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Network neighborhood for query Sequence : FBX42_HUMAN

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FBX42_HUMAN
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBX42_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	121	Target Neighborhood Hits	121	Shared Neighborhood Hits	121
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBX42_MOUSE
θ value	0 (rank : 2)	NC score	0.984870 (rank : 2)
Query Neighborhood Hits	121	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

KLDC1_MOUSE
θ value	2.60593e-15 (rank : 3)	NC score	0.615130 (rank : 3)
Query Neighborhood Hits	121	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YG3	Gene names	Klhdc1
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 1.

KLDC1_HUMAN
θ value	4.91457e-14 (rank : 4)	NC score	0.602596 (rank : 5)
Query Neighborhood Hits	121	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N7A1, Q8WYI1	Gene names	KLHDC1
Domain Architecture
Description	Kelch domain-containing protein 1.

HCFC1_MOUSE
θ value	1.09485e-13 (rank : 5)	NC score	0.497956 (rank : 13)
Query Neighborhood Hits	121	Target Neighborhood Hits	348	Shared Neighborhood Hits	44
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_HUMAN
θ value	2.43908e-13 (rank : 6)	NC score	0.498835 (rank : 12)
Query Neighborhood Hits	121	Target Neighborhood Hits	331	Shared Neighborhood Hits	40
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

KLDC2_MOUSE
θ value	1.2105e-12 (rank : 7)	NC score	0.604909 (rank : 4)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q4G5Y1, Q99JY2, Q9D784	Gene names	Klhdc2
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Endothelial differentiation inhibitory protein TNG).

KLDC2_HUMAN
θ value	2.0648e-12 (rank : 8)	NC score	0.602306 (rank : 6)
Query Neighborhood Hits	121	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2U9, Q6IAF0	Gene names	KLHDC2, HCA33
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP).

HCFC2_HUMAN
θ value	6.00763e-12 (rank : 9)	NC score	0.525580 (rank : 11)
Query Neighborhood Hits	121	Target Neighborhood Hits	154	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

KLDC4_MOUSE
θ value	2.28291e-11 (rank : 10)	NC score	0.562563 (rank : 8)
Query Neighborhood Hits	121	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q921I2, Q8CIK0	Gene names	Klhdc4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

KLDC3_HUMAN
θ value	3.89403e-11 (rank : 11)	NC score	0.548228 (rank : 9)
Query Neighborhood Hits	121	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQ90	Gene names	KLHDC3, PEAS
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

KLDC3_MOUSE
θ value	8.67504e-11 (rank : 12)	NC score	0.545225 (rank : 10)
Query Neighborhood Hits	121	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VEM9, Q3TCN9, Q3UR95, Q91XU6, Q99JH9, Q9DBG8	Gene names	Klhdc3, Peas
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

KLDC4_HUMAN
θ value	1.47974e-10 (rank : 13)	NC score	0.571080 (rank : 7)
Query Neighborhood Hits	121	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TBB5, Q96F29, Q9BVN3	Gene names	KLHDC4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

LZTR1_HUMAN
θ value	9.59137e-10 (rank : 14)	NC score	0.399272 (rank : 15)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

LZTR1_MOUSE
θ value	9.59137e-10 (rank : 15)	NC score	0.402613 (rank : 14)
Query Neighborhood Hits	121	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

MEGF8_MOUSE
θ value	3.08544e-08 (rank : 16)	NC score	0.247941 (rank : 16)
Query Neighborhood Hits	121	Target Neighborhood Hits	520	Shared Neighborhood Hits	29
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
θ value	1.17247e-07 (rank : 17)	NC score	0.223989 (rank : 19)
Query Neighborhood Hits	121	Target Neighborhood Hits	528	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ATRN_MOUSE
θ value	7.59969e-07 (rank : 18)	NC score	0.242972 (rank : 17)
Query Neighborhood Hits	121	Target Neighborhood Hits	519	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATRN_HUMAN
θ value	3.19293e-05 (rank : 19)	NC score	0.234692 (rank : 18)
Query Neighborhood Hits	121	Target Neighborhood Hits	525	Shared Neighborhood Hits	33
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

KLH22_MOUSE
θ value	0.00035302 (rank : 20)	NC score	0.092154 (rank : 30)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q99JN2, Q8BT13	Gene names	Klhl22, Kelchl
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

MAGE1_HUMAN
θ value	0.00102713 (rank : 21)	NC score	0.070370 (rank : 44)
Query Neighborhood Hits	121	Target Neighborhood Hits	1389	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

KLH22_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.093380 (rank : 29)
Query Neighborhood Hits	121	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q53GT1, Q96B68, Q96KC6	Gene names	KLHL22
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

ARMX2_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.066467 (rank : 48)
Query Neighborhood Hits	121	Target Neighborhood Hits	349	Shared Neighborhood Hits	16
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ENC1_MOUSE
θ value	0.0563607 (rank : 24)	NC score	0.100101 (rank : 25)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	27
SwissProt Accessions	O35709	Gene names	Enc1, Enc-1
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1).

FBSP1_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.085483 (rank : 32)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

MUC13_MOUSE
θ value	0.0736092 (rank : 26)	NC score	0.065778 (rank : 50)
Query Neighborhood Hits	121	Target Neighborhood Hits	447	Shared Neighborhood Hits	18
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ENC1_HUMAN
θ value	0.163984 (rank : 27)	NC score	0.094358 (rank : 27)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	O14682, O75464, Q9UPG9	Gene names	ENC1, NRPB, PIG10
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced protein 10) (Nuclear matrix protein NRP/B).

FBX28_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.110677 (rank : 23)
Query Neighborhood Hits	121	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

MDC1_HUMAN
θ value	0.163984 (rank : 29)	NC score	0.054012 (rank : 69)
Query Neighborhood Hits	121	Target Neighborhood Hits	1446	Shared Neighborhood Hits	29
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

YETS2_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.072282 (rank : 43)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

KLDC5_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.097907 (rank : 26)
Query Neighborhood Hits	121	Target Neighborhood Hits	83	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2K6, Q2VPK1, Q8N334	Gene names	KLHDC5, KIAA1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KLH23_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.086455 (rank : 31)
Query Neighborhood Hits	121	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

CSPG3_MOUSE
θ value	0.279714 (rank : 33)	NC score	0.023333 (rank : 103)
Query Neighborhood Hits	121	Target Neighborhood Hits	657	Shared Neighborhood Hits	17
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FBXL5_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.066548 (rank : 47)
Query Neighborhood Hits	121	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

FOXL1_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.014336 (rank : 119)
Query Neighborhood Hits	121	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

PNRC1_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.065345 (rank : 51)
Query Neighborhood Hits	121	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q12796, Q5T7J6	Gene names	PNRC1, PROL2
Domain Architecture	No domain graphic available
Description	Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (B4-2 protein).

KLDC5_MOUSE
θ value	0.47712 (rank : 37)	NC score	0.085105 (rank : 33)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BFQ9, Q6ZPT4	Gene names	Klhdc5, Kiaa1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

BAG3_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.048268 (rank : 74)
Query Neighborhood Hits	121	Target Neighborhood Hits	314	Shared Neighborhood Hits	19
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CI082_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.038209 (rank : 82)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDY9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82 homolog.

FBXL5_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.060595 (rank : 55)
Query Neighborhood Hits	121	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

KLD7B_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.073887 (rank : 39)
Query Neighborhood Hits	121	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q96G42	Gene names	KLHDC7B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 7B.

NFH_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.025240 (rank : 100)
Query Neighborhood Hits	121	Target Neighborhood Hits	2247	Shared Neighborhood Hits	41
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CU056_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.035095 (rank : 85)
Query Neighborhood Hits	121	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0A9, Q9NSE5	Gene names	C21orf56
Domain Architecture	No domain graphic available
Description	Putative protein C21orf56.

FBX2_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.042980 (rank : 81)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UK22, Q6FGJ7, Q8TB29, Q9UKC6	Gene names	FBXO2, FBX2
Domain Architecture
Description	F-box only protein 2.

FBX2_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.047410 (rank : 75)
Query Neighborhood Hits	121	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q80UW2, Q8R0D2	Gene names	Fbxo2, Fbx2
Domain Architecture	No domain graphic available
Description	F-box only protein 2.

LCMT2_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.100376 (rank : 24)
Query Neighborhood Hits	121	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYR1, Q3T9F7, Q6A048, Q8BIG6	Gene names	Lcmt2, Kiaa0547
Domain Architecture	No domain graphic available
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

MAML1_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.033612 (rank : 88)
Query Neighborhood Hits	121	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SPT5H_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.044337 (rank : 77)
Query Neighborhood Hits	121	Target Neighborhood Hits	436	Shared Neighborhood Hits	20
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.045397 (rank : 76)
Query Neighborhood Hits	121	Target Neighborhood Hits	437	Shared Neighborhood Hits	23
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TNNT1_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.037344 (rank : 83)
Query Neighborhood Hits	121	Target Neighborhood Hits	211	Shared Neighborhood Hits	6
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

BRSK1_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.002216 (rank : 149)
Query Neighborhood Hits	121	Target Neighborhood Hits	942	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

IRS1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.022608 (rank : 104)
Query Neighborhood Hits	121	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NACAM_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.043884 (rank : 79)
Query Neighborhood Hits	121	Target Neighborhood Hits	1866	Shared Neighborhood Hits	39
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NUPL2_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.031211 (rank : 90)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

OBSCN_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.004691 (rank : 143)
Query Neighborhood Hits	121	Target Neighborhood Hits	1931	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PCLO_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.029713 (rank : 93)
Query Neighborhood Hits	121	Target Neighborhood Hits	2046	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.031966 (rank : 89)
Query Neighborhood Hits	121	Target Neighborhood Hits	2275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RUNX2_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.036661 (rank : 84)
Query Neighborhood Hits	121	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

CSF1_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.029877 (rank : 92)
Query Neighborhood Hits	121	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

DLX4_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.009469 (rank : 132)
Query Neighborhood Hits	121	Target Neighborhood Hits	352	Shared Neighborhood Hits	7
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

RIN2_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.018244 (rank : 112)
Query Neighborhood Hits	121	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

SRRM2_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.043033 (rank : 80)
Query Neighborhood Hits	121	Target Neighborhood Hits	1470	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCP10_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.029117 (rank : 95)
Query Neighborhood Hits	121	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

BRD2_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.013966 (rank : 120)
Query Neighborhood Hits	121	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

RUNX2_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.033707 (rank : 87)
Query Neighborhood Hits	121	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SEPT9_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.018215 (rank : 113)
Query Neighborhood Hits	121	Target Neighborhood Hits	706	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

BRCA2_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.027093 (rank : 98)
Query Neighborhood Hits	121	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

EPAS1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.009538 (rank : 131)
Query Neighborhood Hits	121	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HME2_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.006239 (rank : 139)
Query Neighborhood Hits	121	Target Neighborhood Hits	355	Shared Neighborhood Hits	6
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

MNAB_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.023941 (rank : 102)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MSPD3_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.020942 (rank : 110)
Query Neighborhood Hits	121	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O75425, O75423, O75424	Gene names	MOSPD3
Domain Architecture	No domain graphic available
Description	Motile sperm domain-containing protein 3.

MTMR3_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.009017 (rank : 134)
Query Neighborhood Hits	121	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

MUC1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.044147 (rank : 78)
Query Neighborhood Hits	121	Target Neighborhood Hits	388	Shared Neighborhood Hits	21
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PAPOG_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.024984 (rank : 101)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

PAPOG_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.027072 (rank : 99)
Query Neighborhood Hits	121	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

PHLB2_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.006435 (rank : 138)
Query Neighborhood Hits	121	Target Neighborhood Hits	1016	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PKN1_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.000559 (rank : 151)
Query Neighborhood Hits	121	Target Neighborhood Hits	886	Shared Neighborhood Hits	12
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

SPEG_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.010122 (rank : 130)
Query Neighborhood Hits	121	Target Neighborhood Hits	1959	Shared Neighborhood Hits	41
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZC3H3_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.021115 (rank : 108)
Query Neighborhood Hits	121	Target Neighborhood Hits	159	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ARI1A_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.022119 (rank : 106)
Query Neighborhood Hits	121	Target Neighborhood Hits	787	Shared Neighborhood Hits	26
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BSN_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.030620 (rank : 91)
Query Neighborhood Hits	121	Target Neighborhood Hits	1537	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DDX51_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.006837 (rank : 137)
Query Neighborhood Hits	121	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

FBXL7_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.022521 (rank : 105)
Query Neighborhood Hits	121	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

INVS_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.005802 (rank : 140)
Query Neighborhood Hits	121	Target Neighborhood Hits	455	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

KHL15_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.072973 (rank : 42)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	25
SwissProt Accessions	Q96M94, Q32MN3, Q8NDA3, Q96BM6, Q9C0I6	Gene names	KLHL15, KIAA1677
Domain Architecture	No domain graphic available
Description	Kelch-like protein 15.

M3K12_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.000792 (rank : 150)
Query Neighborhood Hits	121	Target Neighborhood Hits	940	Shared Neighborhood Hits	10
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MKLN1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.131557 (rank : 21)
Query Neighborhood Hits	121	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UL63, Q9NSK4, Q9NUS8	Gene names	MKLN1
Domain Architecture
Description	Muskelin.

MN1_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.028798 (rank : 96)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

NKX61_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.006935 (rank : 136)
Query Neighborhood Hits	121	Target Neighborhood Hits	439	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

XKR7_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.011265 (rank : 122)
Query Neighborhood Hits	121	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

ZBT16_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.003164 (rank : 147)
Query Neighborhood Hits	121	Target Neighborhood Hits	1010	Shared Neighborhood Hits	20
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

CPSF6_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.020564 (rank : 111)
Query Neighborhood Hits	121	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

EVX2_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.004513 (rank : 144)
Query Neighborhood Hits	121	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q03828	Gene names	EVX2
Domain Architecture
Description	Homeobox even-skipped homolog protein 2 (EVX-2).

FBX27_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.027444 (rank : 97)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

JHD2B_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.010129 (rank : 129)
Query Neighborhood Hits	121	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

JIP3_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.007219 (rank : 135)
Query Neighborhood Hits	121	Target Neighborhood Hits	759	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MAGC1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.020945 (rank : 109)
Query Neighborhood Hits	121	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PP16A_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.004330 (rank : 145)
Query Neighborhood Hits	121	Target Neighborhood Hits	340	Shared Neighborhood Hits	6
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PRGC2_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.014357 (rank : 118)
Query Neighborhood Hits	121	Target Neighborhood Hits	272	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

PRRT3_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.021454 (rank : 107)
Query Neighborhood Hits	121	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PUM1_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.016974 (rank : 115)
Query Neighborhood Hits	121	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q14671, Q5VXY7, Q9HAN1	Gene names	PUM1, KIAA0099, PUMH1
Domain Architecture
Description	Pumilio homolog 1 (Pumilio-1) (HsPUM).

PUM1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.016965 (rank : 116)
Query Neighborhood Hits	121	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6	Gene names	Pum1, Kiaa0099
Domain Architecture
Description	Pumilio homolog 1.

SP4_HUMAN
θ value	6.88961 (rank : 103)	NC score	-0.001148 (rank : 153)
Query Neighborhood Hits	121	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

SSPO_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.010652 (rank : 125)
Query Neighborhood Hits	121	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SYN3_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.013966 (rank : 121)
Query Neighborhood Hits	121	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

ANK2_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.010614 (rank : 126)
Query Neighborhood Hits	121	Target Neighborhood Hits	1615	Shared Neighborhood Hits	36
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR43_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.009256 (rank : 133)
Query Neighborhood Hits	121	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ARHGC_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.004065 (rank : 146)
Query Neighborhood Hits	121	Target Neighborhood Hits	344	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BAG4_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.034215 (rank : 86)
Query Neighborhood Hits	121	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CI61, Q3TRL9, Q91VT5, Q9CWG2	Gene names	Bag4, Sodd
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

M3K1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.000296 (rank : 152)
Query Neighborhood Hits	121	Target Neighborhood Hits	952	Shared Neighborhood Hits	12
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MCA1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.010822 (rank : 123)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q12904, Q6FG28, Q96CQ9	Gene names	SCYE1, EMAP2
Domain Architecture
Description	Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)].

MKLN1_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.124266 (rank : 22)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	O89050	Gene names	Mkln1
Domain Architecture
Description	Muskelin.

PCNT_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.004972 (rank : 142)
Query Neighborhood Hits	121	Target Neighborhood Hits	1207	Shared Neighborhood Hits	13
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PHF12_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.029138 (rank : 94)
Query Neighborhood Hits	121	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

RBNS5_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.015797 (rank : 117)
Query Neighborhood Hits	121	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

RU17_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.005500 (rank : 141)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SALL3_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.002328 (rank : 148)
Query Neighborhood Hits	121	Target Neighborhood Hits	1066	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TLN1_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.010545 (rank : 127)
Query Neighborhood Hits	121	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.010693 (rank : 124)
Query Neighborhood Hits	121	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

ZMYM1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.010309 (rank : 128)
Query Neighborhood Hits	121	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SVZ6, Q7Z3Q4	Gene names	ZMYM1
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 1.

ZNT1_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.017966 (rank : 114)
Query Neighborhood Hits	121	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6M5, Q9BZF6	Gene names	SLC30A1, ZNT1
Domain Architecture
Description	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1).

BKLH5_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.062387 (rank : 54)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	24
SwissProt Accessions	Q96NJ5, Q96PY7	Gene names	BKLHD5, KIAA1900
Domain Architecture
Description	BTB and kelch domain-containing protein 5.

BTBD5_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.052741 (rank : 71)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

GAN_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.053116 (rank : 70)
Query Neighborhood Hits	121	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2C0	Gene names	GAN, GAN1, KLHL16
Domain Architecture
Description	Gigaxonin (Kelch-like protein 16).

HCFC2_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.175586 (rank : 20)
Query Neighborhood Hits	121	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

KBTB9_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.059431 (rank : 56)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	24
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KBTB9_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.058851 (rank : 59)
Query Neighborhood Hits	121	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KBTBA_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.056145 (rank : 62)
Query Neighborhood Hits	121	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

KEAP1_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.055773 (rank : 64)
Query Neighborhood Hits	121	Target Neighborhood Hits	181	Shared Neighborhood Hits	23
SwissProt Accessions	Q14145, Q6LEP0	Gene names	KEAP1, KIAA0132, KLHL19
Domain Architecture	No domain graphic available
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (Kelch-like protein 19).

KEAP1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.054211 (rank : 67)
Query Neighborhood Hits	121	Target Neighborhood Hits	182	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

KLD8A_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.093815 (rank : 28)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IYD2, Q9NVG5	Gene names	KLHDC8A
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLD8A_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.080164 (rank : 34)
Query Neighborhood Hits	121	Target Neighborhood Hits	85	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XA8	Gene names	Klhdc8a
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLD8B_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.064655 (rank : 52)
Query Neighborhood Hits	121	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLD8B_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.063383 (rank : 53)
Query Neighborhood Hits	121	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLH10_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.058701 (rank : 60)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	23
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLH10_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.055866 (rank : 63)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLH12_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.058955 (rank : 58)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q53G59, Q9HBX5	Gene names	KLHL12, C3IP1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

KLH12_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.059077 (rank : 57)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BZM0, Q8K225	Gene names	Klhl12, C3ip1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

KLH13_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.073068 (rank : 41)
Query Neighborhood Hits	121	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLH13_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.076672 (rank : 37)
Query Neighborhood Hits	121	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q80TF4, Q9DBY7	Gene names	Klhl13, Bklhd2, Kiaa1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLH14_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.079198 (rank : 35)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

KLH18_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.066072 (rank : 49)
Query Neighborhood Hits	121	Target Neighborhood Hits	143	Shared Neighborhood Hits	24
SwissProt Accessions	O94889, Q8N125	Gene names	KLHL18, KIAA0795
Domain Architecture
Description	Kelch-like protein 18.

KLH23_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.067909 (rank : 46)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

KLH26_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.055720 (rank : 65)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q53HC5, Q8TAP0, Q9NUX3	Gene names	KLHL26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

KLHL1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.058153 (rank : 61)
Query Neighborhood Hits	121	Target Neighborhood Hits	195	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NR64, Q5VZ64, Q9H4X4, Q9NR65, Q9P238	Gene names	KLHL1, KIAA1490
Domain Architecture
Description	Kelch-like protein 1.

KLHL1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.054123 (rank : 68)
Query Neighborhood Hits	121	Target Neighborhood Hits	193	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

KLHL4_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.068525 (rank : 45)
Query Neighborhood Hits	121	Target Neighborhood Hits	212	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

KLHL5_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.055440 (rank : 66)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PQ7, Q86XW0, Q9NUK3, Q9NV27, Q9NVA9, Q9Y2X2	Gene names	KLHL5
Domain Architecture
Description	Kelch-like protein 5.

KLHL7_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.050356 (rank : 73)
Query Neighborhood Hits	121	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IXQ5, Q9BQF8	Gene names	KLHL7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

KLHL7_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.050944 (rank : 72)
Query Neighborhood Hits	121	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BUL5, Q9CZP4	Gene names	Klhl7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

KLHL9_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.076545 (rank : 38)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2J3, Q8TCQ2	Gene names	KLHL9, KIAA1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

KLHL9_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.078729 (rank : 36)
Query Neighborhood Hits	121	Target Neighborhood Hits	195	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

LCMT2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.073390 (rank : 40)
Query Neighborhood Hits	121	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	O60294, Q4JFT6, Q96B55, Q9NR10	Gene names	LCMT2, KIAA0547
Domain Architecture
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

Hits sorted by NC score

FBX42_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	121	Target Neighborhood Hits	121	Shared Neighborhood Hits	121
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBX42_MOUSE
NC score	0.984870 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	121	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

KLDC1_MOUSE
NC score	0.615130 (rank : 3)	θ value	2.60593e-15 (rank : 3)
Query Neighborhood Hits	121	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q80YG3	Gene names	Klhdc1
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 1.

KLDC2_MOUSE
NC score	0.604909 (rank : 4)	θ value	1.2105e-12 (rank : 7)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q4G5Y1, Q99JY2, Q9D784	Gene names	Klhdc2
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Endothelial differentiation inhibitory protein TNG).

KLDC1_HUMAN
NC score	0.602596 (rank : 5)	θ value	4.91457e-14 (rank : 4)
Query Neighborhood Hits	121	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N7A1, Q8WYI1	Gene names	KLHDC1
Domain Architecture
Description	Kelch domain-containing protein 1.

KLDC2_HUMAN
NC score	0.602306 (rank : 6)	θ value	2.0648e-12 (rank : 8)
Query Neighborhood Hits	121	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2U9, Q6IAF0	Gene names	KLHDC2, HCA33
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP).

KLDC4_HUMAN
NC score	0.571080 (rank : 7)	θ value	1.47974e-10 (rank : 13)
Query Neighborhood Hits	121	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TBB5, Q96F29, Q9BVN3	Gene names	KLHDC4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

KLDC4_MOUSE
NC score	0.562563 (rank : 8)	θ value	2.28291e-11 (rank : 10)
Query Neighborhood Hits	121	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q921I2, Q8CIK0	Gene names	Klhdc4
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 4.

KLDC3_HUMAN
NC score	0.548228 (rank : 9)	θ value	3.89403e-11 (rank : 11)
Query Neighborhood Hits	121	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BQ90	Gene names	KLHDC3, PEAS
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

KLDC3_MOUSE
NC score	0.545225 (rank : 10)	θ value	8.67504e-11 (rank : 12)
Query Neighborhood Hits	121	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VEM9, Q3TCN9, Q3UR95, Q91XU6, Q99JH9, Q9DBG8	Gene names	Klhdc3, Peas
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein).

HCFC2_HUMAN
NC score	0.525580 (rank : 11)	θ value	6.00763e-12 (rank : 9)
Query Neighborhood Hits	121	Target Neighborhood Hits	154	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HCFC1_HUMAN
NC score	0.498835 (rank : 12)	θ value	2.43908e-13 (rank : 6)
Query Neighborhood Hits	121	Target Neighborhood Hits	331	Shared Neighborhood Hits	40
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC1_MOUSE
NC score	0.497956 (rank : 13)	θ value	1.09485e-13 (rank : 5)
Query Neighborhood Hits	121	Target Neighborhood Hits	348	Shared Neighborhood Hits	44
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

LZTR1_MOUSE
NC score	0.402613 (rank : 14)	θ value	9.59137e-10 (rank : 15)
Query Neighborhood Hits	121	Target Neighborhood Hits	200	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

LZTR1_HUMAN
NC score	0.399272 (rank : 15)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

MEGF8_MOUSE
NC score	0.247941 (rank : 16)	θ value	3.08544e-08 (rank : 16)
Query Neighborhood Hits	121	Target Neighborhood Hits	520	Shared Neighborhood Hits	29
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

ATRN_MOUSE
NC score	0.242972 (rank : 17)	θ value	7.59969e-07 (rank : 18)
Query Neighborhood Hits	121	Target Neighborhood Hits	519	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATRN_HUMAN
NC score	0.234692 (rank : 18)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	121	Target Neighborhood Hits	525	Shared Neighborhood Hits	33
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

MEGF8_HUMAN
NC score	0.223989 (rank : 19)	θ value	1.17247e-07 (rank : 17)
Query Neighborhood Hits	121	Target Neighborhood Hits	528	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

HCFC2_MOUSE
NC score	0.175586 (rank : 20)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	121	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

MKLN1_HUMAN
NC score	0.131557 (rank : 21)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	121	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UL63, Q9NSK4, Q9NUS8	Gene names	MKLN1
Domain Architecture
Description	Muskelin.

MKLN1_MOUSE
NC score	0.124266 (rank : 22)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	O89050	Gene names	Mkln1
Domain Architecture
Description	Muskelin.

FBX28_HUMAN
NC score	0.110677 (rank : 23)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	121	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVF7, O75070	Gene names	FBXO28, KIAA0483
Domain Architecture	No domain graphic available
Description	F-box only protein 28.

LCMT2_MOUSE
NC score	0.100376 (rank : 24)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	121	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYR1, Q3T9F7, Q6A048, Q8BIG6	Gene names	Lcmt2, Kiaa0547
Domain Architecture	No domain graphic available
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

ENC1_MOUSE
NC score	0.100101 (rank : 25)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	27
SwissProt Accessions	O35709	Gene names	Enc1, Enc-1
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1).

KLDC5_HUMAN
NC score	0.097907 (rank : 26)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	121	Target Neighborhood Hits	83	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2K6, Q2VPK1, Q8N334	Gene names	KLHDC5, KIAA1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

ENC1_HUMAN
NC score	0.094358 (rank : 27)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	27
SwissProt Accessions	O14682, O75464, Q9UPG9	Gene names	ENC1, NRPB, PIG10
Domain Architecture
Description	Ectoderm-neural cortex 1 protein (ENC-1) (p53-induced protein 10) (Nuclear matrix protein NRP/B).

KLD8A_HUMAN
NC score	0.093815 (rank : 28)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IYD2, Q9NVG5	Gene names	KLHDC8A
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLH22_HUMAN
NC score	0.093380 (rank : 29)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	121	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q53GT1, Q96B68, Q96KC6	Gene names	KLHL22
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

KLH22_MOUSE
NC score	0.092154 (rank : 30)	θ value	0.00035302 (rank : 20)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q99JN2, Q8BT13	Gene names	Klhl22, Kelchl
Domain Architecture	No domain graphic available
Description	Kelch-like protein 22.

KLH23_HUMAN
NC score	0.086455 (rank : 31)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	121	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

FBSP1_MOUSE
NC score	0.085483 (rank : 32)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

KLDC5_MOUSE
NC score	0.085105 (rank : 33)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BFQ9, Q6ZPT4	Gene names	Klhdc5, Kiaa1340
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 5.

KLD8A_MOUSE
NC score	0.080164 (rank : 34)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	121	Target Neighborhood Hits	85	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XA8	Gene names	Klhdc8a
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8A.

KLH14_HUMAN
NC score	0.079198 (rank : 35)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2G3	Gene names	KLHL14, KIAA1384
Domain Architecture	No domain graphic available
Description	Kelch-like protein 14.

KLHL9_MOUSE
NC score	0.078729 (rank : 36)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	121	Target Neighborhood Hits	195	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

KLH13_MOUSE
NC score	0.076672 (rank : 37)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	121	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q80TF4, Q9DBY7	Gene names	Klhl13, Bklhd2, Kiaa1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLHL9_HUMAN
NC score	0.076545 (rank : 38)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2J3, Q8TCQ2	Gene names	KLHL9, KIAA1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

KLD7B_HUMAN
NC score	0.073887 (rank : 39)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	121	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q96G42	Gene names	KLHDC7B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 7B.

LCMT2_HUMAN
NC score	0.073390 (rank : 40)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	121	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	O60294, Q4JFT6, Q96B55, Q9NR10	Gene names	LCMT2, KIAA0547
Domain Architecture
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

KLH13_HUMAN
NC score	0.073068 (rank : 41)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	121	Target Neighborhood Hits	193	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KHL15_HUMAN
NC score	0.072973 (rank : 42)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	25
SwissProt Accessions	Q96M94, Q32MN3, Q8NDA3, Q96BM6, Q9C0I6	Gene names	KLHL15, KIAA1677
Domain Architecture	No domain graphic available
Description	Kelch-like protein 15.

YETS2_MOUSE
NC score	0.072282 (rank : 43)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

MAGE1_HUMAN
NC score	0.070370 (rank : 44)	θ value	0.00102713 (rank : 21)
Query Neighborhood Hits	121	Target Neighborhood Hits	1389	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

KLHL4_HUMAN
NC score	0.068525 (rank : 45)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	121	Target Neighborhood Hits	212	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0H6, Q9Y3J5	Gene names	KLHL4, KIAA1687
Domain Architecture
Description	Kelch-like protein 4.

KLH23_MOUSE
NC score	0.067909 (rank : 46)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

FBXL5_MOUSE
NC score	0.066548 (rank : 47)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	121	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C2S5, Q3TWC9, Q80XI5, Q8BGF5, Q8BNL3, Q8C3Q8	Gene names	Fbxl5
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5).

ARMX2_MOUSE
NC score	0.066467 (rank : 48)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	121	Target Neighborhood Hits	349	Shared Neighborhood Hits	16
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

KLH18_HUMAN
NC score	0.066072 (rank : 49)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	121	Target Neighborhood Hits	143	Shared Neighborhood Hits	24
SwissProt Accessions	O94889, Q8N125	Gene names	KLHL18, KIAA0795
Domain Architecture
Description	Kelch-like protein 18.

MUC13_MOUSE
NC score	0.065778 (rank : 50)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	121	Target Neighborhood Hits	447	Shared Neighborhood Hits	18
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PNRC1_HUMAN
NC score	0.065345 (rank : 51)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	121	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q12796, Q5T7J6	Gene names	PNRC1, PROL2
Domain Architecture	No domain graphic available
Description	Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (B4-2 protein).

KLD8B_HUMAN
NC score	0.064655 (rank : 52)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	121	Target Neighborhood Hits	80	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IXV7	Gene names	KLHDC8B
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

KLD8B_MOUSE
NC score	0.063383 (rank : 53)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	121	Target Neighborhood Hits	80	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D2D9	Gene names	Klhdc8b
Domain Architecture	No domain graphic available
Description	Kelch domain-containing protein 8B.

BKLH5_HUMAN
NC score	0.062387 (rank : 54)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	24
SwissProt Accessions	Q96NJ5, Q96PY7	Gene names	BKLHD5, KIAA1900
Domain Architecture
Description	BTB and kelch domain-containing protein 5.

FBXL5_HUMAN
NC score	0.060595 (rank : 55)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	121	Target Neighborhood Hits	111	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

KBTB9_HUMAN
NC score	0.059431 (rank : 56)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	24
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KLH12_MOUSE
NC score	0.059077 (rank : 57)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BZM0, Q8K225	Gene names	Klhl12, C3ip1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

KLH12_HUMAN
NC score	0.058955 (rank : 58)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q53G59, Q9HBX5	Gene names	KLHL12, C3IP1
Domain Architecture	No domain graphic available
Description	Kelch-like protein 12 (CUL3-interacting protein 1).

KBTB9_MOUSE
NC score	0.058851 (rank : 59)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	121	Target Neighborhood Hits	197	Shared Neighborhood Hits	23
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KLH10_HUMAN
NC score	0.058701 (rank : 60)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	23
SwissProt Accessions	Q6JEL2, Q6NW28, Q96MC0	Gene names	KLHL10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KLHL1_HUMAN
NC score	0.058153 (rank : 61)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	121	Target Neighborhood Hits	195	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NR64, Q5VZ64, Q9H4X4, Q9NR65, Q9P238	Gene names	KLHL1, KIAA1490
Domain Architecture
Description	Kelch-like protein 1.

KBTBA_HUMAN
NC score	0.056145 (rank : 62)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	121	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

KLH10_MOUSE
NC score	0.055866 (rank : 63)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D5V2, Q8BVM3, Q9DA07	Gene names	Klhl10
Domain Architecture	No domain graphic available
Description	Kelch-like protein 10.

KEAP1_HUMAN
NC score	0.055773 (rank : 64)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	121	Target Neighborhood Hits	181	Shared Neighborhood Hits	23
SwissProt Accessions	Q14145, Q6LEP0	Gene names	KEAP1, KIAA0132, KLHL19
Domain Architecture	No domain graphic available
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (Kelch-like protein 19).

KLH26_HUMAN
NC score	0.055720 (rank : 65)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q53HC5, Q8TAP0, Q9NUX3	Gene names	KLHL26
Domain Architecture	No domain graphic available
Description	Kelch-like protein 26.

KLHL5_HUMAN
NC score	0.055440 (rank : 66)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PQ7, Q86XW0, Q9NUK3, Q9NV27, Q9NVA9, Q9Y2X2	Gene names	KLHL5
Domain Architecture
Description	Kelch-like protein 5.

KEAP1_MOUSE
NC score	0.054211 (rank : 67)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	121	Target Neighborhood Hits	182	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

KLHL1_MOUSE
NC score	0.054123 (rank : 68)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	121	Target Neighborhood Hits	193	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

MDC1_HUMAN
NC score	0.054012 (rank : 69)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	121	Target Neighborhood Hits	1446	Shared Neighborhood Hits	29
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

GAN_HUMAN
NC score	0.053116 (rank : 70)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	121	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2C0	Gene names	GAN, GAN1, KLHL16
Domain Architecture
Description	Gigaxonin (Kelch-like protein 16).

BTBD5_HUMAN
NC score	0.052741 (rank : 71)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

KLHL7_MOUSE
NC score	0.050944 (rank : 72)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	121	Target Neighborhood Hits	179	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BUL5, Q9CZP4	Gene names	Klhl7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

KLHL7_HUMAN
NC score	0.050356 (rank : 73)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	121	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IXQ5, Q9BQF8	Gene names	KLHL7
Domain Architecture	No domain graphic available
Description	Kelch-like protein 7.

BAG3_HUMAN
NC score	0.048268 (rank : 74)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	121	Target Neighborhood Hits	314	Shared Neighborhood Hits	19
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

FBX2_MOUSE
NC score	0.047410 (rank : 75)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	121	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q80UW2, Q8R0D2	Gene names	Fbxo2, Fbx2
Domain Architecture	No domain graphic available
Description	F-box only protein 2.

SPT5H_MOUSE
NC score	0.045397 (rank : 76)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	121	Target Neighborhood Hits	437	Shared Neighborhood Hits	23
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.044337 (rank : 77)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	121	Target Neighborhood Hits	436	Shared Neighborhood Hits	20
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

MUC1_MOUSE
NC score	0.044147 (rank : 78)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	121	Target Neighborhood Hits	388	Shared Neighborhood Hits	21
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NACAM_MOUSE
NC score	0.043884 (rank : 79)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	121	Target Neighborhood Hits	1866	Shared Neighborhood Hits	39
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM2_MOUSE
NC score	0.043033 (rank : 80)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	121	Target Neighborhood Hits	1470	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FBX2_HUMAN
NC score	0.042980 (rank : 81)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UK22, Q6FGJ7, Q8TB29, Q9UKC6	Gene names	FBXO2, FBX2
Domain Architecture
Description	F-box only protein 2.

CI082_MOUSE
NC score	0.038209 (rank : 82)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDY9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82 homolog.

TNNT1_HUMAN
NC score	0.037344 (rank : 83)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	121	Target Neighborhood Hits	211	Shared Neighborhood Hits	6
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

RUNX2_MOUSE
NC score	0.036661 (rank : 84)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	121	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

CU056_HUMAN
NC score	0.035095 (rank : 85)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	121	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0A9, Q9NSE5	Gene names	C21orf56
Domain Architecture	No domain graphic available
Description	Putative protein C21orf56.

BAG4_MOUSE
NC score	0.034215 (rank : 86)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	121	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CI61, Q3TRL9, Q91VT5, Q9CWG2	Gene names	Bag4, Sodd
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

RUNX2_HUMAN
NC score	0.033707 (rank : 87)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	121	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

MAML1_HUMAN
NC score	0.033612 (rank : 88)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	121	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PCLO_MOUSE
NC score	0.031966 (rank : 89)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	121	Target Neighborhood Hits	2275	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NUPL2_MOUSE
NC score	0.031211 (rank : 90)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

BSN_HUMAN
NC score	0.030620 (rank : 91)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	121	Target Neighborhood Hits	1537	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CSF1_MOUSE
NC score	0.029877 (rank : 92)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	121	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

PCLO_HUMAN
NC score	0.029713 (rank : 93)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	121	Target Neighborhood Hits	2046	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHF12_MOUSE
NC score	0.029138 (rank : 94)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	121	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TCP10_HUMAN
NC score	0.029117 (rank : 95)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	121	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

MN1_HUMAN
NC score	0.028798 (rank : 96)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

FBX27_HUMAN
NC score	0.027444 (rank : 97)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NI29, Q96C87	Gene names	FBXO27, FBG5, FBX27
Domain Architecture
Description	F-box only protein 27 (F-box/G-domain protein 5).

BRCA2_HUMAN
NC score	0.027093 (rank : 98)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	121	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

PAPOG_MOUSE
NC score	0.027072 (rank : 99)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	121	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

NFH_MOUSE
NC score	0.025240 (rank : 100)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	121	Target Neighborhood Hits	2247	Shared Neighborhood Hits	41
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PAPOG_HUMAN
NC score	0.024984 (rank : 101)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BWT3, Q969N1, Q9H8L2, Q9HAD0	Gene names	PAPOLG, PAP2, PAPG
Domain Architecture
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme) (Neo- poly(A) polymerase) (Neo-PAP).

MNAB_HUMAN
NC score	0.023941 (rank : 102)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

CSPG3_MOUSE
NC score	0.023333 (rank : 103)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	121	Target Neighborhood Hits	657	Shared Neighborhood Hits	17
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

IRS1_MOUSE
NC score	0.022608 (rank : 104)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	121	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

FBXL7_HUMAN
NC score	0.022521 (rank : 105)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	121	Target Neighborhood Hits	91	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

ARI1A_HUMAN
NC score	0.022119 (rank : 106)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	121	Target Neighborhood Hits	787	Shared Neighborhood Hits	26
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

PRRT3_MOUSE
NC score	0.021454 (rank : 107)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	121	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ZC3H3_HUMAN
NC score	0.021115 (rank : 108)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	121	Target Neighborhood Hits	159	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

MAGC1_HUMAN
NC score	0.020945 (rank : 109)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	121	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MSPD3_HUMAN
NC score	0.020942 (rank : 110)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	121	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	O75425, O75423, O75424	Gene names	MOSPD3
Domain Architecture	No domain graphic available
Description	Motile sperm domain-containing protein 3.

CPSF6_MOUSE
NC score	0.020564 (rank : 111)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	121	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

RIN2_HUMAN
NC score	0.018244 (rank : 112)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	121	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

SEPT9_HUMAN
NC score	0.018215 (rank : 113)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	121	Target Neighborhood Hits	706	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ZNT1_HUMAN
NC score	0.017966 (rank : 114)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	121	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6M5, Q9BZF6	Gene names	SLC30A1, ZNT1
Domain Architecture
Description	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1).

PUM1_HUMAN
NC score	0.016974 (rank : 115)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	121	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q14671, Q5VXY7, Q9HAN1	Gene names	PUM1, KIAA0099, PUMH1
Domain Architecture
Description	Pumilio homolog 1 (Pumilio-1) (HsPUM).

PUM1_MOUSE
NC score	0.016965 (rank : 116)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	121	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q80U78, Q80X96, Q80YU8, Q8BPV7, Q9EPU6	Gene names	Pum1, Kiaa0099
Domain Architecture
Description	Pumilio homolog 1.

RBNS5_HUMAN
NC score	0.015797 (rank : 117)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	121	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

PRGC2_HUMAN
NC score	0.014357 (rank : 118)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	121	Target Neighborhood Hits	272	Shared Neighborhood Hits	10
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

FOXL1_HUMAN
NC score	0.014336 (rank : 119)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	121	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

BRD2_HUMAN
NC score	0.013966 (rank : 120)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	121	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

SYN3_HUMAN
NC score	0.013966 (rank : 121)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	121	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

XKR7_HUMAN
NC score	0.011265 (rank : 122)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	121	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

MCA1_HUMAN
NC score	0.010822 (rank : 123)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q12904, Q6FG28, Q96CQ9	Gene names	SCYE1, EMAP2
Domain Architecture
Description	Multisynthetase complex auxiliary component p43 [Contains: Endothelial monocyte-activating polypeptide 2 (EMAP-II) (Small inducible cytokine subfamily E member 1)].

TLN1_MOUSE
NC score	0.010693 (rank : 124)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	121	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

SSPO_MOUSE
NC score	0.010652 (rank : 125)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	121	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ANK2_HUMAN
NC score	0.010614 (rank : 126)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	121	Target Neighborhood Hits	1615	Shared Neighborhood Hits	36
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TLN1_HUMAN
NC score	0.010545 (rank : 127)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	121	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

ZMYM1_HUMAN
NC score	0.010309 (rank : 128)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	121	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SVZ6, Q7Z3Q4	Gene names	ZMYM1
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 1.

JHD2B_HUMAN
NC score	0.010129 (rank : 129)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	121	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

SPEG_MOUSE
NC score	0.010122 (rank : 130)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	121	Target Neighborhood Hits	1959	Shared Neighborhood Hits	41
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

EPAS1_HUMAN
NC score	0.009538 (rank : 131)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	121	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

DLX4_MOUSE
NC score	0.009469 (rank : 132)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	121	Target Neighborhood Hits	352	Shared Neighborhood Hits	7
SwissProt Accessions	P70436, Q3UM51, Q8R4I3	Gene names	Dlx4, Dlx7
Domain Architecture
Description	Homeobox protein DLX-4 (DLX-7).

ANR43_MOUSE
NC score	0.009256 (rank : 133)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	121	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

MTMR3_HUMAN
NC score	0.009017 (rank : 134)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	121	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q13615, Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3	Gene names	MTMR3, KIAA0371, ZFYVE10
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Zinc finger FYVE domain-containing protein 10).

JIP3_MOUSE
NC score	0.007219 (rank : 135)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	121	Target Neighborhood Hits	759	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

NKX61_MOUSE
NC score	0.006935 (rank : 136)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	121	Target Neighborhood Hits	439	Shared Neighborhood Hits	10
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

DDX51_HUMAN
NC score	0.006837 (rank : 137)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	121	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

PHLB2_MOUSE
NC score	0.006435 (rank : 138)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	121	Target Neighborhood Hits	1016	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

HME2_HUMAN
NC score	0.006239 (rank : 139)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	121	Target Neighborhood Hits	355	Shared Neighborhood Hits	6
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

INVS_HUMAN
NC score	0.005802 (rank : 140)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	121	Target Neighborhood Hits	455	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

RU17_MOUSE
NC score	0.005500 (rank : 141)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

PCNT_MOUSE
NC score	0.004972 (rank : 142)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	121	Target Neighborhood Hits	1207	Shared Neighborhood Hits	13
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

OBSCN_HUMAN
NC score	0.004691 (rank : 143)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	121	Target Neighborhood Hits	1931	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

EVX2_HUMAN
NC score	0.004513 (rank : 144)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	121	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q03828	Gene names	EVX2
Domain Architecture
Description	Homeobox even-skipped homolog protein 2 (EVX-2).

PP16A_HUMAN
NC score	0.004330 (rank : 145)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	121	Target Neighborhood Hits	340	Shared Neighborhood Hits	6
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ARHGC_MOUSE
NC score	0.004065 (rank : 146)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	121	Target Neighborhood Hits	344	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

ZBT16_HUMAN
NC score	0.003164 (rank : 147)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	121	Target Neighborhood Hits	1010	Shared Neighborhood Hits	20
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

SALL3_HUMAN
NC score	0.002328 (rank : 148)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	121	Target Neighborhood Hits	1066	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

BRSK1_HUMAN
NC score	0.002216 (rank : 149)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	121	Target Neighborhood Hits	942	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

M3K12_HUMAN
NC score	0.000792 (rank : 150)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	121	Target Neighborhood Hits	940	Shared Neighborhood Hits	10
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

PKN1_HUMAN
NC score	0.000559 (rank : 151)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	121	Target Neighborhood Hits	886	Shared Neighborhood Hits	12
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

M3K1_MOUSE
NC score	0.000296 (rank : 152)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	121	Target Neighborhood Hits	952	Shared Neighborhood Hits	12
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

SP4_HUMAN
NC score	-0.001148 (rank : 153)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	121	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).