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Network neighborhood for query Sequence : POL2_MOUSE

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POL2_MOUSE
SwissProt Accessions	P11369, Q60713, Q61787	Gene names	Pol
Domain Architecture
Description	Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element- 1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LIN1_HUMAN
θ value	0 (rank : 1)	NC score	0.913898 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

POL2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	P11369, Q60713, Q61787	Gene names	Pol
Domain Architecture
Description	Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element- 1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease].

POF1B_MOUSE
θ value	0.00102713 (rank : 3)	NC score	0.084846 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	530	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

APEX1_MOUSE
θ value	0.00390308 (rank : 4)	NC score	0.237481 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P28352	Gene names	Apex1, Ape, Apex
Domain Architecture
Description	DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP endonuclease 1) (APEX nuclease) (APEN).

APEX1_HUMAN
θ value	0.0330416 (rank : 5)	NC score	0.210660 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P27695, Q969L5, Q99775	Gene names	APEX1, APE, APEX, APX, HAP1, REF1
Domain Architecture
Description	DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP endonuclease 1) (APEX nuclease) (APEN) (REF-1 protein).

APEX2_MOUSE
θ value	0.125558 (rank : 6)	NC score	0.150866 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

CK5P2_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.031536 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	1433	Shared Neighborhood Hits	21
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MACF1_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.028416 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	1341	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

ATAD2_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.028862 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

GOGA3_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.032838 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	1437	Shared Neighborhood Hits	21
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

KNTC2_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.038986 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	673	Shared Neighborhood Hits	15
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

CN045_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.052544 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

GLCE_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.045428 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPS3, Q99MM0	Gene names	Glce
Domain Architecture
Description	D-glucuronyl C5-epimerase (EC 5.1.3.-) (Heparin/heparan sulfate:glucuronic acid C5 epimerase).

GOGA5_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.037636 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	1168	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

INVS_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.010560 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	455	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

KNTC2_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.035044 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	692	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

MPP5_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.021948 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.021989 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

CTGE5_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.024606 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	928	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

MACF1_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.025691 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	1313	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

CA065_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.029350 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	469	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

BICD1_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.021666 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	844	Shared Neighborhood Hits	16
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CTRO_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.010676 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	2344	Shared Neighborhood Hits	19
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MLF1_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.024209 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWV4, O70217	Gene names	Mlf1, Hls7
Domain Architecture	No domain graphic available
Description	Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) (Hematopoietic lineage switch 7).

CENPE_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.024452 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	2060	Shared Neighborhood Hits	22
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CTRO_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.010217 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	2092	Shared Neighborhood Hits	19
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DHB3_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.014202 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	P70385	Gene names	Hsd17b3, Edh17b3
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 3 (EC 1.1.1.62) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase).

TBCD3_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.015325 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

CASC5_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.020161 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	376	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

COA1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.011766 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

CTND1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.009268 (rank : 41)
Query Neighborhood Hits	39	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

LA_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.018726 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P32067	Gene names	Ssb, Ss-b
Domain Architecture
Description	Lupus La protein homolog (La ribonucleoprotein) (La autoantigen homolog).

RTP2_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.013907 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q80ZI2	Gene names	Rtp2, Gm605
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 2.

AKAP9_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.025906 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	1710	Shared Neighborhood Hits	21
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ATAD2_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.018622 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	322	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

GLCE_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.031769 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O94923, Q6GUQ2	Gene names	GLCE, KIAA0836
Domain Architecture	No domain graphic available
Description	D-glucuronyl C5-epimerase (EC 5.1.3.-) (Heparin/heparan sulfate:glucuronic acid C5 epimerase).

RINT1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.015127 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NUQ1, Q75MG9, Q75MH0, Q96IW8, Q9H229, Q9HAD9	Gene names	RINT1
Domain Architecture	No domain graphic available
Description	RAD50-interacting protein 1 (RAD50 interactor 1) (Protein RINT-1) (HsRINT-1).

SYNE1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.019577 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	1484	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TAB2_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.010690 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

APEX2_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.116962 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

LRC42_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.053264 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	25	Shared Neighborhood Hits	1
SwissProt Accessions	Q8R2U7, Q3TE62, Q9CTP9	Gene names	Lrrc42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

Hits sorted by NC score

POL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	P11369, Q60713, Q61787	Gene names	Pol
Domain Architecture
Description	Retrovirus-related Pol polyprotein LINE-1 (Long interspersed element- 1) (L1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease].

LIN1_HUMAN
NC score	0.913898 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	187	Shared Neighborhood Hits	12
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

APEX1_MOUSE
NC score	0.237481 (rank : 3)	θ value	0.00390308 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P28352	Gene names	Apex1, Ape, Apex
Domain Architecture
Description	DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP endonuclease 1) (APEX nuclease) (APEN).

APEX1_HUMAN
NC score	0.210660 (rank : 4)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P27695, Q969L5, Q99775	Gene names	APEX1, APE, APEX, APX, HAP1, REF1
Domain Architecture
Description	DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP endonuclease 1) (APEX nuclease) (APEN) (REF-1 protein).

APEX2_MOUSE
NC score	0.150866 (rank : 5)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

APEX2_HUMAN
NC score	0.116962 (rank : 6)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	39	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

POF1B_MOUSE
NC score	0.084846 (rank : 7)	θ value	0.00102713 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	530	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

LRC42_MOUSE
NC score	0.053264 (rank : 8)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	39	Target Neighborhood Hits	25	Shared Neighborhood Hits	1
SwissProt Accessions	Q8R2U7, Q3TE62, Q9CTP9	Gene names	Lrrc42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

CN045_HUMAN
NC score	0.052544 (rank : 9)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

GLCE_MOUSE
NC score	0.045428 (rank : 10)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPS3, Q99MM0	Gene names	Glce
Domain Architecture
Description	D-glucuronyl C5-epimerase (EC 5.1.3.-) (Heparin/heparan sulfate:glucuronic acid C5 epimerase).

KNTC2_HUMAN
NC score	0.038986 (rank : 11)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	673	Shared Neighborhood Hits	15
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

GOGA5_HUMAN
NC score	0.037636 (rank : 12)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	1168	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

KNTC2_MOUSE
NC score	0.035044 (rank : 13)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	692	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

GOGA3_MOUSE
NC score	0.032838 (rank : 14)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	1437	Shared Neighborhood Hits	21
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GLCE_HUMAN
NC score	0.031769 (rank : 15)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O94923, Q6GUQ2	Gene names	GLCE, KIAA0836
Domain Architecture	No domain graphic available
Description	D-glucuronyl C5-epimerase (EC 5.1.3.-) (Heparin/heparan sulfate:glucuronic acid C5 epimerase).

CK5P2_HUMAN
NC score	0.031536 (rank : 16)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	1433	Shared Neighborhood Hits	21
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CA065_HUMAN
NC score	0.029350 (rank : 17)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	469	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

ATAD2_MOUSE
NC score	0.028862 (rank : 18)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

MACF1_HUMAN
NC score	0.028416 (rank : 19)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	1341	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

AKAP9_HUMAN
NC score	0.025906 (rank : 20)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	1710	Shared Neighborhood Hits	21
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

MACF1_MOUSE
NC score	0.025691 (rank : 21)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	1313	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

CTGE5_MOUSE
NC score	0.024606 (rank : 22)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	928	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CENPE_HUMAN
NC score	0.024452 (rank : 23)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	2060	Shared Neighborhood Hits	22
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MLF1_MOUSE
NC score	0.024209 (rank : 24)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWV4, O70217	Gene names	Mlf1, Hls7
Domain Architecture	No domain graphic available
Description	Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) (Hematopoietic lineage switch 7).

MPP5_MOUSE
NC score	0.021989 (rank : 25)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

MPP5_HUMAN
NC score	0.021948 (rank : 26)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

BICD1_HUMAN
NC score	0.021666 (rank : 27)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	844	Shared Neighborhood Hits	16
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CASC5_HUMAN
NC score	0.020161 (rank : 28)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	376	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

SYNE1_HUMAN
NC score	0.019577 (rank : 29)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	1484	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

LA_MOUSE
NC score	0.018726 (rank : 30)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P32067	Gene names	Ssb, Ss-b
Domain Architecture
Description	Lupus La protein homolog (La ribonucleoprotein) (La autoantigen homolog).

ATAD2_HUMAN
NC score	0.018622 (rank : 31)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	322	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

TBCD3_HUMAN
NC score	0.015325 (rank : 32)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

RINT1_HUMAN
NC score	0.015127 (rank : 33)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NUQ1, Q75MG9, Q75MH0, Q96IW8, Q9H229, Q9HAD9	Gene names	RINT1
Domain Architecture	No domain graphic available
Description	RAD50-interacting protein 1 (RAD50 interactor 1) (Protein RINT-1) (HsRINT-1).

DHB3_MOUSE
NC score	0.014202 (rank : 34)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	67	Shared Neighborhood Hits	2
SwissProt Accessions	P70385	Gene names	Hsd17b3, Edh17b3
Domain Architecture
Description	Estradiol 17-beta-dehydrogenase 3 (EC 1.1.1.62) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase).

RTP2_MOUSE
NC score	0.013907 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q80ZI2	Gene names	Rtp2, Gm605
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 2.

COA1_HUMAN
NC score	0.011766 (rank : 36)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

TAB2_MOUSE
NC score	0.010690 (rank : 37)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

CTRO_MOUSE
NC score	0.010676 (rank : 38)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	2344	Shared Neighborhood Hits	19
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

INVS_HUMAN
NC score	0.010560 (rank : 39)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	455	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

CTRO_HUMAN
NC score	0.010217 (rank : 40)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	2092	Shared Neighborhood Hits	19
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTND1_HUMAN
NC score	0.009268 (rank : 41)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).