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Network neighborhood for query Sequence : BBC3_HUMAN

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BBC3_HUMAN
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BBC3_HUMAN
θ value	5.53243e-66 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).

BBC3_MOUSE
θ value	2.7521e-57 (rank : 2)	NC score	0.975080 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).

CRSP2_HUMAN
θ value	0.00665767 (rank : 3)	NC score	0.196070 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	380	Shared Neighborhood Hits	9
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

OGFR_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.038710 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	1582	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TSCOT_MOUSE
θ value	1.38821 (rank : 5)	NC score	0.051888 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CA03, Q9D3J2, Q9JLQ3	Gene names	Tscot
Domain Architecture	No domain graphic available
Description	Thymic stromal cotransporter protein.

PINK1_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.032239 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	741	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

EP400_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.024531 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

NRX2A_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.018787 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	614	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PINK1_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.028014 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	726	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

SSBP4_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.026177 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	753	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

NCOA3_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.020202 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

AMPH_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.021541 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

CECR2_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.021117 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	543	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

MEF2B_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.019836 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

CT151_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.052893 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

CT165_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.046057 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BR10	Gene names	C20orf165
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf165.

DAB2P_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.030888 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

SETBP_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.018925 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ZN687_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.005620 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	913	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

Hits sorted by NC score

BBC3_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.53243e-66 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).

BBC3_MOUSE
NC score	0.975080 (rank : 2)	θ value	2.7521e-57 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).

CRSP2_HUMAN
NC score	0.196070 (rank : 3)	θ value	0.00665767 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	380	Shared Neighborhood Hits	9
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CT151_HUMAN
NC score	0.052893 (rank : 4)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

TSCOT_MOUSE
NC score	0.051888 (rank : 5)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CA03, Q9D3J2, Q9JLQ3	Gene names	Tscot
Domain Architecture	No domain graphic available
Description	Thymic stromal cotransporter protein.

CT165_HUMAN
NC score	0.046057 (rank : 6)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BR10	Gene names	C20orf165
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf165.

OGFR_HUMAN
NC score	0.038710 (rank : 7)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	1582	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PINK1_HUMAN
NC score	0.032239 (rank : 8)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	741	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

DAB2P_MOUSE
NC score	0.030888 (rank : 9)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

PINK1_MOUSE
NC score	0.028014 (rank : 10)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	726	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

SSBP4_HUMAN
NC score	0.026177 (rank : 11)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	753	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

EP400_MOUSE
NC score	0.024531 (rank : 12)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

AMPH_MOUSE
NC score	0.021541 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

CECR2_HUMAN
NC score	0.021117 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	543	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

NCOA3_HUMAN
NC score	0.020202 (rank : 15)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

MEF2B_MOUSE
NC score	0.019836 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

SETBP_MOUSE
NC score	0.018925 (rank : 17)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

NRX2A_HUMAN
NC score	0.018787 (rank : 18)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	614	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ZN687_MOUSE
NC score	0.005620 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	913	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.