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Network neighborhood for query Sequence : PGRP2_HUMAN

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PGRP2_HUMAN
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PGRP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).

PGRP2_MOUSE
θ value	0 (rank : 2)	NC score	0.990723 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCS0, Q8K4I8, Q9QXZ1, Q9QXZ2	Gene names	Pglyrp2, Pglyrpl, Pgrpl
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2) (TagL).

PGRP_HUMAN
θ value	1.16434e-31 (rank : 3)	NC score	0.841724 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O75594	Gene names	PGLYRP1, PGLYRP, PGRP
Domain Architecture
Description	Peptidoglycan recognition protein precursor (PGRP-S).

PGRP3_HUMAN
θ value	4.42448e-31 (rank : 4)	NC score	0.806161 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LB9	Gene names	PGLYRP3, PGRPIA
Domain Architecture
Description	Peptidoglycan recognition protein I-alpha precursor (Peptidoglycan recognition protein intermediate alpha) (PGRP-I-alpha) (PGLYRPIalpha) (Peptidoglycan recognition protein 3).

PGRP4_HUMAN
θ value	1.92365e-26 (rank : 5)	NC score	0.785922 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LB8, Q9HD75	Gene names	PGLYRP4, PGRPIB
Domain Architecture
Description	Peptidoglycan recognition protein I-beta precursor (Peptidoglycan recognition protein intermediate beta) (PGRP-I-beta) (PGLYRPIbeta) (Peptidoglycan recognition protein 4).

PGRP_MOUSE
θ value	3.28125e-26 (rank : 6)	NC score	0.828460 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	O88593, Q62185	Gene names	Pglyrp1, Pglyrp, Pgrp, Pgrps, Tag7
Domain Architecture
Description	Peptidoglycan recognition protein precursor (Peptidoglycan recognition protein short) (PGRP-S) (Cytokine tag7).

DOT1L_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.066392 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	660	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

URP2_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.028984 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

CRSP2_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.038639 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	380	Shared Neighborhood Hits	3
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

AATK_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.006110 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	1243	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

DAG1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.042590 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

TRAK2_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.017943 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	476	Shared Neighborhood Hits	3
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TRM1_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.028811 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

LAP4_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.008478 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	590	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

DAG1_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.037310 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

LAT_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.022834 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	O43561, O43919	Gene names	LAT
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

PLXA1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.005884 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

LAP4_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.006643 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	608	Shared Neighborhood Hits	3
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

RIPK3_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.001224 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	828	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

Hits sorted by NC score

PGRP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q96PD5, Q96N74, Q9UC60	Gene names	PGLYRP2, PGLYRPL, PGRPL
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2).

PGRP2_MOUSE
NC score	0.990723 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCS0, Q8K4I8, Q9QXZ1, Q9QXZ2	Gene names	Pglyrp2, Pglyrpl, Pgrpl
Domain Architecture
Description	N-acetylmuramoyl-L-alanine amidase precursor (EC 3.5.1.28) (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2) (TagL).

PGRP_HUMAN
NC score	0.841724 (rank : 3)	θ value	1.16434e-31 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	O75594	Gene names	PGLYRP1, PGLYRP, PGRP
Domain Architecture
Description	Peptidoglycan recognition protein precursor (PGRP-S).

PGRP_MOUSE
NC score	0.828460 (rank : 4)	θ value	3.28125e-26 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	O88593, Q62185	Gene names	Pglyrp1, Pglyrp, Pgrp, Pgrps, Tag7
Domain Architecture
Description	Peptidoglycan recognition protein precursor (Peptidoglycan recognition protein short) (PGRP-S) (Cytokine tag7).

PGRP3_HUMAN
NC score	0.806161 (rank : 5)	θ value	4.42448e-31 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LB9	Gene names	PGLYRP3, PGRPIA
Domain Architecture
Description	Peptidoglycan recognition protein I-alpha precursor (Peptidoglycan recognition protein intermediate alpha) (PGRP-I-alpha) (PGLYRPIalpha) (Peptidoglycan recognition protein 3).

PGRP4_HUMAN
NC score	0.785922 (rank : 6)	θ value	1.92365e-26 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LB8, Q9HD75	Gene names	PGLYRP4, PGRPIB
Domain Architecture
Description	Peptidoglycan recognition protein I-beta precursor (Peptidoglycan recognition protein intermediate beta) (PGRP-I-beta) (PGLYRPIbeta) (Peptidoglycan recognition protein 4).

DOT1L_HUMAN
NC score	0.066392 (rank : 7)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	660	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DAG1_HUMAN
NC score	0.042590 (rank : 8)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

CRSP2_HUMAN
NC score	0.038639 (rank : 9)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	380	Shared Neighborhood Hits	3
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

DAG1_MOUSE
NC score	0.037310 (rank : 10)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

URP2_MOUSE
NC score	0.028984 (rank : 11)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K1B8	Gene names	Urp2, Kind3
Domain Architecture
Description	Unc-112-related protein 2 (Kindlin-3).

TRM1_HUMAN
NC score	0.028811 (rank : 12)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

LAT_HUMAN
NC score	0.022834 (rank : 13)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	O43561, O43919	Gene names	LAT
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

TRAK2_HUMAN
NC score	0.017943 (rank : 14)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	476	Shared Neighborhood Hits	3
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

LAP4_MOUSE
NC score	0.008478 (rank : 15)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	590	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

LAP4_HUMAN
NC score	0.006643 (rank : 16)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	608	Shared Neighborhood Hits	3
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

AATK_HUMAN
NC score	0.006110 (rank : 17)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	1243	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

PLXA1_HUMAN
NC score	0.005884 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

RIPK3_HUMAN
NC score	0.001224 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	828	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).