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Network neighborhood for query Sequence : ACY2_MOUSE

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ACY2_MOUSE
SwissProt Accessions	Q8R3P0, Q9D876, Q9DCE2, Q9JIN8	Gene names	Aspa
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ACY2_MOUSE
θ value	5.9214e-177 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3P0, Q9D876, Q9DCE2, Q9JIN8	Gene names	Aspa
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).

ACY2_HUMAN
θ value	7.52544e-156 (rank : 2)	NC score	0.997222 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P45381	Gene names	ASPA, ACY2, ASP
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).

ACY3_MOUSE
θ value	2.24094e-75 (rank : 3)	NC score	0.961758 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XE4, Q3UP59, Q9DD17	Gene names	Acy3, Aspa2
Domain Architecture
Description	Aspartoacylase-2 (EC 3.5.1.15) (Aminoacylase-3) (ACY-3) (Acylase III) (Hepatitis C virus core-binding protein 1) (HCBP1).

ACY3_HUMAN
θ value	3.34864e-71 (rank : 4)	NC score	0.959037 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HD9	Gene names	ACY3, ASPA2
Domain Architecture
Description	Aspartoacylase-2 (EC 3.5.1.15) (Aminoacylase-3) (ACY-3) (Acylase III) (Hepatitis C virus core-binding protein 1) (HCBP1).

P3C2A_MOUSE
θ value	0.0431538 (rank : 5)	NC score	0.030391 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

CP2C8_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.008102 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	P10632	Gene names	CYP2C8
Domain Architecture
Description	Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (P450 form 1) (P450 MP- 12/MP-20) (P450 IIC2) (S-mephenytoin 4-hydroxylase).

NCKPL_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.023397 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P55160	Gene names	NCKAP1L, HEM1
Domain Architecture	No domain graphic available
Description	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1).

SPTN2_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.004668 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	535	Shared Neighborhood Hits	2
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

Hits sorted by NC score

ACY2_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.9214e-177 (rank : 1)
Query Neighborhood Hits	8	Target Neighborhood Hits	8	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3P0, Q9D876, Q9DCE2, Q9JIN8	Gene names	Aspa
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).

ACY2_HUMAN
NC score	0.997222 (rank : 2)	θ value	7.52544e-156 (rank : 2)
Query Neighborhood Hits	8	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	P45381	Gene names	ASPA, ACY2, ASP
Domain Architecture
Description	Aspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2).

ACY3_MOUSE
NC score	0.961758 (rank : 3)	θ value	2.24094e-75 (rank : 3)
Query Neighborhood Hits	8	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q91XE4, Q3UP59, Q9DD17	Gene names	Acy3, Aspa2
Domain Architecture
Description	Aspartoacylase-2 (EC 3.5.1.15) (Aminoacylase-3) (ACY-3) (Acylase III) (Hepatitis C virus core-binding protein 1) (HCBP1).

ACY3_HUMAN
NC score	0.959037 (rank : 4)	θ value	3.34864e-71 (rank : 4)
Query Neighborhood Hits	8	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HD9	Gene names	ACY3, ASPA2
Domain Architecture
Description	Aspartoacylase-2 (EC 3.5.1.15) (Aminoacylase-3) (ACY-3) (Acylase III) (Hepatitis C virus core-binding protein 1) (HCBP1).

P3C2A_MOUSE
NC score	0.030391 (rank : 5)	θ value	0.0431538 (rank : 5)
Query Neighborhood Hits	8	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

NCKPL_HUMAN
NC score	0.023397 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	8	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P55160	Gene names	NCKAP1L, HEM1
Domain Architecture	No domain graphic available
Description	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1).

CP2C8_HUMAN
NC score	0.008102 (rank : 7)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	8	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	P10632	Gene names	CYP2C8
Domain Architecture
Description	Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (P450 form 1) (P450 MP- 12/MP-20) (P450 IIC2) (S-mephenytoin 4-hydroxylase).

SPTN2_HUMAN
NC score	0.004668 (rank : 8)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	8	Target Neighborhood Hits	535	Shared Neighborhood Hits	2
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).