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Network neighborhood for query Sequence : KR221_HUMAN

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KR221_HUMAN
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KR221_HUMAN
θ value	1.9326e-10 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

MEGF6_HUMAN
θ value	0.813845 (rank : 2)	NC score	0.077706 (rank : 7)
Query Neighborhood Hits	6	Target Neighborhood Hits	671	Shared Neighborhood Hits	6
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FBN1_HUMAN
θ value	4.03905 (rank : 3)	NC score	0.094620 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	557	Shared Neighborhood Hits	6
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	4.03905 (rank : 4)	NC score	0.094259 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	563	Shared Neighborhood Hits	6
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
θ value	4.03905 (rank : 5)	NC score	0.093224 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	549	Shared Neighborhood Hits	6
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP2_HUMAN
θ value	6.88961 (rank : 6)	NC score	0.057072 (rank : 39)
Query Neighborhood Hits	6	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

C1QR1_HUMAN
θ value	θ > 10 (rank : 7)	NC score	0.056384 (rank : 42)
Query Neighborhood Hits	6	Target Neighborhood Hits	493	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 8)	NC score	0.057812 (rank : 37)
Query Neighborhood Hits	6	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_MOUSE
θ value	θ > 10 (rank : 9)	NC score	0.050040 (rank : 80)
Query Neighborhood Hits	6	Target Neighborhood Hits	578	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CREL1_HUMAN
θ value	θ > 10 (rank : 10)	NC score	0.050478 (rank : 72)
Query Neighborhood Hits	6	Target Neighborhood Hits	441	Shared Neighborhood Hits	5
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 11)	NC score	0.050188 (rank : 76)
Query Neighborhood Hits	6	Target Neighborhood Hits	524	Shared Neighborhood Hits	5
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL8_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.051577 (rank : 64)
Query Neighborhood Hits	6	Target Neighborhood Hits	270	Shared Neighborhood Hits	5
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGF_HUMAN
θ value	θ > 10 (rank : 13)	NC score	0.055671 (rank : 46)
Query Neighborhood Hits	6	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 14)	NC score	0.055709 (rank : 45)
Query Neighborhood Hits	6	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBLN1_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.063778 (rank : 15)
Query Neighborhood Hits	6	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 16)	NC score	0.063762 (rank : 17)
Query Neighborhood Hits	6	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.062414 (rank : 21)
Query Neighborhood Hits	6	Target Neighborhood Hits	392	Shared Neighborhood Hits	5
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 18)	NC score	0.062329 (rank : 23)
Query Neighborhood Hits	6	Target Neighborhood Hits	505	Shared Neighborhood Hits	5
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.059942 (rank : 29)
Query Neighborhood Hits	6	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.059949 (rank : 28)
Query Neighborhood Hits	6	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.058155 (rank : 36)
Query Neighborhood Hits	6	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.058217 (rank : 34)
Query Neighborhood Hits	6	Target Neighborhood Hits	270	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.059782 (rank : 31)
Query Neighborhood Hits	6	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.059938 (rank : 30)
Query Neighborhood Hits	6	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN2_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.088255 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	560	Shared Neighborhood Hits	5
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.088593 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.052719 (rank : 58)
Query Neighborhood Hits	6	Target Neighborhood Hits	348	Shared Neighborhood Hits	5
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 28)	NC score	0.050423 (rank : 74)
Query Neighborhood Hits	6	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.055428 (rank : 47)
Query Neighborhood Hits	6	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.056741 (rank : 40)
Query Neighborhood Hits	6	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.051142 (rank : 68)
Query Neighborhood Hits	6	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.050164 (rank : 77)
Query Neighborhood Hits	6	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KR171_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.056167 (rank : 43)
Query Neighborhood Hits	6	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR211_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.055409 (rank : 48)
Query Neighborhood Hits	6	Target Neighborhood Hits	10	Shared Neighborhood Hits	1
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

KR511_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.050534 (rank : 71)
Query Neighborhood Hits	6	Target Neighborhood Hits	231	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA51_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.060848 (rank : 27)
Query Neighborhood Hits	6	Target Neighborhood Hits	288	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.056413 (rank : 41)
Query Neighborhood Hits	6	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.051567 (rank : 65)
Query Neighborhood Hits	6	Target Neighborhood Hits	270	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.059777 (rank : 32)
Query Neighborhood Hits	6	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.058207 (rank : 35)
Query Neighborhood Hits	6	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA59_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.054938 (rank : 51)
Query Neighborhood Hits	6	Target Neighborhood Hits	310	Shared Neighborhood Hits	5
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LCE1B_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.051880 (rank : 61)
Query Neighborhood Hits	6	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1F_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.053209 (rank : 55)
Query Neighborhood Hits	6	Target Neighborhood Hits	48	Shared Neighborhood Hits	1
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2B_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.056025 (rank : 44)
Query Neighborhood Hits	6	Target Neighborhood Hits	50	Shared Neighborhood Hits	1
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.050407 (rank : 75)
Query Neighborhood Hits	6	Target Neighborhood Hits	53	Shared Neighborhood Hits	1
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE3A_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.054115 (rank : 54)
Query Neighborhood Hits	6	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE4A_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.058592 (rank : 33)
Query Neighborhood Hits	6	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LTB1L_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.064609 (rank : 12)
Query Neighborhood Hits	6	Target Neighborhood Hits	553	Shared Neighborhood Hits	5
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.064624 (rank : 11)
Query Neighborhood Hits	6	Target Neighborhood Hits	514	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.064469 (rank : 13)
Query Neighborhood Hits	6	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.064911 (rank : 9)
Query Neighborhood Hits	6	Target Neighborhood Hits	479	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.063375 (rank : 20)
Query Neighborhood Hits	6	Target Neighborhood Hits	552	Shared Neighborhood Hits	5
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.063410 (rank : 19)
Query Neighborhood Hits	6	Target Neighborhood Hits	617	Shared Neighborhood Hits	5
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.064632 (rank : 10)
Query Neighborhood Hits	6	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.065176 (rank : 8)
Query Neighborhood Hits	6	Target Neighborhood Hits	475	Shared Neighborhood Hits	5
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.063772 (rank : 16)
Query Neighborhood Hits	6	Target Neighborhood Hits	607	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MATN2_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.061655 (rank : 24)
Query Neighborhood Hits	6	Target Neighborhood Hits	365	Shared Neighborhood Hits	5
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.062338 (rank : 22)
Query Neighborhood Hits	6	Target Neighborhood Hits	356	Shared Neighborhood Hits	5
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.054557 (rank : 52)
Query Neighborhood Hits	6	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.054397 (rank : 53)
Query Neighborhood Hits	6	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.055016 (rank : 49)
Query Neighborhood Hits	6	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.055009 (rank : 50)
Query Neighborhood Hits	6	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

NELL2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.050126 (rank : 79)
Query Neighborhood Hits	6	Target Neighborhood Hits	449	Shared Neighborhood Hits	5
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.051599 (rank : 63)
Query Neighborhood Hits	6	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.053163 (rank : 56)
Query Neighborhood Hits	6	Target Neighborhood Hits	916	Shared Neighborhood Hits	5
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.051793 (rank : 62)
Query Neighborhood Hits	6	Target Neighborhood Hits	1113	Shared Neighborhood Hits	5
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.052366 (rank : 59)
Query Neighborhood Hits	6	Target Neighborhood Hits	1069	Shared Neighborhood Hits	5
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.050127 (rank : 78)
Query Neighborhood Hits	6	Target Neighborhood Hits	1062	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.050659 (rank : 70)
Query Neighborhood Hits	6	Target Neighborhood Hits	975	Shared Neighborhood Hits	5
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PROS_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.051564 (rank : 66)
Query Neighborhood Hits	6	Target Neighborhood Hits	340	Shared Neighborhood Hits	5
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.052771 (rank : 57)
Query Neighborhood Hits	6	Target Neighborhood Hits	330	Shared Neighborhood Hits	5
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.063818 (rank : 14)
Query Neighborhood Hits	6	Target Neighborhood Hits	428	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.063651 (rank : 18)
Query Neighborhood Hits	6	Target Neighborhood Hits	442	Shared Neighborhood Hits	5
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SREC2_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.050814 (rank : 69)
Query Neighborhood Hits	6	Target Neighborhood Hits	605	Shared Neighborhood Hits	5
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.051505 (rank : 67)
Query Neighborhood Hits	6	Target Neighborhood Hits	645	Shared Neighborhood Hits	5
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SUSD1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.052201 (rank : 60)
Query Neighborhood Hits	6	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TRBM_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.061399 (rank : 26)
Query Neighborhood Hits	6	Target Neighborhood Hits	339	Shared Neighborhood Hits	5
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.061643 (rank : 25)
Query Neighborhood Hits	6	Target Neighborhood Hits	361	Shared Neighborhood Hits	5
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

VLDLR_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.050428 (rank : 73)
Query Neighborhood Hits	6	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZAN_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.057225 (rank : 38)
Query Neighborhood Hits	6	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

KR221_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.9326e-10 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

FBN1_HUMAN
NC score	0.094620 (rank : 2)	θ value	4.03905 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	557	Shared Neighborhood Hits	6
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
NC score	0.094259 (rank : 3)	θ value	4.03905 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	563	Shared Neighborhood Hits	6
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.093224 (rank : 4)	θ value	4.03905 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	549	Shared Neighborhood Hits	6
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
NC score	0.088593 (rank : 5)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	6	Target Neighborhood Hits	543	Shared Neighborhood Hits	5
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_HUMAN
NC score	0.088255 (rank : 6)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	6	Target Neighborhood Hits	560	Shared Neighborhood Hits	5
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MEGF6_HUMAN
NC score	0.077706 (rank : 7)	θ value	0.813845 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	671	Shared Neighborhood Hits	6
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LTBP3_MOUSE
NC score	0.065176 (rank : 8)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	6	Target Neighborhood Hits	475	Shared Neighborhood Hits	5
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1S_MOUSE
NC score	0.064911 (rank : 9)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	6	Target Neighborhood Hits	479	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
NC score	0.064632 (rank : 10)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	6	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTB1L_MOUSE
NC score	0.064624 (rank : 11)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	6	Target Neighborhood Hits	514	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.064609 (rank : 12)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	6	Target Neighborhood Hits	553	Shared Neighborhood Hits	5
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.064469 (rank : 13)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	6	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SCUB3_HUMAN
NC score	0.063818 (rank : 14)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	6	Target Neighborhood Hits	428	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBLN1_HUMAN
NC score	0.063778 (rank : 15)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	6	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LTBP4_MOUSE
NC score	0.063772 (rank : 16)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	6	Target Neighborhood Hits	607	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBLN1_MOUSE
NC score	0.063762 (rank : 17)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	6	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

SCUB3_MOUSE
NC score	0.063651 (rank : 18)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	6	Target Neighborhood Hits	442	Shared Neighborhood Hits	5
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTBP2_MOUSE
NC score	0.063410 (rank : 19)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	6	Target Neighborhood Hits	617	Shared Neighborhood Hits	5
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
NC score	0.063375 (rank : 20)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	6	Target Neighborhood Hits	552	Shared Neighborhood Hits	5
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN2_HUMAN
NC score	0.062414 (rank : 21)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	6	Target Neighborhood Hits	392	Shared Neighborhood Hits	5
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

MATN2_MOUSE
NC score	0.062338 (rank : 22)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	6	Target Neighborhood Hits	356	Shared Neighborhood Hits	5
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN2_MOUSE
NC score	0.062329 (rank : 23)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	6	Target Neighborhood Hits	505	Shared Neighborhood Hits	5
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

MATN2_HUMAN
NC score	0.061655 (rank : 24)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	6	Target Neighborhood Hits	365	Shared Neighborhood Hits	5
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

TRBM_MOUSE
NC score	0.061643 (rank : 25)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	6	Target Neighborhood Hits	361	Shared Neighborhood Hits	5
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_HUMAN
NC score	0.061399 (rank : 26)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	6	Target Neighborhood Hits	339	Shared Neighborhood Hits	5
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KRA51_HUMAN
NC score	0.060848 (rank : 27)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	6	Target Neighborhood Hits	288	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

FBLN3_MOUSE
NC score	0.059949 (rank : 28)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	6	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN3_HUMAN
NC score	0.059942 (rank : 29)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	6	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN5_MOUSE
NC score	0.059938 (rank : 30)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	6	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBLN5_HUMAN
NC score	0.059782 (rank : 31)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	6	Target Neighborhood Hits	329	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KRA56_HUMAN
NC score	0.059777 (rank : 32)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	6	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LCE4A_HUMAN
NC score	0.058592 (rank : 33)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	6	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

FBLN4_MOUSE
NC score	0.058217 (rank : 34)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	6	Target Neighborhood Hits	270	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

KRA57_HUMAN
NC score	0.058207 (rank : 35)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	6	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

FBLN4_HUMAN
NC score	0.058155 (rank : 36)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	6	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

C1QR1_MOUSE
NC score	0.057812 (rank : 37)	θ value	θ > 10 (rank : 8)
Query Neighborhood Hits	6	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

ZAN_MOUSE
NC score	0.057225 (rank : 38)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	6	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LRP2_HUMAN
NC score	0.057072 (rank : 39)	θ value	6.88961 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	573	Shared Neighborhood Hits	6
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

GRN_MOUSE
NC score	0.056741 (rank : 40)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	6	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KRA53_HUMAN
NC score	0.056413 (rank : 41)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	6	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

C1QR1_HUMAN
NC score	0.056384 (rank : 42)	θ value	θ > 10 (rank : 7)
Query Neighborhood Hits	6	Target Neighborhood Hits	493	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

KR171_HUMAN
NC score	0.056167 (rank : 43)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	6	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LCE2B_HUMAN
NC score	0.056025 (rank : 44)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	6	Target Neighborhood Hits	50	Shared Neighborhood Hits	1
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

EGF_MOUSE
NC score	0.055709 (rank : 45)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	6	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EGF_HUMAN
NC score	0.055671 (rank : 46)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	6	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

GRN_HUMAN
NC score	0.055428 (rank : 47)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	6	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KR211_HUMAN
NC score	0.055409 (rank : 48)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	6	Target Neighborhood Hits	10	Shared Neighborhood Hits	1
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

MATN4_HUMAN
NC score	0.055016 (rank : 49)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	6	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
NC score	0.055009 (rank : 50)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	6	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KRA59_HUMAN
NC score	0.054938 (rank : 51)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	6	Target Neighborhood Hits	310	Shared Neighborhood Hits	5
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MATN3_HUMAN
NC score	0.054557 (rank : 52)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	6	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
NC score	0.054397 (rank : 53)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	6	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LCE3A_HUMAN
NC score	0.054115 (rank : 54)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	6	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE1F_HUMAN
NC score	0.053209 (rank : 55)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	6	Target Neighborhood Hits	48	Shared Neighborhood Hits	1
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

NOTC1_MOUSE
NC score	0.053163 (rank : 56)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	6	Target Neighborhood Hits	916	Shared Neighborhood Hits	5
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PROS_MOUSE
NC score	0.052771 (rank : 57)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	6	Target Neighborhood Hits	330	Shared Neighborhood Hits	5
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_HUMAN
NC score	0.052719 (rank : 58)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	6	Target Neighborhood Hits	348	Shared Neighborhood Hits	5
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NOTC2_MOUSE
NC score	0.052366 (rank : 59)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	6	Target Neighborhood Hits	1069	Shared Neighborhood Hits	5
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SUSD1_HUMAN
NC score	0.052201 (rank : 60)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	6	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

LCE1B_HUMAN
NC score	0.051880 (rank : 61)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	6	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

NOTC2_HUMAN
NC score	0.051793 (rank : 62)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	6	Target Neighborhood Hits	1113	Shared Neighborhood Hits	5
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.051599 (rank : 63)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	6	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EGFL8_HUMAN
NC score	0.051577 (rank : 64)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	6	Target Neighborhood Hits	270	Shared Neighborhood Hits	5
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

KRA54_HUMAN
NC score	0.051567 (rank : 65)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	6	Target Neighborhood Hits	270	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

PROS_HUMAN
NC score	0.051564 (rank : 66)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	6	Target Neighborhood Hits	340	Shared Neighborhood Hits	5
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SREC_HUMAN
NC score	0.051505 (rank : 67)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	6	Target Neighborhood Hits	645	Shared Neighborhood Hits	5
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

HHIP_HUMAN
NC score	0.051142 (rank : 68)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	6	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

SREC2_MOUSE
NC score	0.050814 (rank : 69)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	6	Target Neighborhood Hits	605	Shared Neighborhood Hits	5
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NOTC3_MOUSE
NC score	0.050659 (rank : 70)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	6	Target Neighborhood Hits	975	Shared Neighborhood Hits	5
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

KR511_HUMAN
NC score	0.050534 (rank : 71)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	6	Target Neighborhood Hits	231	Shared Neighborhood Hits	5
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

CREL1_HUMAN
NC score	0.050478 (rank : 72)	θ value	θ > 10 (rank : 10)
Query Neighborhood Hits	6	Target Neighborhood Hits	441	Shared Neighborhood Hits	5
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

VLDLR_MOUSE
NC score	0.050428 (rank : 73)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	6	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

GAS6_MOUSE
NC score	0.050423 (rank : 74)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	6	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LCE2C_HUMAN
NC score	0.050407 (rank : 75)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	6	Target Neighborhood Hits	53	Shared Neighborhood Hits	1
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

CREL1_MOUSE
NC score	0.050188 (rank : 76)	θ value	θ > 10 (rank : 11)
Query Neighborhood Hits	6	Target Neighborhood Hits	524	Shared Neighborhood Hits	5
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

HHIP_MOUSE
NC score	0.050164 (rank : 77)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	6	Target Neighborhood Hits	219	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NOTC3_HUMAN
NC score	0.050127 (rank : 78)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	6	Target Neighborhood Hits	1062	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NELL2_HUMAN
NC score	0.050126 (rank : 79)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	6	Target Neighborhood Hits	449	Shared Neighborhood Hits	5
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CD248_MOUSE
NC score	0.050040 (rank : 80)	θ value	θ > 10 (rank : 9)
Query Neighborhood Hits	6	Target Neighborhood Hits	578	Shared Neighborhood Hits	5
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).