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Network neighborhood for query Sequence : TCPZ_HUMAN

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TCPZ_HUMAN
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TCPW_HUMAN
θ value	0 (rank : 1)	NC score	0.993398 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPW_MOUSE
θ value	0 (rank : 2)	NC score	0.992466 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

TCPZ_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPZ_MOUSE
θ value	0 (rank : 4)	NC score	0.999131 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPG_MOUSE
θ value	1.96316e-71 (rank : 5)	NC score	0.935219 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPG_HUMAN
θ value	7.45998e-71 (rank : 6)	NC score	0.934831 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPA_HUMAN
θ value	6.76295e-64 (rank : 7)	NC score	0.938033 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPH_MOUSE
θ value	7.47731e-63 (rank : 8)	NC score	0.940107 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPA1_MOUSE
θ value	4.84666e-62 (rank : 9)	NC score	0.936048 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPD_MOUSE
θ value	4.84666e-62 (rank : 10)	NC score	0.939224 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPH_HUMAN
θ value	4.84666e-62 (rank : 11)	NC score	0.940314 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPD_HUMAN
θ value	8.26713e-62 (rank : 12)	NC score	0.938938 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPA2_MOUSE
θ value	1.07972e-61 (rank : 13)	NC score	0.936000 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPE_MOUSE
θ value	6.99855e-61 (rank : 14)	NC score	0.937082 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_HUMAN
θ value	4.53632e-60 (rank : 15)	NC score	0.937344 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPB_HUMAN
θ value	2.94719e-51 (rank : 16)	NC score	0.926746 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_MOUSE
θ value	4.25575e-50 (rank : 17)	NC score	0.925417 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPQ_HUMAN
θ value	4.41421e-39 (rank : 18)	NC score	0.908902 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPQ_MOUSE
θ value	4.41421e-39 (rank : 19)	NC score	0.908493 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

CH60_HUMAN
θ value	2.79066e-09 (rank : 20)	NC score	0.613745 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

BBS10_MOUSE
θ value	4.1701e-05 (rank : 21)	NC score	0.390945 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

CH60_MOUSE
θ value	4.1701e-05 (rank : 22)	NC score	0.599406 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

MKKS_MOUSE
θ value	4.1701e-05 (rank : 23)	NC score	0.437693 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

BBS10_HUMAN
θ value	7.1131e-05 (rank : 24)	NC score	0.431167 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

CP250_HUMAN
θ value	0.0961366 (rank : 25)	NC score	0.014279 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	1805	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

IF3A_MOUSE
θ value	0.21417 (rank : 26)	NC score	0.029157 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	871	Shared Neighborhood Hits	16
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF3A_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.028851 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	875	Shared Neighborhood Hits	17
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

GOGB1_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.010400 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	2297	Shared Neighborhood Hits	17
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYH2_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.008074 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	1491	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

HMMR_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.010235 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1082	Shared Neighborhood Hits	16
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

SMC2_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.011338 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	1405	Shared Neighborhood Hits	18
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TPR_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.011432 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	1921	Shared Neighborhood Hits	19
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCD91_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.013648 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	868	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CP250_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.011975 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	1583	Shared Neighborhood Hits	17
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYH3_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.006495 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	1660	Shared Neighborhood Hits	16
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TENS1_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.007407 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	400	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MYH13_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.006640 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	1504	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

TDRD3_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.014447 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

MAP4_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.004783 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TTC3_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.009890 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	664	Shared Neighborhood Hits	15
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

UBP8_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.004596 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	362	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

CCD39_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.009708 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	1026	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

UBP8_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.004921 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

FYV1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.173256 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	217	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.173790 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

MKKS_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.342680 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

Hits sorted by NC score

TCPZ_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPZ_MOUSE
NC score	0.999131 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPW_HUMAN
NC score	0.993398 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPW_MOUSE
NC score	0.992466 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

TCPH_HUMAN
NC score	0.940314 (rank : 5)	θ value	4.84666e-62 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
NC score	0.940107 (rank : 6)	θ value	7.47731e-63 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPD_MOUSE
NC score	0.939224 (rank : 7)	θ value	4.84666e-62 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPD_HUMAN
NC score	0.938938 (rank : 8)	θ value	8.26713e-62 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPA_HUMAN
NC score	0.938033 (rank : 9)	θ value	6.76295e-64 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPE_HUMAN
NC score	0.937344 (rank : 10)	θ value	4.53632e-60 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_MOUSE
NC score	0.937082 (rank : 11)	θ value	6.99855e-61 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPA1_MOUSE
NC score	0.936048 (rank : 12)	θ value	4.84666e-62 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPA2_MOUSE
NC score	0.936000 (rank : 13)	θ value	1.07972e-61 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPG_MOUSE
NC score	0.935219 (rank : 14)	θ value	1.96316e-71 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPG_HUMAN
NC score	0.934831 (rank : 15)	θ value	7.45998e-71 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPB_HUMAN
NC score	0.926746 (rank : 16)	θ value	2.94719e-51 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_MOUSE
NC score	0.925417 (rank : 17)	θ value	4.25575e-50 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPQ_HUMAN
NC score	0.908902 (rank : 18)	θ value	4.41421e-39 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPQ_MOUSE
NC score	0.908493 (rank : 19)	θ value	4.41421e-39 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

CH60_HUMAN
NC score	0.613745 (rank : 20)	θ value	2.79066e-09 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
NC score	0.599406 (rank : 21)	θ value	4.1701e-05 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

MKKS_MOUSE
NC score	0.437693 (rank : 22)	θ value	4.1701e-05 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

BBS10_HUMAN
NC score	0.431167 (rank : 23)	θ value	7.1131e-05 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

BBS10_MOUSE
NC score	0.390945 (rank : 24)	θ value	4.1701e-05 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

MKKS_HUMAN
NC score	0.342680 (rank : 25)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

FYV1_MOUSE
NC score	0.173790 (rank : 26)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.173256 (rank : 27)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	217	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

IF3A_MOUSE
NC score	0.029157 (rank : 28)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	871	Shared Neighborhood Hits	16
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IF3A_HUMAN
NC score	0.028851 (rank : 29)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	875	Shared Neighborhood Hits	17
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

TDRD3_HUMAN
NC score	0.014447 (rank : 30)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

CP250_HUMAN
NC score	0.014279 (rank : 31)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	1805	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CCD91_HUMAN
NC score	0.013648 (rank : 32)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	868	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CP250_MOUSE
NC score	0.011975 (rank : 33)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	1583	Shared Neighborhood Hits	17
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

TPR_HUMAN
NC score	0.011432 (rank : 34)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	1921	Shared Neighborhood Hits	19
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SMC2_HUMAN
NC score	0.011338 (rank : 35)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	1405	Shared Neighborhood Hits	18
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

GOGB1_HUMAN
NC score	0.010400 (rank : 36)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	2297	Shared Neighborhood Hits	17
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HMMR_HUMAN
NC score	0.010235 (rank : 37)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	1082	Shared Neighborhood Hits	16
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

TTC3_HUMAN
NC score	0.009890 (rank : 38)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	664	Shared Neighborhood Hits	15
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

CCD39_MOUSE
NC score	0.009708 (rank : 39)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	1026	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MYH2_HUMAN
NC score	0.008074 (rank : 40)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	1491	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

TENS1_HUMAN
NC score	0.007407 (rank : 41)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	400	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MYH13_HUMAN
NC score	0.006640 (rank : 42)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1504	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH3_HUMAN
NC score	0.006495 (rank : 43)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	1660	Shared Neighborhood Hits	16
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

UBP8_HUMAN
NC score	0.004921 (rank : 44)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	751	Shared Neighborhood Hits	15
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

MAP4_HUMAN
NC score	0.004783 (rank : 45)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

UBP8_MOUSE
NC score	0.004596 (rank : 46)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	362	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).