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Network neighborhood for query Sequence : ACE2_MOUSE

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ACE2_MOUSE
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ACE2_HUMAN
θ value	0 (rank : 1)	NC score	0.997971 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYF1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6	Gene names	ACE2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH).

ACE2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

ACE_HUMAN
θ value	2.26584e-152 (rank : 3)	NC score	0.922638 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ACET_HUMAN
θ value	8.0589e-150 (rank : 4)	NC score	0.933768 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_MOUSE
θ value	1.51984e-148 (rank : 5)	NC score	0.920704 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

ACET_MOUSE
θ value	1.28662e-147 (rank : 6)	NC score	0.933411 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P22967	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

TMM27_MOUSE
θ value	2.12192e-33 (rank : 7)	NC score	0.557798 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESG4, Q3UFF6	Gene names	Tmem27, Nx17
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

TMM27_HUMAN
θ value	1.99067e-23 (rank : 8)	NC score	0.528602 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBJ8, Q6UW07	Gene names	TMEM27
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

CAC1I_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.014894 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

HMMR_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.008558 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	1082	Shared Neighborhood Hits	4
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

XL3B_MOUSE
θ value	1.38821 (rank : 11)	NC score	0.023121 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	146	Shared Neighborhood Hits	2
SwissProt Accessions	Q61806, Q61244	Gene names	Xlr3b
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A (XLR-related protein A12).

ANR26_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.005697 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	1614	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CAC1G_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.011697 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	587	Shared Neighborhood Hits	3
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

KPCD1_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.000036 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	901	Shared Neighborhood Hits	2
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

PTPRT_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.003714 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

OR5I1_HUMAN
θ value	5.27518 (rank : 16)	NC score	-0.000890 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	671	Shared Neighborhood Hits	2
SwissProt Accessions	Q13606, Q6IEU4	Gene names	OR5I1, OLF1
Domain Architecture
Description	Olfactory receptor 5I1 (Olfactory receptor-like protein OLF1) (Olfactory receptor OR11-159).

HDAC1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.008733 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q13547, Q92534	Gene names	HDAC1, RPD3L1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC1_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.008731 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O09106, P97476	Gene names	Hdac1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

NPCL1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.008218 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

K2C8_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.001300 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	593	Shared Neighborhood Hits	4
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

Hits sorted by NC score

ACE2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

ACE2_HUMAN
NC score	0.997971 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYF1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6	Gene names	ACE2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH).

ACET_HUMAN
NC score	0.933768 (rank : 3)	θ value	8.0589e-150 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P22966	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACET_MOUSE
NC score	0.933411 (rank : 4)	θ value	1.28662e-147 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P22967	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, testis-specific isoform precursor (EC 3.4.15.1) (EC 3.2.1.-) (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin-converting enzyme, testis- specific isoform, soluble form].

ACE_HUMAN
NC score	0.922638 (rank : 5)	θ value	2.26584e-152 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P12821, Q53YX9, Q59GY8	Gene names	ACE, DCP, DCP1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD143 antigen) [Contains: Angiotensin-converting enzyme, somatic isoform, soluble form].

ACE_MOUSE
NC score	0.920704 (rank : 6)	θ value	1.51984e-148 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P09470, Q6GTS2	Gene names	Ace, Dcp1
Domain Architecture
Description	Angiotensin-converting enzyme, somatic isoform precursor (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) [Contains: Angiotensin- converting enzyme, somatic isoform, soluble form].

TMM27_MOUSE
NC score	0.557798 (rank : 7)	θ value	2.12192e-33 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESG4, Q3UFF6	Gene names	Tmem27, Nx17
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

TMM27_HUMAN
NC score	0.528602 (rank : 8)	θ value	1.99067e-23 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBJ8, Q6UW07	Gene names	TMEM27
Domain Architecture	No domain graphic available
Description	Collectrin precursor (Transmembrane protein 27).

XL3B_MOUSE
NC score	0.023121 (rank : 9)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	146	Shared Neighborhood Hits	2
SwissProt Accessions	Q61806, Q61244	Gene names	Xlr3b
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A (XLR-related protein A12).

CAC1I_HUMAN
NC score	0.014894 (rank : 10)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1G_HUMAN
NC score	0.011697 (rank : 11)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	587	Shared Neighborhood Hits	3
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

HDAC1_HUMAN
NC score	0.008733 (rank : 12)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q13547, Q92534	Gene names	HDAC1, RPD3L1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HDAC1_MOUSE
NC score	0.008731 (rank : 13)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O09106, P97476	Gene names	Hdac1
Domain Architecture
Description	Histone deacetylase 1 (HD1).

HMMR_HUMAN
NC score	0.008558 (rank : 14)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	1082	Shared Neighborhood Hits	4
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

NPCL1_MOUSE
NC score	0.008218 (rank : 15)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q6T3U4, Q5SVX1	Gene names	Npc1l1
Domain Architecture	No domain graphic available
Description	Niemann-Pick C1-like protein 1 precursor.

ANR26_HUMAN
NC score	0.005697 (rank : 16)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	1614	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

PTPRT_MOUSE
NC score	0.003714 (rank : 17)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

K2C8_HUMAN
NC score	0.001300 (rank : 18)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	593	Shared Neighborhood Hits	4
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

KPCD1_HUMAN
NC score	0.000036 (rank : 19)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	901	Shared Neighborhood Hits	2
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

OR5I1_HUMAN
NC score	-0.000890 (rank : 20)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	671	Shared Neighborhood Hits	2
SwissProt Accessions	Q13606, Q6IEU4	Gene names	OR5I1, OLF1
Domain Architecture
Description	Olfactory receptor 5I1 (Olfactory receptor-like protein OLF1) (Olfactory receptor OR11-159).