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Network neighborhood for query Sequence : CK042_HUMAN

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CK042_HUMAN
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CK042_HUMAN
θ value	9.13544e-178 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.

MILK1_MOUSE
θ value	0.21417 (rank : 2)	NC score	0.052284 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	788	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NACAM_MOUSE
θ value	0.47712 (rank : 3)	NC score	0.043115 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	1866	Shared Neighborhood Hits	13
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCLO_MOUSE
θ value	1.38821 (rank : 4)	NC score	0.031084 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	2275	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CSPG5_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.048403 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

OBSCN_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.010935 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	1931	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SORC1_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.026660 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

PDE3B_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.019868 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

PRRT3_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.033392 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	998	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

HAIR_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.024224 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	172	Shared Neighborhood Hits	2
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

SLIK1_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.010698 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	333	Shared Neighborhood Hits	2
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

ZN687_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.010198 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	1244	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ARHG1_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.022134 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CEL_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.014290 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	896	Shared Neighborhood Hits	11
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SOCS7_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.025209 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SRBP1_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.028992 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	384	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ARHG1_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.020284 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

IF4G1_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.019172 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	534	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MISS_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.025315 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NOS1_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.012465 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

TCF7_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.013525 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

WNK4_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.006575 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	961	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

Hits sorted by NC score

CK042_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.13544e-178 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N5U0	Gene names	C11orf42
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf42.

MILK1_MOUSE
NC score	0.052284 (rank : 2)	θ value	0.21417 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	788	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CSPG5_HUMAN
NC score	0.048403 (rank : 3)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	199	Shared Neighborhood Hits	5
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

NACAM_MOUSE
NC score	0.043115 (rank : 4)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	1866	Shared Neighborhood Hits	13
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRRT3_HUMAN
NC score	0.033392 (rank : 5)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	998	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PCLO_MOUSE
NC score	0.031084 (rank : 6)	θ value	1.38821 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	2275	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SRBP1_MOUSE
NC score	0.028992 (rank : 7)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	384	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SORC1_MOUSE
NC score	0.026660 (rank : 8)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

MISS_MOUSE
NC score	0.025315 (rank : 9)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

SOCS7_MOUSE
NC score	0.025209 (rank : 10)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

HAIR_HUMAN
NC score	0.024224 (rank : 11)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	172	Shared Neighborhood Hits	2
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

ARHG1_MOUSE
NC score	0.022134 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ARHG1_HUMAN
NC score	0.020284 (rank : 13)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

PDE3B_HUMAN
NC score	0.019868 (rank : 14)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

IF4G1_MOUSE
NC score	0.019172 (rank : 15)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	534	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

CEL_HUMAN
NC score	0.014290 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	896	Shared Neighborhood Hits	11
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TCF7_MOUSE
NC score	0.013525 (rank : 17)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

NOS1_HUMAN
NC score	0.012465 (rank : 18)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

OBSCN_HUMAN
NC score	0.010935 (rank : 19)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	1931	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SLIK1_MOUSE
NC score	0.010698 (rank : 20)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	333	Shared Neighborhood Hits	2
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

ZN687_HUMAN
NC score	0.010198 (rank : 21)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	1244	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

WNK4_MOUSE
NC score	0.006575 (rank : 22)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	961	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).