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Network neighborhood for query Sequence : TBCC_HUMAN

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TBCC_HUMAN
SwissProt Accessions	Q15814	Gene names	TBCC
Domain Architecture
Description	Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBCC_HUMAN
θ value	6.59259e-152 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q15814	Gene names	TBCC
Domain Architecture
Description	Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC).

XRP2_HUMAN
θ value	2.20094e-22 (rank : 2)	NC score	0.726885 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O75695, Q86XJ7, Q9NU67	Gene names	RP2
Domain Architecture
Description	Protein XRP2.

XRP2_MOUSE
θ value	1.09232e-21 (rank : 3)	NC score	0.724493 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPK2, Q8BLN8, Q8BVQ8, Q8BZP9	Gene names	Rp2, Rp2h
Domain Architecture	No domain graphic available
Description	Protein XRP2.

K1H2_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.052872 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	492	Shared Neighborhood Hits	19
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

KIFC3_HUMAN
θ value	0.0563607 (rank : 5)	NC score	0.060870 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	619	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_MOUSE
θ value	0.0563607 (rank : 6)	NC score	0.061635 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	571	Shared Neighborhood Hits	22
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

K1H7_HUMAN
θ value	0.279714 (rank : 7)	NC score	0.044928 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	369	Shared Neighborhood Hits	19
SwissProt Accessions	O76014	Gene names	KRTHA7, HHA7, HKA7
Domain Architecture
Description	Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7).

CT2NL_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.058925 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	1059	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

SMC2_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.044722 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

GOGA4_MOUSE
θ value	1.06291 (rank : 10)	NC score	0.044035 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	1939	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

K1H1_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.041750 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	450	Shared Neighborhood Hits	20
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

MYH9_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.037905 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	1829	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CING_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.048759 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	1432	Shared Neighborhood Hits	30
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

MY18A_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.039099 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	1989	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ITSN1_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.040297 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	1757	Shared Neighborhood Hits	32
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

XRCC4_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.044484 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

MY18A_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.038532 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	1929	Shared Neighborhood Hits	29
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRIPB_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.041612 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	1587	Shared Neighborhood Hits	29
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CCD21_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.038628 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	1228	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

HGS_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.036584 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	517	Shared Neighborhood Hits	20
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.036673 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IMA5_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.015931 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

A4_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.033012 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.032908 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

ANR26_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.033620 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	1614	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CT2NL_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.050679 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	902	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FMN2_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.020262 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	484	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MYO15_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.020090 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	671	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CING_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.046375 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	1275	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

ITSN1_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.037538 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	1669	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

RIMB1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.038817 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	1376	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPB4_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.044772 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	O15514, Q52LT4	Gene names	POLR2D
Domain Architecture
Description	DNA-directed RNA polymerase II 16 kDa polypeptide (EC 2.7.7.6) (RPB4).

RPB4_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.044772 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7M8, Q6ZWW0, Q78KE6	Gene names	Polr2d
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase II 16 kDa polypeptide (EC 2.7.7.6) (RPB4).

BRE1B_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.039891 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	1040	Shared Neighborhood Hits	27
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.038472 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	970	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CK5P2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.032473 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	1433	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

STIM1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.034367 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	665	Shared Neighborhood Hits	22
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.034349 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	660	Shared Neighborhood Hits	22
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

Hits sorted by NC score

TBCC_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.59259e-152 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q15814	Gene names	TBCC
Domain Architecture
Description	Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC).

XRP2_HUMAN
NC score	0.726885 (rank : 2)	θ value	2.20094e-22 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O75695, Q86XJ7, Q9NU67	Gene names	RP2
Domain Architecture
Description	Protein XRP2.

XRP2_MOUSE
NC score	0.724493 (rank : 3)	θ value	1.09232e-21 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPK2, Q8BLN8, Q8BVQ8, Q8BZP9	Gene names	Rp2, Rp2h
Domain Architecture	No domain graphic available
Description	Protein XRP2.

KIFC3_MOUSE
NC score	0.061635 (rank : 4)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	571	Shared Neighborhood Hits	22
SwissProt Accessions	O35231, Q91YQ2	Gene names	Kifc3
Domain Architecture
Description	Kinesin-like protein KIFC3.

KIFC3_HUMAN
NC score	0.060870 (rank : 5)	θ value	0.0563607 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	619	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BVG8, O75299, Q8IUT3, Q96HW6	Gene names	KIFC3
Domain Architecture
Description	Kinesin-like protein KIFC3.

CT2NL_HUMAN
NC score	0.058925 (rank : 6)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	1059	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

K1H2_HUMAN
NC score	0.052872 (rank : 7)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	492	Shared Neighborhood Hits	19
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

CT2NL_MOUSE
NC score	0.050679 (rank : 8)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	902	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CING_MOUSE
NC score	0.048759 (rank : 9)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	1432	Shared Neighborhood Hits	30
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CING_HUMAN
NC score	0.046375 (rank : 10)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	1275	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

K1H7_HUMAN
NC score	0.044928 (rank : 11)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	369	Shared Neighborhood Hits	19
SwissProt Accessions	O76014	Gene names	KRTHA7, HHA7, HKA7
Domain Architecture
Description	Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7).

RPB4_HUMAN
NC score	0.044772 (rank : 12)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	O15514, Q52LT4	Gene names	POLR2D
Domain Architecture
Description	DNA-directed RNA polymerase II 16 kDa polypeptide (EC 2.7.7.6) (RPB4).

RPB4_MOUSE
NC score	0.044772 (rank : 13)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7M8, Q6ZWW0, Q78KE6	Gene names	Polr2d
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase II 16 kDa polypeptide (EC 2.7.7.6) (RPB4).

SMC2_HUMAN
NC score	0.044722 (rank : 14)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

XRCC4_HUMAN
NC score	0.044484 (rank : 15)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q13426, Q9BS72, Q9UP94	Gene names	XRCC4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

GOGA4_MOUSE
NC score	0.044035 (rank : 16)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	1939	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

K1H1_MOUSE
NC score	0.041750 (rank : 17)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	450	Shared Neighborhood Hits	20
SwissProt Accessions	Q61765	Gene names	Krtha1, Hka1, Krt1-1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (HKA-1).

TRIPB_HUMAN
NC score	0.041612 (rank : 18)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	1587	Shared Neighborhood Hits	29
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ITSN1_HUMAN
NC score	0.040297 (rank : 19)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	1757	Shared Neighborhood Hits	32
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

BRE1B_HUMAN
NC score	0.039891 (rank : 20)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	1040	Shared Neighborhood Hits	27
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MY18A_MOUSE
NC score	0.039099 (rank : 21)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	1989	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RIMB1_MOUSE
NC score	0.038817 (rank : 22)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	1376	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CCD21_HUMAN
NC score	0.038628 (rank : 23)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	1228	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MY18A_HUMAN
NC score	0.038532 (rank : 24)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	1929	Shared Neighborhood Hits	29
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BRE1B_MOUSE
NC score	0.038472 (rank : 25)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	970	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MYH9_MOUSE
NC score	0.037905 (rank : 26)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	1829	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ITSN1_MOUSE
NC score	0.037538 (rank : 27)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	1669	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

HGS_MOUSE
NC score	0.036673 (rank : 28)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	589	Shared Neighborhood Hits	21
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
NC score	0.036584 (rank : 29)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	517	Shared Neighborhood Hits	20
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

STIM1_HUMAN
NC score	0.034367 (rank : 30)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	665	Shared Neighborhood Hits	22
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
NC score	0.034349 (rank : 31)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	660	Shared Neighborhood Hits	22
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

ANR26_HUMAN
NC score	0.033620 (rank : 32)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	1614	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

A4_HUMAN
NC score	0.033012 (rank : 33)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
NC score	0.032908 (rank : 34)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

CK5P2_HUMAN
NC score	0.032473 (rank : 35)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	1433	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

FMN2_HUMAN
NC score	0.020262 (rank : 36)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	484	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MYO15_HUMAN
NC score	0.020090 (rank : 37)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	671	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

IMA5_HUMAN
NC score	0.015931 (rank : 38)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).