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Network neighborhood for query Sequence : AOC3_HUMAN

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AOC3_HUMAN
SwissProt Accessions	Q16853, Q45F94	Gene names	AOC3, VAP1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1) (HPAO).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AOC2_HUMAN
θ value	0 (rank : 1)	NC score	0.994074 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	O75106, O00120, O75105, Q4TTW5, Q9UNY0	Gene names	AOC2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

AOC2_MOUSE
θ value	0 (rank : 2)	NC score	0.993088 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q812C9, Q80WP3	Gene names	Aoc2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

AOC3_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q16853, Q45F94	Gene names	AOC3, VAP1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1) (HPAO).

AOC3_MOUSE
θ value	0 (rank : 4)	NC score	0.997547 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O70423, Q66JM4, Q9R055	Gene names	Aoc3, Vap1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1).

ABP1_HUMAN
θ value	2.12077e-150 (rank : 5)	NC score	0.966881 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P19801, Q16683, Q16684, Q56II4, Q6GU42	Gene names	ABP1, AOC1, DAO1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase) (Kidney amine oxidase) (KAO).

ABP1_MOUSE
θ value	1.37464e-149 (rank : 6)	NC score	0.966531 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZQ5, Q8R229, Q8VC36	Gene names	Abp1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase).

TCGAP_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.027908 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	409	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SORC3_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.023359 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

BSN_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.013600 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	2057	Shared Neighborhood Hits	6
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FX4L1_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.016264 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NU39	Gene names	FOXD4L1
Domain Architecture
Description	Forkhead box protein D4-like 1.

FOXD4_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.015765 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q12950, Q5VVK1, Q8WXT6	Gene names	FOXD4, FKHL9, FOXD4A, FREAC5
Domain Architecture
Description	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead- related transcription factor 5) (FREAC-5) (Myeloid factor-alpha).

CHKA_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.015824 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	O54804, Q8BPL3, Q8BPW6, Q9CXP3, Q9QX56	Gene names	Chka, Chk
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

CK045_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.052736 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAV5	Gene names	C11orf45
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C11orf45 precursor.

SORC3_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.019245 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

LDB3_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.006847 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	497	Shared Neighborhood Hits	4
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LTB4D_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.013407 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q14914, Q8IYQ0, Q9H1X6	Gene names	LTB4DH
Domain Architecture
Description	NADP-dependent leukotriene B4 12-hydroxydehydrogenase (EC 1.3.1.74) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48).

CU013_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.009398 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	405	Shared Neighborhood Hits	2
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

GFC1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.021825 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

NEUR4_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.017535 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

ZP4_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.009316 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

DUT_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.015852 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

FX4L4_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.009234 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXT5	Gene names	FOXD4L4, FOXD4B
Domain Architecture
Description	Forkhead box protein D4-like 4 (Forkhead box protein D4B) (Myeloid factor-gamma).

IRS2_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.006763 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PA24B_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.004406 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

Hits sorted by NC score

AOC3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q16853, Q45F94	Gene names	AOC3, VAP1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1) (HPAO).

AOC3_MOUSE
NC score	0.997547 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	O70423, Q66JM4, Q9R055	Gene names	Aoc3, Vap1
Domain Architecture
Description	Membrane copper amine oxidase (EC 1.4.3.6) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1).

AOC2_HUMAN
NC score	0.994074 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	O75106, O00120, O75105, Q4TTW5, Q9UNY0	Gene names	AOC2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

AOC2_MOUSE
NC score	0.993088 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q812C9, Q80WP3	Gene names	Aoc2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

ABP1_HUMAN
NC score	0.966881 (rank : 5)	θ value	2.12077e-150 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P19801, Q16683, Q16684, Q56II4, Q6GU42	Gene names	ABP1, AOC1, DAO1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase) (Kidney amine oxidase) (KAO).

ABP1_MOUSE
NC score	0.966531 (rank : 6)	θ value	1.37464e-149 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8JZQ5, Q8R229, Q8VC36	Gene names	Abp1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase).

CK045_HUMAN
NC score	0.052736 (rank : 7)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAV5	Gene names	C11orf45
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C11orf45 precursor.

TCGAP_MOUSE
NC score	0.027908 (rank : 8)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	409	Shared Neighborhood Hits	5
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SORC3_HUMAN
NC score	0.023359 (rank : 9)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

GFC1_HUMAN
NC score	0.021825 (rank : 10)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P63117	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein].

SORC3_MOUSE
NC score	0.019245 (rank : 11)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

NEUR4_HUMAN
NC score	0.017535 (rank : 12)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWR8, Q96D64	Gene names	NEU4
Domain Architecture
Description	Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4).

FX4L1_HUMAN
NC score	0.016264 (rank : 13)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NU39	Gene names	FOXD4L1
Domain Architecture
Description	Forkhead box protein D4-like 1.

DUT_HUMAN
NC score	0.015852 (rank : 14)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

CHKA_MOUSE
NC score	0.015824 (rank : 15)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	O54804, Q8BPL3, Q8BPW6, Q9CXP3, Q9QX56	Gene names	Chka, Chk
Domain Architecture
Description	Choline kinase alpha (EC 2.7.1.32) (CK) (CHETK-alpha).

FOXD4_HUMAN
NC score	0.015765 (rank : 16)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q12950, Q5VVK1, Q8WXT6	Gene names	FOXD4, FKHL9, FOXD4A, FREAC5
Domain Architecture
Description	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead- related transcription factor 5) (FREAC-5) (Myeloid factor-alpha).

BSN_MOUSE
NC score	0.013600 (rank : 17)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	2057	Shared Neighborhood Hits	6
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LTB4D_HUMAN
NC score	0.013407 (rank : 18)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q14914, Q8IYQ0, Q9H1X6	Gene names	LTB4DH
Domain Architecture
Description	NADP-dependent leukotriene B4 12-hydroxydehydrogenase (EC 1.3.1.74) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48).

CU013_HUMAN
NC score	0.009398 (rank : 19)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	405	Shared Neighborhood Hits	2
SwissProt Accessions	O95447	Gene names	C21orf13
Domain Architecture
Description	Protein C21orf13.

ZP4_HUMAN
NC score	0.009316 (rank : 20)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

FX4L4_HUMAN
NC score	0.009234 (rank : 21)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXT5	Gene names	FOXD4L4, FOXD4B
Domain Architecture
Description	Forkhead box protein D4-like 4 (Forkhead box protein D4B) (Myeloid factor-gamma).

LDB3_HUMAN
NC score	0.006847 (rank : 22)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	497	Shared Neighborhood Hits	4
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

IRS2_HUMAN
NC score	0.006763 (rank : 23)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

PA24B_MOUSE
NC score	0.004406 (rank : 24)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).