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Network neighborhood for query Sequence : TR10C_HUMAN

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TR10C_HUMAN
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TR10C_HUMAN
θ value	4.05562e-101 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	105
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10D_HUMAN
θ value	7.98882e-65 (rank : 2)	NC score	0.940233 (rank : 2)
Query Neighborhood Hits	105	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10A_HUMAN
θ value	1.73182e-43 (rank : 3)	NC score	0.905580 (rank : 3)
Query Neighborhood Hits	105	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
θ value	1.08726e-37 (rank : 4)	NC score	0.898673 (rank : 4)
Query Neighborhood Hits	105	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
θ value	2.59989e-23 (rank : 5)	NC score	0.834899 (rank : 5)
Query Neighborhood Hits	105	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR26_MOUSE
θ value	8.95645e-16 (rank : 6)	NC score	0.730422 (rank : 6)
Query Neighborhood Hits	105	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR22_MOUSE
θ value	1.33837e-11 (rank : 7)	NC score	0.707214 (rank : 7)
Query Neighborhood Hits	105	Target Neighborhood Hits	97	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR16_MOUSE
θ value	1.9326e-10 (rank : 8)	NC score	0.592400 (rank : 12)
Query Neighborhood Hits	105	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR16_HUMAN
θ value	4.30538e-10 (rank : 9)	NC score	0.592624 (rank : 11)
Query Neighborhood Hits	105	Target Neighborhood Hits	183	Shared Neighborhood Hits	53
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR6_HUMAN
θ value	7.34386e-10 (rank : 10)	NC score	0.649953 (rank : 10)
Query Neighborhood Hits	105	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR23_MOUSE
θ value	9.59137e-10 (rank : 11)	NC score	0.682292 (rank : 8)
Query Neighborhood Hits	105	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR6_MOUSE
θ value	9.59137e-10 (rank : 12)	NC score	0.651574 (rank : 9)
Query Neighborhood Hits	105	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TR11B_HUMAN
θ value	2.36244e-08 (rank : 13)	NC score	0.559650 (rank : 14)
Query Neighborhood Hits	105	Target Neighborhood Hits	92	Shared Neighborhood Hits	40
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR4_MOUSE
θ value	6.87365e-08 (rank : 14)	NC score	0.539191 (rank : 17)
Query Neighborhood Hits	105	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR4_HUMAN
θ value	1.53129e-07 (rank : 15)	NC score	0.534366 (rank : 19)
Query Neighborhood Hits	105	Target Neighborhood Hits	152	Shared Neighborhood Hits	45
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR1A_HUMAN
θ value	3.41135e-07 (rank : 16)	NC score	0.571758 (rank : 13)
Query Neighborhood Hits	105	Target Neighborhood Hits	121	Shared Neighborhood Hits	44
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TR11B_MOUSE
θ value	5.81887e-07 (rank : 17)	NC score	0.543428 (rank : 16)
Query Neighborhood Hits	105	Target Neighborhood Hits	95	Shared Neighborhood Hits	43
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR21_MOUSE
θ value	8.40245e-06 (rank : 18)	NC score	0.456082 (rank : 25)
Query Neighborhood Hits	105	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR1B_HUMAN
θ value	1.87187e-05 (rank : 19)	NC score	0.524541 (rank : 20)
Query Neighborhood Hits	105	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1A_MOUSE
θ value	7.1131e-05 (rank : 20)	NC score	0.536884 (rank : 18)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR21_HUMAN
θ value	7.1131e-05 (rank : 21)	NC score	0.465200 (rank : 24)
Query Neighborhood Hits	105	Target Neighborhood Hits	90	Shared Neighborhood Hits	36
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR8_MOUSE
θ value	9.29e-05 (rank : 22)	NC score	0.445576 (rank : 29)
Query Neighborhood Hits	105	Target Neighborhood Hits	208	Shared Neighborhood Hits	42
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR5_MOUSE
θ value	0.00020696 (rank : 23)	NC score	0.453278 (rank : 26)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

SOX13_MOUSE
θ value	0.00390308 (rank : 24)	NC score	0.040728 (rank : 74)
Query Neighborhood Hits	105	Target Neighborhood Hits	495	Shared Neighborhood Hits	8
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

TNR14_HUMAN
θ value	0.00390308 (rank : 25)	NC score	0.545011 (rank : 15)
Query Neighborhood Hits	105	Target Neighborhood Hits	149	Shared Neighborhood Hits	45
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR7_HUMAN
θ value	0.00665767 (rank : 26)	NC score	0.445645 (rank : 28)
Query Neighborhood Hits	105	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

SCUB3_HUMAN
θ value	0.00869519 (rank : 27)	NC score	0.092988 (rank : 48)
Query Neighborhood Hits	105	Target Neighborhood Hits	428	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TNR1B_MOUSE
θ value	0.00869519 (rank : 28)	NC score	0.495407 (rank : 21)
Query Neighborhood Hits	105	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR8_HUMAN
θ value	0.00869519 (rank : 29)	NC score	0.466282 (rank : 23)
Query Neighborhood Hits	105	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR9_MOUSE
θ value	0.0252991 (rank : 30)	NC score	0.385889 (rank : 35)
Query Neighborhood Hits	105	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR3_HUMAN
θ value	0.0563607 (rank : 31)	NC score	0.482961 (rank : 22)
Query Neighborhood Hits	105	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TRBM_MOUSE
θ value	0.0563607 (rank : 32)	NC score	0.058644 (rank : 60)
Query Neighborhood Hits	105	Target Neighborhood Hits	361	Shared Neighborhood Hits	30
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ZAN_MOUSE
θ value	0.0563607 (rank : 33)	NC score	0.089927 (rank : 50)
Query Neighborhood Hits	105	Target Neighborhood Hits	808	Shared Neighborhood Hits	59
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

PCSK5_MOUSE
θ value	0.0736092 (rank : 34)	NC score	0.128573 (rank : 41)
Query Neighborhood Hits	105	Target Neighborhood Hits	613	Shared Neighborhood Hits	60
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EPHA2_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.029141 (rank : 89)
Query Neighborhood Hits	105	Target Neighborhood Hits	1020	Shared Neighborhood Hits	32
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

TNR9_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.386976 (rank : 34)
Query Neighborhood Hits	105	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

SELPL_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.050369 (rank : 68)
Query Neighborhood Hits	105	Target Neighborhood Hits	588	Shared Neighborhood Hits	19
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

FHL2_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.027964 (rank : 92)
Query Neighborhood Hits	105	Target Neighborhood Hits	539	Shared Neighborhood Hits	18
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

SCUB3_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.092492 (rank : 49)
Query Neighborhood Hits	105	Target Neighborhood Hits	442	Shared Neighborhood Hits	52
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EPHA6_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.032633 (rank : 80)
Query Neighborhood Hits	105	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MLL3_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.043477 (rank : 71)
Query Neighborhood Hits	105	Target Neighborhood Hits	1644	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TNR25_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.424571 (rank : 31)
Query Neighborhood Hits	105	Target Neighborhood Hits	172	Shared Neighborhood Hits	46
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

PCSK5_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.094307 (rank : 47)
Query Neighborhood Hits	105	Target Neighborhood Hits	291	Shared Neighborhood Hits	42
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TNR3_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.436241 (rank : 30)
Query Neighborhood Hits	105	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR7_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.400031 (rank : 33)
Query Neighborhood Hits	105	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

EPHB4_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.029963 (rank : 87)
Query Neighborhood Hits	105	Target Neighborhood Hits	1056	Shared Neighborhood Hits	28
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ADA20_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.014347 (rank : 114)
Query Neighborhood Hits	105	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

EPHB6_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.033229 (rank : 79)
Query Neighborhood Hits	105	Target Neighborhood Hits	912	Shared Neighborhood Hits	24
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

CELR2_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.016707 (rank : 110)
Query Neighborhood Hits	105	Target Neighborhood Hits	657	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

MEGF9_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.074464 (rank : 51)
Query Neighborhood Hits	105	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NFX1_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.054162 (rank : 65)
Query Neighborhood Hits	105	Target Neighborhood Hits	405	Shared Neighborhood Hits	20
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

OGFR_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.023179 (rank : 101)
Query Neighborhood Hits	105	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SREC_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.059166 (rank : 59)
Query Neighborhood Hits	105	Target Neighborhood Hits	645	Shared Neighborhood Hits	48
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

VPS54_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.035744 (rank : 77)
Query Neighborhood Hits	105	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

ATS14_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.013624 (rank : 117)
Query Neighborhood Hits	105	Target Neighborhood Hits	382	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

EP400_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.024023 (rank : 100)
Query Neighborhood Hits	105	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EPHA6_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.033718 (rank : 78)
Query Neighborhood Hits	105	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

FBN3_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.043307 (rank : 72)
Query Neighborhood Hits	105	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ANK2_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.018443 (rank : 108)
Query Neighborhood Hits	105	Target Neighborhood Hits	1615	Shared Neighborhood Hits	29
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

FHL2_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.025777 (rank : 97)
Query Neighborhood Hits	105	Target Neighborhood Hits	533	Shared Neighborhood Hits	15
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

TIE2_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.020261 (rank : 105)
Query Neighborhood Hits	105	Target Neighborhood Hits	1204	Shared Neighborhood Hits	32
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

BSN_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.038773 (rank : 75)
Query Neighborhood Hits	105	Target Neighborhood Hits	1537	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MDC1_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.031464 (rank : 84)
Query Neighborhood Hits	105	Target Neighborhood Hits	1446	Shared Neighborhood Hits	27
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MUCDL_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.032011 (rank : 83)
Query Neighborhood Hits	105	Target Neighborhood Hits	777	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PF21B_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.028877 (rank : 90)
Query Neighborhood Hits	105	Target Neighborhood Hits	278	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

CXXC6_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.030047 (rank : 85)
Query Neighborhood Hits	105	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

E2F4_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.021025 (rank : 104)
Query Neighborhood Hits	105	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

EPHA2_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.024415 (rank : 98)
Query Neighborhood Hits	105	Target Neighborhood Hits	1021	Shared Neighborhood Hits	27
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA5_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.021467 (rank : 103)
Query Neighborhood Hits	105	Target Neighborhood Hits	1009	Shared Neighborhood Hits	17
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPN2_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.028114 (rank : 91)
Query Neighborhood Hits	105	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

EPN2_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.026211 (rank : 96)
Query Neighborhood Hits	105	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

NCTR2_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.030005 (rank : 86)
Query Neighborhood Hits	105	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

TNR5_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.409114 (rank : 32)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

AIM1_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.022718 (rank : 102)
Query Neighborhood Hits	105	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

CASR_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.013701 (rank : 116)
Query Neighborhood Hits	105	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

MAGE1_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.018832 (rank : 107)
Query Neighborhood Hits	105	Target Neighborhood Hits	1389	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MLL3_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.041485 (rank : 73)
Query Neighborhood Hits	105	Target Neighborhood Hits	1399	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

STAB2_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.049135 (rank : 69)
Query Neighborhood Hits	105	Target Neighborhood Hits	528	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CN037_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.027054 (rank : 94)
Query Neighborhood Hits	105	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

FA76B_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.027362 (rank : 93)
Query Neighborhood Hits	105	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FA76B_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.029841 (rank : 88)
Query Neighborhood Hits	105	Target Neighborhood Hits	181	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

KSR2_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.007316 (rank : 124)
Query Neighborhood Hits	105	Target Neighborhood Hits	920	Shared Neighborhood Hits	14
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

NACAM_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.026244 (rank : 95)
Query Neighborhood Hits	105	Target Neighborhood Hits	1866	Shared Neighborhood Hits	31
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NOTC1_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.032190 (rank : 82)
Query Neighborhood Hits	105	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

VTNC_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.012351 (rank : 119)
Query Neighborhood Hits	105	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

FAF1_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.014598 (rank : 113)
Query Neighborhood Hits	105	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

FRAS1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.064517 (rank : 56)
Query Neighborhood Hits	105	Target Neighborhood Hits	747	Shared Neighborhood Hits	53
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF9_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.073410 (rank : 53)
Query Neighborhood Hits	105	Target Neighborhood Hits	557	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SAPS1_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.015837 (rank : 111)
Query Neighborhood Hits	105	Target Neighborhood Hits	704	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEPT9_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.009249 (rank : 122)
Query Neighborhood Hits	105	Target Neighborhood Hits	706	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TBCD4_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.008773 (rank : 123)
Query Neighborhood Hits	105	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

THYG_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.032334 (rank : 81)
Query Neighborhood Hits	105	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

UBR1_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.012218 (rank : 120)
Query Neighborhood Hits	105	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

ZFP38_HUMAN
θ value	5.27518 (rank : 94)	NC score	-0.003110 (rank : 126)
Query Neighborhood Hits	105	Target Neighborhood Hits	766	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

LR37A_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.019157 (rank : 106)
Query Neighborhood Hits	105	Target Neighborhood Hits	720	Shared Neighborhood Hits	19
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MUC1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.017823 (rank : 109)
Query Neighborhood Hits	105	Target Neighborhood Hits	975	Shared Neighborhood Hits	23
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ABL1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.010707 (rank : 121)
Query Neighborhood Hits	105	Target Neighborhood Hits	1220	Shared Neighborhood Hits	22
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABLM1_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.013033 (rank : 118)
Query Neighborhood Hits	105	Target Neighborhood Hits	387	Shared Neighborhood Hits	9
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ABLM1_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.014052 (rank : 115)
Query Neighborhood Hits	105	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

CO8A_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.015097 (rank : 112)
Query Neighborhood Hits	105	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

COMP_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.037198 (rank : 76)
Query Neighborhood Hits	105	Target Neighborhood Hits	290	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

EMR2_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.024261 (rank : 99)
Query Neighborhood Hits	105	Target Neighborhood Hits	345	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

LAMA1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.048431 (rank : 70)
Query Neighborhood Hits	105	Target Neighborhood Hits	804	Shared Neighborhood Hits	51
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TSYL1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.007215 (rank : 125)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

ZN167_HUMAN
θ value	8.99809 (rank : 105)	NC score	-0.003394 (rank : 127)
Query Neighborhood Hits	105	Target Neighborhood Hits	784	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).

EDAR_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.055829 (rank : 62)
Query Neighborhood Hits	105	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.059720 (rank : 58)
Query Neighborhood Hits	105	Target Neighborhood Hits	66	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FRAS1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.066061 (rank : 55)
Query Neighborhood Hits	105	Target Neighborhood Hits	759	Shared Neighborhood Hits	54
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA54_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.052497 (rank : 67)
Query Neighborhood Hits	105	Target Neighborhood Hits	270	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA59_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.052506 (rank : 66)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	24
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA5_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.061178 (rank : 57)
Query Neighborhood Hits	105	Target Neighborhood Hits	976	Shared Neighborhood Hits	53
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.056825 (rank : 61)
Query Neighborhood Hits	105	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.054352 (rank : 64)
Query Neighborhood Hits	105	Target Neighborhood Hits	614	Shared Neighborhood Hits	52
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.055742 (rank : 63)
Query Neighborhood Hits	105	Target Neighborhood Hits	588	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.071152 (rank : 54)
Query Neighborhood Hits	105	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PCSK6_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.073913 (rank : 52)
Query Neighborhood Hits	105	Target Neighborhood Hits	298	Shared Neighborhood Hits	37
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TNR11_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.347310 (rank : 36)
Query Neighborhood Hits	105	Target Neighborhood Hits	135	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.334481 (rank : 37)
Query Neighborhood Hits	105	Target Neighborhood Hits	121	Shared Neighborhood Hits	38
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR18_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.173266 (rank : 38)
Query Neighborhood Hits	105	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR18_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.123617 (rank : 42)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR19_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.096527 (rank : 46)
Query Neighborhood Hits	105	Target Neighborhood Hits	89	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.137607 (rank : 40)
Query Neighborhood Hits	105	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.145950 (rank : 39)
Query Neighborhood Hits	105	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.117144 (rank : 43)
Query Neighborhood Hits	105	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR6B_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.451820 (rank : 27)
Query Neighborhood Hits	105	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR19L_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.099904 (rank : 45)
Query Neighborhood Hits	105	Target Neighborhood Hits	99	Shared Neighborhood Hits	27
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.114928 (rank : 44)
Query Neighborhood Hits	105	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

Hits sorted by NC score

TR10C_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.05562e-101 (rank : 1)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	105
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10D_HUMAN
NC score	0.940233 (rank : 2)	θ value	7.98882e-65 (rank : 2)
Query Neighborhood Hits	105	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10A_HUMAN
NC score	0.905580 (rank : 3)	θ value	1.73182e-43 (rank : 3)
Query Neighborhood Hits	105	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
NC score	0.898673 (rank : 4)	θ value	1.08726e-37 (rank : 4)
Query Neighborhood Hits	105	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
NC score	0.834899 (rank : 5)	θ value	2.59989e-23 (rank : 5)
Query Neighborhood Hits	105	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR26_MOUSE
NC score	0.730422 (rank : 6)	θ value	8.95645e-16 (rank : 6)
Query Neighborhood Hits	105	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR22_MOUSE
NC score	0.707214 (rank : 7)	θ value	1.33837e-11 (rank : 7)
Query Neighborhood Hits	105	Target Neighborhood Hits	97	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
NC score	0.682292 (rank : 8)	θ value	9.59137e-10 (rank : 11)
Query Neighborhood Hits	105	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR6_MOUSE
NC score	0.651574 (rank : 9)	θ value	9.59137e-10 (rank : 12)
Query Neighborhood Hits	105	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_HUMAN
NC score	0.649953 (rank : 10)	θ value	7.34386e-10 (rank : 10)
Query Neighborhood Hits	105	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR16_HUMAN
NC score	0.592624 (rank : 11)	θ value	4.30538e-10 (rank : 9)
Query Neighborhood Hits	105	Target Neighborhood Hits	183	Shared Neighborhood Hits	53
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
NC score	0.592400 (rank : 12)	θ value	1.9326e-10 (rank : 8)
Query Neighborhood Hits	105	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR1A_HUMAN
NC score	0.571758 (rank : 13)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	105	Target Neighborhood Hits	121	Shared Neighborhood Hits	44
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TR11B_HUMAN
NC score	0.559650 (rank : 14)	θ value	2.36244e-08 (rank : 13)
Query Neighborhood Hits	105	Target Neighborhood Hits	92	Shared Neighborhood Hits	40
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR14_HUMAN
NC score	0.545011 (rank : 15)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	105	Target Neighborhood Hits	149	Shared Neighborhood Hits	45
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TR11B_MOUSE
NC score	0.543428 (rank : 16)	θ value	5.81887e-07 (rank : 17)
Query Neighborhood Hits	105	Target Neighborhood Hits	95	Shared Neighborhood Hits	43
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR4_MOUSE
NC score	0.539191 (rank : 17)	θ value	6.87365e-08 (rank : 14)
Query Neighborhood Hits	105	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR1A_MOUSE
NC score	0.536884 (rank : 18)	θ value	7.1131e-05 (rank : 20)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR4_HUMAN
NC score	0.534366 (rank : 19)	θ value	1.53129e-07 (rank : 15)
Query Neighborhood Hits	105	Target Neighborhood Hits	152	Shared Neighborhood Hits	45
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR1B_HUMAN
NC score	0.524541 (rank : 20)	θ value	1.87187e-05 (rank : 19)
Query Neighborhood Hits	105	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
NC score	0.495407 (rank : 21)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	105	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR3_HUMAN
NC score	0.482961 (rank : 22)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	105	Target Neighborhood Hits	145	Shared Neighborhood Hits	46
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR8_HUMAN
NC score	0.466282 (rank : 23)	θ value	0.00869519 (rank : 29)
Query Neighborhood Hits	105	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR21_HUMAN
NC score	0.465200 (rank : 24)	θ value	7.1131e-05 (rank : 21)
Query Neighborhood Hits	105	Target Neighborhood Hits	90	Shared Neighborhood Hits	36
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
NC score	0.456082 (rank : 25)	θ value	8.40245e-06 (rank : 18)
Query Neighborhood Hits	105	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR5_MOUSE
NC score	0.453278 (rank : 26)	θ value	0.00020696 (rank : 23)
Query Neighborhood Hits	105	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR6B_HUMAN
NC score	0.451820 (rank : 27)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	105	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR7_HUMAN
NC score	0.445645 (rank : 28)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	105	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR8_MOUSE
NC score	0.445576 (rank : 29)	θ value	9.29e-05 (rank : 22)
Query Neighborhood Hits	105	Target Neighborhood Hits	208	Shared Neighborhood Hits	42
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR3_MOUSE
NC score	0.436241 (rank : 30)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	105	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR25_HUMAN
NC score	0.424571 (rank : 31)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	105	Target Neighborhood Hits	172	Shared Neighborhood Hits	46
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR5_HUMAN
NC score	0.409114 (rank : 32)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	105	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR7_MOUSE
NC score	0.400031 (rank : 33)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	105	Target Neighborhood Hits	112	Shared Neighborhood Hits	40
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR9_HUMAN
NC score	0.386976 (rank : 34)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	105	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
NC score	0.385889 (rank : 35)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	105	Target Neighborhood Hits	137	Shared Neighborhood Hits	48
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR11_HUMAN
NC score	0.347310 (rank : 36)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	105	Target Neighborhood Hits	135	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
NC score	0.334481 (rank : 37)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	105	Target Neighborhood Hits	121	Shared Neighborhood Hits	38
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR18_HUMAN
NC score	0.173266 (rank : 38)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	105	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR27_HUMAN
NC score	0.145950 (rank : 39)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	105	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_MOUSE
NC score	0.137607 (rank : 40)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	105	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCSK5_MOUSE
NC score	0.128573 (rank : 41)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	105	Target Neighborhood Hits	613	Shared Neighborhood Hits	60
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TNR18_MOUSE
NC score	0.123617 (rank : 42)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	105	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR27_MOUSE
NC score	0.117144 (rank : 43)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	105	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_MOUSE
NC score	0.114928 (rank : 44)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	105	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TR19L_HUMAN
NC score	0.099904 (rank : 45)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	105	Target Neighborhood Hits	99	Shared Neighborhood Hits	27
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR19_HUMAN
NC score	0.096527 (rank : 46)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	105	Target Neighborhood Hits	89	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCSK5_HUMAN
NC score	0.094307 (rank : 47)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	105	Target Neighborhood Hits	291	Shared Neighborhood Hits	42
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SCUB3_HUMAN
NC score	0.092988 (rank : 48)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	105	Target Neighborhood Hits	428	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
NC score	0.092492 (rank : 49)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	105	Target Neighborhood Hits	442	Shared Neighborhood Hits	52
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ZAN_MOUSE
NC score	0.089927 (rank : 50)	θ value	0.0563607 (rank : 33)
Query Neighborhood Hits	105	Target Neighborhood Hits	808	Shared Neighborhood Hits	59
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MEGF9_MOUSE
NC score	0.074464 (rank : 51)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	105	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PCSK6_HUMAN
NC score	0.073913 (rank : 52)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	105	Target Neighborhood Hits	298	Shared Neighborhood Hits	37
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

MEGF9_HUMAN
NC score	0.073410 (rank : 53)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	105	Target Neighborhood Hits	557	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMC3_MOUSE
NC score	0.071152 (rank : 54)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	105	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

FRAS1_HUMAN
NC score	0.066061 (rank : 55)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	105	Target Neighborhood Hits	759	Shared Neighborhood Hits	54
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
NC score	0.064517 (rank : 56)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	105	Target Neighborhood Hits	747	Shared Neighborhood Hits	53
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA5_HUMAN
NC score	0.061178 (rank : 57)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	105	Target Neighborhood Hits	976	Shared Neighborhood Hits	53
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EDAR_MOUSE
NC score	0.059720 (rank : 58)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	105	Target Neighborhood Hits	66	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

SREC_HUMAN
NC score	0.059166 (rank : 59)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	105	Target Neighborhood Hits	645	Shared Neighborhood Hits	48
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TRBM_MOUSE
NC score	0.058644 (rank : 60)	θ value	0.0563607 (rank : 32)
Query Neighborhood Hits	105	Target Neighborhood Hits	361	Shared Neighborhood Hits	30
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMA5_MOUSE
NC score	0.056825 (rank : 61)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	105	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EDAR_HUMAN
NC score	0.055829 (rank : 62)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	105	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

LAMC3_HUMAN
NC score	0.055742 (rank : 63)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	105	Target Neighborhood Hits	588	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC2_MOUSE
NC score	0.054352 (rank : 64)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	105	Target Neighborhood Hits	614	Shared Neighborhood Hits	52
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NFX1_HUMAN
NC score	0.054162 (rank : 65)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	105	Target Neighborhood Hits	405	Shared Neighborhood Hits	20
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

KRA59_HUMAN
NC score	0.052506 (rank : 66)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	105	Target Neighborhood Hits	310	Shared Neighborhood Hits	24
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA54_HUMAN
NC score	0.052497 (rank : 67)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	105	Target Neighborhood Hits	270	Shared Neighborhood Hits	19
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

SELPL_MOUSE
NC score	0.050369 (rank : 68)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	105	Target Neighborhood Hits	588	Shared Neighborhood Hits	19
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

STAB2_MOUSE
NC score	0.049135 (rank : 69)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	105	Target Neighborhood Hits	528	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LAMA1_HUMAN
NC score	0.048431 (rank : 70)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	105	Target Neighborhood Hits	804	Shared Neighborhood Hits	51
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MLL3_HUMAN
NC score	0.043477 (rank : 71)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	105	Target Neighborhood Hits	1644	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

FBN3_HUMAN
NC score	0.043307 (rank : 72)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	105	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MLL3_MOUSE
NC score	0.041485 (rank : 73)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	105	Target Neighborhood Hits	1399	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SOX13_MOUSE
NC score	0.040728 (rank : 74)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	105	Target Neighborhood Hits	495	Shared Neighborhood Hits	8
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

BSN_HUMAN
NC score	0.038773 (rank : 75)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	105	Target Neighborhood Hits	1537	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

COMP_MOUSE
NC score	0.037198 (rank : 76)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	105	Target Neighborhood Hits	290	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

VPS54_MOUSE
NC score	0.035744 (rank : 77)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	105	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SPW0, Q8BPB3, Q8CFZ7, Q8CHL5, Q8R3R4, Q8R3X1	Gene names	Vps54
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p homolog).

EPHA6_HUMAN
NC score	0.033718 (rank : 78)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	105	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB6_HUMAN
NC score	0.033229 (rank : 79)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	105	Target Neighborhood Hits	912	Shared Neighborhood Hits	24
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHA6_MOUSE
NC score	0.032633 (rank : 80)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	105	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

THYG_MOUSE
NC score	0.032334 (rank : 81)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	105	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

NOTC1_HUMAN
NC score	0.032190 (rank : 82)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	105	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MUCDL_HUMAN
NC score	0.032011 (rank : 83)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	105	Target Neighborhood Hits	777	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MDC1_HUMAN
NC score	0.031464 (rank : 84)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	105	Target Neighborhood Hits	1446	Shared Neighborhood Hits	27
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CXXC6_HUMAN
NC score	0.030047 (rank : 85)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	105	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

NCTR2_HUMAN
NC score	0.030005 (rank : 86)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	105	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	O95944, Q9H562, Q9H563, Q9H564, Q9UMT1, Q9UMT2	Gene names	NCR2, LY95
Domain Architecture
Description	Natural cytotoxicity triggering receptor 2 precursor (Natural killer cell p44-related protein) (NKp44) (NK-p44) (NK cell-activating receptor) (Lymphocyte antigen 95 homolog) (CD336 antigen).

EPHB4_HUMAN
NC score	0.029963 (rank : 87)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	105	Target Neighborhood Hits	1056	Shared Neighborhood Hits	28
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FA76B_MOUSE
NC score	0.029841 (rank : 88)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	105	Target Neighborhood Hits	181	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

EPHA2_MOUSE
NC score	0.029141 (rank : 89)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	105	Target Neighborhood Hits	1020	Shared Neighborhood Hits	32
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

PF21B_MOUSE
NC score	0.028877 (rank : 90)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	105	Target Neighborhood Hits	278	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

EPN2_HUMAN
NC score	0.028114 (rank : 91)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	105	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

FHL2_MOUSE
NC score	0.027964 (rank : 92)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	105	Target Neighborhood Hits	539	Shared Neighborhood Hits	18
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

FA76B_HUMAN
NC score	0.027362 (rank : 93)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	105	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

CN037_HUMAN
NC score	0.027054 (rank : 94)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	105	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

NACAM_MOUSE
NC score	0.026244 (rank : 95)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	105	Target Neighborhood Hits	1866	Shared Neighborhood Hits	31
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

EPN2_MOUSE
NC score	0.026211 (rank : 96)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	105	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

FHL2_HUMAN
NC score	0.025777 (rank : 97)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	105	Target Neighborhood Hits	533	Shared Neighborhood Hits	15
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

EPHA2_HUMAN
NC score	0.024415 (rank : 98)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	105	Target Neighborhood Hits	1021	Shared Neighborhood Hits	27
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EMR2_HUMAN
NC score	0.024261 (rank : 99)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	105	Target Neighborhood Hits	345	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EP400_MOUSE
NC score	0.024023 (rank : 100)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	105	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

OGFR_HUMAN
NC score	0.023179 (rank : 101)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	105	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

AIM1_HUMAN
NC score	0.022718 (rank : 102)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	105	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

EPHA5_HUMAN
NC score	0.021467 (rank : 103)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	105	Target Neighborhood Hits	1009	Shared Neighborhood Hits	17
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

E2F4_HUMAN
NC score	0.021025 (rank : 104)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	105	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

TIE2_MOUSE
NC score	0.020261 (rank : 105)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	105	Target Neighborhood Hits	1204	Shared Neighborhood Hits	32
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

LR37A_HUMAN
NC score	0.019157 (rank : 106)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	105	Target Neighborhood Hits	720	Shared Neighborhood Hits	19
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MAGE1_HUMAN
NC score	0.018832 (rank : 107)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	105	Target Neighborhood Hits	1389	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ANK2_HUMAN
NC score	0.018443 (rank : 108)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	105	Target Neighborhood Hits	1615	Shared Neighborhood Hits	29
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MUC1_HUMAN
NC score	0.017823 (rank : 109)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	105	Target Neighborhood Hits	975	Shared Neighborhood Hits	23
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CELR2_HUMAN
NC score	0.016707 (rank : 110)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	105	Target Neighborhood Hits	657	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

SAPS1_HUMAN
NC score	0.015837 (rank : 111)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	105	Target Neighborhood Hits	704	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CO8A_HUMAN
NC score	0.015097 (rank : 112)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	105	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

FAF1_MOUSE
NC score	0.014598 (rank : 113)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	105	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

ADA20_HUMAN
NC score	0.014347 (rank : 114)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	105	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ABLM1_MOUSE
NC score	0.014052 (rank : 115)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	105	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

CASR_MOUSE
NC score	0.013701 (rank : 116)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	105	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

ATS14_HUMAN
NC score	0.013624 (rank : 117)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	105	Target Neighborhood Hits	382	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ABLM1_HUMAN
NC score	0.013033 (rank : 118)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	105	Target Neighborhood Hits	387	Shared Neighborhood Hits	9
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

VTNC_MOUSE
NC score	0.012351 (rank : 119)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	105	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

UBR1_HUMAN
NC score	0.012218 (rank : 120)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	105	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

ABL1_HUMAN
NC score	0.010707 (rank : 121)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	105	Target Neighborhood Hits	1220	Shared Neighborhood Hits	22
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SEPT9_HUMAN
NC score	0.009249 (rank : 122)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	105	Target Neighborhood Hits	706	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TBCD4_HUMAN
NC score	0.008773 (rank : 123)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	105	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

KSR2_HUMAN
NC score	0.007316 (rank : 124)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	105	Target Neighborhood Hits	920	Shared Neighborhood Hits	14
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

TSYL1_MOUSE
NC score	0.007215 (rank : 125)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	105	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

ZFP38_HUMAN
NC score	-0.003110 (rank : 126)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	105	Target Neighborhood Hits	766	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

ZN167_HUMAN
NC score	-0.003394 (rank : 127)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	105	Target Neighborhood Hits	784	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P0L1, Q6WL09, Q96FQ2	Gene names	ZNF167, ZNF448, ZNF64
Domain Architecture	No domain graphic available
Description	Zinc finger protein 167 (Zinc finger protein 64) (Zinc finger protein 448) (ZFP).