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Network neighborhood for query Sequence : POK3_HUMAN

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POK3_HUMAN
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

POK10_HUMAN
θ value	0 (rank : 1)	NC score	0.822643 (rank : 11)
Query Neighborhood Hits	27	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	P10266, P87890, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pol protein (HERV-K10 Pol protein) (HERV-K107 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK12_HUMAN
θ value	0 (rank : 2)	NC score	0.704358 (rank : 12)
Query Neighborhood Hits	27	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK17_HUMAN
θ value	0 (rank : 3)	NC score	0.999666 (rank : 3)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK20_HUMAN
θ value	0 (rank : 4)	NC score	0.866547 (rank : 10)
Query Neighborhood Hits	27	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQG0, Q6KH06, Q86YP3	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_3q27.3 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK2_HUMAN
θ value	0 (rank : 5)	NC score	0.999686 (rank : 2)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXR3, Q6KH04, Q9BXR4, Q9UKH5, Q9UP31, Q9WIK9, Q9WJR4	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein) (HERV-K108 Pol protein) (HERV-K(C7) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK3_HUMAN
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK5_HUMAN
θ value	0 (rank : 7)	NC score	0.999608 (rank : 4)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P63132	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
θ value	0 (rank : 8)	NC score	0.999565 (rank : 5)
Query Neighborhood Hits	27	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK7_HUMAN
θ value	0 (rank : 9)	NC score	0.999301 (rank : 6)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

POK9_HUMAN
θ value	0 (rank : 10)	NC score	0.993027 (rank : 7)
Query Neighborhood Hits	27	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P63134	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Pol protein (HERV-K104 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

POK11_HUMAN
θ value	1.47209e-143 (rank : 11)	NC score	0.987719 (rank : 8)
Query Neighborhood Hits	27	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	P87893	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Pol protein (HERV-K101 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

POK4_HUMAN
θ value	2.2976e-104 (rank : 12)	NC score	0.984761 (rank : 9)
Query Neighborhood Hits	27	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P63128, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Pol protein (HERV-K109 Pol protein) (HERV-K(C6) Pol protein).

IGEB_MOUSE
θ value	7.0802e-21 (rank : 13)	NC score	0.603166 (rank : 13)
Query Neighborhood Hits	27	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

CD22_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.030391 (rank : 36)
Query Neighborhood Hits	27	Target Neighborhood Hits	365	Shared Neighborhood Hits	10
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

ARS2_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.017566 (rank : 41)
Query Neighborhood Hits	27	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

CHK2_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.000371 (rank : 46)
Query Neighborhood Hits	27	Target Neighborhood Hits	859	Shared Neighborhood Hits	6
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

SETX_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.021439 (rank : 40)
Query Neighborhood Hits	27	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

DYHC_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.025458 (rank : 38)
Query Neighborhood Hits	27	Target Neighborhood Hits	733	Shared Neighborhood Hits	12
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.025480 (rank : 37)
Query Neighborhood Hits	27	Target Neighborhood Hits	729	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

GCKR_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.053093 (rank : 33)
Query Neighborhood Hits	27	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q14397, Q53RY6, Q99522	Gene names	GCKR
Domain Architecture
Description	Glucokinase regulatory protein (Glucokinase regulator).

ZN452_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.024960 (rank : 39)
Query Neighborhood Hits	27	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q6R2W3, Q2NKL9, Q5SRJ3, Q8TCN2, Q96PW3	Gene names	ZNF452, KIAA1925
Domain Architecture	No domain graphic available
Description	Protein ZNF452.

E41L3_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.016232 (rank : 42)
Query Neighborhood Hits	27	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

RASA1_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.003383 (rank : 45)
Query Neighborhood Hits	27	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CU006_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.032874 (rank : 35)
Query Neighborhood Hits	27	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P57060	Gene names	C21orf6
Domain Architecture
Description	Protein C21orf6.

SETB1_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.004817 (rank : 43)
Query Neighborhood Hits	27	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SGOL2_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.033816 (rank : 34)
Query Neighborhood Hits	27	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

HDGR3_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.004746 (rank : 44)
Query Neighborhood Hits	27	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

ENK10_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.167427 (rank : 16)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P10267, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K10 envelope protein) (HERV-K107 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK11_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.166534 (rank : 18)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P61566	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K101 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK12_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.167162 (rank : 17)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P61567	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K102 envelope protein) (HERV-K(III) envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK13_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.162583 (rank : 20)
Query Neighborhood Hits	27	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P61568	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK14_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.080336 (rank : 31)
Query Neighborhood Hits	27	Target Neighborhood Hits	19	Shared Neighborhood Hits	1
SwissProt Accessions	Q9NX77	Gene names
Domain Architecture
Description	HERV-K_16p3.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK15_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.201184 (rank : 14)
Query Neighborhood Hits	27	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HDC0	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(I) envelope protein) [Includes: Truncated surface protein (SU)].

ENK16_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.161126 (rank : 21)
Query Neighborhood Hits	27	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P61569	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_10p14 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK17_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.152090 (rank : 23)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P61570	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK19_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.151546 (rank : 28)
Query Neighborhood Hits	27	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVY0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK1_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.151523 (rank : 29)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P61565	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (EnvK1 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK2_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.151900 (rank : 24)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q69384, Q8TD93, Q9UBU4, Q9YNA5, Q9YNA9	Gene names	ERVK6
Domain Architecture
Description	HERV-K_7p22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(HML-2.HOM) envelope protein) (HERV-K108 envelope protein) (HERV-K(C7) envelope protein) (EnvK2 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK3_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.151871 (rank : 26)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O71037, Q69386, Q9YNA7	Gene names
Domain Architecture
Description	HERV-K_19q12 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(C19) envelope protein) (EnvK3 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK4_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.151423 (rank : 30)
Query Neighborhood Hits	27	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKH3	Gene names
Domain Architecture
Description	HERV-K_6q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K109 envelope protein) (HERV-K(C6) envelope protein) (EnvK4 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK5_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.151885 (rank : 25)
Query Neighborhood Hits	27	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q902F9	Gene names
Domain Architecture
Description	HERV-K_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K113 envelope protein) (EnvK5 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK6_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.151838 (rank : 27)
Query Neighborhood Hits	27	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q902F8	Gene names
Domain Architecture
Description	HERV-K_8p23.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K115 envelope protein) (EnvK6 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK7_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.166418 (rank : 19)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	O42043, O95280, Q96PI3, Q96PI6, Q9QC06	Gene names
Domain Architecture
Description	HERV-K_1q23.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K18 envelope protein) (HERV-K110 envelope protein) (IDDMK1,2 22 envelope protein) (HERV-K(C1a) envelope protein) (HERV- K18 superantigen) (IDDMK1,2 22 superantigen) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK8_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.182797 (rank : 15)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HDB8	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(II) envelope protein) [Includes: Truncated surface protein (SU)].

ENK9_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.157333 (rank : 22)
Query Neighborhood Hits	27	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKH7	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K104 envelope protein) [Includes: Truncated surface protein (SU)].

UB7I3_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.070086 (rank : 32)
Query Neighborhood Hits	27	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

Hits sorted by NC score

POK3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK2_HUMAN
NC score	0.999686 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXR3, Q6KH04, Q9BXR4, Q9UKH5, Q9UP31, Q9WIK9, Q9WJR4	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein) (HERV-K108 Pol protein) (HERV-K(C7) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK17_HUMAN
NC score	0.999666 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	22
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK5_HUMAN
NC score	0.999608 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P63132	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
NC score	0.999565 (rank : 5)	θ value	0 (rank : 8)
Query Neighborhood Hits	27	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK7_HUMAN
NC score	0.999301 (rank : 6)	θ value	0 (rank : 9)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

POK9_HUMAN
NC score	0.993027 (rank : 7)	θ value	0 (rank : 10)
Query Neighborhood Hits	27	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	P63134	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Pol protein (HERV-K104 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

POK11_HUMAN
NC score	0.987719 (rank : 8)	θ value	1.47209e-143 (rank : 11)
Query Neighborhood Hits	27	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	P87893	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Pol protein (HERV-K101 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

POK4_HUMAN
NC score	0.984761 (rank : 9)	θ value	2.2976e-104 (rank : 12)
Query Neighborhood Hits	27	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P63128, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Pol protein (HERV-K109 Pol protein) (HERV-K(C6) Pol protein).

POK20_HUMAN
NC score	0.866547 (rank : 10)	θ value	0 (rank : 4)
Query Neighborhood Hits	27	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQG0, Q6KH06, Q86YP3	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_3q27.3 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK10_HUMAN
NC score	0.822643 (rank : 11)	θ value	0 (rank : 1)
Query Neighborhood Hits	27	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	P10266, P87890, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pol protein (HERV-K10 Pol protein) (HERV-K107 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK12_HUMAN
NC score	0.704358 (rank : 12)	θ value	0 (rank : 2)
Query Neighborhood Hits	27	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

IGEB_MOUSE
NC score	0.603166 (rank : 13)	θ value	7.0802e-21 (rank : 13)
Query Neighborhood Hits	27	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

ENK15_HUMAN
NC score	0.201184 (rank : 14)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	27	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HDC0	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(I) envelope protein) [Includes: Truncated surface protein (SU)].

ENK8_HUMAN
NC score	0.182797 (rank : 15)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HDB8	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(II) envelope protein) [Includes: Truncated surface protein (SU)].

ENK10_HUMAN
NC score	0.167427 (rank : 16)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P10267, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K10 envelope protein) (HERV-K107 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK12_HUMAN
NC score	0.167162 (rank : 17)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P61567	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K102 envelope protein) (HERV-K(III) envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK11_HUMAN
NC score	0.166534 (rank : 18)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P61566	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K101 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK7_HUMAN
NC score	0.166418 (rank : 19)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	O42043, O95280, Q96PI3, Q96PI6, Q9QC06	Gene names
Domain Architecture
Description	HERV-K_1q23.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K18 envelope protein) (HERV-K110 envelope protein) (IDDMK1,2 22 envelope protein) (HERV-K(C1a) envelope protein) (HERV- K18 superantigen) (IDDMK1,2 22 superantigen) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK13_HUMAN
NC score	0.162583 (rank : 20)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	27	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P61568	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK16_HUMAN
NC score	0.161126 (rank : 21)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	27	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P61569	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_10p14 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK9_HUMAN
NC score	0.157333 (rank : 22)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	27	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKH7	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K104 envelope protein) [Includes: Truncated surface protein (SU)].

ENK17_HUMAN
NC score	0.152090 (rank : 23)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P61570	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK2_HUMAN
NC score	0.151900 (rank : 24)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q69384, Q8TD93, Q9UBU4, Q9YNA5, Q9YNA9	Gene names	ERVK6
Domain Architecture
Description	HERV-K_7p22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(HML-2.HOM) envelope protein) (HERV-K108 envelope protein) (HERV-K(C7) envelope protein) (EnvK2 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK5_HUMAN
NC score	0.151885 (rank : 25)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	27	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q902F9	Gene names
Domain Architecture
Description	HERV-K_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K113 envelope protein) (EnvK5 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK3_HUMAN
NC score	0.151871 (rank : 26)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O71037, Q69386, Q9YNA7	Gene names
Domain Architecture
Description	HERV-K_19q12 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(C19) envelope protein) (EnvK3 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK6_HUMAN
NC score	0.151838 (rank : 27)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	27	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q902F8	Gene names
Domain Architecture
Description	HERV-K_8p23.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K115 envelope protein) (EnvK6 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK19_HUMAN
NC score	0.151546 (rank : 28)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	27	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZVY0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK1_HUMAN
NC score	0.151523 (rank : 29)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	27	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P61565	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (EnvK1 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK4_HUMAN
NC score	0.151423 (rank : 30)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	27	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKH3	Gene names
Domain Architecture
Description	HERV-K_6q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K109 envelope protein) (HERV-K(C6) envelope protein) (EnvK4 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK14_HUMAN
NC score	0.080336 (rank : 31)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	27	Target Neighborhood Hits	19	Shared Neighborhood Hits	1
SwissProt Accessions	Q9NX77	Gene names
Domain Architecture
Description	HERV-K_16p3.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

UB7I3_HUMAN
NC score	0.070086 (rank : 32)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	27	Target Neighborhood Hits	136	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

GCKR_HUMAN
NC score	0.053093 (rank : 33)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	27	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q14397, Q53RY6, Q99522	Gene names	GCKR
Domain Architecture
Description	Glucokinase regulatory protein (Glucokinase regulator).

SGOL2_MOUSE
NC score	0.033816 (rank : 34)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	27	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

CU006_HUMAN
NC score	0.032874 (rank : 35)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	27	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P57060	Gene names	C21orf6
Domain Architecture
Description	Protein C21orf6.

CD22_HUMAN
NC score	0.030391 (rank : 36)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	27	Target Neighborhood Hits	365	Shared Neighborhood Hits	10
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

DYHC_MOUSE
NC score	0.025480 (rank : 37)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	27	Target Neighborhood Hits	729	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.025458 (rank : 38)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	27	Target Neighborhood Hits	733	Shared Neighborhood Hits	12
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

ZN452_HUMAN
NC score	0.024960 (rank : 39)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	27	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q6R2W3, Q2NKL9, Q5SRJ3, Q8TCN2, Q96PW3	Gene names	ZNF452, KIAA1925
Domain Architecture	No domain graphic available
Description	Protein ZNF452.

SETX_HUMAN
NC score	0.021439 (rank : 40)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	27	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ARS2_HUMAN
NC score	0.017566 (rank : 41)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	27	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

E41L3_HUMAN
NC score	0.016232 (rank : 42)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	27	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

SETB1_HUMAN
NC score	0.004817 (rank : 43)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	27	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

HDGR3_HUMAN
NC score	0.004746 (rank : 44)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	27	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

RASA1_HUMAN
NC score	0.003383 (rank : 45)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	27	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CHK2_HUMAN
NC score	0.000371 (rank : 46)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	27	Target Neighborhood Hits	859	Shared Neighborhood Hits	6
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).