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Network neighborhood for query Sequence : TCPD_HUMAN

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TCPD_HUMAN
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TCPD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPD_MOUSE
θ value	0 (rank : 2)	NC score	0.999511 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPE_HUMAN
θ value	6.7005e-96 (rank : 3)	NC score	0.973825 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_MOUSE
θ value	5.30912e-93 (rank : 4)	NC score	0.973318 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPG_HUMAN
θ value	3.81361e-83 (rank : 5)	NC score	0.955017 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPG_MOUSE
θ value	2.47191e-82 (rank : 6)	NC score	0.954968 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPH_HUMAN
θ value	2.31364e-80 (rank : 7)	NC score	0.966092 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
θ value	4.36332e-79 (rank : 8)	NC score	0.965553 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPA_HUMAN
θ value	3.23591e-74 (rank : 9)	NC score	0.959335 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPA1_MOUSE
θ value	2.09745e-73 (rank : 10)	NC score	0.959038 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPA2_MOUSE
θ value	7.97034e-73 (rank : 11)	NC score	0.959431 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPB_HUMAN
θ value	1.83746e-69 (rank : 12)	NC score	0.959119 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPB_MOUSE
θ value	1.19101e-68 (rank : 13)	NC score	0.958185 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPW_HUMAN
θ value	2.56992e-63 (rank : 14)	NC score	0.939762 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPQ_MOUSE
θ value	5.7252e-63 (rank : 15)	NC score	0.949514 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPQ_HUMAN
θ value	7.47731e-63 (rank : 16)	NC score	0.949542 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPZ_MOUSE
θ value	3.71096e-62 (rank : 17)	NC score	0.939667 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	40	Shared Neighborhood Hits	23
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPZ_HUMAN
θ value	8.26713e-62 (rank : 18)	NC score	0.938938 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPW_MOUSE
θ value	5.0155e-59 (rank : 19)	NC score	0.935688 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

CH60_HUMAN
θ value	1.52774e-15 (rank : 20)	NC score	0.673897 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
θ value	1.52774e-15 (rank : 21)	NC score	0.668251 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

MKKS_HUMAN
θ value	1.25267e-09 (rank : 22)	NC score	0.425184 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

BBS10_MOUSE
θ value	9.29e-05 (rank : 23)	NC score	0.379311 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

BBS10_HUMAN
θ value	0.000270298 (rank : 24)	NC score	0.429014 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

CASP_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.009615 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	1131	Shared Neighborhood Hits	6
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.009579 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	1574	Shared Neighborhood Hits	6
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CAD12_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.002849 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	P55289	Gene names	CDH12
Domain Architecture
Description	Cadherin-12 precursor (Brain-cadherin) (BR-cadherin) (N-cadherin 2) (Neural type cadherin 2).

CUTL1_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.010937 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	1620	Shared Neighborhood Hits	7
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RTN4_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.015078 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CASP_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.008254 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	1152	Shared Neighborhood Hits	6
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

TNKS2_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.003174 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PP4RL_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.016916 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

TBK1_MOUSE
θ value	6.88961 (rank : 33)	NC score	-0.002934 (rank : 38)
Query Neighborhood Hits	35	Target Neighborhood Hits	893	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).

CAD11_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.001462 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	P55287, Q15065, Q15066, Q9UQ93, Q9UQ94	Gene names	CDH11
Domain Architecture
Description	Cadherin-11 precursor (Osteoblast-cadherin) (OB-cadherin) (OSF-4).

LMNB1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.001382 (rank : 37)
Query Neighborhood Hits	35	Target Neighborhood Hits	714	Shared Neighborhood Hits	8
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

FYV1_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.168376 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.168079 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

MKKS_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.442421 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

Hits sorted by NC score

TCPD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

TCPD_MOUSE
NC score	0.999511 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPE_HUMAN
NC score	0.973825 (rank : 3)	θ value	6.7005e-96 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	P48643	Gene names	CCT5, CCTE, KIAA0098
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPE_MOUSE
NC score	0.973318 (rank : 4)	θ value	5.30912e-93 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P80316	Gene names	Cct5, Ccte
Domain Architecture
Description	T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon).

TCPH_HUMAN
NC score	0.966092 (rank : 5)	θ value	2.31364e-80 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

TCPH_MOUSE
NC score	0.965553 (rank : 6)	θ value	4.36332e-79 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P80313	Gene names	Cct7, Ccth
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta).

TCPA2_MOUSE
NC score	0.959431 (rank : 7)	θ value	7.97034e-73 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P11983	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha B (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1B) (TCP-1-B).

TCPA_HUMAN
NC score	0.959335 (rank : 8)	θ value	3.23591e-74 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P17987, Q15556, Q5TCM3	Gene names	CCT1, CCTA, TCP1
Domain Architecture
Description	T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha).

TCPB_HUMAN
NC score	0.959119 (rank : 9)	θ value	1.83746e-69 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P78371, Q6IAT3	Gene names	CCT2, 99D8.1, CCTB
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPA1_MOUSE
NC score	0.959038 (rank : 10)	θ value	2.09745e-73 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P11984	Gene names	Cct1, Ccta, Tcp1
Domain Architecture
Description	T-complex protein 1 subunit alpha A (TCP-1-alpha) (CCT-alpha) (Tailless complex polypeptide 1A) (TCP-1-A).

TCPB_MOUSE
NC score	0.958185 (rank : 11)	θ value	1.19101e-68 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P80314, Q9R1U0	Gene names	Cct2, Cctb
Domain Architecture
Description	T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta).

TCPG_HUMAN
NC score	0.955017 (rank : 12)	θ value	3.81361e-83 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

TCPG_MOUSE
NC score	0.954968 (rank : 13)	θ value	2.47191e-82 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P80318	Gene names	Cct3, Cctg
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Matricin) (mTRiC-P5).

TCPQ_HUMAN
NC score	0.949542 (rank : 14)	θ value	7.47731e-63 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	P50990	Gene names	CCT8, CCTQ, KIAA0002
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (NY-REN-15 antigen).

TCPQ_MOUSE
NC score	0.949514 (rank : 15)	θ value	5.7252e-63 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P42932	Gene names	Cct8, Cctq
Domain Architecture
Description	T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta).

TCPW_HUMAN
NC score	0.939762 (rank : 16)	θ value	2.56992e-63 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q92526, Q8TC34	Gene names	CCT6B
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (TCP-1- zeta-like) (CCT-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303).

TCPZ_MOUSE
NC score	0.939667 (rank : 17)	θ value	3.71096e-62 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	40	Shared Neighborhood Hits	23
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

TCPZ_HUMAN
NC score	0.938938 (rank : 18)	θ value	8.26713e-62 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPW_MOUSE
NC score	0.935688 (rank : 19)	θ value	5.0155e-59 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q61390, Q9R1U2	Gene names	Cct6b
Domain Architecture
Description	T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz- 2).

CH60_HUMAN
NC score	0.673897 (rank : 20)	θ value	1.52774e-15 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	P10809	Gene names	HSPD1, HSP60
Domain Architecture
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60).

CH60_MOUSE
NC score	0.668251 (rank : 21)	θ value	1.52774e-15 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P63038, P19226, P19227, P97602	Gene names	Hspd1, Hsp60
Domain Architecture	No domain graphic available
Description	60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (HSP-65).

MKKS_MOUSE
NC score	0.442421 (rank : 22)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JI70	Gene names	Mkks
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.

BBS10_HUMAN
NC score	0.429014 (rank : 23)	θ value	0.000270298 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAM1, Q96CW2, Q9H5D2	Gene names	BBS10, C12orf58
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein.

MKKS_HUMAN
NC score	0.425184 (rank : 24)	θ value	1.25267e-09 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NPJ1	Gene names	MKKS
Domain Architecture
Description	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet- Biedl syndrome 6 protein).

BBS10_MOUSE
NC score	0.379311 (rank : 25)	θ value	9.29e-05 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBI2	Gene names	Bbs10
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 10 protein homolog.

FYV1_HUMAN
NC score	0.168376 (rank : 26)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
NC score	0.168079 (rank : 27)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	35	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

PP4RL_HUMAN
NC score	0.016916 (rank : 28)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

RTN4_HUMAN
NC score	0.015078 (rank : 29)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	357	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CUTL1_MOUSE
NC score	0.010937 (rank : 30)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	1620	Shared Neighborhood Hits	7
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CASP_HUMAN
NC score	0.009615 (rank : 31)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	1131	Shared Neighborhood Hits	6
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
NC score	0.009579 (rank : 32)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	1574	Shared Neighborhood Hits	6
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CASP_MOUSE
NC score	0.008254 (rank : 33)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	1152	Shared Neighborhood Hits	6
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

TNKS2_HUMAN
NC score	0.003174 (rank : 34)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

CAD12_HUMAN
NC score	0.002849 (rank : 35)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	P55289	Gene names	CDH12
Domain Architecture
Description	Cadherin-12 precursor (Brain-cadherin) (BR-cadherin) (N-cadherin 2) (Neural type cadherin 2).

CAD11_HUMAN
NC score	0.001462 (rank : 36)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	P55287, Q15065, Q15066, Q9UQ93, Q9UQ94	Gene names	CDH11
Domain Architecture
Description	Cadherin-11 precursor (Osteoblast-cadherin) (OB-cadherin) (OSF-4).

LMNB1_HUMAN
NC score	0.001382 (rank : 37)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	714	Shared Neighborhood Hits	8
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

TBK1_MOUSE
NC score	-0.002934 (rank : 38)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	893	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUN2, Q9CT90, Q9DC03	Gene names	Tbk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (TANK-binding kinase 1) (T2K).