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Network neighborhood for query Sequence : SGOL2_MOUSE

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SGOL2_MOUSE
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SGOL2_HUMAN
θ value	0 (rank : 1)	NC score	0.813783 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SGOL2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

CYLC1_HUMAN
θ value	0.000270298 (rank : 3)	NC score	0.131442 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	408	Shared Neighborhood Hits	34
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

RAI14_MOUSE
θ value	0.00390308 (rank : 4)	NC score	0.048191 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	1505	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CCD46_MOUSE
θ value	0.00869519 (rank : 5)	NC score	0.058313 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	1405	Shared Neighborhood Hits	56
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TTC16_HUMAN
θ value	0.0148317 (rank : 6)	NC score	0.075591 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

RECQ5_HUMAN
θ value	0.21417 (rank : 7)	NC score	0.037850 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	390	Shared Neighborhood Hits	6
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

CEBPB_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.067648 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	141	Shared Neighborhood Hits	13
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

AKAP9_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.056230 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	1710	Shared Neighborhood Hits	55
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BCOR_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.033690 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	609	Shared Neighborhood Hits	8
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

DNM3A_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.036883 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

CIR_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.065936 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	255	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

HTSF1_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.051303 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

PPRB_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.041935 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RSF1_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.065920 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	539	Shared Neighborhood Hits	40
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

ZN638_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.046781 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	343	Shared Neighborhood Hits	17
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ANR26_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.039895 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	1554	Shared Neighborhood Hits	47
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

KI21A_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.035536 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	1317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LEO1_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.038778 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	958	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NOL8_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.048694 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

ROCK2_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.023872 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	2073	Shared Neighborhood Hits	50
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

BUB1_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.029129 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	543	Shared Neighborhood Hits	8
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

MY18A_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.040997 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	1989	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

AHTF1_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.040534 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

GLI3_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.010206 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	871	Shared Neighborhood Hits	9
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

KI21A_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.034442 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	1543	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MINT_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.038875 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	1291	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MY18A_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.043735 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	1929	Shared Neighborhood Hits	57
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SUHW3_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.012831 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	697	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

TAF3_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.038257 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	568	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

DSCAM_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.008436 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	524	Shared Neighborhood Hits	3
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

GLI3_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.009597 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	807	Shared Neighborhood Hits	8
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

LAMC1_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.027033 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	922	Shared Neighborhood Hits	34
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PKP1_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.027437 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

RB6I2_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.042807 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	1584	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.051289 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	1433	Shared Neighborhood Hits	51
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TMCC3_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.034994 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TSC1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.048925 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	765	Shared Neighborhood Hits	31
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

ZFP37_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.002564 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	797	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6Q3	Gene names	ZFP37
Domain Architecture
Description	Zinc finger protein 37 homolog (Zfp-37).

CD68_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.032394 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P31996	Gene names	Cd68
Domain Architecture
Description	Macrosialin precursor (CD68 antigen).

ELOA3_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.026965 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

LIN1_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.053507 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

LIPA2_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.051786 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	1282	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYO5A_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.031643 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	1092	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NAB1_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.024652 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q13506, O75383, O75384, Q6GTU1, Q9UEV1	Gene names	NAB1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54).

PCDH7_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.005357 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PCNT_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.044121 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	1551	Shared Neighborhood Hits	53
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PKP1_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.026955 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PPIG_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.032711 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

ROCK2_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.028479 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	2072	Shared Neighborhood Hits	55
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TBC13_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.031101 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVG8	Gene names	TBC1D13
Domain Architecture
Description	TBC1 domain family member 13.

ZFP37_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.003390 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

CENPF_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.040174 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	1932	Shared Neighborhood Hits	57
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

EDEM3_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.018590 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

EEA1_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.051061 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	1796	Shared Neighborhood Hits	60
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

LAMC1_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.025081 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	856	Shared Neighborhood Hits	38
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LIPA2_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.043395 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	1044	Shared Neighborhood Hits	45
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LRRF2_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.045281 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	791	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

POF1B_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.043024 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	530	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

SPEG_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.004416 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	1959	Shared Neighborhood Hits	15
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYCP3_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.029375 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	155	Shared Neighborhood Hits	11
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

TOX_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.019359 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

CENPE_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.050642 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	2060	Shared Neighborhood Hits	59
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CMGA_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.033271 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

CYTSA_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.041917 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	1138	Shared Neighborhood Hits	47
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.041905 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	1104	Shared Neighborhood Hits	46
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

JADE3_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.012776 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

K1C17_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.015860 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	456	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

OXR1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.034964 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	282	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

RP1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.021665 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

5NT1B_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.017410 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

APC_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.031066 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	603	Shared Neighborhood Hits	29
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.033501 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	441	Shared Neighborhood Hits	32
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ATAD2_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.014227 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	322	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BNC2_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.014581 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	456	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

C8AP2_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.029513 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	405	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CEBPA_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.039979 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CEBPA_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.039801 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

NIN_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.040314 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	1416	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NMT1_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.020465 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P30419, Q9UE09	Gene names	NMT1, NMT
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Peptide N- myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase).

NMT1_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.020483 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	O70310	Gene names	Nmt1
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Peptide N- myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase).

NUF2_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.040408 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	661	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

POK10_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.027592 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	P10266, P87890, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pol protein (HERV-K10 Pol protein) (HERV-K107 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK12_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.023556 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK17_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.033781 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK20_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.029084 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQG0, Q6KH06, Q86YP3	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_3q27.3 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK2_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.033802 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXR3, Q6KH04, Q9BXR4, Q9UKH5, Q9UP31, Q9WIK9, Q9WJR4	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein) (HERV-K108 Pol protein) (HERV-K(C7) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK3_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.033816 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.033804 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK7_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.033818 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

SHC3_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.009692 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SYNE2_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.042569 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	1323	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TMCC3_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.038290 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	202	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

AFF4_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.024425 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	611	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ASPM_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.016609 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

CAF1A_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.037405 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	750	Shared Neighborhood Hits	39
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD13_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.042358 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	721	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

DPOLZ_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.017964 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

EP15_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.033122 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	1021	Shared Neighborhood Hits	40
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ESCO1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.030725 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	361	Shared Neighborhood Hits	29
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

FA61B_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.013572 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX40, Q6PFW8, Q96LH8	Gene names	FAM61B, C20orf40
Domain Architecture	No domain graphic available
Description	Protein FAM61B.

GBF1_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.009858 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

MDC1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.015142 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	998	Shared Neighborhood Hits	28
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MYO5A_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.029926 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	1117	Shared Neighborhood Hits	48
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

OXR1_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.032081 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	516	Shared Neighborhood Hits	24
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

RIMB1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.027749 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	1479	Shared Neighborhood Hits	42
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RUFY1_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.034930 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	848	Shared Neighborhood Hits	38
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SACS_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.012713 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

SETD4_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.016492 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVD3, Q9BU46	Gene names	SETD4, C21orf18
Domain Architecture	No domain graphic available
Description	SET domain-containing protein 4.

SGOL1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.019542 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

YO11_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.032775 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

ZWINT_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.032075 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	497	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CCD46_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.058331 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	1430	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CE152_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.050327 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	976	Shared Neighborhood Hits	42
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

GOGA4_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.050081 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	2034	Shared Neighborhood Hits	57
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RBCC1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.050295 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	1023	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SYCP1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.051073 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	1456	Shared Neighborhood Hits	56
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.070542 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	230	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TRIPB_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.054239 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	1587	Shared Neighborhood Hits	53
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

Hits sorted by NC score

SGOL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

SGOL2_HUMAN
NC score	0.813783 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

CYLC1_HUMAN
NC score	0.131442 (rank : 3)	θ value	0.000270298 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	408	Shared Neighborhood Hits	34
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TTC16_HUMAN
NC score	0.075591 (rank : 4)	θ value	0.0148317 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

SYCP2_HUMAN
NC score	0.070542 (rank : 5)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	230	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

CEBPB_HUMAN
NC score	0.067648 (rank : 6)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	141	Shared Neighborhood Hits	13
SwissProt Accessions	P17676, Q96IH2, Q9H4Z5	Gene names	CEBPB, TCF5
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).

CIR_MOUSE
NC score	0.065936 (rank : 7)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	255	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

RSF1_HUMAN
NC score	0.065920 (rank : 8)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	539	Shared Neighborhood Hits	40
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CCD46_HUMAN
NC score	0.058331 (rank : 9)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	1430	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
NC score	0.058313 (rank : 10)	θ value	0.00869519 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	1405	Shared Neighborhood Hits	56
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

AKAP9_HUMAN
NC score	0.056230 (rank : 11)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	1710	Shared Neighborhood Hits	55
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

TRIPB_HUMAN
NC score	0.054239 (rank : 12)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	1587	Shared Neighborhood Hits	53
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

LIN1_HUMAN
NC score	0.053507 (rank : 13)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	187	Shared Neighborhood Hits	14
SwissProt Accessions	P08547	Gene names
Domain Architecture	No domain graphic available
Description	LINE-1 reverse transcriptase homolog.

LIPA2_MOUSE
NC score	0.051786 (rank : 14)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	1282	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

HTSF1_HUMAN
NC score	0.051303 (rank : 15)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

RB6I2_MOUSE
NC score	0.051289 (rank : 16)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	1433	Shared Neighborhood Hits	51
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

SYCP1_MOUSE
NC score	0.051073 (rank : 17)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	1456	Shared Neighborhood Hits	56
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EEA1_HUMAN
NC score	0.051061 (rank : 18)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	1796	Shared Neighborhood Hits	60
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CENPE_HUMAN
NC score	0.050642 (rank : 19)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	2060	Shared Neighborhood Hits	59
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CE152_HUMAN
NC score	0.050327 (rank : 20)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	976	Shared Neighborhood Hits	42
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

RBCC1_HUMAN
NC score	0.050295 (rank : 21)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	1023	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

GOGA4_HUMAN
NC score	0.050081 (rank : 22)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	2034	Shared Neighborhood Hits	57
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

TSC1_HUMAN
NC score	0.048925 (rank : 23)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	765	Shared Neighborhood Hits	31
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

NOL8_HUMAN
NC score	0.048694 (rank : 24)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	297	Shared Neighborhood Hits	19
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

RAI14_MOUSE
NC score	0.048191 (rank : 25)	θ value	0.00390308 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	1505	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ZN638_HUMAN
NC score	0.046781 (rank : 26)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	343	Shared Neighborhood Hits	17
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

LRRF2_HUMAN
NC score	0.045281 (rank : 27)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	791	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

PCNT_HUMAN
NC score	0.044121 (rank : 28)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	1551	Shared Neighborhood Hits	53
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

MY18A_HUMAN
NC score	0.043735 (rank : 29)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	1929	Shared Neighborhood Hits	57
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

LIPA2_HUMAN
NC score	0.043395 (rank : 30)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	1044	Shared Neighborhood Hits	45
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

POF1B_MOUSE
NC score	0.043024 (rank : 31)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	530	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

RB6I2_HUMAN
NC score	0.042807 (rank : 32)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	1584	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SYNE2_HUMAN
NC score	0.042569 (rank : 33)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1323	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CCD13_HUMAN
NC score	0.042358 (rank : 34)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	721	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

PPRB_MOUSE
NC score	0.041935 (rank : 35)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	354	Shared Neighborhood Hits	9
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

CYTSA_HUMAN
NC score	0.041917 (rank : 36)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	1138	Shared Neighborhood Hits	47
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
NC score	0.041905 (rank : 37)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	1104	Shared Neighborhood Hits	46
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

MY18A_MOUSE
NC score	0.040997 (rank : 38)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	1989	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

AHTF1_HUMAN
NC score	0.040534 (rank : 39)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	286	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

NUF2_HUMAN
NC score	0.040408 (rank : 40)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	661	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

NIN_HUMAN
NC score	0.040314 (rank : 41)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	1416	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CENPF_HUMAN
NC score	0.040174 (rank : 42)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	1932	Shared Neighborhood Hits	57
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEBPA_HUMAN
NC score	0.039979 (rank : 43)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P49715, P78319	Gene names	CEBPA
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

ANR26_MOUSE
NC score	0.039895 (rank : 44)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	1554	Shared Neighborhood Hits	47
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CEBPA_MOUSE
NC score	0.039801 (rank : 45)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

MINT_HUMAN
NC score	0.038875 (rank : 46)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	1291	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

LEO1_HUMAN
NC score	0.038778 (rank : 47)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	958	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TMCC3_HUMAN
NC score	0.038290 (rank : 48)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	202	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

TAF3_HUMAN
NC score	0.038257 (rank : 49)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	568	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RECQ5_HUMAN
NC score	0.037850 (rank : 50)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	390	Shared Neighborhood Hits	6
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

CAF1A_HUMAN
NC score	0.037405 (rank : 51)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	750	Shared Neighborhood Hits	39
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DNM3A_MOUSE
NC score	0.036883 (rank : 52)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

KI21A_MOUSE
NC score	0.035536 (rank : 53)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	1317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TMCC3_MOUSE
NC score	0.034994 (rank : 54)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R310	Gene names	Tmcc3
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

OXR1_HUMAN
NC score	0.034964 (rank : 55)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	282	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

RUFY1_HUMAN
NC score	0.034930 (rank : 56)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	848	Shared Neighborhood Hits	38
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

KI21A_HUMAN
NC score	0.034442 (rank : 57)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	1543	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

POK7_HUMAN
NC score	0.033818 (rank : 58)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

POK3_HUMAN
NC score	0.033816 (rank : 59)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
NC score	0.033804 (rank : 60)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK2_HUMAN
NC score	0.033802 (rank : 61)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXR3, Q6KH04, Q9BXR4, Q9UKH5, Q9UP31, Q9WIK9, Q9WJR4	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein) (HERV-K108 Pol protein) (HERV-K(C7) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK17_HUMAN
NC score	0.033781 (rank : 62)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

BCOR_HUMAN
NC score	0.033690 (rank : 63)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	609	Shared Neighborhood Hits	8
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

APC_MOUSE
NC score	0.033501 (rank : 64)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	441	Shared Neighborhood Hits	32
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CMGA_MOUSE
NC score	0.033271 (rank : 65)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

EP15_HUMAN
NC score	0.033122 (rank : 66)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	1021	Shared Neighborhood Hits	40
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

YO11_MOUSE
NC score	0.032775 (rank : 67)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	P11260	Gene names
Domain Architecture
Description	Hypothetical protein ORF-1137.

PPIG_HUMAN
NC score	0.032711 (rank : 68)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CD68_MOUSE
NC score	0.032394 (rank : 69)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P31996	Gene names	Cd68
Domain Architecture
Description	Macrosialin precursor (CD68 antigen).

OXR1_MOUSE
NC score	0.032081 (rank : 70)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	516	Shared Neighborhood Hits	24
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

ZWINT_MOUSE
NC score	0.032075 (rank : 71)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	497	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

MYO5A_HUMAN
NC score	0.031643 (rank : 72)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	1092	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

TBC13_HUMAN
NC score	0.031101 (rank : 73)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVG8	Gene names	TBC1D13
Domain Architecture
Description	TBC1 domain family member 13.

APC_HUMAN
NC score	0.031066 (rank : 74)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	603	Shared Neighborhood Hits	29
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ESCO1_HUMAN
NC score	0.030725 (rank : 75)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	361	Shared Neighborhood Hits	29
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

MYO5A_MOUSE
NC score	0.029926 (rank : 76)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	1117	Shared Neighborhood Hits	48
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

C8AP2_MOUSE
NC score	0.029513 (rank : 77)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	405	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

SYCP3_MOUSE
NC score	0.029375 (rank : 78)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	155	Shared Neighborhood Hits	11
SwissProt Accessions	P70281, Q3V2A4, Q549A7	Gene names	Sycp3, Scp3
Domain Architecture
Description	Synaptonemal complex protein 3 (SCP-3).

BUB1_HUMAN
NC score	0.029129 (rank : 79)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	543	Shared Neighborhood Hits	8
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

POK20_HUMAN
NC score	0.029084 (rank : 80)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQG0, Q6KH06, Q86YP3	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_3q27.3 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

ROCK2_MOUSE
NC score	0.028479 (rank : 81)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	2072	Shared Neighborhood Hits	55
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RIMB1_HUMAN
NC score	0.027749 (rank : 82)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	1479	Shared Neighborhood Hits	42
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

POK10_HUMAN
NC score	0.027592 (rank : 83)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	P10266, P87890, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pol protein (HERV-K10 Pol protein) (HERV-K107 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

PKP1_MOUSE
NC score	0.027437 (rank : 84)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

LAMC1_HUMAN
NC score	0.027033 (rank : 85)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	922	Shared Neighborhood Hits	34
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ELOA3_HUMAN
NC score	0.026965 (rank : 86)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

PKP1_HUMAN
NC score	0.026955 (rank : 87)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

LAMC1_MOUSE
NC score	0.025081 (rank : 88)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	856	Shared Neighborhood Hits	38
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NAB1_HUMAN
NC score	0.024652 (rank : 89)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q13506, O75383, O75384, Q6GTU1, Q9UEV1	Gene names	NAB1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54).

AFF4_HUMAN
NC score	0.024425 (rank : 90)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	611	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ROCK2_HUMAN
NC score	0.023872 (rank : 91)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	2073	Shared Neighborhood Hits	50
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

POK12_HUMAN
NC score	0.023556 (rank : 92)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

RP1_MOUSE
NC score	0.021665 (rank : 93)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	P56716	Gene names	Rp1, Orp1, Rp1h
Domain Architecture
Description	Oxygen-regulated protein 1 (Retinitis pigmentosa RP1 protein homolog).

NMT1_MOUSE
NC score	0.020483 (rank : 94)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	O70310	Gene names	Nmt1
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Peptide N- myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase).

NMT1_HUMAN
NC score	0.020465 (rank : 95)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P30419, Q9UE09	Gene names	NMT1, NMT
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Peptide N- myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase).

SGOL1_HUMAN
NC score	0.019542 (rank : 96)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

TOX_HUMAN
NC score	0.019359 (rank : 97)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

EDEM3_HUMAN
NC score	0.018590 (rank : 98)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

DPOLZ_HUMAN
NC score	0.017964 (rank : 99)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

5NT1B_MOUSE
NC score	0.017410 (rank : 100)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YE9, Q91Y48	Gene names	Nt5c1b, Airp
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

ASPM_HUMAN
NC score	0.016609 (rank : 101)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

SETD4_HUMAN
NC score	0.016492 (rank : 102)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVD3, Q9BU46	Gene names	SETD4, C21orf18
Domain Architecture	No domain graphic available
Description	SET domain-containing protein 4.

K1C17_MOUSE
NC score	0.015860 (rank : 103)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	456	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QWL7, Q61783	Gene names	Krt17, Krt1-17
Domain Architecture
Description	Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17).

MDC1_MOUSE
NC score	0.015142 (rank : 104)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	998	Shared Neighborhood Hits	28
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BNC2_MOUSE
NC score	0.014581 (rank : 105)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	456	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BMQ3, Q6T3A4	Gene names	Bnc2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

ATAD2_HUMAN
NC score	0.014227 (rank : 106)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	322	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

FA61B_HUMAN
NC score	0.013572 (rank : 107)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX40, Q6PFW8, Q96LH8	Gene names	FAM61B, C20orf40
Domain Architecture	No domain graphic available
Description	Protein FAM61B.

SUHW3_MOUSE
NC score	0.012831 (rank : 108)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	697	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

JADE3_HUMAN
NC score	0.012776 (rank : 109)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

SACS_HUMAN
NC score	0.012713 (rank : 110)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

GLI3_HUMAN
NC score	0.010206 (rank : 111)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	871	Shared Neighborhood Hits	9
SwissProt Accessions	P10071, O75219, Q9UDT5, Q9UJ39	Gene names	GLI3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

GBF1_HUMAN
NC score	0.009858 (rank : 112)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

SHC3_HUMAN
NC score	0.009692 (rank : 113)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

GLI3_MOUSE
NC score	0.009597 (rank : 114)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	807	Shared Neighborhood Hits	8
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

DSCAM_HUMAN
NC score	0.008436 (rank : 115)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	524	Shared Neighborhood Hits	3
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

PCDH7_HUMAN
NC score	0.005357 (rank : 116)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

SPEG_MOUSE
NC score	0.004416 (rank : 117)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	1959	Shared Neighborhood Hits	15
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZFP37_MOUSE
NC score	0.003390 (rank : 118)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZFP37_HUMAN
NC score	0.002564 (rank : 119)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	797	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6Q3	Gene names	ZFP37
Domain Architecture
Description	Zinc finger protein 37 homolog (Zfp-37).