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Network neighborhood for query Sequence : MGR4_HUMAN

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MGR4_HUMAN
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MGR2_HUMAN
θ value	0 (rank : 1)	NC score	0.984406 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	56	Shared Neighborhood Hits	42
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_HUMAN
θ value	0 (rank : 2)	NC score	0.980595 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_MOUSE
θ value	0 (rank : 3)	NC score	0.980270 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	54	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR4_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR6_HUMAN
θ value	0 (rank : 5)	NC score	0.996535 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	41
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_MOUSE
θ value	0 (rank : 6)	NC score	0.995933 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR7_HUMAN
θ value	0 (rank : 7)	NC score	0.996516 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
θ value	0 (rank : 8)	NC score	0.996618 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR8_HUMAN
θ value	0 (rank : 9)	NC score	0.996601 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_MOUSE
θ value	0 (rank : 10)	NC score	0.996634 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR5_HUMAN
θ value	3.82926e-184 (rank : 11)	NC score	0.977496 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR1_HUMAN
θ value	3.35459e-180 (rank : 12)	NC score	0.976126 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
θ value	4.1007e-178 (rank : 13)	NC score	0.975513 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

CASR_HUMAN
θ value	4.6295e-105 (rank : 14)	NC score	0.942011 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
θ value	4.6295e-105 (rank : 15)	NC score	0.941915 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
θ value	3.24342e-66 (rank : 16)	NC score	0.929501 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

TS1R2_MOUSE
θ value	2.74572e-65 (rank : 17)	NC score	0.910035 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R1_HUMAN
θ value	7.24236e-58 (rank : 18)	NC score	0.898702 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

GPC6A_HUMAN
θ value	8.00737e-57 (rank : 19)	NC score	0.909217 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

TS1R1_MOUSE
θ value	3.974e-56 (rank : 20)	NC score	0.897559 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

GPC6A_MOUSE
θ value	1.15626e-55 (rank : 21)	NC score	0.906529 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_HUMAN
θ value	1.51013e-55 (rank : 22)	NC score	0.900886 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R3_HUMAN
θ value	1.788e-48 (rank : 23)	NC score	0.888289 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

TS1R3_MOUSE
θ value	8.87376e-48 (rank : 24)	NC score	0.888645 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

V2R1B_MOUSE
θ value	2.85459e-46 (rank : 25)	NC score	0.915599 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

GABR1_MOUSE
θ value	1.06045e-08 (rank : 26)	NC score	0.430863 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	139	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_HUMAN
θ value	1.80886e-08 (rank : 27)	NC score	0.430625 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR2_HUMAN
θ value	1.53129e-07 (rank : 28)	NC score	0.552022 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

NMDZ1_HUMAN
θ value	3.19293e-05 (rank : 29)	NC score	0.196808 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GPC5B_MOUSE
θ value	4.1701e-05 (rank : 30)	NC score	0.333330 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

NMDZ1_MOUSE
θ value	5.44631e-05 (rank : 31)	NC score	0.199095 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GP156_MOUSE
θ value	0.00035302 (rank : 32)	NC score	0.170985 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GP156_HUMAN
θ value	0.000786445 (rank : 33)	NC score	0.149576 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GPC5B_HUMAN
θ value	0.00102713 (rank : 34)	NC score	0.302743 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

ANPRC_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.106206 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

GP158_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.202246 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

ANPRC_MOUSE
θ value	0.0736092 (rank : 37)	NC score	0.123566 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

GUC2G_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.053812 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	644	Shared Neighborhood Hits	24
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

GPC5C_MOUSE
θ value	0.0961366 (rank : 39)	NC score	0.171025 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GP158_MOUSE
θ value	0.163984 (rank : 40)	NC score	0.182974 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GPC5C_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.152280 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5D_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.134436 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

S39A4_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.018835 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q78IQ7, Q8CHL4	Gene names	Slc39a4, Zip4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4) (Activated in W/Wv mouse stomach 2) (mAWMS2).

BAI2_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.012664 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

RNF37_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.017163 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

IBP1_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.014928 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

MKNK1_MOUSE
θ value	1.06291 (rank : 47)	NC score	-0.002446 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	811	Shared Neighborhood Hits	3
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).

S6A12_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.003459 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P31651	Gene names	Slc6a12, Gabt2, Gat-2, Gat2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent betaine transporter (Na+/Cl- betaine/GABA transporter) (Sodium- and chloride-dependent GABA transporter 2) (GAT2).

UBP47_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.011176 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

NRK_HUMAN
θ value	1.38821 (rank : 50)	NC score	-0.001979 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	931	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

UBP47_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.010807 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

GRIK2_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.050760 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GPC5D_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.103648 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

NMD3A_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.026669 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

GRIK3_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.027160 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK4_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.021422 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

HPS4_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.016339 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

USH2A_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.000417 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	600	Shared Neighborhood Hits	3
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

GRIK4_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.021523 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

BAI2_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.009998 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.015725 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	246	Shared Neighborhood Hits	9
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.015663 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	250	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

S39A4_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.011631 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5W5, Q7L5S5, Q9H6T8, Q9NXC4	Gene names	SLC39A4, ZIP4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4).

GP179_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.144897 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

RAI3_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.086764 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFJ5, O95357	Gene names	GPRC5A, RAI3, RAIG1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1) (Orphan G-protein coupling receptor PEIG-1).

RAI3_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.113502 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

Hits sorted by NC score

MGR4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR8_MOUSE
NC score	0.996634 (rank : 2)	θ value	0 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR7_MOUSE
NC score	0.996618 (rank : 3)	θ value	0 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR8_HUMAN
NC score	0.996601 (rank : 4)	θ value	0 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR6_HUMAN
NC score	0.996535 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	41
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR7_HUMAN
NC score	0.996516 (rank : 6)	θ value	0 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR6_MOUSE
NC score	0.995933 (rank : 7)	θ value	0 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR2_HUMAN
NC score	0.984406 (rank : 8)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	56	Shared Neighborhood Hits	42
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_HUMAN
NC score	0.980595 (rank : 9)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_MOUSE
NC score	0.980270 (rank : 10)	θ value	0 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	54	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR5_HUMAN
NC score	0.977496 (rank : 11)	θ value	3.82926e-184 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR1_HUMAN
NC score	0.976126 (rank : 12)	θ value	3.35459e-180 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
NC score	0.975513 (rank : 13)	θ value	4.1007e-178 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

CASR_HUMAN
NC score	0.942011 (rank : 14)	θ value	4.6295e-105 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
NC score	0.941915 (rank : 15)	θ value	4.6295e-105 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
NC score	0.929501 (rank : 16)	θ value	3.24342e-66 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

V2R1B_MOUSE
NC score	0.915599 (rank : 17)	θ value	2.85459e-46 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

TS1R2_MOUSE
NC score	0.910035 (rank : 18)	θ value	2.74572e-65 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

GPC6A_HUMAN
NC score	0.909217 (rank : 19)	θ value	8.00737e-57 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

GPC6A_MOUSE
NC score	0.906529 (rank : 20)	θ value	1.15626e-55 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_HUMAN
NC score	0.900886 (rank : 21)	θ value	1.51013e-55 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R1_HUMAN
NC score	0.898702 (rank : 22)	θ value	7.24236e-58 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R1_MOUSE
NC score	0.897559 (rank : 23)	θ value	3.974e-56 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R3_MOUSE
NC score	0.888645 (rank : 24)	θ value	8.87376e-48 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

TS1R3_HUMAN
NC score	0.888289 (rank : 25)	θ value	1.788e-48 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

GABR2_HUMAN
NC score	0.552022 (rank : 26)	θ value	1.53129e-07 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GABR1_MOUSE
NC score	0.430863 (rank : 27)	θ value	1.06045e-08 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	139	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_HUMAN
NC score	0.430625 (rank : 28)	θ value	1.80886e-08 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GPC5B_MOUSE
NC score	0.333330 (rank : 29)	θ value	4.1701e-05 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5B_HUMAN
NC score	0.302743 (rank : 30)	θ value	0.00102713 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GP158_HUMAN
NC score	0.202246 (rank : 31)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

NMDZ1_MOUSE
NC score	0.199095 (rank : 32)	θ value	5.44631e-05 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
NC score	0.196808 (rank : 33)	θ value	3.19293e-05 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GP158_MOUSE
NC score	0.182974 (rank : 34)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GPC5C_MOUSE
NC score	0.171025 (rank : 35)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GP156_MOUSE
NC score	0.170985 (rank : 36)	θ value	0.00035302 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GPC5C_HUMAN
NC score	0.152280 (rank : 37)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GP156_HUMAN
NC score	0.149576 (rank : 38)	θ value	0.000786445 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GP179_HUMAN
NC score	0.144897 (rank : 39)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPC5D_MOUSE
NC score	0.134436 (rank : 40)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

ANPRC_MOUSE
NC score	0.123566 (rank : 41)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

RAI3_MOUSE
NC score	0.113502 (rank : 42)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

ANPRC_HUMAN
NC score	0.106206 (rank : 43)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

GPC5D_HUMAN
NC score	0.103648 (rank : 44)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

RAI3_HUMAN
NC score	0.086764 (rank : 45)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFJ5, O95357	Gene names	GPRC5A, RAI3, RAIG1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1) (Orphan G-protein coupling receptor PEIG-1).

GUC2G_MOUSE
NC score	0.053812 (rank : 46)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	644	Shared Neighborhood Hits	24
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

GRIK2_HUMAN
NC score	0.050760 (rank : 47)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK3_HUMAN
NC score	0.027160 (rank : 48)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

NMD3A_HUMAN
NC score	0.026669 (rank : 49)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

GRIK4_MOUSE
NC score	0.021523 (rank : 50)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK4_HUMAN
NC score	0.021422 (rank : 51)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

S39A4_MOUSE
NC score	0.018835 (rank : 52)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q78IQ7, Q8CHL4	Gene names	Slc39a4, Zip4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4) (Activated in W/Wv mouse stomach 2) (mAWMS2).

RNF37_HUMAN
NC score	0.017163 (rank : 53)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	O94941	Gene names	UBOX5, KIAA0860, RNF37, UBCE7IP5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (U-box domain-containing protein 5).

HPS4_HUMAN
NC score	0.016339 (rank : 54)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

BAI3_HUMAN
NC score	0.015725 (rank : 55)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	246	Shared Neighborhood Hits	9
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.015663 (rank : 56)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	250	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

IBP1_MOUSE
NC score	0.014928 (rank : 57)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

BAI2_MOUSE
NC score	0.012664 (rank : 58)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

S39A4_HUMAN
NC score	0.011631 (rank : 59)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5W5, Q7L5S5, Q9H6T8, Q9NXC4	Gene names	SLC39A4, ZIP4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4).

UBP47_HUMAN
NC score	0.011176 (rank : 60)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_MOUSE
NC score	0.010807 (rank : 61)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

BAI2_HUMAN
NC score	0.009998 (rank : 62)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	332	Shared Neighborhood Hits	7
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

S6A12_MOUSE
NC score	0.003459 (rank : 63)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P31651	Gene names	Slc6a12, Gabt2, Gat-2, Gat2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent betaine transporter (Na+/Cl- betaine/GABA transporter) (Sodium- and chloride-dependent GABA transporter 2) (GAT2).

USH2A_HUMAN
NC score	0.000417 (rank : 64)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	600	Shared Neighborhood Hits	3
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

NRK_HUMAN
NC score	-0.001979 (rank : 65)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	931	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

MKNK1_MOUSE
NC score	-0.002446 (rank : 66)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	811	Shared Neighborhood Hits	3
SwissProt Accessions	O08605	Gene names	Mknk1, Mnk1
Domain Architecture
Description	MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1).