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Network neighborhood for query Sequence : TS1R3_MOUSE

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TS1R3_MOUSE
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TS1R3_HUMAN
θ value	0 (rank : 1)	NC score	0.995669 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

TS1R3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

TS1R1_HUMAN
θ value	3.1986e-114 (rank : 3)	NC score	0.974401 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R1_MOUSE
θ value	1.21547e-113 (rank : 4)	NC score	0.973032 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

GPC6A_MOUSE
θ value	5.11853e-104 (rank : 5)	NC score	0.967194 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	57	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_MOUSE
θ value	5.29683e-101 (rank : 6)	NC score	0.966872 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

GPC6A_HUMAN
θ value	3.21347e-98 (rank : 7)	NC score	0.965996 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

TS1R2_HUMAN
θ value	3.55291e-97 (rank : 8)	NC score	0.967559 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

CASR_HUMAN
θ value	3.56116e-89 (rank : 9)	NC score	0.953692 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
θ value	7.93343e-89 (rank : 10)	NC score	0.953012 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
θ value	2.82823e-78 (rank : 11)	NC score	0.953275 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	45	Shared Neighborhood Hits	32
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

MGR3_HUMAN
θ value	2.66562e-52 (rank : 12)	NC score	0.896620 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR1_HUMAN
θ value	1.32293e-51 (rank : 13)	NC score	0.893867 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
θ value	8.57503e-51 (rank : 14)	NC score	0.893618 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR5_HUMAN
θ value	1.46268e-50 (rank : 15)	NC score	0.894881 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	72	Shared Neighborhood Hits	32
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR2_HUMAN
θ value	3.2585e-50 (rank : 16)	NC score	0.902778 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_MOUSE
θ value	3.2585e-50 (rank : 17)	NC score	0.896083 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	54	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR4_HUMAN
θ value	8.87376e-48 (rank : 18)	NC score	0.888645 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR6_HUMAN
θ value	4.40402e-47 (rank : 19)	NC score	0.883710 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_MOUSE
θ value	1.41672e-45 (rank : 20)	NC score	0.882666 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	30
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR7_HUMAN
θ value	2.41655e-45 (rank : 21)	NC score	0.885189 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
θ value	3.15612e-45 (rank : 22)	NC score	0.885018 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR8_HUMAN
θ value	2.50074e-42 (rank : 23)	NC score	0.883639 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_MOUSE
θ value	9.50281e-42 (rank : 24)	NC score	0.883953 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

V2R1B_MOUSE
θ value	1.52067e-31 (rank : 25)	NC score	0.921060 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

GABR2_HUMAN
θ value	2.79066e-09 (rank : 26)	NC score	0.534080 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GUC2F_HUMAN
θ value	4.45536e-07 (rank : 27)	NC score	0.068127 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	740	Shared Neighborhood Hits	28
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GABR1_HUMAN
θ value	1.09739e-05 (rank : 28)	NC score	0.426901 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	1.09739e-05 (rank : 29)	NC score	0.426466 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

NMDZ1_HUMAN
θ value	0.00035302 (rank : 30)	NC score	0.191625 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	77	Shared Neighborhood Hits	31
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
θ value	0.00134147 (rank : 31)	NC score	0.191771 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	76	Shared Neighborhood Hits	30
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

ANPRA_MOUSE
θ value	0.125558 (rank : 32)	NC score	0.025656 (rank : 50)
Query Neighborhood Hits	49	Target Neighborhood Hits	600	Shared Neighborhood Hits	17
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

LIMK1_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.003637 (rank : 61)
Query Neighborhood Hits	49	Target Neighborhood Hits	1005	Shared Neighborhood Hits	13
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

EPHA4_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.003763 (rank : 60)
Query Neighborhood Hits	49	Target Neighborhood Hits	975	Shared Neighborhood Hits	14
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

TNR4_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.025807 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

GBA3_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.008366 (rank : 55)
Query Neighborhood Hits	49	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

ANPRA_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.021236 (rank : 52)
Query Neighborhood Hits	49	Target Neighborhood Hits	612	Shared Neighborhood Hits	19
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

BPIL2_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.007770 (rank : 56)
Query Neighborhood Hits	49	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFQ6	Gene names	BPIL2
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 2 precursor.

EPHA1_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.007696 (rank : 57)
Query Neighborhood Hits	49	Target Neighborhood Hits	997	Shared Neighborhood Hits	18
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

GUC2E_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.023647 (rank : 51)
Query Neighborhood Hits	49	Target Neighborhood Hits	692	Shared Neighborhood Hits	15
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

PAQRA_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.009882 (rank : 54)
Query Neighborhood Hits	49	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IY49, Q6NVU5, Q6TCH0	Gene names	MMD2, PAQR10
Domain Architecture	No domain graphic available
Description	Monocyte to macrophage differentiation factor 2 (Progestin and adipoQ receptor family member X).

T2R38_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.004477 (rank : 59)
Query Neighborhood Hits	49	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQA6, Q4VHF0	Gene names	Tas2r38, T2r31, Tas2r138
Domain Architecture
Description	Taste receptor type 2 member 38 (T2R38) (T2R138) (mT2R31).

ANPRC_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.092974 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

EPHA4_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.002703 (rank : 63)
Query Neighborhood Hits	49	Target Neighborhood Hits	982	Shared Neighborhood Hits	13
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

GRIK2_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.049593 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GUC2D_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.019521 (rank : 53)
Query Neighborhood Hits	49	Target Neighborhood Hits	715	Shared Neighborhood Hits	14
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

ANPRB_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.026318 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	646	Shared Neighborhood Hits	18
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

EPHA1_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.002706 (rank : 62)
Query Neighborhood Hits	49	Target Neighborhood Hits	958	Shared Neighborhood Hits	14
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

SCUB3_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.006763 (rank : 58)
Query Neighborhood Hits	49	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ANPRC_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.101571 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

GP156_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.084586 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GP156_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.096990 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GP158_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.142539 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.126021 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP179_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.099565 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	372	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPC5B_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.201859 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GPC5B_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.224630 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5C_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.108815 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5C_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.122731 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5D_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.054836 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

GPC5D_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.073568 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

GUC2G_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.050090 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	644	Shared Neighborhood Hits	30
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

RAI3_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.070901 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

Hits sorted by NC score

TS1R3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

TS1R3_HUMAN
NC score	0.995669 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

TS1R1_HUMAN
NC score	0.974401 (rank : 3)	θ value	3.1986e-114 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R1_MOUSE
NC score	0.973032 (rank : 4)	θ value	1.21547e-113 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R2_HUMAN
NC score	0.967559 (rank : 5)	θ value	3.55291e-97 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

GPC6A_MOUSE
NC score	0.967194 (rank : 6)	θ value	5.11853e-104 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	57	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_MOUSE
NC score	0.966872 (rank : 7)	θ value	5.29683e-101 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	69	Shared Neighborhood Hits	36
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

GPC6A_HUMAN
NC score	0.965996 (rank : 8)	θ value	3.21347e-98 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

CASR_HUMAN
NC score	0.953692 (rank : 9)	θ value	3.56116e-89 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
NC score	0.953275 (rank : 10)	θ value	2.82823e-78 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	45	Shared Neighborhood Hits	32
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

CASR_MOUSE
NC score	0.953012 (rank : 11)	θ value	7.93343e-89 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2R1B_MOUSE
NC score	0.921060 (rank : 12)	θ value	1.52067e-31 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

MGR2_HUMAN
NC score	0.902778 (rank : 13)	θ value	3.2585e-50 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_HUMAN
NC score	0.896620 (rank : 14)	θ value	2.66562e-52 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_MOUSE
NC score	0.896083 (rank : 15)	θ value	3.2585e-50 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	54	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR5_HUMAN
NC score	0.894881 (rank : 16)	θ value	1.46268e-50 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	72	Shared Neighborhood Hits	32
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR1_HUMAN
NC score	0.893867 (rank : 17)	θ value	1.32293e-51 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
NC score	0.893618 (rank : 18)	θ value	8.57503e-51 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR4_HUMAN
NC score	0.888645 (rank : 19)	θ value	8.87376e-48 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR7_HUMAN
NC score	0.885189 (rank : 20)	θ value	2.41655e-45 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
NC score	0.885018 (rank : 21)	θ value	3.15612e-45 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR8_MOUSE
NC score	0.883953 (rank : 22)	θ value	9.50281e-42 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR6_HUMAN
NC score	0.883710 (rank : 23)	θ value	4.40402e-47 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR8_HUMAN
NC score	0.883639 (rank : 24)	θ value	2.50074e-42 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR6_MOUSE
NC score	0.882666 (rank : 25)	θ value	1.41672e-45 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	30
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

GABR2_HUMAN
NC score	0.534080 (rank : 26)	θ value	2.79066e-09 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GABR1_HUMAN
NC score	0.426901 (rank : 27)	θ value	1.09739e-05 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.426466 (rank : 28)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GPC5B_MOUSE
NC score	0.224630 (rank : 29)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	49	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5B_HUMAN
NC score	0.201859 (rank : 30)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	49	Target Neighborhood Hits	28	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

NMDZ1_MOUSE
NC score	0.191771 (rank : 31)	θ value	0.00134147 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	76	Shared Neighborhood Hits	30
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
NC score	0.191625 (rank : 32)	θ value	0.00035302 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	77	Shared Neighborhood Hits	31
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GP158_HUMAN
NC score	0.142539 (rank : 33)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	49	Target Neighborhood Hits	221	Shared Neighborhood Hits	17
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_MOUSE
NC score	0.126021 (rank : 34)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	49	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GPC5C_MOUSE
NC score	0.122731 (rank : 35)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	49	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5C_HUMAN
NC score	0.108815 (rank : 36)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

ANPRC_MOUSE
NC score	0.101571 (rank : 37)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

GP179_HUMAN
NC score	0.099565 (rank : 38)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	49	Target Neighborhood Hits	372	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GP156_MOUSE
NC score	0.096990 (rank : 39)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	49	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

ANPRC_HUMAN
NC score	0.092974 (rank : 40)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

GP156_HUMAN
NC score	0.084586 (rank : 41)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	49	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GPC5D_MOUSE
NC score	0.073568 (rank : 42)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	49	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

RAI3_MOUSE
NC score	0.070901 (rank : 43)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	49	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

GUC2F_HUMAN
NC score	0.068127 (rank : 44)	θ value	4.45536e-07 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	740	Shared Neighborhood Hits	28
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GPC5D_HUMAN
NC score	0.054836 (rank : 45)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	49	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

GUC2G_MOUSE
NC score	0.050090 (rank : 46)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	49	Target Neighborhood Hits	644	Shared Neighborhood Hits	30
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

GRIK2_HUMAN
NC score	0.049593 (rank : 47)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

ANPRB_HUMAN
NC score	0.026318 (rank : 48)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	646	Shared Neighborhood Hits	18
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

TNR4_MOUSE
NC score	0.025807 (rank : 49)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

ANPRA_MOUSE
NC score	0.025656 (rank : 50)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	600	Shared Neighborhood Hits	17
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

GUC2E_MOUSE
NC score	0.023647 (rank : 51)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	692	Shared Neighborhood Hits	15
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

ANPRA_HUMAN
NC score	0.021236 (rank : 52)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	612	Shared Neighborhood Hits	19
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

GUC2D_HUMAN
NC score	0.019521 (rank : 53)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	715	Shared Neighborhood Hits	14
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

PAQRA_HUMAN
NC score	0.009882 (rank : 54)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IY49, Q6NVU5, Q6TCH0	Gene names	MMD2, PAQR10
Domain Architecture	No domain graphic available
Description	Monocyte to macrophage differentiation factor 2 (Progestin and adipoQ receptor family member X).

GBA3_HUMAN
NC score	0.008366 (rank : 55)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H227, Q3MIH4, Q53GG8, Q6NSF4, Q8NHT8, Q9H3T4, Q9H4C6	Gene names	GBA3, CBG, CBGL1
Domain Architecture	No domain graphic available
Description	Cytosolic beta-glucosidase (EC 3.2.1.21) (Cytosolic beta-glucosidase- like protein 1).

BPIL2_HUMAN
NC score	0.007770 (rank : 56)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFQ6	Gene names	BPIL2
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 2 precursor.

EPHA1_HUMAN
NC score	0.007696 (rank : 57)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	997	Shared Neighborhood Hits	18
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

SCUB3_HUMAN
NC score	0.006763 (rank : 58)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

T2R38_MOUSE
NC score	0.004477 (rank : 59)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQA6, Q4VHF0	Gene names	Tas2r38, T2r31, Tas2r138
Domain Architecture
Description	Taste receptor type 2 member 38 (T2R38) (T2R138) (mT2R31).

EPHA4_HUMAN
NC score	0.003763 (rank : 60)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	975	Shared Neighborhood Hits	14
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

LIMK1_HUMAN
NC score	0.003637 (rank : 61)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	1005	Shared Neighborhood Hits	13
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

EPHA1_MOUSE
NC score	0.002706 (rank : 62)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	958	Shared Neighborhood Hits	14
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA4_MOUSE
NC score	0.002703 (rank : 63)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	982	Shared Neighborhood Hits	13
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).