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Network neighborhood for query Sequence : SEN54_HUMAN

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SEN54_HUMAN
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEN54_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

SEN54_MOUSE
θ value	0 (rank : 2)	NC score	0.989861 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2A2, Q9DCI5	Gene names	Tsen54, Sen54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54).

BSN_MOUSE
θ value	0.163984 (rank : 3)	NC score	0.037371 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	2057	Shared Neighborhood Hits	10
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

EP300_HUMAN
θ value	0.47712 (rank : 4)	NC score	0.034201 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	821	Shared Neighborhood Hits	8
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

TCGAP_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.026634 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	872	Shared Neighborhood Hits	9
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BAG3_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.044039 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	513	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

NUMA1_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.013836 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	1523	Shared Neighborhood Hits	6
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CT174_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.045964 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

NACAM_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.019594 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	1866	Shared Neighborhood Hits	12
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NRAP_MOUSE
θ value	1.81305 (rank : 10)	NC score	0.025158 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	167	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

CKAP2_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.046512 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

CEBPA_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.021002 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CENPE_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.006382 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	2060	Shared Neighborhood Hits	8
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DPPA2_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.028416 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7J5, Q8WVF0	Gene names	DPPA2, PESCRG1
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 2 (Pluripotent embryonic stem cell-related protein 1).

GMIP_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.019199 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

OCLN_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.024911 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

SORC2_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.015217 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

KCNK3_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.012976 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

AMFR2_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.014023 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

BAG3_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.038079 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	314	Shared Neighborhood Hits	6
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

FOG1_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.006294 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	981	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

RR22_MOUSE
θ value	6.88961 (rank : 22)	NC score	0.009703 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	201	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K5A4	Gene names	Rrp22
Domain Architecture	No domain graphic available
Description	Ras-like protein RRP22 (RAS-related protein on chromosome 22 homolog).

SI1L1_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.008725 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

Hits sorted by NC score

SEN54_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

SEN54_MOUSE
NC score	0.989861 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C2A2, Q9DCI5	Gene names	Tsen54, Sen54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54).

CKAP2_HUMAN
NC score	0.046512 (rank : 3)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

CT174_HUMAN
NC score	0.045964 (rank : 4)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

BAG3_MOUSE
NC score	0.044039 (rank : 5)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	513	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BAG3_HUMAN
NC score	0.038079 (rank : 6)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	314	Shared Neighborhood Hits	6
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BSN_MOUSE
NC score	0.037371 (rank : 7)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	2057	Shared Neighborhood Hits	10
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

EP300_HUMAN
NC score	0.034201 (rank : 8)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	821	Shared Neighborhood Hits	8
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

DPPA2_HUMAN
NC score	0.028416 (rank : 9)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7J5, Q8WVF0	Gene names	DPPA2, PESCRG1
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 2 (Pluripotent embryonic stem cell-related protein 1).

TCGAP_HUMAN
NC score	0.026634 (rank : 10)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	872	Shared Neighborhood Hits	9
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

NRAP_MOUSE
NC score	0.025158 (rank : 11)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	167	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XB4, O35884, Q3UTY7, Q3UU10, Q80V40	Gene names	Nrap
Domain Architecture	No domain graphic available
Description	Nebulin-related anchoring protein (N-RAP).

OCLN_HUMAN
NC score	0.024911 (rank : 12)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

CEBPA_HUMAN
NC score	0.021002 (rank : 13)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

NACAM_MOUSE
NC score	0.019594 (rank : 14)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	1866	Shared Neighborhood Hits	12
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

GMIP_HUMAN
NC score	0.019199 (rank : 15)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

SORC2_HUMAN
NC score	0.015217 (rank : 16)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

AMFR2_HUMAN
NC score	0.014023 (rank : 17)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

NUMA1_HUMAN
NC score	0.013836 (rank : 18)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	1523	Shared Neighborhood Hits	6
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

KCNK3_MOUSE
NC score	0.012976 (rank : 19)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

RR22_MOUSE
NC score	0.009703 (rank : 20)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	201	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K5A4	Gene names	Rrp22
Domain Architecture	No domain graphic available
Description	Ras-like protein RRP22 (RAS-related protein on chromosome 22 homolog).

SI1L1_HUMAN
NC score	0.008725 (rank : 21)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

CENPE_HUMAN
NC score	0.006382 (rank : 22)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	2060	Shared Neighborhood Hits	8
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FOG1_HUMAN
NC score	0.006294 (rank : 23)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	981	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).