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Network neighborhood for query Sequence : CCS_HUMAN

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CCS_HUMAN
SwissProt Accessions	O14618	Gene names	CCS
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CCS_HUMAN
θ value	2.26059e-160 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	O14618	Gene names	CCS
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).

CCS_MOUSE
θ value	2.19974e-139 (rank : 2)	NC score	0.997604 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WU84, Q9CRJ9	Gene names	Ccs, Ccsd
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).

SODC_MOUSE
θ value	8.61488e-35 (rank : 3)	NC score	0.902782 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P08228	Gene names	Sod1
Domain Architecture
Description	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1).

SODC_HUMAN
θ value	4.27553e-34 (rank : 4)	NC score	0.900624 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P00441, Q16669, Q16711, Q16838, Q16839, Q16840	Gene names	SOD1
Domain Architecture
Description	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1).

SODE_HUMAN
θ value	6.20254e-17 (rank : 5)	NC score	0.753638 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P08294, Q5U781, Q6FHA2	Gene names	SOD3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

SODE_MOUSE
θ value	2.60593e-15 (rank : 6)	NC score	0.734846 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O09164	Gene names	Sod3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

ATP7B_HUMAN
θ value	0.0431538 (rank : 7)	NC score	0.083460 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	P35670, Q16318, Q16319, Q4U3V3, Q59FJ9, Q5T7X7	Gene names	ATP7B, PWD, WC1, WND
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein).

ATOX1_MOUSE
θ value	0.0563607 (rank : 8)	NC score	0.235133 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O08997	Gene names	Atox1
Domain Architecture
Description	Copper transport protein ATOX1 (Metal transport protein ATX1).

ATOX1_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.234922 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O00244, Q56AP3	Gene names	ATOX1, HAH1
Domain Architecture
Description	Copper transport protein ATOX1 (Metal transport protein ATX1).

ATP7A_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.082709 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q64430, O35101, P97422, Q64431	Gene names	Atp7a, Mnk
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein homolog).

RAG1_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.029589 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

ATP7B_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.072737 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q64446	Gene names	Atp7b, Wnd
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein homolog).

ATP7A_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.070933 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q04656, O00227, O00745, Q9BYY8	Gene names	ATP7A, MC1, MNK
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein).

OGG1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.015441 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

Hits sorted by NC score

CCS_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.26059e-160 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	O14618	Gene names	CCS
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).

CCS_MOUSE
NC score	0.997604 (rank : 2)	θ value	2.19974e-139 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WU84, Q9CRJ9	Gene names	Ccs, Ccsd
Domain Architecture
Description	Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone).

SODC_MOUSE
NC score	0.902782 (rank : 3)	θ value	8.61488e-35 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	6
SwissProt Accessions	P08228	Gene names	Sod1
Domain Architecture
Description	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1).

SODC_HUMAN
NC score	0.900624 (rank : 4)	θ value	4.27553e-34 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	P00441, Q16669, Q16711, Q16838, Q16839, Q16840	Gene names	SOD1
Domain Architecture
Description	Superoxide dismutase [Cu-Zn] (EC 1.15.1.1).

SODE_HUMAN
NC score	0.753638 (rank : 5)	θ value	6.20254e-17 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P08294, Q5U781, Q6FHA2	Gene names	SOD3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

SODE_MOUSE
NC score	0.734846 (rank : 6)	θ value	2.60593e-15 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	O09164	Gene names	Sod3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

ATOX1_MOUSE
NC score	0.235133 (rank : 7)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O08997	Gene names	Atox1
Domain Architecture
Description	Copper transport protein ATOX1 (Metal transport protein ATX1).

ATOX1_HUMAN
NC score	0.234922 (rank : 8)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	4	Shared Neighborhood Hits	4
SwissProt Accessions	O00244, Q56AP3	Gene names	ATOX1, HAH1
Domain Architecture
Description	Copper transport protein ATOX1 (Metal transport protein ATX1).

ATP7B_HUMAN
NC score	0.083460 (rank : 9)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	P35670, Q16318, Q16319, Q4U3V3, Q59FJ9, Q5T7X7	Gene names	ATP7B, PWD, WC1, WND
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein).

ATP7A_MOUSE
NC score	0.082709 (rank : 10)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q64430, O35101, P97422, Q64431	Gene names	Atp7a, Mnk
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein homolog).

ATP7B_MOUSE
NC score	0.072737 (rank : 11)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q64446	Gene names	Atp7b, Wnd
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein homolog).

ATP7A_HUMAN
NC score	0.070933 (rank : 12)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q04656, O00227, O00745, Q9BYY8	Gene names	ATP7A, MC1, MNK
Domain Architecture
Description	Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkes disease-associated protein).

RAG1_MOUSE
NC score	0.029589 (rank : 13)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

OGG1_HUMAN
NC score	0.015441 (rank : 14)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].