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Network neighborhood for query Sequence : CA048_HUMAN

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CA048_HUMAN
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CA048_HUMAN
θ value	1.08415e-162 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

CA048_MOUSE
θ value	2.6227e-108 (rank : 2)	NC score	0.986966 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K305	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf48 homolog.

DLG5_HUMAN
θ value	0.163984 (rank : 3)	NC score	0.030395 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	1088	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

BACE1_HUMAN
θ value	0.62314 (rank : 4)	NC score	0.075557 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5	Gene names	BACE1, BACE
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

BACE1_MOUSE
θ value	0.62314 (rank : 5)	NC score	0.075485 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56818, Q544D0	Gene names	Bace1, Bace
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

ZN335_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.005799 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	973	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

LYRIC_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.033457 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

NUF2_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.030087 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	585	Shared Neighborhood Hits	6
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

SWP70_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.014476 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	973	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NUF2_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.018117 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	661	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

PCDA5_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.003503 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

NALP6_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.008940 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

RHG05_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.015145 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.014837 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

Hits sorted by NC score

CA048_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.08415e-162 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

CA048_MOUSE
NC score	0.986966 (rank : 2)	θ value	2.6227e-108 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K305	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf48 homolog.

BACE1_HUMAN
NC score	0.075557 (rank : 3)	θ value	0.62314 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5	Gene names	BACE1, BACE
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

BACE1_MOUSE
NC score	0.075485 (rank : 4)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P56818, Q544D0	Gene names	Bace1, Bace
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

LYRIC_HUMAN
NC score	0.033457 (rank : 5)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

DLG5_HUMAN
NC score	0.030395 (rank : 6)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	1088	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

NUF2_MOUSE
NC score	0.030087 (rank : 7)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	585	Shared Neighborhood Hits	6
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

NUF2_HUMAN
NC score	0.018117 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	661	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

RHG05_HUMAN
NC score	0.015145 (rank : 9)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
NC score	0.014837 (rank : 10)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SWP70_HUMAN
NC score	0.014476 (rank : 11)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	973	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NALP6_HUMAN
NC score	0.008940 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

ZN335_HUMAN
NC score	0.005799 (rank : 13)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	973	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

PCDA5_HUMAN
NC score	0.003503 (rank : 14)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).