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Network neighborhood for query Sequence : TR10B_HUMAN

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TR10B_HUMAN
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TR10B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10A_HUMAN
θ value	4.96919e-91 (rank : 2)	NC score	0.943151 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10D_HUMAN
θ value	7.19216e-82 (rank : 3)	NC score	0.947615 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10C_HUMAN
θ value	1.08726e-37 (rank : 4)	NC score	0.898673 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10B_MOUSE
θ value	1.33217e-27 (rank : 5)	NC score	0.840359 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR6_HUMAN
θ value	1.74796e-11 (rank : 6)	NC score	0.633588 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR3_HUMAN
θ value	1.63604e-09 (rank : 7)	NC score	0.521036 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	145	Shared Neighborhood Hits	44
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR1B_HUMAN
θ value	4.45536e-07 (rank : 8)	NC score	0.530298 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	127	Shared Neighborhood Hits	42
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR26_MOUSE
θ value	5.81887e-07 (rank : 9)	NC score	0.646571 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR6_MOUSE
θ value	5.81887e-07 (rank : 10)	NC score	0.605717 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR16_MOUSE
θ value	2.88788e-06 (rank : 11)	NC score	0.518350 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	178	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR22_MOUSE
θ value	2.88788e-06 (rank : 12)	NC score	0.632622 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR3_MOUSE
θ value	3.77169e-06 (rank : 13)	NC score	0.467796 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	113	Shared Neighborhood Hits	42
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR1B_MOUSE
θ value	4.92598e-06 (rank : 14)	NC score	0.502761 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	123	Shared Neighborhood Hits	44
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR14_HUMAN
θ value	6.43352e-06 (rank : 15)	NC score	0.538066 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_HUMAN
θ value	6.43352e-06 (rank : 16)	NC score	0.516810 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1A_HUMAN
θ value	6.43352e-06 (rank : 17)	NC score	0.529521 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	121	Shared Neighborhood Hits	47
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR8_MOUSE
θ value	8.40245e-06 (rank : 18)	NC score	0.444192 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	208	Shared Neighborhood Hits	39
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

LAMC3_MOUSE
θ value	1.87187e-05 (rank : 19)	NC score	0.085444 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	624	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TNR23_MOUSE
θ value	1.87187e-05 (rank : 20)	NC score	0.606974 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	114	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR4_MOUSE
θ value	1.87187e-05 (rank : 21)	NC score	0.505559 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TR11B_HUMAN
θ value	3.19293e-05 (rank : 22)	NC score	0.523202 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR21_HUMAN
θ value	9.29e-05 (rank : 23)	NC score	0.441706 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR11B_MOUSE
θ value	9.29e-05 (rank : 24)	NC score	0.503870 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1A_MOUSE
θ value	0.000121331 (rank : 25)	NC score	0.500812 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR21_MOUSE
θ value	0.00020696 (rank : 26)	NC score	0.427244 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR8_HUMAN
θ value	0.00020696 (rank : 27)	NC score	0.471316 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR4_HUMAN
θ value	0.000602161 (rank : 28)	NC score	0.490159 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	152	Shared Neighborhood Hits	46
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR25_HUMAN
θ value	0.00102713 (rank : 29)	NC score	0.420789 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	172	Shared Neighborhood Hits	49
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

PCSK5_MOUSE
θ value	0.0252991 (rank : 30)	NC score	0.116054 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	613	Shared Neighborhood Hits	60
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EPHA1_HUMAN
θ value	0.0330416 (rank : 31)	NC score	0.021282 (rank : 84)
Query Neighborhood Hits	71	Target Neighborhood Hits	997	Shared Neighborhood Hits	21
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

TNR6B_HUMAN
θ value	0.0563607 (rank : 32)	NC score	0.449046 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR7_MOUSE
θ value	0.0961366 (rank : 33)	NC score	0.349685 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR5_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.390022 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

EPHA6_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.025851 (rank : 79)
Query Neighborhood Hits	71	Target Neighborhood Hits	959	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

TNR5_MOUSE
θ value	0.163984 (rank : 36)	NC score	0.410684 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR7_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.388278 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

SCUB3_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.088067 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	442	Shared Neighborhood Hits	54
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TNR11_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.351822 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

EPHA1_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.020475 (rank : 85)
Query Neighborhood Hits	71	Target Neighborhood Hits	958	Shared Neighborhood Hits	25
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

UPAR_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.040758 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q03405, Q12876, Q15845, Q16887, Q9NYC8, Q9UD69, Q9UEA6, Q9UM92, Q9UMV0	Gene names	PLAUR, MO3, UPAR
Domain Architecture
Description	Urokinase plasminogen activator surface receptor precursor (uPAR) (U- PAR) (Monocyte activation antigen Mo3) (CD87 antigen).

PCSK5_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.089743 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	291	Shared Neighborhood Hits	45
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

FBN2_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.044307 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	560	Shared Neighborhood Hits	38
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.045506 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	549	Shared Neighborhood Hits	38
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP1B_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.027622 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	606	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MATN2_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.046038 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	356	Shared Neighborhood Hits	31
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

SYNG_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.026917 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TNR9_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.338831 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

EPHA2_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.022323 (rank : 82)
Query Neighborhood Hits	71	Target Neighborhood Hits	1020	Shared Neighborhood Hits	31
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

SCUB3_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.088034 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	428	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TNR11_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.336634 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

HMCN1_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.018685 (rank : 86)
Query Neighborhood Hits	71	Target Neighborhood Hits	983	Shared Neighborhood Hits	23
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

K0562_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.035242 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

MATN2_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.044518 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	365	Shared Neighborhood Hits	31
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

EPHA6_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.023552 (rank : 81)
Query Neighborhood Hits	71	Target Neighborhood Hits	946	Shared Neighborhood Hits	18
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

K0562_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.035216 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

THYG_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.025891 (rank : 78)
Query Neighborhood Hits	71	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

EPHB4_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.022102 (rank : 83)
Query Neighborhood Hits	71	Target Neighborhood Hits	1056	Shared Neighborhood Hits	31
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FATH_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.011406 (rank : 88)
Query Neighborhood Hits	71	Target Neighborhood Hits	570	Shared Neighborhood Hits	24
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN5_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.042188 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	317	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN3_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.046471 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	543	Shared Neighborhood Hits	40
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTB1L_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.038228 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.038004 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	479	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PCSK6_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.068865 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	298	Shared Neighborhood Hits	39
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SREC_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.052521 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MUC2_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.013969 (rank : 87)
Query Neighborhood Hits	71	Target Neighborhood Hits	906	Shared Neighborhood Hits	23
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RIPK1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.011103 (rank : 89)
Query Neighborhood Hits	71	Target Neighborhood Hits	891	Shared Neighborhood Hits	16
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

VLDLR_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.023958 (rank : 80)
Query Neighborhood Hits	71	Target Neighborhood Hits	383	Shared Neighborhood Hits	20
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

FBLN5_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.043229 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

MEGF9_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.053014 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	896	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

RIPK1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.010160 (rank : 90)
Query Neighborhood Hits	71	Target Neighborhood Hits	874	Shared Neighborhood Hits	14
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

EDAR_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.052774 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	84	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.052785 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FRAS1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.053957 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	759	Shared Neighborhood Hits	54
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.050085 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	747	Shared Neighborhood Hits	52
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.054571 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	976	Shared Neighborhood Hits	55
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.052331 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.052584 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	614	Shared Neighborhood Hits	53
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.060486 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	588	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF9_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.052814 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	557	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TNR18_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.161100 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR18_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.108244 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR19_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.089133 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.120721 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.147022 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.121798 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR9_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.328427 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TR19L_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.097919 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.109256 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.066207 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	808	Shared Neighborhood Hits	46
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

TR10B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10D_HUMAN
NC score	0.947615 (rank : 2)	θ value	7.19216e-82 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10A_HUMAN
NC score	0.943151 (rank : 3)	θ value	4.96919e-91 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10C_HUMAN
NC score	0.898673 (rank : 4)	θ value	1.08726e-37 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10B_MOUSE
NC score	0.840359 (rank : 5)	θ value	1.33217e-27 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR26_MOUSE
NC score	0.646571 (rank : 6)	θ value	5.81887e-07 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR6_HUMAN
NC score	0.633588 (rank : 7)	θ value	1.74796e-11 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR22_MOUSE
NC score	0.632622 (rank : 8)	θ value	2.88788e-06 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
NC score	0.606974 (rank : 9)	θ value	1.87187e-05 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	114	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR6_MOUSE
NC score	0.605717 (rank : 10)	θ value	5.81887e-07 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR14_HUMAN
NC score	0.538066 (rank : 11)	θ value	6.43352e-06 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	149	Shared Neighborhood Hits	47
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR1B_HUMAN
NC score	0.530298 (rank : 12)	θ value	4.45536e-07 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	127	Shared Neighborhood Hits	42
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1A_HUMAN
NC score	0.529521 (rank : 13)	θ value	6.43352e-06 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	121	Shared Neighborhood Hits	47
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TR11B_HUMAN
NC score	0.523202 (rank : 14)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
NC score	0.521036 (rank : 15)	θ value	1.63604e-09 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	145	Shared Neighborhood Hits	44
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR16_MOUSE
NC score	0.518350 (rank : 16)	θ value	2.88788e-06 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	178	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR16_HUMAN
NC score	0.516810 (rank : 17)	θ value	6.43352e-06 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR4_MOUSE
NC score	0.505559 (rank : 18)	θ value	1.87187e-05 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TR11B_MOUSE
NC score	0.503870 (rank : 19)	θ value	9.29e-05 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_MOUSE
NC score	0.502761 (rank : 20)	θ value	4.92598e-06 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	123	Shared Neighborhood Hits	44
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR1A_MOUSE
NC score	0.500812 (rank : 21)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	131	Shared Neighborhood Hits	44
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR4_HUMAN
NC score	0.490159 (rank : 22)	θ value	0.000602161 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	152	Shared Neighborhood Hits	46
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR8_HUMAN
NC score	0.471316 (rank : 23)	θ value	0.00020696 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR3_MOUSE
NC score	0.467796 (rank : 24)	θ value	3.77169e-06 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	113	Shared Neighborhood Hits	42
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR6B_HUMAN
NC score	0.449046 (rank : 25)	θ value	0.0563607 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR8_MOUSE
NC score	0.444192 (rank : 26)	θ value	8.40245e-06 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	208	Shared Neighborhood Hits	39
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR21_HUMAN
NC score	0.441706 (rank : 27)	θ value	9.29e-05 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
NC score	0.427244 (rank : 28)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR25_HUMAN
NC score	0.420789 (rank : 29)	θ value	0.00102713 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	172	Shared Neighborhood Hits	49
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR5_MOUSE
NC score	0.410684 (rank : 30)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR5_HUMAN
NC score	0.390022 (rank : 31)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR7_HUMAN
NC score	0.388278 (rank : 32)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR11_HUMAN
NC score	0.351822 (rank : 33)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR7_MOUSE
NC score	0.349685 (rank : 34)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR9_MOUSE
NC score	0.338831 (rank : 35)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	137	Shared Neighborhood Hits	46
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR11_MOUSE
NC score	0.336634 (rank : 36)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR9_HUMAN
NC score	0.328427 (rank : 37)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	71	Target Neighborhood Hits	166	Shared Neighborhood Hits	48
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR18_HUMAN
NC score	0.161100 (rank : 38)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	71	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR27_HUMAN
NC score	0.147022 (rank : 39)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	71	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
NC score	0.121798 (rank : 40)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_MOUSE
NC score	0.120721 (rank : 41)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	71	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCSK5_MOUSE
NC score	0.116054 (rank : 42)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	613	Shared Neighborhood Hits	60
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TR19L_MOUSE
NC score	0.109256 (rank : 43)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TNR18_MOUSE
NC score	0.108244 (rank : 44)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	71	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TR19L_HUMAN
NC score	0.097919 (rank : 45)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	71	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

PCSK5_HUMAN
NC score	0.089743 (rank : 46)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	291	Shared Neighborhood Hits	45
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TNR19_HUMAN
NC score	0.089133 (rank : 47)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

SCUB3_MOUSE
NC score	0.088067 (rank : 48)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	442	Shared Neighborhood Hits	54
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.088034 (rank : 49)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	428	Shared Neighborhood Hits	51
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMC3_MOUSE
NC score	0.085444 (rank : 50)	θ value	1.87187e-05 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	624	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PCSK6_HUMAN
NC score	0.068865 (rank : 51)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	298	Shared Neighborhood Hits	39
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

ZAN_MOUSE
NC score	0.066207 (rank : 52)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	71	Target Neighborhood Hits	808	Shared Neighborhood Hits	46
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LAMC3_HUMAN
NC score	0.060486 (rank : 53)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	71	Target Neighborhood Hits	588	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_HUMAN
NC score	0.054571 (rank : 54)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	976	Shared Neighborhood Hits	55
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FRAS1_HUMAN
NC score	0.053957 (rank : 55)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	759	Shared Neighborhood Hits	54
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF9_MOUSE
NC score	0.053014 (rank : 56)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	896	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_HUMAN
NC score	0.052814 (rank : 57)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	71	Target Neighborhood Hits	557	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EDAR_MOUSE
NC score	0.052785 (rank : 58)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

EDAR_HUMAN
NC score	0.052774 (rank : 59)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	84	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

LAMC2_MOUSE
NC score	0.052584 (rank : 60)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	71	Target Neighborhood Hits	614	Shared Neighborhood Hits	53
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

SREC_HUMAN
NC score	0.052521 (rank : 61)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMA5_MOUSE
NC score	0.052331 (rank : 62)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FRAS1_MOUSE
NC score	0.050085 (rank : 63)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	747	Shared Neighborhood Hits	52
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FBN3_HUMAN
NC score	0.046471 (rank : 64)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	543	Shared Neighborhood Hits	40
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MATN2_MOUSE
NC score	0.046038 (rank : 65)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	356	Shared Neighborhood Hits	31
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

FBN2_MOUSE
NC score	0.045506 (rank : 66)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	549	Shared Neighborhood Hits	38
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

MATN2_HUMAN
NC score	0.044518 (rank : 67)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	365	Shared Neighborhood Hits	31
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FBN2_HUMAN
NC score	0.044307 (rank : 68)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	560	Shared Neighborhood Hits	38
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN5_HUMAN
NC score	0.043229 (rank : 69)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
NC score	0.042188 (rank : 70)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	317	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

UPAR_HUMAN
NC score	0.040758 (rank : 71)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q03405, Q12876, Q15845, Q16887, Q9NYC8, Q9UD69, Q9UEA6, Q9UM92, Q9UMV0	Gene names	PLAUR, MO3, UPAR
Domain Architecture
Description	Urokinase plasminogen activator surface receptor precursor (uPAR) (U- PAR) (Monocyte activation antigen Mo3) (CD87 antigen).

LTB1L_MOUSE
NC score	0.038228 (rank : 72)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.038004 (rank : 73)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	479	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

K0562_HUMAN
NC score	0.035242 (rank : 74)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	O60308, Q5JSQ3, Q5SR24, Q5SR25, Q6PKF5, Q86W32, Q86X14	Gene names	KIAA0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

K0562_MOUSE
NC score	0.035216 (rank : 75)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

LRP1B_MOUSE
NC score	0.027622 (rank : 76)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	606	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SYNG_HUMAN
NC score	0.026917 (rank : 77)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

THYG_MOUSE
NC score	0.025891 (rank : 78)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

EPHA6_HUMAN
NC score	0.025851 (rank : 79)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	959	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

VLDLR_HUMAN
NC score	0.023958 (rank : 80)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	383	Shared Neighborhood Hits	20
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

EPHA6_MOUSE
NC score	0.023552 (rank : 81)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	946	Shared Neighborhood Hits	18
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA2_MOUSE
NC score	0.022323 (rank : 82)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	1020	Shared Neighborhood Hits	31
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHB4_HUMAN
NC score	0.022102 (rank : 83)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	1056	Shared Neighborhood Hits	31
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHA1_HUMAN
NC score	0.021282 (rank : 84)	θ value	0.0330416 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	997	Shared Neighborhood Hits	21
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
NC score	0.020475 (rank : 85)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	958	Shared Neighborhood Hits	25
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

HMCN1_HUMAN
NC score	0.018685 (rank : 86)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	983	Shared Neighborhood Hits	23
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

MUC2_HUMAN
NC score	0.013969 (rank : 87)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	906	Shared Neighborhood Hits	23
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

FATH_HUMAN
NC score	0.011406 (rank : 88)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	570	Shared Neighborhood Hits	24
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

RIPK1_HUMAN
NC score	0.011103 (rank : 89)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	891	Shared Neighborhood Hits	16
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
NC score	0.010160 (rank : 90)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	874	Shared Neighborhood Hits	14
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).