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Network neighborhood for query Sequence : IF2M_HUMAN

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IF2M_HUMAN
SwissProt Accessions	P46199	Gene names	MTIF2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IF2M_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P46199	Gene names	MTIF2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

IF2M_MOUSE
θ value	0 (rank : 2)	NC score	0.956239 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	183	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

IF2P_HUMAN
θ value	3.39556e-23 (rank : 3)	NC score	0.333365 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	889	Shared Neighborhood Hits	35
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SELB_MOUSE
θ value	5.25075e-16 (rank : 4)	NC score	0.564673 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JHW4	Gene names	Eefsec, Selb
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB).

SELB_HUMAN
θ value	1.58096e-12 (rank : 5)	NC score	0.529450 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P57772	Gene names	EEFSEC, SELB
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific).

EFTU_MOUSE
θ value	1.133e-10 (rank : 6)	NC score	0.518035 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BFR5, Q6P919	Gene names	Tufm
Domain Architecture	No domain graphic available
Description	Elongation factor Tu, mitochondrial precursor.

EFTU_HUMAN
θ value	1.47974e-10 (rank : 7)	NC score	0.519623 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	P49411, O15276	Gene names	TUFM
Domain Architecture
Description	Elongation factor Tu, mitochondrial precursor (EF-Tu) (P43).

HBS1L_MOUSE
θ value	4.76016e-09 (rank : 8)	NC score	0.448382 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

HBS1L_HUMAN
θ value	3.08544e-08 (rank : 9)	NC score	0.444049 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y450, Q5T7G3, Q8NDW9, Q9UPW3	Gene names	HBS1L, HBS1, KIAA1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein (ERFS).

U5S1_HUMAN
θ value	1.99992e-07 (rank : 10)	NC score	0.388537 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q15029, Q9BUR0	Gene names	EFTUD2, KIAA0031, SNRP116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2) (hSNU114).

U5S1_MOUSE
θ value	1.99992e-07 (rank : 11)	NC score	0.388406 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

EFG1_MOUSE
θ value	4.45536e-07 (rank : 12)	NC score	0.426310 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K0D5, Q921D6, Q924I0	Gene names	Gfm1, Efg, Efg1, Gfm
Domain Architecture
Description	Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1).

GSPT1_MOUSE
θ value	4.45536e-07 (rank : 13)	NC score	0.433397 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R050, O88179	Gene names	Gspt1
Domain Architecture
Description	G1 to S phase transition protein 1 homolog.

EFG1_HUMAN
θ value	9.92553e-07 (rank : 14)	NC score	0.424849 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RP9, Q96T39	Gene names	GFM1, EFG, EFG1, GFM
Domain Architecture
Description	Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1).

GSPT1_HUMAN
θ value	1.29631e-06 (rank : 15)	NC score	0.429370 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P15170	Gene names	GSPT1
Domain Architecture
Description	G1 to S phase transition protein 1 homolog (GTP-binding protein GST1- HS).

EF2_MOUSE
θ value	1.09739e-05 (rank : 16)	NC score	0.378624 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P58252, Q544E4	Gene names	Eef2
Domain Architecture
Description	Elongation factor 2 (EF-2).

EFG2_HUMAN
θ value	1.09739e-05 (rank : 17)	NC score	0.418780 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q969S9, Q8WYI0	Gene names	GFM2, EFG2
Domain Architecture
Description	Elongation factor G 2, mitochondrial precursor (mEF-G 2) (Elongation factor G2).

EFG2_MOUSE
θ value	1.09739e-05 (rank : 18)	NC score	0.423059 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R2Q4	Gene names	Gfm2, Efg2
Domain Architecture
Description	Elongation factor G 2, mitochondrial precursor (mEF-G 2) (Elongation factor G2).

EF1A2_HUMAN
θ value	1.87187e-05 (rank : 19)	NC score	0.439579 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q05639, P54266	Gene names	EEF1A2, EEF1AL, STN
Domain Architecture
Description	Elongation factor 1-alpha 2 (EF-1-alpha-2) (Elongation factor 1 A-2) (eEF1A-2) (Statin S1).

EF1A2_MOUSE
θ value	1.87187e-05 (rank : 20)	NC score	0.439572 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	P62631, P27706	Gene names	Eef1a2, Eef1al, Stn
Domain Architecture	No domain graphic available
Description	Elongation factor 1-alpha 2 (EF-1-alpha-2) (Elongation factor 1 A-2) (eEF1A-2) (Statin S1).

EF2_HUMAN
θ value	2.44474e-05 (rank : 21)	NC score	0.373541 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P13639	Gene names	EEF2, EF2
Domain Architecture
Description	Elongation factor 2 (EF-2).

EF1A1_HUMAN
θ value	5.44631e-05 (rank : 22)	NC score	0.431817 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P68104, P04719, P04720	Gene names	EEF1A1, EEF1A, EF1A
Domain Architecture	No domain graphic available
Description	Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu).

EF1A1_MOUSE
θ value	5.44631e-05 (rank : 23)	NC score	0.431765 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P10126, Q61511, Q6ZWN2, Q8BMB8, Q8BVS8, Q99KU5	Gene names	Eef1a1, Eef1a
Domain Architecture
Description	Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu).

HIP1_HUMAN
θ value	0.00869519 (rank : 24)	NC score	0.034519 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	1016	Shared Neighborhood Hits	14
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

RASD1_MOUSE
θ value	0.0563607 (rank : 25)	NC score	0.056590 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	241	Shared Neighborhood Hits	19
SwissProt Accessions	O35626	Gene names	Rasd1, Dexras1
Domain Architecture
Description	Dexamethasone-induced Ras-related protein 1.

ARL3_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.037434 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	257	Shared Neighborhood Hits	12
SwissProt Accessions	P36405	Gene names	ARL3, ARFL3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

IF2G_HUMAN
θ value	0.125558 (rank : 27)	NC score	0.259916 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P41091	Gene names	EIF2S3, EIF2G
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma).

IF2G_MOUSE
θ value	0.125558 (rank : 28)	NC score	0.259910 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0N1	Gene names	Eif2s3x
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 3, X-linked (Eukaryotic translation initiation factor 2 subunit gamma, X-linked) (eIF-2-gamma X).

IF2H_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.263619 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0N2	Gene names	Eif2s3y
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 3, Y-linked (Eukaryotic translation initiation factor 2 subunit gamma, Y-linked) (eIF-2-gamma Y).

ARL3_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.036923 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	258	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WUL7	Gene names	Arl3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

RASD1_HUMAN
θ value	0.163984 (rank : 31)	NC score	0.052732 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y272, Q9NYB4	Gene names	RASD1, AGS1, DEXRAS1
Domain Architecture
Description	Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1).

RASH_MOUSE
θ value	0.163984 (rank : 32)	NC score	0.047187 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	257	Shared Neighborhood Hits	20
SwissProt Accessions	Q61411, Q80WD2	Gene names	Hras1, Hras
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

ARL11_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.052875 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q969Q4	Gene names	ARL11, ARLTS1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1).

CCD91_HUMAN
θ value	0.279714 (rank : 34)	NC score	0.044908 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	868	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

AR13B_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.051033 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	528	Shared Neighborhood Hits	12
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

IMDH1_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.049515 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P20839, Q8N194, Q96NU2	Gene names	IMPDH1, IMPD1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

RASH_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.044818 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	P01112, Q14080, Q6FHV9	Gene names	HRAS, HRAS1
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

RASK_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.044155 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	P01116, P01118, Q96D10	Gene names	KRAS, KRAS2, RASK2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

RASK_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.044019 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	P32883, P04200, P08643	Gene names	Kras, Kras2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

IMDH1_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.043187 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P50096	Gene names	Impdh1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

RASE_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.046142 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z444	Gene names	ERAS, HRAS2, HRASP
Domain Architecture	No domain graphic available
Description	GTPase ERas precursor (E-Ras) (Embryonic stem cell-expressed Ras).

SVIL_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.020271 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	439	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

AL3A1_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.022376 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

STMN2_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.034026 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.034026 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

AR13B_MOUSE
θ value	1.81305 (rank : 46)	NC score	0.039050 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	245	Shared Neighborhood Hits	14
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

MPP5_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.011156 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

RASN_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.041633 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	P01111, Q14971, Q15104, Q15282	Gene names	NRAS
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RASN_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.041646 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P08556	Gene names	Nras
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

SRPRB_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.039257 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P47758, Q544X9, Q9D872	Gene names	Srprb
Domain Architecture
Description	Signal recognition particle receptor subunit beta (SR-beta).

AL3A2_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.021269 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P47740	Gene names	Aldh3a2, Ahd-3, Ahd3, Aldh3, Aldh4
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

RAB36_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.023586 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	264	Shared Neighborhood Hits	21
SwissProt Accessions	O95755, Q7Z4A9, Q9UHP5	Gene names	RAB36
Domain Architecture
Description	Ras-related protein Rab-36.

VPS16_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.031535 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H269, Q5JUB1, Q8WU31, Q96EE7, Q96N92, Q9H1Q4, Q9H1Q5	Gene names	VPS16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (hVPS16).

ERAL_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.032594 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

GLU2B_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.025177 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	377	Shared Neighborhood Hits	10
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

BCLF1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.020409 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BPA1_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.008795 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	1477	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

NUMA1_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.014212 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	1523	Shared Neighborhood Hits	20
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

SH24A_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.023997 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

DGKK_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.013057 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	378	Shared Neighborhood Hits	4
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

KRHB1_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.004857 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	461	Shared Neighborhood Hits	8
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

NEK11_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.000755 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	1043	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

RASM_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.036088 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	250	Shared Neighborhood Hits	21
SwissProt Accessions	O14807, Q86WX8	Gene names	MRAS, RRAS3
Domain Architecture
Description	Ras-related protein M-Ras (Ras-related protein R-Ras3).

RASM_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.036290 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	251	Shared Neighborhood Hits	22
SwissProt Accessions	O08989	Gene names	Mras, Xras
Domain Architecture
Description	Ras-related protein M-Ras (Ras-related protein R-Ras3) (Muscle and microspikes Ras) (X-Ras).

RHES_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.045110 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	Q96D21, O95520, Q5THY8	Gene names	RASD2, TEM2
Domain Architecture
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2).

RHES_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.045562 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	P63032, Q9WVD3	Gene names	Rasd2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum).

TLN1_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.021572 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.021477 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

KRHB6_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.004490 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

PCNT_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.013231 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	1551	Shared Neighborhood Hits	14
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RAP1A_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.034814 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	P62834, P10113	Gene names	RAP1A, KREV1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rap-1A precursor (GTP-binding protein smg-p21A) (Ras-related protein Krev-1) (C21KG) (G-22K).

RAP1A_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.034814 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	P62835, P10113	Gene names	Rap1a, Krev-1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rap-1A precursor (Ras-related protein Krev-1).

SRPRB_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.046407 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5M8, Q8N2D8	Gene names	SRPRB
Domain Architecture
Description	Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1).

AL3A2_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.017946 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P51648, Q93011, Q96J37	Gene names	ALDH3A2, ALDH10, FALDH
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

CHD1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.003444 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	337	Shared Neighborhood Hits	4
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

GBP1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.010010 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	339	Shared Neighborhood Hits	10
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

KIF5C_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.005883 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

VPS16_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.024816 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q920Q4, Q8R3C3, Q99KZ4	Gene names	Vps16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (mVPS16).

GTPB1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.180846 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	O00178, Q6IC67	Gene names	GTPBP1
Domain Architecture
Description	GTP-binding protein 1 (G-protein 1) (GP-1) (GP1).

GTPB1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.179462 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	O08582, Q3UD96, Q3UGW6, Q545R1, Q80ZY5	Gene names	Gtpbp1, Gtpbp
Domain Architecture
Description	GTP-binding protein 1 (G-protein 1) (GP-1) (GP1).

GTPB2_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.159291 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BX10, Q5T7E8, Q8ND84, Q8TAH7, Q8WUA5, Q9HCS9, Q9NRU4, Q9NX60	Gene names	GTPBP2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2.

GTPB2_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.158866 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UJK4, Q9EST7, Q9JIX7	Gene names	Gtpbp2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2 (GTP-binding-like protein 2).

Hits sorted by NC score

IF2M_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P46199	Gene names	MTIF2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

IF2M_MOUSE
NC score	0.956239 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	183	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

SELB_MOUSE
NC score	0.564673 (rank : 3)	θ value	5.25075e-16 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JHW4	Gene names	Eefsec, Selb
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB).

SELB_HUMAN
NC score	0.529450 (rank : 4)	θ value	1.58096e-12 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P57772	Gene names	EEFSEC, SELB
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific).

EFTU_HUMAN
NC score	0.519623 (rank : 5)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	P49411, O15276	Gene names	TUFM
Domain Architecture
Description	Elongation factor Tu, mitochondrial precursor (EF-Tu) (P43).

EFTU_MOUSE
NC score	0.518035 (rank : 6)	θ value	1.133e-10 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BFR5, Q6P919	Gene names	Tufm
Domain Architecture	No domain graphic available
Description	Elongation factor Tu, mitochondrial precursor.

HBS1L_MOUSE
NC score	0.448382 (rank : 7)	θ value	4.76016e-09 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

HBS1L_HUMAN
NC score	0.444049 (rank : 8)	θ value	3.08544e-08 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y450, Q5T7G3, Q8NDW9, Q9UPW3	Gene names	HBS1L, HBS1, KIAA1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein (ERFS).

EF1A2_HUMAN
NC score	0.439579 (rank : 9)	θ value	1.87187e-05 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q05639, P54266	Gene names	EEF1A2, EEF1AL, STN
Domain Architecture
Description	Elongation factor 1-alpha 2 (EF-1-alpha-2) (Elongation factor 1 A-2) (eEF1A-2) (Statin S1).

EF1A2_MOUSE
NC score	0.439572 (rank : 10)	θ value	1.87187e-05 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	P62631, P27706	Gene names	Eef1a2, Eef1al, Stn
Domain Architecture	No domain graphic available
Description	Elongation factor 1-alpha 2 (EF-1-alpha-2) (Elongation factor 1 A-2) (eEF1A-2) (Statin S1).

GSPT1_MOUSE
NC score	0.433397 (rank : 11)	θ value	4.45536e-07 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R050, O88179	Gene names	Gspt1
Domain Architecture
Description	G1 to S phase transition protein 1 homolog.

EF1A1_HUMAN
NC score	0.431817 (rank : 12)	θ value	5.44631e-05 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P68104, P04719, P04720	Gene names	EEF1A1, EEF1A, EF1A
Domain Architecture	No domain graphic available
Description	Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu).

EF1A1_MOUSE
NC score	0.431765 (rank : 13)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P10126, Q61511, Q6ZWN2, Q8BMB8, Q8BVS8, Q99KU5	Gene names	Eef1a1, Eef1a
Domain Architecture
Description	Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor 1 A-1) (eEF1A-1) (Elongation factor Tu) (EF-Tu).

GSPT1_HUMAN
NC score	0.429370 (rank : 14)	θ value	1.29631e-06 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P15170	Gene names	GSPT1
Domain Architecture
Description	G1 to S phase transition protein 1 homolog (GTP-binding protein GST1- HS).

EFG1_MOUSE
NC score	0.426310 (rank : 15)	θ value	4.45536e-07 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K0D5, Q921D6, Q924I0	Gene names	Gfm1, Efg, Efg1, Gfm
Domain Architecture
Description	Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1).

EFG1_HUMAN
NC score	0.424849 (rank : 16)	θ value	9.92553e-07 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RP9, Q96T39	Gene names	GFM1, EFG, EFG1, GFM
Domain Architecture
Description	Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1).

EFG2_MOUSE
NC score	0.423059 (rank : 17)	θ value	1.09739e-05 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R2Q4	Gene names	Gfm2, Efg2
Domain Architecture
Description	Elongation factor G 2, mitochondrial precursor (mEF-G 2) (Elongation factor G2).

EFG2_HUMAN
NC score	0.418780 (rank : 18)	θ value	1.09739e-05 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q969S9, Q8WYI0	Gene names	GFM2, EFG2
Domain Architecture
Description	Elongation factor G 2, mitochondrial precursor (mEF-G 2) (Elongation factor G2).

U5S1_HUMAN
NC score	0.388537 (rank : 19)	θ value	1.99992e-07 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q15029, Q9BUR0	Gene names	EFTUD2, KIAA0031, SNRP116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2) (hSNU114).

U5S1_MOUSE
NC score	0.388406 (rank : 20)	θ value	1.99992e-07 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

EF2_MOUSE
NC score	0.378624 (rank : 21)	θ value	1.09739e-05 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P58252, Q544E4	Gene names	Eef2
Domain Architecture
Description	Elongation factor 2 (EF-2).

EF2_HUMAN
NC score	0.373541 (rank : 22)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P13639	Gene names	EEF2, EF2
Domain Architecture
Description	Elongation factor 2 (EF-2).

IF2P_HUMAN
NC score	0.333365 (rank : 23)	θ value	3.39556e-23 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	889	Shared Neighborhood Hits	35
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF2H_MOUSE
NC score	0.263619 (rank : 24)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0N2	Gene names	Eif2s3y
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 3, Y-linked (Eukaryotic translation initiation factor 2 subunit gamma, Y-linked) (eIF-2-gamma Y).

IF2G_HUMAN
NC score	0.259916 (rank : 25)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P41091	Gene names	EIF2S3, EIF2G
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma).

IF2G_MOUSE
NC score	0.259910 (rank : 26)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0N1	Gene names	Eif2s3x
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 3, X-linked (Eukaryotic translation initiation factor 2 subunit gamma, X-linked) (eIF-2-gamma X).

GTPB1_HUMAN
NC score	0.180846 (rank : 27)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	O00178, Q6IC67	Gene names	GTPBP1
Domain Architecture
Description	GTP-binding protein 1 (G-protein 1) (GP-1) (GP1).

GTPB1_MOUSE
NC score	0.179462 (rank : 28)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	O08582, Q3UD96, Q3UGW6, Q545R1, Q80ZY5	Gene names	Gtpbp1, Gtpbp
Domain Architecture
Description	GTP-binding protein 1 (G-protein 1) (GP-1) (GP1).

GTPB2_HUMAN
NC score	0.159291 (rank : 29)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BX10, Q5T7E8, Q8ND84, Q8TAH7, Q8WUA5, Q9HCS9, Q9NRU4, Q9NX60	Gene names	GTPBP2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2.

GTPB2_MOUSE
NC score	0.158866 (rank : 30)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UJK4, Q9EST7, Q9JIX7	Gene names	Gtpbp2
Domain Architecture	No domain graphic available
Description	GTP-binding protein 2 (GTP-binding-like protein 2).

RASD1_MOUSE
NC score	0.056590 (rank : 31)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	241	Shared Neighborhood Hits	19
SwissProt Accessions	O35626	Gene names	Rasd1, Dexras1
Domain Architecture
Description	Dexamethasone-induced Ras-related protein 1.

ARL11_HUMAN
NC score	0.052875 (rank : 32)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q969Q4	Gene names	ARL11, ARLTS1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1).

RASD1_HUMAN
NC score	0.052732 (rank : 33)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y272, Q9NYB4	Gene names	RASD1, AGS1, DEXRAS1
Domain Architecture
Description	Dexamethasone-induced Ras-related protein 1 (Activator of G-protein signaling 1).

AR13B_HUMAN
NC score	0.051033 (rank : 34)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	528	Shared Neighborhood Hits	12
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

IMDH1_HUMAN
NC score	0.049515 (rank : 35)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P20839, Q8N194, Q96NU2	Gene names	IMPDH1, IMPD1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

RASH_MOUSE
NC score	0.047187 (rank : 36)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	257	Shared Neighborhood Hits	20
SwissProt Accessions	Q61411, Q80WD2	Gene names	Hras1, Hras
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

SRPRB_HUMAN
NC score	0.046407 (rank : 37)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5M8, Q8N2D8	Gene names	SRPRB
Domain Architecture
Description	Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1).

RASE_HUMAN
NC score	0.046142 (rank : 38)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z444	Gene names	ERAS, HRAS2, HRASP
Domain Architecture	No domain graphic available
Description	GTPase ERas precursor (E-Ras) (Embryonic stem cell-expressed Ras).

RHES_MOUSE
NC score	0.045562 (rank : 39)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	P63032, Q9WVD3	Gene names	Rasd2
Domain Architecture	No domain graphic available
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum).

RHES_HUMAN
NC score	0.045110 (rank : 40)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	Q96D21, O95520, Q5THY8	Gene names	RASD2, TEM2
Domain Architecture
Description	GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2).

CCD91_HUMAN
NC score	0.044908 (rank : 41)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	868	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

RASH_HUMAN
NC score	0.044818 (rank : 42)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	263	Shared Neighborhood Hits	20
SwissProt Accessions	P01112, Q14080, Q6FHV9	Gene names	HRAS, HRAS1
Domain Architecture
Description	GTPase HRas precursor (Transforming protein p21) (p21ras) (H-Ras-1) (c-H-ras).

RASK_HUMAN
NC score	0.044155 (rank : 43)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	P01116, P01118, Q96D10	Gene names	KRAS, KRAS2, RASK2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

RASK_MOUSE
NC score	0.044019 (rank : 44)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	P32883, P04200, P08643	Gene names	Kras, Kras2
Domain Architecture
Description	GTPase KRas (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras).

IMDH1_MOUSE
NC score	0.043187 (rank : 45)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P50096	Gene names	Impdh1
Domain Architecture
Description	Inosine-5'-monophosphate dehydrogenase 1 (EC 1.1.1.205) (IMP dehydrogenase 1) (IMPDH-I) (IMPD 1).

RASN_MOUSE
NC score	0.041646 (rank : 46)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P08556	Gene names	Nras
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

RASN_HUMAN
NC score	0.041633 (rank : 47)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	P01111, Q14971, Q15104, Q15282	Gene names	NRAS
Domain Architecture
Description	GTPase NRas precursor (Transforming protein N-Ras).

SRPRB_MOUSE
NC score	0.039257 (rank : 48)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P47758, Q544X9, Q9D872	Gene names	Srprb
Domain Architecture
Description	Signal recognition particle receptor subunit beta (SR-beta).

AR13B_MOUSE
NC score	0.039050 (rank : 49)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	245	Shared Neighborhood Hits	14
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

ARL3_HUMAN
NC score	0.037434 (rank : 50)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	257	Shared Neighborhood Hits	12
SwissProt Accessions	P36405	Gene names	ARL3, ARFL3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

ARL3_MOUSE
NC score	0.036923 (rank : 51)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	258	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WUL7	Gene names	Arl3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

RASM_MOUSE
NC score	0.036290 (rank : 52)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	251	Shared Neighborhood Hits	22
SwissProt Accessions	O08989	Gene names	Mras, Xras
Domain Architecture
Description	Ras-related protein M-Ras (Ras-related protein R-Ras3) (Muscle and microspikes Ras) (X-Ras).

RASM_HUMAN
NC score	0.036088 (rank : 53)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	250	Shared Neighborhood Hits	21
SwissProt Accessions	O14807, Q86WX8	Gene names	MRAS, RRAS3
Domain Architecture
Description	Ras-related protein M-Ras (Ras-related protein R-Ras3).

RAP1A_HUMAN
NC score	0.034814 (rank : 54)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	P62834, P10113	Gene names	RAP1A, KREV1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rap-1A precursor (GTP-binding protein smg-p21A) (Ras-related protein Krev-1) (C21KG) (G-22K).

RAP1A_MOUSE
NC score	0.034814 (rank : 55)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	260	Shared Neighborhood Hits	19
SwissProt Accessions	P62835, P10113	Gene names	Rap1a, Krev-1
Domain Architecture	No domain graphic available
Description	Ras-related protein Rap-1A precursor (Ras-related protein Krev-1).

HIP1_HUMAN
NC score	0.034519 (rank : 56)	θ value	0.00869519 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	1016	Shared Neighborhood Hits	14
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

STMN2_HUMAN
NC score	0.034026 (rank : 57)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.034026 (rank : 58)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	458	Shared Neighborhood Hits	13
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

ERAL_MOUSE
NC score	0.032594 (rank : 59)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

VPS16_HUMAN
NC score	0.031535 (rank : 60)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H269, Q5JUB1, Q8WU31, Q96EE7, Q96N92, Q9H1Q4, Q9H1Q5	Gene names	VPS16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (hVPS16).

GLU2B_HUMAN
NC score	0.025177 (rank : 61)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	377	Shared Neighborhood Hits	10
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

VPS16_MOUSE
NC score	0.024816 (rank : 62)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q920Q4, Q8R3C3, Q99KZ4	Gene names	Vps16
Domain Architecture
Description	Vacuolar protein sorting-associated protein 16 (mVPS16).

SH24A_HUMAN
NC score	0.023997 (rank : 63)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

RAB36_HUMAN
NC score	0.023586 (rank : 64)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	264	Shared Neighborhood Hits	21
SwissProt Accessions	O95755, Q7Z4A9, Q9UHP5	Gene names	RAB36
Domain Architecture
Description	Ras-related protein Rab-36.

AL3A1_HUMAN
NC score	0.022376 (rank : 65)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

TLN1_HUMAN
NC score	0.021572 (rank : 66)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.021477 (rank : 67)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

AL3A2_MOUSE
NC score	0.021269 (rank : 68)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	P47740	Gene names	Aldh3a2, Ahd-3, Ahd3, Aldh3, Aldh4
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

BCLF1_HUMAN
NC score	0.020409 (rank : 69)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

SVIL_MOUSE
NC score	0.020271 (rank : 70)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	439	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

AL3A2_HUMAN
NC score	0.017946 (rank : 71)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P51648, Q93011, Q96J37	Gene names	ALDH3A2, ALDH10, FALDH
Domain Architecture
Description	Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10).

NUMA1_HUMAN
NC score	0.014212 (rank : 72)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	1523	Shared Neighborhood Hits	20
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PCNT_HUMAN
NC score	0.013231 (rank : 73)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	1551	Shared Neighborhood Hits	14
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

DGKK_HUMAN
NC score	0.013057 (rank : 74)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	378	Shared Neighborhood Hits	4
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

MPP5_MOUSE
NC score	0.011156 (rank : 75)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

GBP1_HUMAN
NC score	0.010010 (rank : 76)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	339	Shared Neighborhood Hits	10
SwissProt Accessions	P32455	Gene names	GBP1
Domain Architecture
Description	Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (GBP-1) (HuGBP-1).

BPA1_MOUSE
NC score	0.008795 (rank : 77)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	1477	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

KIF5C_MOUSE
NC score	0.005883 (rank : 78)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KRHB1_HUMAN
NC score	0.004857 (rank : 79)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	461	Shared Neighborhood Hits	8
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB6_HUMAN
NC score	0.004490 (rank : 80)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

CHD1_HUMAN
NC score	0.003444 (rank : 81)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	337	Shared Neighborhood Hits	4
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NEK11_HUMAN
NC score	0.000755 (rank : 82)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	1043	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).