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Network neighborhood for query Sequence : IMA5_HUMAN

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IMA5_HUMAN
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMA1_HUMAN
θ value	0 (rank : 1)	NC score	0.991482 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
θ value	0 (rank : 2)	NC score	0.991340 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA5_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
θ value	0 (rank : 4)	NC score	0.992762 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
θ value	0 (rank : 5)	NC score	0.991276 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA3_MOUSE
θ value	1.92707e-135 (rank : 6)	NC score	0.972133 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
θ value	3.6343e-134 (rank : 7)	NC score	0.972039 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA4_HUMAN
θ value	6.41512e-131 (rank : 8)	NC score	0.970810 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	32
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	5.43074e-130 (rank : 9)	NC score	0.970373 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA2_MOUSE
θ value	1.13238e-127 (rank : 10)	NC score	0.974478 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
θ value	3.64273e-126 (rank : 11)	NC score	0.972242 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

SPAG6_HUMAN
θ value	8.95645e-16 (rank : 12)	NC score	0.640789 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

SPAG6_MOUSE
θ value	4.44505e-15 (rank : 13)	NC score	0.637872 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

ARMC4_HUMAN
θ value	1.43324e-05 (rank : 14)	NC score	0.286632 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

GDS1_HUMAN
θ value	9.29e-05 (rank : 15)	NC score	0.306536 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

ARMX3_MOUSE
θ value	0.00228821 (rank : 16)	NC score	0.085504 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

ARMX3_HUMAN
θ value	0.00298849 (rank : 17)	NC score	0.084915 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

IMB1_HUMAN
θ value	0.00869519 (rank : 18)	NC score	0.106684 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

CTNB1_HUMAN
θ value	0.0113563 (rank : 19)	NC score	0.175562 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	0.0113563 (rank : 20)	NC score	0.175603 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTND2_HUMAN
θ value	0.0148317 (rank : 21)	NC score	0.145200 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	333	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

IMB1_MOUSE
θ value	0.0148317 (rank : 22)	NC score	0.127826 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

PKP4_HUMAN
θ value	0.0148317 (rank : 23)	NC score	0.175243 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	107	Shared Neighborhood Hits	29
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
θ value	0.0148317 (rank : 24)	NC score	0.177495 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

CTND2_MOUSE
θ value	0.0193708 (rank : 25)	NC score	0.145260 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

ARMX1_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.078134 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

TNPO1_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.099123 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	0.0563607 (rank : 28)	NC score	0.095373 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

LRRK2_MOUSE
θ value	0.0736092 (rank : 29)	NC score	0.006957 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	1359	Shared Neighborhood Hits	6
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

PLAK_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.175290 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

ARMX1_MOUSE
θ value	0.163984 (rank : 31)	NC score	0.069644 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

ARVC_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.130195 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
θ value	0.21417 (rank : 33)	NC score	0.129298 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND1_HUMAN
θ value	0.279714 (rank : 34)	NC score	0.122122 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.130756 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

UN45A_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.059043 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

ZFY16_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.036438 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

PLAK_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.138087 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

DBNL_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.017423 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

SFPQ_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.011461 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	986	Shared Neighborhood Hits	7
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

AGGF1_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.017551 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

RELN_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.046333 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

2AAA_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.022641 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

RELN_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.034327 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

TRHY_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.000022 (rank : 77)
Query Neighborhood Hits	68	Target Neighborhood Hits	1385	Shared Neighborhood Hits	6
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

UN45A_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.048624 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

PERQ1_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.017142 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	215	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

RL35_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.116205 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P42766, Q4VBY5, Q5JTN5, Q6IBC7, Q96QJ7, Q9BYF4	Gene names	RPL35
Domain Architecture	No domain graphic available
Description	60S ribosomal protein L35.

K1949_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.016268 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

PKP3_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.069655 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

SFPQ_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.008923 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	958	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

2AAA_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.020783 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

TBCC_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.015931 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q15814	Gene names	TBCC
Domain Architecture
Description	Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC).

VCX3_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.016328 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.013205 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

DBNL_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.012940 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

VCX1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.012620 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

WNK1_HUMAN
θ value	5.27518 (rank : 58)	NC score	-0.001012 (rank : 78)
Query Neighborhood Hits	68	Target Neighborhood Hits	1158	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

APC_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.037999 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	603	Shared Neighborhood Hits	25
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.039268 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CALD1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.000848 (rank : 76)
Query Neighborhood Hits	68	Target Neighborhood Hits	959	Shared Neighborhood Hits	5
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CLAP1_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.015190 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

NVL_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.005538 (rank : 74)
Query Neighborhood Hits	68	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PKP3_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.066877 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

CF081_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.031336 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q80X86, Q9D564, Q9DAN7	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf81 homolog.

K1219_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.006169 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

NOP14_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.004854 (rank : 75)
Query Neighborhood Hits	68	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PRGC1_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.005994 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

CF081_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.060509 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T9G4, Q8NEB2, Q96LL8	Gene names	C6orf81
Domain Architecture	No domain graphic available
Description	Protein C6orf81.

GCN1L_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.052751 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

PKP1_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.068448 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.065666 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.061051 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

SARM1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.061918 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SARM1_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.062747 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

TNPO2_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.081527 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.082964 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TRIPC_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.091522 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

Hits sorted by NC score

IMA5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
NC score	0.992762 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA1_HUMAN
NC score	0.991482 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.991340 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA7_MOUSE
NC score	0.991276 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA2_MOUSE
NC score	0.974478 (rank : 6)	θ value	1.13238e-127 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
NC score	0.972242 (rank : 7)	θ value	3.64273e-126 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA3_MOUSE
NC score	0.972133 (rank : 8)	θ value	1.92707e-135 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.972039 (rank : 9)	θ value	3.6343e-134 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA4_HUMAN
NC score	0.970810 (rank : 10)	θ value	6.41512e-131 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	32
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
NC score	0.970373 (rank : 11)	θ value	5.43074e-130 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

SPAG6_HUMAN
NC score	0.640789 (rank : 12)	θ value	8.95645e-16 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

SPAG6_MOUSE
NC score	0.637872 (rank : 13)	θ value	4.44505e-15 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

GDS1_HUMAN
NC score	0.306536 (rank : 14)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

ARMC4_HUMAN
NC score	0.286632 (rank : 15)	θ value	1.43324e-05 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

PKP4_MOUSE
NC score	0.177495 (rank : 16)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

CTNB1_MOUSE
NC score	0.175603 (rank : 17)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.175562 (rank : 18)	θ value	0.0113563 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.175290 (rank : 19)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PKP4_HUMAN
NC score	0.175243 (rank : 20)	θ value	0.0148317 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	107	Shared Neighborhood Hits	29
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND2_MOUSE
NC score	0.145260 (rank : 21)	θ value	0.0193708 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.145200 (rank : 22)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	333	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PLAK_HUMAN
NC score	0.138087 (rank : 23)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

CTND1_MOUSE
NC score	0.130756 (rank : 24)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

ARVC_HUMAN
NC score	0.130195 (rank : 25)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
NC score	0.129298 (rank : 26)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

IMB1_MOUSE
NC score	0.127826 (rank : 27)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

CTND1_HUMAN
NC score	0.122122 (rank : 28)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

RL35_HUMAN
NC score	0.116205 (rank : 29)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P42766, Q4VBY5, Q5JTN5, Q6IBC7, Q96QJ7, Q9BYF4	Gene names	RPL35
Domain Architecture	No domain graphic available
Description	60S ribosomal protein L35.

IMB1_HUMAN
NC score	0.106684 (rank : 30)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

TNPO1_HUMAN
NC score	0.099123 (rank : 31)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
NC score	0.095373 (rank : 32)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TRIPC_HUMAN
NC score	0.091522 (rank : 33)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	68	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ARMX3_MOUSE
NC score	0.085504 (rank : 34)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

ARMX3_HUMAN
NC score	0.084915 (rank : 35)	θ value	0.00298849 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

TNPO2_MOUSE
NC score	0.082964 (rank : 36)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.081527 (rank : 37)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

ARMX1_HUMAN
NC score	0.078134 (rank : 38)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

PKP3_HUMAN
NC score	0.069655 (rank : 39)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

ARMX1_MOUSE
NC score	0.069644 (rank : 40)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

PKP1_HUMAN
NC score	0.068448 (rank : 41)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP3_MOUSE
NC score	0.066877 (rank : 42)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PKP1_MOUSE
NC score	0.065666 (rank : 43)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

SARM1_MOUSE
NC score	0.062747 (rank : 44)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	68	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SARM1_HUMAN
NC score	0.061918 (rank : 45)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

PKP2_HUMAN
NC score	0.061051 (rank : 46)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

CF081_HUMAN
NC score	0.060509 (rank : 47)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T9G4, Q8NEB2, Q96LL8	Gene names	C6orf81
Domain Architecture	No domain graphic available
Description	Protein C6orf81.

UN45A_HUMAN
NC score	0.059043 (rank : 48)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

GCN1L_HUMAN
NC score	0.052751 (rank : 49)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

UN45A_MOUSE
NC score	0.048624 (rank : 50)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

RELN_MOUSE
NC score	0.046333 (rank : 51)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	235	Shared Neighborhood Hits	7
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

APC_MOUSE
NC score	0.039268 (rank : 52)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.037999 (rank : 53)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	603	Shared Neighborhood Hits	25
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ZFY16_HUMAN
NC score	0.036438 (rank : 54)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

RELN_HUMAN
NC score	0.034327 (rank : 55)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

CF081_MOUSE
NC score	0.031336 (rank : 56)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q80X86, Q9D564, Q9DAN7	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf81 homolog.

2AAA_HUMAN
NC score	0.022641 (rank : 57)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
NC score	0.020783 (rank : 58)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

AGGF1_HUMAN
NC score	0.017551 (rank : 59)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

DBNL_MOUSE
NC score	0.017423 (rank : 60)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

PERQ1_MOUSE
NC score	0.017142 (rank : 61)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	215	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

VCX3_HUMAN
NC score	0.016328 (rank : 62)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

K1949_HUMAN
NC score	0.016268 (rank : 63)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NYC8, Q68CK8, Q6ZUJ6, Q8NDQ4, Q8TF52, Q9BRL9	Gene names	KIAA1949
Domain Architecture	No domain graphic available
Description	Protein KIAA1949.

TBCC_HUMAN
NC score	0.015931 (rank : 64)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q15814	Gene names	TBCC
Domain Architecture
Description	Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC).

CLAP1_HUMAN
NC score	0.015190 (rank : 65)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

VCXC_HUMAN
NC score	0.013205 (rank : 66)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

DBNL_HUMAN
NC score	0.012940 (rank : 67)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

VCX1_HUMAN
NC score	0.012620 (rank : 68)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

SFPQ_HUMAN
NC score	0.011461 (rank : 69)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	986	Shared Neighborhood Hits	7
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
NC score	0.008923 (rank : 70)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	958	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

LRRK2_MOUSE
NC score	0.006957 (rank : 71)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	1359	Shared Neighborhood Hits	6
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

K1219_HUMAN
NC score	0.006169 (rank : 72)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

PRGC1_HUMAN
NC score	0.005994 (rank : 73)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

NVL_MOUSE
NC score	0.005538 (rank : 74)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NOP14_MOUSE
NC score	0.004854 (rank : 75)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CALD1_HUMAN
NC score	0.000848 (rank : 76)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	959	Shared Neighborhood Hits	5
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

TRHY_HUMAN
NC score	0.000022 (rank : 77)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	1385	Shared Neighborhood Hits	6
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WNK1_HUMAN
NC score	-0.001012 (rank : 78)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	1158	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).