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Network neighborhood for query Sequence : PSA5_HUMAN

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PSA5_HUMAN
SwissProt Accessions	P28066, Q6IBF7	Gene names	PSMA5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSA5_HUMAN
θ value	5.24793e-133 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P28066, Q6IBF7	Gene names	PSMA5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

PSA5_MOUSE
θ value	5.24793e-133 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2U1	Gene names	Psma5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

PSA7L_MOUSE
θ value	1.16164e-39 (rank : 3)	NC score	0.922697 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CWH6	Gene names	Psma8, Psma7l
Domain Architecture
Description	Proteasome subunit alpha type 7-like (EC 3.4.25.1).

PSA7_HUMAN
θ value	9.20422e-37 (rank : 4)	NC score	0.934624 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	O14818, Q9BR53, Q9H4K5, Q9UEU8	Gene names	PSMA7
Domain Architecture
Description	Proteasome subunit alpha type 7 (EC 3.4.25.1) (Proteasome subunit RC6- 1) (Proteasome subunit XAPC7).

PSA7L_HUMAN
θ value	2.05049e-36 (rank : 5)	NC score	0.914812 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAA3, Q8IVP4, Q8TA98, Q8TAA2	Gene names	PSMA8, PSMA7L
Domain Architecture
Description	Proteasome subunit alpha type 7-like (EC 3.4.25.1).

PSA7_MOUSE
θ value	2.05049e-36 (rank : 6)	NC score	0.934613 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2U0	Gene names	Psma7
Domain Architecture
Description	Proteasome subunit alpha type 7 (EC 3.4.25.1) (Proteasome subunit RC6- 1).

PSA2_HUMAN
θ value	5.77852e-31 (rank : 7)	NC score	0.922308 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P25787, Q9BU45	Gene names	PSMA2, PSC3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

PSA2_MOUSE
θ value	7.54701e-31 (rank : 8)	NC score	0.922119 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P49722	Gene names	Psma2, Lmpc3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

PSA4_HUMAN
θ value	1.08979e-29 (rank : 9)	NC score	0.909344 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P25789, Q8TBD1	Gene names	PSMA4, PSC9
Domain Architecture
Description	Proteasome subunit alpha type 4 (EC 3.4.25.1) (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L).

PSA4_MOUSE
θ value	1.08979e-29 (rank : 10)	NC score	0.910555 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1P0, Q3THT1	Gene names	Psma4
Domain Architecture
Description	Proteasome subunit alpha type 4 (EC 3.4.25.1) (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L).

PSA3_MOUSE
θ value	1.85889e-29 (rank : 11)	NC score	0.886517 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	O70435	Gene names	Psma3
Domain Architecture
Description	Proteasome subunit alpha type 3 (EC 3.4.25.1) (Proteasome component C8) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome subunit K).

PSA3_HUMAN
θ value	5.40856e-29 (rank : 12)	NC score	0.885485 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	P25788, Q86U83, Q8N1D8, Q9BS70	Gene names	PSMA3, PSC8
Domain Architecture
Description	Proteasome subunit alpha type 3 (EC 3.4.25.1) (Proteasome component C8) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8).

PSA1_HUMAN
θ value	2.27234e-27 (rank : 13)	NC score	0.893278 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P25786, Q9BRV9	Gene names	PSMA1, PROS30, PSC2
Domain Architecture
Description	Proteasome subunit alpha type 1 (EC 3.4.25.1) (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30).

PSA1_MOUSE
θ value	5.06226e-27 (rank : 14)	NC score	0.892597 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1P4	Gene names	Psma1
Domain Architecture
Description	Proteasome subunit alpha type 1 (EC 3.4.25.1) (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain).

PSA6_HUMAN
θ value	1.62847e-25 (rank : 15)	NC score	0.882361 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	20
SwissProt Accessions	P60900, P34062, Q6IB60	Gene names	PSMA6, PROS27
Domain Architecture
Description	Proteasome subunit alpha type 6 (EC 3.4.25.1) (Proteasome iota chain) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (27 kDa prosomal protein) (PROS-27) (p27K).

PSA6_MOUSE
θ value	2.77775e-25 (rank : 16)	NC score	0.881689 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUM9, Q3U6Y2	Gene names	Psma6
Domain Architecture
Description	Proteasome subunit alpha type 6 (EC 3.4.25.1) (Proteasome iota chain) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain).

PSB10_HUMAN
θ value	1.133e-10 (rank : 17)	NC score	0.483655 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	P40306, Q5U098	Gene names	PSMB10, MECL1
Domain Architecture
Description	Proteasome subunit beta type 10 precursor (EC 3.4.25.1) (Proteasome MECl-1) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1).

PSB10_MOUSE
θ value	1.47974e-10 (rank : 18)	NC score	0.495001 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	O35955, O08687, Q99KC5	Gene names	Psmb10, Lmp10, Mecl1
Domain Architecture
Description	Proteasome subunit beta type 10 precursor (EC 3.4.25.1) (Proteasome MECl-1) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1).

PSB8_MOUSE
θ value	1.80886e-08 (rank : 19)	NC score	0.347988 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	P28063, Q3UK42, Q64300, Q792S8, Q7TMX9, Q91VH7	Gene names	Psmb8, Lmp7, Mc13
Domain Architecture
Description	Proteasome subunit beta type 8 precursor (EC 3.4.25.1) (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13).

PSB8_HUMAN
θ value	3.41135e-07 (rank : 20)	NC score	0.336597 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	P28062, Q29824, Q96J48	Gene names	PSMB8, LMP7, RING10, Y2
Domain Architecture
Description	Proteasome subunit beta type 8 precursor (EC 3.4.25.1) (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13).

PSB7_MOUSE
θ value	5.81887e-07 (rank : 21)	NC score	0.363523 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P70195, O09084, Q542F7, Q9CZH4, Q9DCF7	Gene names	Psmb7, Mmc14
Domain Architecture
Description	Proteasome subunit beta type 7 precursor (EC 3.4.25.1) (Proteasome subunit Z) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z).

PSB5_MOUSE
θ value	1.09739e-05 (rank : 22)	NC score	0.367181 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	O55234, Q9R1P2	Gene names	Psmb5
Domain Architecture
Description	Proteasome subunit beta type 5 precursor (EC 3.4.25.1) (Proteasome epsilon chain) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome subunit X) (Proteasome chain 6).

PSB7_HUMAN
θ value	1.09739e-05 (rank : 23)	NC score	0.347597 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q99436, Q96AG8, Q9BWA7	Gene names	PSMB7
Domain Architecture
Description	Proteasome subunit beta type 7 precursor (EC 3.4.25.1) (Proteasome subunit Z) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z).

PSB5_HUMAN
θ value	7.1131e-05 (rank : 24)	NC score	0.360995 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P28074, Q16242, Q6PEW2	Gene names	PSMB5, LMPX
Domain Architecture
Description	Proteasome subunit beta type 5 precursor (EC 3.4.25.1) (Proteasome epsilon chain) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome subunit X) (Proteasome chain 6) (Proteasome subunit MB1).

PSB9_MOUSE
θ value	0.000461057 (rank : 25)	NC score	0.309910 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P28076, O09085, O09151, Q07704, Q60827, Q64278	Gene names	Psmb9, Lmp2
Domain Architecture
Description	Proteasome subunit beta type 9 precursor (EC 3.4.25.1) (Proteasome chain 7) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (RING12 protein) (Low molecular mass protein 2) (LMP-2d).

PSB9_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.301098 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P28065, Q16523	Gene names	PSMB9, LMP2, RING12
Domain Architecture
Description	Proteasome subunit beta type 9 precursor (EC 3.4.25.1) (Proteasome chain 7) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (RING12 protein) (Low molecular mass protein 2).

BPA1_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.010279 (rank : 41)
Query Neighborhood Hits	33	Target Neighborhood Hits	1477	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.010624 (rank : 40)
Query Neighborhood Hits	33	Target Neighborhood Hits	1369	Shared Neighborhood Hits	5
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PSB2_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.148186 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P49721, P31145	Gene names	PSMB2
Domain Architecture
Description	Proteasome subunit beta type 2 (EC 3.4.25.1) (Proteasome component C7- I) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I).

PSB2_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.147940 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1P3	Gene names	Psmb2
Domain Architecture
Description	Proteasome subunit beta type 2 (EC 3.4.25.1) (Proteasome component C7- I) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I).

UBP35_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.011630 (rank : 39)
Query Neighborhood Hits	33	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

BAG5_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.021706 (rank : 38)
Query Neighborhood Hits	33	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL15, O94950, Q86W59	Gene names	BAG5, KIAA0873
Domain Architecture
Description	BAG family molecular chaperone regulator 5 (BCL2-associated athanogene 5) (BAG-5).

BAG5_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.022219 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CI32, Q3TVA8, Q8K175, Q9DAU0	Gene names	Bag5
Domain Architecture	No domain graphic available
Description	BAG family molecular chaperone regulator 5 (BCL2-associated athanogene 5) (BAG-5).

PSB1_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.117499 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	P20618, Q9BWA8	Gene names	PSMB1, PSC5
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

PSB1_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.120434 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	15
SwissProt Accessions	O09061, Q62038, Q62039	Gene names	Psmb1
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

PSB3_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.070046 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P49720, P31147, Q96E27	Gene names	PSMB3
Domain Architecture
Description	Proteasome subunit beta type 3 (EC 3.4.25.1) (Proteasome theta chain) (Proteasome chain 13) (Proteasome component C10-II).

PSB3_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.087569 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R1P1	Gene names	Psmb3
Domain Architecture
Description	Proteasome subunit beta type 3 (EC 3.4.25.1) (Proteasome theta chain) (Proteasome chain 13) (Proteasome component C10-II).

PSB4_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.089231 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P28070, P31148, Q969L6	Gene names	PSMB4
Domain Architecture
Description	Proteasome subunit beta type 4 precursor (EC 3.4.25.1) (Proteasome beta chain) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome chain 3) (HSN3) (HsBPROS26).

PSB4_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.085534 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	P99026, Q62008	Gene names	Psmb4, Lmp3
Domain Architecture
Description	Proteasome subunit beta type 4 precursor (EC 3.4.25.1) (Proteasome beta chain) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome chain 3).

PSB6_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.187926 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P28072, Q96J55	Gene names	PSMB6, LMPY
Domain Architecture
Description	Proteasome subunit beta type 6 precursor (EC 3.4.25.1) (Proteasome delta chain) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome subunit Y).

PSB6_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.187336 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q60692, Q3V240, Q60693, Q8BJX9, Q91VH5	Gene names	Psmb6, Lmp19
Domain Architecture
Description	Proteasome subunit beta type 6 precursor (EC 3.4.25.1) (Proteasome delta chain) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome subunit Y).

Hits sorted by NC score

PSA5_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.24793e-133 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P28066, Q6IBF7	Gene names	PSMA5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

PSA5_MOUSE
NC score	0.999962 (rank : 2)	θ value	5.24793e-133 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2U1	Gene names	Psma5
Domain Architecture
Description	Proteasome subunit alpha type 5 (EC 3.4.25.1) (Proteasome zeta chain) (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain).

PSA7_HUMAN
NC score	0.934624 (rank : 3)	θ value	9.20422e-37 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	O14818, Q9BR53, Q9H4K5, Q9UEU8	Gene names	PSMA7
Domain Architecture
Description	Proteasome subunit alpha type 7 (EC 3.4.25.1) (Proteasome subunit RC6- 1) (Proteasome subunit XAPC7).

PSA7_MOUSE
NC score	0.934613 (rank : 4)	θ value	2.05049e-36 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2U0	Gene names	Psma7
Domain Architecture
Description	Proteasome subunit alpha type 7 (EC 3.4.25.1) (Proteasome subunit RC6- 1).

PSA7L_MOUSE
NC score	0.922697 (rank : 5)	θ value	1.16164e-39 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CWH6	Gene names	Psma8, Psma7l
Domain Architecture
Description	Proteasome subunit alpha type 7-like (EC 3.4.25.1).

PSA2_HUMAN
NC score	0.922308 (rank : 6)	θ value	5.77852e-31 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P25787, Q9BU45	Gene names	PSMA2, PSC3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

PSA2_MOUSE
NC score	0.922119 (rank : 7)	θ value	7.54701e-31 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P49722	Gene names	Psma2, Lmpc3
Domain Architecture
Description	Proteasome subunit alpha type 2 (EC 3.4.25.1) (Proteasome component C3) (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3).

PSA7L_HUMAN
NC score	0.914812 (rank : 8)	θ value	2.05049e-36 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAA3, Q8IVP4, Q8TA98, Q8TAA2	Gene names	PSMA8, PSMA7L
Domain Architecture
Description	Proteasome subunit alpha type 7-like (EC 3.4.25.1).

PSA4_MOUSE
NC score	0.910555 (rank : 9)	θ value	1.08979e-29 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1P0, Q3THT1	Gene names	Psma4
Domain Architecture
Description	Proteasome subunit alpha type 4 (EC 3.4.25.1) (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L).

PSA4_HUMAN
NC score	0.909344 (rank : 10)	θ value	1.08979e-29 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P25789, Q8TBD1	Gene names	PSMA4, PSC9
Domain Architecture
Description	Proteasome subunit alpha type 4 (EC 3.4.25.1) (Proteasome component C9) (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome subunit L).

PSA1_HUMAN
NC score	0.893278 (rank : 11)	θ value	2.27234e-27 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	P25786, Q9BRV9	Gene names	PSMA1, PROS30, PSC2
Domain Architecture
Description	Proteasome subunit alpha type 1 (EC 3.4.25.1) (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain) (30 kDa prosomal protein) (PROS-30).

PSA1_MOUSE
NC score	0.892597 (rank : 12)	θ value	5.06226e-27 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1P4	Gene names	Psma1
Domain Architecture
Description	Proteasome subunit alpha type 1 (EC 3.4.25.1) (Proteasome component C2) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome nu chain).

PSA3_MOUSE
NC score	0.886517 (rank : 13)	θ value	1.85889e-29 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	O70435	Gene names	Psma3
Domain Architecture
Description	Proteasome subunit alpha type 3 (EC 3.4.25.1) (Proteasome component C8) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome subunit K).

PSA3_HUMAN
NC score	0.885485 (rank : 14)	θ value	5.40856e-29 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	P25788, Q86U83, Q8N1D8, Q9BS70	Gene names	PSMA3, PSC8
Domain Architecture
Description	Proteasome subunit alpha type 3 (EC 3.4.25.1) (Proteasome component C8) (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8).

PSA6_HUMAN
NC score	0.882361 (rank : 15)	θ value	1.62847e-25 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	20
SwissProt Accessions	P60900, P34062, Q6IB60	Gene names	PSMA6, PROS27
Domain Architecture
Description	Proteasome subunit alpha type 6 (EC 3.4.25.1) (Proteasome iota chain) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (27 kDa prosomal protein) (PROS-27) (p27K).

PSA6_MOUSE
NC score	0.881689 (rank : 16)	θ value	2.77775e-25 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUM9, Q3U6Y2	Gene names	Psma6
Domain Architecture
Description	Proteasome subunit alpha type 6 (EC 3.4.25.1) (Proteasome iota chain) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain).

PSB10_MOUSE
NC score	0.495001 (rank : 17)	θ value	1.47974e-10 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	O35955, O08687, Q99KC5	Gene names	Psmb10, Lmp10, Mecl1
Domain Architecture
Description	Proteasome subunit beta type 10 precursor (EC 3.4.25.1) (Proteasome MECl-1) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1).

PSB10_HUMAN
NC score	0.483655 (rank : 18)	θ value	1.133e-10 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	P40306, Q5U098	Gene names	PSMB10, MECL1
Domain Architecture
Description	Proteasome subunit beta type 10 precursor (EC 3.4.25.1) (Proteasome MECl-1) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1).

PSB5_MOUSE
NC score	0.367181 (rank : 19)	θ value	1.09739e-05 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	O55234, Q9R1P2	Gene names	Psmb5
Domain Architecture
Description	Proteasome subunit beta type 5 precursor (EC 3.4.25.1) (Proteasome epsilon chain) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome subunit X) (Proteasome chain 6).

PSB7_MOUSE
NC score	0.363523 (rank : 20)	θ value	5.81887e-07 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P70195, O09084, Q542F7, Q9CZH4, Q9DCF7	Gene names	Psmb7, Mmc14
Domain Architecture
Description	Proteasome subunit beta type 7 precursor (EC 3.4.25.1) (Proteasome subunit Z) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z).

PSB5_HUMAN
NC score	0.360995 (rank : 21)	θ value	7.1131e-05 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P28074, Q16242, Q6PEW2	Gene names	PSMB5, LMPX
Domain Architecture
Description	Proteasome subunit beta type 5 precursor (EC 3.4.25.1) (Proteasome epsilon chain) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome subunit X) (Proteasome chain 6) (Proteasome subunit MB1).

PSB8_MOUSE
NC score	0.347988 (rank : 22)	θ value	1.80886e-08 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	P28063, Q3UK42, Q64300, Q792S8, Q7TMX9, Q91VH7	Gene names	Psmb8, Lmp7, Mc13
Domain Architecture
Description	Proteasome subunit beta type 8 precursor (EC 3.4.25.1) (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13).

PSB7_HUMAN
NC score	0.347597 (rank : 23)	θ value	1.09739e-05 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q99436, Q96AG8, Q9BWA7	Gene names	PSMB7
Domain Architecture
Description	Proteasome subunit beta type 7 precursor (EC 3.4.25.1) (Proteasome subunit Z) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z).

PSB8_HUMAN
NC score	0.336597 (rank : 24)	θ value	3.41135e-07 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	P28062, Q29824, Q96J48	Gene names	PSMB8, LMP7, RING10, Y2
Domain Architecture
Description	Proteasome subunit beta type 8 precursor (EC 3.4.25.1) (Proteasome component C13) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13).

PSB9_MOUSE
NC score	0.309910 (rank : 25)	θ value	0.000461057 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P28076, O09085, O09151, Q07704, Q60827, Q64278	Gene names	Psmb9, Lmp2
Domain Architecture
Description	Proteasome subunit beta type 9 precursor (EC 3.4.25.1) (Proteasome chain 7) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (RING12 protein) (Low molecular mass protein 2) (LMP-2d).

PSB9_HUMAN
NC score	0.301098 (rank : 26)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P28065, Q16523	Gene names	PSMB9, LMP2, RING12
Domain Architecture
Description	Proteasome subunit beta type 9 precursor (EC 3.4.25.1) (Proteasome chain 7) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (RING12 protein) (Low molecular mass protein 2).

PSB6_HUMAN
NC score	0.187926 (rank : 27)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P28072, Q96J55	Gene names	PSMB6, LMPY
Domain Architecture
Description	Proteasome subunit beta type 6 precursor (EC 3.4.25.1) (Proteasome delta chain) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome subunit Y).

PSB6_MOUSE
NC score	0.187336 (rank : 28)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	33	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q60692, Q3V240, Q60693, Q8BJX9, Q91VH5	Gene names	Psmb6, Lmp19
Domain Architecture
Description	Proteasome subunit beta type 6 precursor (EC 3.4.25.1) (Proteasome delta chain) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome subunit Y).

PSB2_HUMAN
NC score	0.148186 (rank : 29)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P49721, P31145	Gene names	PSMB2
Domain Architecture
Description	Proteasome subunit beta type 2 (EC 3.4.25.1) (Proteasome component C7- I) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I).

PSB2_MOUSE
NC score	0.147940 (rank : 30)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1P3	Gene names	Psmb2
Domain Architecture
Description	Proteasome subunit beta type 2 (EC 3.4.25.1) (Proteasome component C7- I) (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I).

PSB1_MOUSE
NC score	0.120434 (rank : 31)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	15
SwissProt Accessions	O09061, Q62038, Q62039	Gene names	Psmb1
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

PSB1_HUMAN
NC score	0.117499 (rank : 32)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	P20618, Q9BWA8	Gene names	PSMB1, PSC5
Domain Architecture
Description	Proteasome subunit beta type 1 (EC 3.4.25.1) (Proteasome component C5) (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome gamma chain).

PSB4_HUMAN
NC score	0.089231 (rank : 33)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P28070, P31148, Q969L6	Gene names	PSMB4
Domain Architecture
Description	Proteasome subunit beta type 4 precursor (EC 3.4.25.1) (Proteasome beta chain) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome chain 3) (HSN3) (HsBPROS26).

PSB3_MOUSE
NC score	0.087569 (rank : 34)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R1P1	Gene names	Psmb3
Domain Architecture
Description	Proteasome subunit beta type 3 (EC 3.4.25.1) (Proteasome theta chain) (Proteasome chain 13) (Proteasome component C10-II).

PSB4_MOUSE
NC score	0.085534 (rank : 35)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	P99026, Q62008	Gene names	Psmb4, Lmp3
Domain Architecture
Description	Proteasome subunit beta type 4 precursor (EC 3.4.25.1) (Proteasome beta chain) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome chain 3).

PSB3_HUMAN
NC score	0.070046 (rank : 36)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P49720, P31147, Q96E27	Gene names	PSMB3
Domain Architecture
Description	Proteasome subunit beta type 3 (EC 3.4.25.1) (Proteasome theta chain) (Proteasome chain 13) (Proteasome component C10-II).

BAG5_MOUSE
NC score	0.022219 (rank : 37)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CI32, Q3TVA8, Q8K175, Q9DAU0	Gene names	Bag5
Domain Architecture	No domain graphic available
Description	BAG family molecular chaperone regulator 5 (BCL2-associated athanogene 5) (BAG-5).

BAG5_HUMAN
NC score	0.021706 (rank : 38)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL15, O94950, Q86W59	Gene names	BAG5, KIAA0873
Domain Architecture
Description	BAG family molecular chaperone regulator 5 (BCL2-associated athanogene 5) (BAG-5).

UBP35_HUMAN
NC score	0.011630 (rank : 39)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

BPAEA_HUMAN
NC score	0.010624 (rank : 40)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	1369	Shared Neighborhood Hits	5
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPA1_MOUSE
NC score	0.010279 (rank : 41)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	1477	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).