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Network neighborhood for query Sequence : TCPA1_MOUSE

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TCPA1_MOUSE
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TCPA1_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPA2_MOUSE
θ value	0 (rank : 2)	NC score	0.999735 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	28
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA_HUMAN
θ value	0 (rank : 3)	NC score	0.999714 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPH_MOUSE
θ value	6.73165e-80 (rank : 4)	NC score	0.962947 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPH_HUMAN
θ value	1.95861e-79 (rank : 5)	NC score	0.962764 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPB_MOUSE
θ value	1.26953e-78 (rank : 6)	NC score	0.961540 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_HUMAN
θ value	1.40363e-77 (rank : 7)	NC score	0.961363 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPG_HUMAN
θ value	1.11217e-74 (rank : 8)	NC score	0.947347 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPG_MOUSE
θ value	2.47765e-74 (rank : 9)	NC score	0.946990 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPD_MOUSE
θ value	1.22964e-73 (rank : 10)	NC score	0.959271 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPD_HUMAN
θ value	2.09745e-73 (rank : 11)	NC score	0.959038 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPE_HUMAN
θ value	2.73936e-73 (rank : 12)	NC score	0.957072 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_MOUSE
θ value	3.95564e-72 (rank : 13)	NC score	0.956202 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPQ_MOUSE
θ value	8.83269e-64 (rank : 14)	NC score	0.949117 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPQ_HUMAN
θ value	1.15359e-63 (rank : 15)	NC score	0.949186 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPZ_MOUSE
θ value	5.7252e-63 (rank : 16)	NC score	0.936709 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPZ_HUMAN
θ value	4.84666e-62 (rank : 17)	NC score	0.936048 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPW_HUMAN
θ value	1.07972e-61 (rank : 18)	NC score	0.934501 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPW_MOUSE
θ value	2.40537e-61 (rank : 19)	NC score	0.932894 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

CH60_HUMAN
θ value	7.34386e-10 (rank : 20)	NC score	0.630847 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
θ value	3.64472e-09 (rank : 21)	NC score	0.623154 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

MKKS_MOUSE
θ value	2.61198e-07 (rank : 22)	NC score	0.486683 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

BBS10_HUMAN
θ value	1.09739e-05 (rank : 23)	NC score	0.439950 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

BBS10_MOUSE
θ value	1.87187e-05 (rank : 24)	NC score	0.389389 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

MKKS_HUMAN
θ value	0.00102713 (rank : 25)	NC score	0.418449 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

3BHS3_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.013465 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P26150	Gene names	Hsd3b3
Domain Architecture	No domain graphic available
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type III (3Beta-HSD III) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

CN166_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.042924 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y224	Gene names	C14orf166
Domain Architecture	No domain graphic available
Description	Protein C14orf166.

CN166_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.026934 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQE8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf166 homolog.

MLH3_HUMAN
θ value	8.99809 (rank : 29)	NC score	0.010722 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

PACE1_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.005367 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

USH1C_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.004881 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	557	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

FYV1_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.158155 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.158269 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

Hits sorted by NC score

TCPA1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPA2_MOUSE
NC score	0.999735 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	28
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA_HUMAN
NC score	0.999714 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPH_MOUSE
NC score	0.962947 (rank : 4)	θ value	6.73165e-80 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPH_HUMAN
NC score	0.962764 (rank : 5)	θ value	1.95861e-79 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPB_MOUSE
NC score	0.961540 (rank : 6)	θ value	1.26953e-78 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_HUMAN
NC score	0.961363 (rank : 7)	θ value	1.40363e-77 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPD_MOUSE
NC score	0.959271 (rank : 8)	θ value	1.22964e-73 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPD_HUMAN
NC score	0.959038 (rank : 9)	θ value	2.09745e-73 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPE_HUMAN
NC score	0.957072 (rank : 10)	θ value	2.73936e-73 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_MOUSE
NC score	0.956202 (rank : 11)	θ value	3.95564e-72 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPQ_HUMAN
NC score	0.949186 (rank : 12)	θ value	1.15359e-63 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPQ_MOUSE
NC score	0.949117 (rank : 13)	θ value	8.83269e-64 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPG_HUMAN
NC score	0.947347 (rank : 14)	θ value	1.11217e-74 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPG_MOUSE
NC score	0.946990 (rank : 15)	θ value	2.47765e-74 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPZ_MOUSE
NC score	0.936709 (rank : 16)	θ value	5.7252e-63 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPZ_HUMAN
NC score	0.936048 (rank : 17)	θ value	4.84666e-62 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPW_HUMAN
NC score	0.934501 (rank : 18)	θ value	1.07972e-61 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPW_MOUSE
NC score	0.932894 (rank : 19)	θ value	2.40537e-61 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

CH60_HUMAN
NC score	0.630847 (rank : 20)	θ value	7.34386e-10 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
NC score	0.623154 (rank : 21)	θ value	3.64472e-09 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

MKKS_MOUSE
NC score	0.486683 (rank : 22)	θ value	2.61198e-07 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

BBS10_HUMAN
NC score	0.439950 (rank : 23)	θ value	1.09739e-05 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

MKKS_HUMAN
NC score	0.418449 (rank : 24)	θ value	0.00102713 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

BBS10_MOUSE
NC score	0.389389 (rank : 25)	θ value	1.87187e-05 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

FYV1_MOUSE
NC score	0.158269 (rank : 26)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.158155 (rank : 27)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

CN166_HUMAN
NC score	0.042924 (rank : 28)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y224	Gene names	C14orf166
Domain Architecture	No domain graphic available
Description	Protein C14orf166.

CN166_MOUSE
NC score	0.026934 (rank : 29)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQE8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf166 homolog.

3BHS3_MOUSE
NC score	0.013465 (rank : 30)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P26150	Gene names	Hsd3b3
Domain Architecture	No domain graphic available
Description	3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type III (3Beta-HSD III) [Includes: 3-beta-hydroxy-delta(5)-steroid dehydrogenase (EC 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (Progesterone reductase); Steroid delta-isomerase (EC 5.3.3.1) (Delta-5-3-ketosteroid isomerase)].

MLH3_HUMAN
NC score	0.010722 (rank : 31)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHC1, P49751, Q56DK9, Q9P292, Q9UHC0	Gene names	MLH3
Domain Architecture
Description	DNA mismatch repair protein Mlh3 (MutL protein homolog 3).

PACE1_MOUSE
NC score	0.005367 (rank : 32)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

USH1C_MOUSE
NC score	0.004881 (rank : 33)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	557	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).