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Network neighborhood for query Sequence : FBSP1_MOUSE

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FBSP1_MOUSE
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FBSP1_MOUSE
θ value	5.77539e-148 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

SPSB2_HUMAN
θ value	1.51715e-39 (rank : 2)	NC score	0.906510 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q99619	Gene names	SPSB2, GRCC9, SSB2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SPSB2_MOUSE
θ value	3.16345e-37 (rank : 3)	NC score	0.896148 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SSB4_MOUSE
θ value	5.39604e-37 (rank : 4)	NC score	0.891724 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R5B6, Q8BJI9, Q8VHS8	Gene names	Spsb4, Ssb4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SSB4_HUMAN
θ value	1.20211e-36 (rank : 5)	NC score	0.889178 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SSB1_HUMAN
θ value	7.29293e-34 (rank : 6)	NC score	0.894111 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q96BD6, Q59FA1, Q5TIH9, Q9BRY9, Q9H6C5	Gene names	SPSB1, SSB1
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 1 (SSB-1).

SSB1_MOUSE
θ value	7.29293e-34 (rank : 7)	NC score	0.890413 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D5L7, Q5FWI0, Q8BJA4	Gene names	Spsb1, Ssb1
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 1 (SSB-1).

FBX10_HUMAN
θ value	0.00298849 (rank : 8)	NC score	0.120630 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

TRIM9_MOUSE
θ value	0.0431538 (rank : 9)	NC score	0.151758 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

FBX42_HUMAN
θ value	0.0563607 (rank : 10)	NC score	0.085483 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBX42_MOUSE
θ value	0.0563607 (rank : 11)	NC score	0.086065 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBW1A_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.033944 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	329	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

TRIM9_HUMAN
θ value	0.163984 (rank : 13)	NC score	0.131325 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	294	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

FBW12_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.087888 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FBXL7_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.061432 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	91	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

SKP2_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.083858 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

TRI18_HUMAN
θ value	0.21417 (rank : 17)	NC score	0.044908 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

FBXW4_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.053935 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

PHF2_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.028728 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

SKP2_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.076681 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	79	Shared Neighborhood Hits	17
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

TRI18_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.043363 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

FBX16_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.051358 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FXL21_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.039200 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

TRI14_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.040228 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	143	Shared Neighborhood Hits	9
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

FBW1B_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.027321 (rank : 41)
Query Neighborhood Hits	39	Target Neighborhood Hits	327	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBX22_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.028300 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q78JE5	Gene names	Fbxo22, Fbx22
Domain Architecture	No domain graphic available
Description	F-box only protein 22.

FBX9_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.042831 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UK97, O75986, Q6PKH7, Q9NT57, Q9Y593	Gene names	FBXO9, FBX9, VCIA1
Domain Architecture	No domain graphic available
Description	F-box only protein 9 (NY-REN-57 antigen) (Cross-immune reaction antigen 1).

FBX9_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.043007 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BK06, Q8VDY6, Q9D349, Q9JJC5	Gene names	Fbxo9
Domain Architecture	No domain graphic available
Description	F-box only protein 9.

FBXW4_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.045677 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	205	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

FBX33_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.047699 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBX31_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.035916 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

FBXW7_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.025137 (rank : 43)
Query Neighborhood Hits	39	Target Neighborhood Hits	433	Shared Neighborhood Hits	19
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXW7_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.025152 (rank : 42)
Query Neighborhood Hits	39	Target Neighborhood Hits	365	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW8_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.039462 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	192	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FXL21_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.036429 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

JHD1A_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.030091 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

FBXL8_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.021453 (rank : 44)
Query Neighborhood Hits	39	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).

JHD1A_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.029206 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

TRI14_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.053094 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

ASB1_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.065704 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.074715 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

FBX11_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.051642 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	72	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

RN123_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.061304 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.061167 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

Hits sorted by NC score

FBSP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.77539e-148 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K3B1, Q5M7B1	Gene names	Fbxo45
Domain Architecture	No domain graphic available
Description	F-box/SPRY-domain protein 1 (F-box only protein 45).

SPSB2_HUMAN
NC score	0.906510 (rank : 2)	θ value	1.51715e-39 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q99619	Gene names	SPSB2, GRCC9, SSB2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SPSB2_MOUSE
NC score	0.896148 (rank : 3)	θ value	3.16345e-37 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	11
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SSB1_HUMAN
NC score	0.894111 (rank : 4)	θ value	7.29293e-34 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q96BD6, Q59FA1, Q5TIH9, Q9BRY9, Q9H6C5	Gene names	SPSB1, SSB1
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 1 (SSB-1).

SSB4_MOUSE
NC score	0.891724 (rank : 5)	θ value	5.39604e-37 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R5B6, Q8BJI9, Q8VHS8	Gene names	Spsb4, Ssb4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

SSB1_MOUSE
NC score	0.890413 (rank : 6)	θ value	7.29293e-34 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D5L7, Q5FWI0, Q8BJA4	Gene names	Spsb1, Ssb1
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 1 (SSB-1).

SSB4_HUMAN
NC score	0.889178 (rank : 7)	θ value	1.20211e-36 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q96A44	Gene names	SPSB4, SSB4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 4 (SSB-4).

TRIM9_MOUSE
NC score	0.151758 (rank : 8)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRIM9_HUMAN
NC score	0.131325 (rank : 9)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	294	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

FBX10_HUMAN
NC score	0.120630 (rank : 10)	θ value	0.00298849 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UK96, Q5JRT8, Q9UKC3	Gene names	FBXO10, FBX10
Domain Architecture	No domain graphic available
Description	F-box only protein 10.

FBW12_HUMAN
NC score	0.087888 (rank : 11)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	Q6X9E4	Gene names	FBXW12, FBW12, FBXO12, FBXO35
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 12 (F-box and WD-40 domain protein 12) (F-box only protein 35).

FBX42_MOUSE
NC score	0.086065 (rank : 12)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PDJ6, Q8CE76, Q99KY2	Gene names	Fbxo42
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

FBX42_HUMAN
NC score	0.085483 (rank : 13)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3S6, Q5TEU8, Q86XI0, Q8N3N4, Q8N5F8, Q9BRM0, Q9P2L4	Gene names	FBXO42, FBX42, KIAA1332
Domain Architecture	No domain graphic available
Description	F-box only protein 42.

SKP2_MOUSE
NC score	0.083858 (rank : 14)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

SKP2_HUMAN
NC score	0.076681 (rank : 15)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	79	Shared Neighborhood Hits	17
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

ASB1_MOUSE
NC score	0.074715 (rank : 16)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	39	Target Neighborhood Hits	292	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_HUMAN
NC score	0.065704 (rank : 17)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

FBXL7_HUMAN
NC score	0.061432 (rank : 18)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	91	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

RN123_HUMAN
NC score	0.061304 (rank : 19)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	39	Target Neighborhood Hits	175	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
NC score	0.061167 (rank : 20)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	39	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

FBXW4_HUMAN
NC score	0.053935 (rank : 21)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	209	Shared Neighborhood Hits	12
SwissProt Accessions	P57775, Q5SVS1, Q96IM6	Gene names	FBXW4, FBW4, SHFM3
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Dactylin).

TRI14_MOUSE
NC score	0.053094 (rank : 22)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

FBX11_HUMAN
NC score	0.051642 (rank : 23)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	39	Target Neighborhood Hits	72	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XK2, Q8IXG3, Q96E90, Q9H6V8, Q9H9L1, Q9NR14, Q9UFK1, Q9UHI1, Q9UKC2	Gene names	FBXO11, FBX11, VIT1
Domain Architecture
Description	F-box only protein 11 (Vitiligo-associated protein VIT-1).

FBX16_HUMAN
NC score	0.051358 (rank : 24)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IX29, Q3T1B4	Gene names	FBXO16, FBX16
Domain Architecture
Description	F-box only protein 16.

FBX33_HUMAN
NC score	0.047699 (rank : 25)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z6M2, Q6PIR2, Q86TR2, Q86YE0	Gene names	FBXO33, FBX33
Domain Architecture	No domain graphic available
Description	F-box only protein 33.

FBXW4_MOUSE
NC score	0.045677 (rank : 26)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	205	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JMJ2, Q9QXW3	Gene names	Fbxw4, Fbw4
Domain Architecture
Description	F-box/WD repeat protein 4 (F-box and WD-40 domain protein 4) (Hagoromo protein).

TRI18_HUMAN
NC score	0.044908 (rank : 27)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
NC score	0.043363 (rank : 28)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

FBX9_MOUSE
NC score	0.043007 (rank : 29)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BK06, Q8VDY6, Q9D349, Q9JJC5	Gene names	Fbxo9
Domain Architecture	No domain graphic available
Description	F-box only protein 9.

FBX9_HUMAN
NC score	0.042831 (rank : 30)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UK97, O75986, Q6PKH7, Q9NT57, Q9Y593	Gene names	FBXO9, FBX9, VCIA1
Domain Architecture	No domain graphic available
Description	F-box only protein 9 (NY-REN-57 antigen) (Cross-immune reaction antigen 1).

TRI14_HUMAN
NC score	0.040228 (rank : 31)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	143	Shared Neighborhood Hits	9
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

FBXW8_HUMAN
NC score	0.039462 (rank : 32)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	192	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N3Y1, Q9UK95	Gene names	FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
Domain Architecture
Description	F-box/WD repeat protein 8 (F-box and WD-40 domain protein 8) (F-box only protein 29).

FXL21_HUMAN
NC score	0.039200 (rank : 33)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKT6	Gene names	FBXL21, FBL21, FBL3, FBXL3B
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FXL21_MOUSE
NC score	0.036429 (rank : 34)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	49	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BFZ4, Q8BIJ8, Q8BIW5	Gene names	Fbxl21, Fbl21, Fbxl3b
Domain Architecture
Description	F-box/LRR-repeat protein 21 (F-box and leucine-rich repeat protein 21) (F-box/LRR-repeat protein 3B) (F-box and leucine-rich repeat protein 3B).

FBX31_HUMAN
NC score	0.035916 (rank : 35)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

FBW1A_HUMAN
NC score	0.033944 (rank : 36)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	329	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

JHD1A_MOUSE
NC score	0.030091 (rank : 37)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1A_HUMAN
NC score	0.029206 (rank : 38)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

PHF2_MOUSE
NC score	0.028728 (rank : 39)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

FBX22_MOUSE
NC score	0.028300 (rank : 40)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q78JE5	Gene names	Fbxo22, Fbx22
Domain Architecture	No domain graphic available
Description	F-box only protein 22.

FBW1B_HUMAN
NC score	0.027321 (rank : 41)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	327	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKB1, Q9P2S8, Q9P2S9, Q9Y4C6	Gene names	FBXW11, BTRCP2, FBW1B, FBXW1B, KIAA0696
Domain Architecture
Description	F-box/WD repeat protein 11 (F-box/WD repeat protein 1B) (F-box and WD repeats protein beta-TrCP2).

FBXW7_MOUSE
NC score	0.025152 (rank : 42)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	365	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VBV4, Q8CCS5, Q8VHP4	Gene names	Fbxw7, Fbw7, Fbwd6, Fbxw6
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10).

FBXW7_HUMAN
NC score	0.025137 (rank : 43)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	433	Shared Neighborhood Hits	19
SwissProt Accessions	Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6	Gene names	FBXW7, FBW7, FBX30, SEL10
Domain Architecture
Description	F-box/WD repeat protein 7 (F-box and WD-40 domain protein 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10).

FBXL8_HUMAN
NC score	0.021453 (rank : 44)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q96CD0, Q9NUM0	Gene names	FBXL8, FBL8
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) (F-box protein FBL8).