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Network neighborhood for query Sequence : EDAR_MOUSE

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EDAR_MOUSE
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EDAR_HUMAN
θ value	0 (rank : 1)	NC score	0.985125 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

TNR19_MOUSE
θ value	1.74796e-11 (rank : 3)	NC score	0.524115 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_HUMAN
θ value	6.64225e-11 (rank : 4)	NC score	0.513526 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	89	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_MOUSE
θ value	1.25267e-09 (rank : 5)	NC score	0.521199 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_HUMAN
θ value	1.63604e-09 (rank : 6)	NC score	0.515668 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_HUMAN
θ value	3.77169e-06 (rank : 7)	NC score	0.330734 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR4_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.281440 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR9_HUMAN
θ value	0.0113563 (rank : 9)	NC score	0.225246 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR25_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.193315 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	172	Shared Neighborhood Hits	30
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR1B_HUMAN
θ value	0.0252991 (rank : 11)	NC score	0.205014 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	127	Shared Neighborhood Hits	30
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR3_MOUSE
θ value	0.0330416 (rank : 12)	NC score	0.216856 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	113	Shared Neighborhood Hits	30
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.187347 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR1B_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.196655 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	123	Shared Neighborhood Hits	30
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR6_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.171371 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	99	Shared Neighborhood Hits	26
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR18_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.171500 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR5_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.204098 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

IF2B_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.088892 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

MEGF9_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.053449 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	557	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TNR6B_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.196186 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

MUC5B_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.040631 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	1020	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TNR4_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.207820 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	152	Shared Neighborhood Hits	30
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

NEUM_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.068726 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

TNR16_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.154427 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	183	Shared Neighborhood Hits	29
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.171021 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

USH2A_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.034935 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	626	Shared Neighborhood Hits	28
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

SRCA_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.028644 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TNR9_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.215465 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR18_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.146203 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

K2027_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.035629 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MEGF8_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.058503 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	528	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

DDX24_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.021335 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

LMO3_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.039192 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAP4, Q8N974, Q9UDD5	Gene names	LMO3, RBTN3, RHOM3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1) (Rhombotin-3).

LMO3_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.039192 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BZL8	Gene names	Lmo3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1).

POT14_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.012745 (rank : 80)
Query Neighborhood Hits	66	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

RBTN1_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.039223 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	P25800, Q4VBC5	Gene names	LMO1, RBTN1, RHOM1, TTG1
Domain Architecture
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (T-cell translocation protein 1) (LIM-only protein 1).

RBTN1_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.039199 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q924W9	Gene names	Lmo1, Rbtn1, Rhom1, Ttg1
Domain Architecture	No domain graphic available
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM-only protein 1).

TNR14_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.206479 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	149	Shared Neighborhood Hits	32
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TS1R1_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.023718 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

SERC1_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.037516 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRX5, O75655, Q7Z2F5, Q8TAG1, Q9NTH8, Q9ULG7	Gene names	SERINC1, KIAA1253, TDE1L, TDE2
Domain Architecture
Description	Serine incorporator 1 (Tumor differentially expressed protein 2) (Tumor differentially expressed 1 protein-like).

CER1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.031766 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

CREL1_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.035254 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DNL1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.021721 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

FRAS1_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.046882 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	747	Shared Neighborhood Hits	31
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RGS3_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.008707 (rank : 83)
Query Neighborhood Hits	66	Target Neighborhood Hits	1621	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BRPF1_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.011851 (rank : 81)
Query Neighborhood Hits	66	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

LAMA1_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.037147 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	838	Shared Neighborhood Hits	33
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

PGBM_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.021465 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	1073	Shared Neighborhood Hits	30
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SCUB3_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.028183 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	442	Shared Neighborhood Hits	30
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SERC1_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.033383 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZI8, Q3UZ93	Gene names	Serinc1, Aigp2, Tde1l, Tde2, Tms2
Domain Architecture
Description	Serine incorporator 1 (Tumor differentially expressed protein 2) (Tumor differentially expressed 1 protein-like) (Membrane protein TMS- 2) (Axotomy-induced glyco/Golgi protein 2).

CREL1_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.028293 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	524	Shared Neighborhood Hits	16
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MEGF8_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.046400 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	520	Shared Neighborhood Hits	24
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SSPO_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.027110 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	800	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TMM10_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.061387 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M750, Q6P903	Gene names	Tmem10
Domain Architecture	No domain graphic available
Description	Transmembrane protein TMP10.

CC020_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.017729 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDN1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C3orf20 homolog.

EPHA4_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.001625 (rank : 86)
Query Neighborhood Hits	66	Target Neighborhood Hits	982	Shared Neighborhood Hits	11
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

FAT2_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.005359 (rank : 85)
Query Neighborhood Hits	66	Target Neighborhood Hits	507	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

SCUB3_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.026803 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	428	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CM031_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.015429 (rank : 77)
Query Neighborhood Hits	66	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IV20, Q8N8X5	Gene names	C13orf31
Domain Architecture
Description	UPF0124 protein C13orf31.

DAXX_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.013834 (rank : 78)
Query Neighborhood Hits	66	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

EPHA4_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.001576 (rank : 87)
Query Neighborhood Hits	66	Target Neighborhood Hits	975	Shared Neighborhood Hits	11
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

ERRFI_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.013489 (rank : 79)
Query Neighborhood Hits	66	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

IWS1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.016628 (rank : 76)
Query Neighborhood Hits	66	Target Neighborhood Hits	1241	Shared Neighborhood Hits	11
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NGEF_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.006484 (rank : 84)
Query Neighborhood Hits	66	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

SUHW4_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.001329 (rank : 88)
Query Neighborhood Hits	66	Target Neighborhood Hits	737	Shared Neighborhood Hits	2
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TCF20_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.011201 (rank : 82)
Query Neighborhood Hits	66	Target Neighborhood Hits	396	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TNR11_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.142744 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.160009 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR1A_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.126342 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	121	Shared Neighborhood Hits	25
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1A_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.138701 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR21_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.105008 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.121812 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR22_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.113652 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	97	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.111657 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR26_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.108684 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.180045 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR6_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.099845 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.138420 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.132262 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.082121 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.065698 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	208	Shared Neighborhood Hits	25
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR10A_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.052362 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.052785 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.054937 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10C_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.059720 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR11B_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.134848 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.146226 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR19L_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.189763 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	85	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

Hits sorted by NC score

EDAR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

EDAR_HUMAN
NC score	0.985125 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

TNR19_MOUSE
NC score	0.524115 (rank : 3)	θ value	1.74796e-11 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	100	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_MOUSE
NC score	0.521199 (rank : 4)	θ value	1.25267e-09 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_HUMAN
NC score	0.515668 (rank : 5)	θ value	1.63604e-09 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_HUMAN
NC score	0.513526 (rank : 6)	θ value	6.64225e-11 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	89	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TR19L_HUMAN
NC score	0.330734 (rank : 7)	θ value	3.77169e-06 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR4_MOUSE
NC score	0.281440 (rank : 8)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR9_HUMAN
NC score	0.225246 (rank : 9)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	166	Shared Neighborhood Hits	31
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR3_MOUSE
NC score	0.216856 (rank : 10)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	113	Shared Neighborhood Hits	30
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR9_MOUSE
NC score	0.215465 (rank : 11)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR4_HUMAN
NC score	0.207820 (rank : 12)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	152	Shared Neighborhood Hits	30
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR14_HUMAN
NC score	0.206479 (rank : 13)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	149	Shared Neighborhood Hits	32
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR1B_HUMAN
NC score	0.205014 (rank : 14)	θ value	0.0252991 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	127	Shared Neighborhood Hits	30
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR5_HUMAN
NC score	0.204098 (rank : 15)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR1B_MOUSE
NC score	0.196655 (rank : 16)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	123	Shared Neighborhood Hits	30
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR6B_HUMAN
NC score	0.196186 (rank : 17)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR25_HUMAN
NC score	0.193315 (rank : 18)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	172	Shared Neighborhood Hits	30
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TR19L_MOUSE
NC score	0.189763 (rank : 19)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	66	Target Neighborhood Hits	85	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TNR5_MOUSE
NC score	0.187347 (rank : 20)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR3_HUMAN
NC score	0.180045 (rank : 21)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	66	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR18_HUMAN
NC score	0.171500 (rank : 22)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR6_MOUSE
NC score	0.171371 (rank : 23)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	99	Shared Neighborhood Hits	26
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR16_MOUSE
NC score	0.171021 (rank : 24)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR11_MOUSE
NC score	0.160009 (rank : 25)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR16_HUMAN
NC score	0.154427 (rank : 26)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	183	Shared Neighborhood Hits	29
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TR11B_MOUSE
NC score	0.146226 (rank : 27)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	66	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR18_MOUSE
NC score	0.146203 (rank : 28)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR11_HUMAN
NC score	0.142744 (rank : 29)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR1A_MOUSE
NC score	0.138701 (rank : 30)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR7_HUMAN
NC score	0.138420 (rank : 31)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	66	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TR11B_HUMAN
NC score	0.134848 (rank : 32)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR7_MOUSE
NC score	0.132262 (rank : 33)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	66	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR1A_HUMAN
NC score	0.126342 (rank : 34)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	121	Shared Neighborhood Hits	25
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR21_MOUSE
NC score	0.121812 (rank : 35)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	108	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR22_MOUSE
NC score	0.113652 (rank : 36)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	97	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
NC score	0.111657 (rank : 37)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR26_MOUSE
NC score	0.108684 (rank : 38)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR21_HUMAN
NC score	0.105008 (rank : 39)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR6_HUMAN
NC score	0.099845 (rank : 40)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	66	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

IF2B_MOUSE
NC score	0.088892 (rank : 41)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

TNR8_HUMAN
NC score	0.082121 (rank : 42)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	66	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

NEUM_MOUSE
NC score	0.068726 (rank : 43)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

TNR8_MOUSE
NC score	0.065698 (rank : 44)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	66	Target Neighborhood Hits	208	Shared Neighborhood Hits	25
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TMM10_MOUSE
NC score	0.061387 (rank : 45)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M750, Q6P903	Gene names	Tmem10
Domain Architecture	No domain graphic available
Description	Transmembrane protein TMP10.

TR10C_HUMAN
NC score	0.059720 (rank : 46)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	66	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

MEGF8_HUMAN
NC score	0.058503 (rank : 47)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	528	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TR10B_MOUSE
NC score	0.054937 (rank : 48)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

MEGF9_HUMAN
NC score	0.053449 (rank : 49)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	557	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TR10B_HUMAN
NC score	0.052785 (rank : 50)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	66	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10A_HUMAN
NC score	0.052362 (rank : 51)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	66	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

FRAS1_MOUSE
NC score	0.046882 (rank : 52)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	747	Shared Neighborhood Hits	31
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF8_MOUSE
NC score	0.046400 (rank : 53)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	520	Shared Neighborhood Hits	24
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MUC5B_HUMAN
NC score	0.040631 (rank : 54)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	1020	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

RBTN1_HUMAN
NC score	0.039223 (rank : 55)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	P25800, Q4VBC5	Gene names	LMO1, RBTN1, RHOM1, TTG1
Domain Architecture
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (T-cell translocation protein 1) (LIM-only protein 1).

RBTN1_MOUSE
NC score	0.039199 (rank : 56)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q924W9	Gene names	Lmo1, Rbtn1, Rhom1, Ttg1
Domain Architecture	No domain graphic available
Description	Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM-only protein 1).

LMO3_HUMAN
NC score	0.039192 (rank : 57)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAP4, Q8N974, Q9UDD5	Gene names	LMO3, RBTN3, RHOM3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1) (Rhombotin-3).

LMO3_MOUSE
NC score	0.039192 (rank : 58)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BZL8	Gene names	Lmo3
Domain Architecture
Description	LIM-only protein 3 (Neuronal-specific transcription factor DAT1).

SERC1_HUMAN
NC score	0.037516 (rank : 59)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRX5, O75655, Q7Z2F5, Q8TAG1, Q9NTH8, Q9ULG7	Gene names	SERINC1, KIAA1253, TDE1L, TDE2
Domain Architecture
Description	Serine incorporator 1 (Tumor differentially expressed protein 2) (Tumor differentially expressed 1 protein-like).

LAMA1_MOUSE
NC score	0.037147 (rank : 60)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	838	Shared Neighborhood Hits	33
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

K2027_MOUSE
NC score	0.035629 (rank : 61)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

CREL1_HUMAN
NC score	0.035254 (rank : 62)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

USH2A_MOUSE
NC score	0.034935 (rank : 63)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	626	Shared Neighborhood Hits	28
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

SERC1_MOUSE
NC score	0.033383 (rank : 64)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZI8, Q3UZ93	Gene names	Serinc1, Aigp2, Tde1l, Tde2, Tms2
Domain Architecture
Description	Serine incorporator 1 (Tumor differentially expressed protein 2) (Tumor differentially expressed 1 protein-like) (Membrane protein TMS- 2) (Axotomy-induced glyco/Golgi protein 2).

CER1_HUMAN
NC score	0.031766 (rank : 65)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	O95813, Q6ISJ1, Q6ISJ6, Q6ISQ2, Q6ISS1	Gene names	CER1
Domain Architecture	No domain graphic available
Description	Cerberus precursor (Cerberus-related protein).

SRCA_MOUSE
NC score	0.028644 (rank : 66)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

CREL1_MOUSE
NC score	0.028293 (rank : 67)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	524	Shared Neighborhood Hits	16
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SCUB3_MOUSE
NC score	0.028183 (rank : 68)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	442	Shared Neighborhood Hits	30
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SSPO_MOUSE
NC score	0.027110 (rank : 69)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	800	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SCUB3_HUMAN
NC score	0.026803 (rank : 70)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	428	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TS1R1_HUMAN
NC score	0.023718 (rank : 71)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

DNL1_HUMAN
NC score	0.021721 (rank : 72)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

PGBM_MOUSE
NC score	0.021465 (rank : 73)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	1073	Shared Neighborhood Hits	30
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

DDX24_MOUSE
NC score	0.021335 (rank : 74)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	147	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

CC020_MOUSE
NC score	0.017729 (rank : 75)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDN1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C3orf20 homolog.

IWS1_HUMAN
NC score	0.016628 (rank : 76)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	1241	Shared Neighborhood Hits	11
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CM031_HUMAN
NC score	0.015429 (rank : 77)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IV20, Q8N8X5	Gene names	C13orf31
Domain Architecture
Description	UPF0124 protein C13orf31.

DAXX_MOUSE
NC score	0.013834 (rank : 78)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

ERRFI_HUMAN
NC score	0.013489 (rank : 79)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

POT14_HUMAN
NC score	0.012745 (rank : 80)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

BRPF1_HUMAN
NC score	0.011851 (rank : 81)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

TCF20_MOUSE
NC score	0.011201 (rank : 82)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	396	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RGS3_MOUSE
NC score	0.008707 (rank : 83)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	1621	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NGEF_HUMAN
NC score	0.006484 (rank : 84)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5V2, Q53QQ4, Q53ST7, Q6GMQ5, Q9NQD6	Gene names	NGEF
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

FAT2_HUMAN
NC score	0.005359 (rank : 85)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	507	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

EPHA4_MOUSE
NC score	0.001625 (rank : 86)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	982	Shared Neighborhood Hits	11
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA4_HUMAN
NC score	0.001576 (rank : 87)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	975	Shared Neighborhood Hits	11
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

SUHW4_MOUSE
NC score	0.001329 (rank : 88)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	737	Shared Neighborhood Hits	2
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.