Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : TYRP1_MOUSE

For an explanation of this page, click here

TYRP1_MOUSE
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TYRP1_HUMAN
θ value	0 (rank : 1)	NC score	0.995646 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

TYRP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).

TYRP2_HUMAN
θ value	1.05497e-141 (rank : 3)	NC score	0.973992 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	P40126	Gene names	DCT, TYRP2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2).

TYRP2_MOUSE
θ value	3.39372e-140 (rank : 4)	NC score	0.975112 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P29812	Gene names	Dct, Tyrp-2, Tyrp2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) (SLATY locus protein).

TYRO_MOUSE
θ value	2.00813e-108 (rank : 5)	NC score	0.960280 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

TYRO_HUMAN
θ value	1.30163e-107 (rank : 6)	NC score	0.959220 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

SREC2_MOUSE
θ value	0.0330416 (rank : 7)	NC score	0.077614 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	605	Shared Neighborhood Hits	38
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAB2_MOUSE
θ value	0.125558 (rank : 8)	NC score	0.068721 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	528	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

NOTC4_HUMAN
θ value	0.279714 (rank : 9)	NC score	0.043887 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	905	Shared Neighborhood Hits	36
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	0.365318 (rank : 10)	NC score	0.046173 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	872	Shared Neighborhood Hits	36
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SREC2_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.075044 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMA4_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.056291 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	708	Shared Neighborhood Hits	36
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB2_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.065103 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	722	Shared Neighborhood Hits	36
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMA5_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.067957 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	828	Shared Neighborhood Hits	38
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

STAB1_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.076209 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	546	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TENA_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.054468 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	596	Shared Neighborhood Hits	40
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

STAB2_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.067677 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	534	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAMA5_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.067995 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	976	Shared Neighborhood Hits	39
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC1_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.053604 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	856	Shared Neighborhood Hits	38
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

STAB1_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.079842 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	566	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TENA_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.050857 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	631	Shared Neighborhood Hits	39
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

JAG1_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.046277 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	518	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DDR1_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.001718 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	819	Shared Neighborhood Hits	3
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

HUNK_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.000523 (rank : 49)
Query Neighborhood Hits	43	Target Neighborhood Hits	884	Shared Neighborhood Hits	3
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

LAMB2_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.064583 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	692	Shared Neighborhood Hits	36
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

PGBM_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.041447 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	1113	Shared Neighborhood Hits	38
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.043341 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	1073	Shared Neighborhood Hits	38
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TENX_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.045540 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	789	Shared Neighborhood Hits	37
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LAMC1_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.049126 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	922	Shared Neighborhood Hits	37
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.065925 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	645	Shared Neighborhood Hits	37
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

JAG1_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.043375 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	514	Shared Neighborhood Hits	35
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

FGL2_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.013715 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

LAMA4_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.051716 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	584	Shared Neighborhood Hits	35
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NTNG1_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.048845 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	247	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.048814 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	246	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

MEGF9_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.049844 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NOTC2_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.040434 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	1113	Shared Neighborhood Hits	37
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LAMA1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.049648 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	804	Shared Neighborhood Hits	35
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.055375 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	838	Shared Neighborhood Hits	39
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NOTC1_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.042910 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	906	Shared Neighborhood Hits	37
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.044130 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	916	Shared Neighborhood Hits	38
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.040341 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	1069	Shared Neighborhood Hits	37
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.039658 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	975	Shared Neighborhood Hits	36
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

KR171_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.051365 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA51_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.055011 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	288	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA55_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.051283 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	257	Shared Neighborhood Hits	30
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LAMC3_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.053774 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	588	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NAGPA_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.070476 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	282	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.064942 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	308	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

Hits sorted by NC score

TYRP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P07147	Gene names	Tyrp1, Tyrp-1
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Brown locus protein).

TYRP1_HUMAN
NC score	0.995646 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	P17643, P78468, P78469, Q13721, Q15679	Gene names	TYRP1, CAS2, TYRP, TYRRP
Domain Architecture
Description	5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (EC 1.14.18.-) (DHICA oxidase) (Tyrosinase-related protein 1) (TRP-1) (TRP1) (TRP) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75).

TYRP2_MOUSE
NC score	0.975112 (rank : 3)	θ value	3.39372e-140 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P29812	Gene names	Dct, Tyrp-2, Tyrp2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) (SLATY locus protein).

TYRP2_HUMAN
NC score	0.973992 (rank : 4)	θ value	1.05497e-141 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	P40126	Gene names	DCT, TYRP2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2).

TYRO_MOUSE
NC score	0.960280 (rank : 5)	θ value	2.00813e-108 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

TYRO_HUMAN
NC score	0.959220 (rank : 6)	θ value	1.30163e-107 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

STAB1_MOUSE
NC score	0.079842 (rank : 7)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	566	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SREC2_MOUSE
NC score	0.077614 (rank : 8)	θ value	0.0330416 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	605	Shared Neighborhood Hits	38
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAB1_HUMAN
NC score	0.076209 (rank : 9)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	546	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

SREC2_HUMAN
NC score	0.075044 (rank : 10)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NAGPA_HUMAN
NC score	0.070476 (rank : 11)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	282	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

STAB2_MOUSE
NC score	0.068721 (rank : 12)	θ value	0.125558 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	528	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LAMA5_HUMAN
NC score	0.067995 (rank : 13)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	976	Shared Neighborhood Hits	39
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
NC score	0.067957 (rank : 14)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	828	Shared Neighborhood Hits	38
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

STAB2_HUMAN
NC score	0.067677 (rank : 15)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	534	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SREC_HUMAN
NC score	0.065925 (rank : 16)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	645	Shared Neighborhood Hits	37
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMB2_MOUSE
NC score	0.065103 (rank : 17)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	722	Shared Neighborhood Hits	36
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NAGPA_MOUSE
NC score	0.064942 (rank : 18)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	43	Target Neighborhood Hits	308	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMB2_HUMAN
NC score	0.064583 (rank : 19)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	692	Shared Neighborhood Hits	36
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA4_HUMAN
NC score	0.056291 (rank : 20)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	708	Shared Neighborhood Hits	36
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA1_MOUSE
NC score	0.055375 (rank : 21)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	838	Shared Neighborhood Hits	39
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KRA51_HUMAN
NC score	0.055011 (rank : 22)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	288	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

TENA_MOUSE
NC score	0.054468 (rank : 23)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	596	Shared Neighborhood Hits	40
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LAMC3_HUMAN
NC score	0.053774 (rank : 24)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	588	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC1_MOUSE
NC score	0.053604 (rank : 25)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	856	Shared Neighborhood Hits	38
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA4_MOUSE
NC score	0.051716 (rank : 26)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	584	Shared Neighborhood Hits	35
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KR171_HUMAN
NC score	0.051365 (rank : 27)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA55_HUMAN
NC score	0.051283 (rank : 28)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	257	Shared Neighborhood Hits	30
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

TENA_HUMAN
NC score	0.050857 (rank : 29)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	631	Shared Neighborhood Hits	39
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

MEGF9_MOUSE
NC score	0.049844 (rank : 30)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	896	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA1_HUMAN
NC score	0.049648 (rank : 31)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	804	Shared Neighborhood Hits	35
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_HUMAN
NC score	0.049126 (rank : 32)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	922	Shared Neighborhood Hits	37
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NTNG1_HUMAN
NC score	0.048845 (rank : 33)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	247	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
NC score	0.048814 (rank : 34)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	246	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

JAG1_MOUSE
NC score	0.046277 (rank : 35)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	518	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC4_MOUSE
NC score	0.046173 (rank : 36)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	872	Shared Neighborhood Hits	36
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

TENX_HUMAN
NC score	0.045540 (rank : 37)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	789	Shared Neighborhood Hits	37
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NOTC1_MOUSE
NC score	0.044130 (rank : 38)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	916	Shared Neighborhood Hits	38
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_HUMAN
NC score	0.043887 (rank : 39)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	905	Shared Neighborhood Hits	36
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG1_HUMAN
NC score	0.043375 (rank : 40)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	514	Shared Neighborhood Hits	35
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

PGBM_MOUSE
NC score	0.043341 (rank : 41)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	1073	Shared Neighborhood Hits	38
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NOTC1_HUMAN
NC score	0.042910 (rank : 42)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	906	Shared Neighborhood Hits	37
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PGBM_HUMAN
NC score	0.041447 (rank : 43)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	1113	Shared Neighborhood Hits	38
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NOTC2_HUMAN
NC score	0.040434 (rank : 44)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1113	Shared Neighborhood Hits	37
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.040341 (rank : 45)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	1069	Shared Neighborhood Hits	37
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_MOUSE
NC score	0.039658 (rank : 46)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	975	Shared Neighborhood Hits	36
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FGL2_MOUSE
NC score	0.013715 (rank : 47)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

DDR1_HUMAN
NC score	0.001718 (rank : 48)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	819	Shared Neighborhood Hits	3
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

HUNK_HUMAN
NC score	0.000523 (rank : 49)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	884	Shared Neighborhood Hits	3
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).