

ARMX1_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.045071 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

UN45A_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.046937 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

ARMC4_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.233555 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

UBP42_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.007985 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	445	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

ARMX2_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.031433 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ARMX2_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.028948 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

KTN1_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.012257 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	1197	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

REST_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.007043 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	1506	Shared Neighborhood Hits	11
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RIF1_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.014865 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	315	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

K2C1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.003075 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	624	Shared Neighborhood Hits	8
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

CALD1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.004922 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	959	Shared Neighborhood Hits	9
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

DHX16_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.004961 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	356	Shared Neighborhood Hits	7
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

PKP1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.061203 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

MMS19_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.012609 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D071, Q925N8, Q9CWX3	Gene names	Mms19l, Mms19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (MET18 homolog).

NF2L2_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.006812 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PTN7_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.005367 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

TTMP_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.009200 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5C9, Q91YJ8	Gene names
Domain Architecture	No domain graphic available
Description	TPA-induced transmembrane protein homolog.

ZC3H6_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.012296 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

IMB1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.079305 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

PKP1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.056968 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP3_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.054851 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.052278 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PLAK_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.101336 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.133167 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

RL35_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.085039 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P42766, Q4VBY5, Q5JTN5, Q6IBC7, Q96QJ7, Q9BYF4	Gene names	RPL35
Domain Architecture	No domain graphic available
Description	60S ribosomal protein L35.

Hits sorted by NC score

IMA4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.999827 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA3_HUMAN
NC score	0.996484 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	53	Shared Neighborhood Hits	43
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
NC score	0.996410 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	56	Shared Neighborhood Hits	43
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA2_MOUSE
NC score	0.977093 (rank : 5)	θ value	1.47209e-143 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
NC score	0.975346 (rank : 6)	θ value	3.62588e-142 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA7_HUMAN
NC score	0.973148 (rank : 7)	θ value	1.74701e-128 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
NC score	0.972265 (rank : 8)	θ value	1.33764e-128 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA1_HUMAN
NC score	0.971792 (rank : 9)	θ value	2.20997e-123 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.971320 (rank : 10)	θ value	1.69212e-123 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA5_HUMAN
NC score	0.970373 (rank : 11)	θ value	5.43074e-130 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

SPAG6_MOUSE
NC score	0.635506 (rank : 12)	θ value	1.29331e-14 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

SPAG6_HUMAN
NC score	0.634731 (rank : 13)	θ value	2.88119e-14 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

GDS1_HUMAN
NC score	0.265697 (rank : 14)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

ARMC4_HUMAN
NC score	0.233555 (rank : 15)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

PKP4_MOUSE
NC score	0.162253 (rank : 16)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
NC score	0.161978 (rank : 17)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTNB1_MOUSE
NC score	0.157433 (rank : 18)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.157389 (rank : 19)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.133167 (rank : 20)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

CTND2_MOUSE
NC score	0.124678 (rank : 21)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.123697 (rank : 22)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	333	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

TNPO1_HUMAN
NC score	0.120712 (rank : 23)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	64	Shared Neighborhood Hits	16
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

CTND1_MOUSE
NC score	0.119142 (rank : 24)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

ARVC_HUMAN
NC score	0.116274 (rank : 25)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	95	Shared Neighborhood Hits	28
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

TNPO1_MOUSE
NC score	0.115784 (rank : 26)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	63	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

ARVC_MOUSE
NC score	0.114757 (rank : 27)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

TRIPC_HUMAN
NC score	0.114031 (rank : 28)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	319	Shared Neighborhood Hits	11
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

SARM1_MOUSE
NC score	0.112392 (rank : 29)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SARM1_HUMAN
NC score	0.112067 (rank : 30)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

CTND1_HUMAN
NC score	0.111381 (rank : 31)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

TNPO2_MOUSE
NC score	0.107614 (rank : 32)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.106366 (rank : 33)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

PLAK_HUMAN
NC score	0.101336 (rank : 34)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

IMB1_MOUSE
NC score	0.100625 (rank : 35)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

RL35_HUMAN
NC score	0.085039 (rank : 36)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P42766, Q4VBY5, Q5JTN5, Q6IBC7, Q96QJ7, Q9BYF4	Gene names	RPL35
Domain Architecture	No domain graphic available
Description	60S ribosomal protein L35.

GCN1L_HUMAN
NC score	0.084320 (rank : 37)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMB1_HUMAN
NC score	0.079305 (rank : 38)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

PKP1_HUMAN
NC score	0.061203 (rank : 39)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
NC score	0.056968 (rank : 40)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

ARMX1_HUMAN
NC score	0.054952 (rank : 41)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

PKP3_HUMAN
NC score	0.054851 (rank : 42)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

UN45A_HUMAN
NC score	0.054813 (rank : 43)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	122	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

PKP3_MOUSE
NC score	0.052278 (rank : 44)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

IMB3_MOUSE
NC score	0.050466 (rank : 45)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
NC score	0.050359 (rank : 46)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	13
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

SIL1_HUMAN
NC score	0.049541 (rank : 47)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H173, Q8N2L3	Gene names	SIL1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP).

UN45A_MOUSE
NC score	0.046937 (rank : 48)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

ARMX1_MOUSE
NC score	0.045071 (rank : 49)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

ARMX2_HUMAN
NC score	0.031433 (rank : 50)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ARMX2_MOUSE
NC score	0.028948 (rank : 51)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

PHTF1_MOUSE
NC score	0.024290 (rank : 52)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ09, Q9CS51, Q9CSB9, Q9QZ14	Gene names	Phtf1, Phtf
Domain Architecture	No domain graphic available
Description	Putative homeodomain transcription factor 1.

ZC3H6_MOUSE
NC score	0.021604 (rank : 53)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	239	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

RIF1_MOUSE
NC score	0.014865 (rank : 54)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	315	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

KTN1_MOUSE
NC score	0.013746 (rank : 55)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	1324	Shared Neighborhood Hits	12
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MMS19_MOUSE
NC score	0.012609 (rank : 56)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D071, Q925N8, Q9CWX3	Gene names	Mms19l, Mms19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (MET18 homolog).

REST_HUMAN
NC score	0.012423 (rank : 57)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	1605	Shared Neighborhood Hits	12
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ZC3H6_HUMAN
NC score	0.012296 (rank : 58)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

KTN1_HUMAN
NC score	0.012257 (rank : 59)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	1197	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TTMP_MOUSE
NC score	0.009200 (rank : 60)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5C9, Q91YJ8	Gene names
Domain Architecture	No domain graphic available
Description	TPA-induced transmembrane protein homolog.

UBP42_HUMAN
NC score	0.007985 (rank : 61)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	445	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

REST_MOUSE
NC score	0.007043 (rank : 62)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	1506	Shared Neighborhood Hits	11
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

NF2L2_MOUSE
NC score	0.006812 (rank : 63)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PTN7_HUMAN
NC score	0.005367 (rank : 64)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

DHX16_HUMAN
NC score	0.004961 (rank : 65)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	356	Shared Neighborhood Hits	7
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

CALD1_HUMAN
NC score	0.004922 (rank : 66)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	959	Shared Neighborhood Hits	9
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

K2C1_HUMAN
NC score	0.003075 (rank : 67)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	624	Shared Neighborhood Hits	8
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).