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Network neighborhood for query Sequence : PSMD1_HUMAN

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PSMD1_HUMAN
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSMD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).

PSMD1_MOUSE
θ value	0 (rank : 2)	NC score	0.998682 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q3TXS7	Gene names	Psmd1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1).

PSMD2_HUMAN
θ value	8.67504e-11 (rank : 3)	NC score	0.388326 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

PSMD2_MOUSE
θ value	1.133e-10 (rank : 4)	NC score	0.383378 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

DMD_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.037968 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SMCA1_HUMAN
θ value	0.163984 (rank : 6)	NC score	0.031230 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

DMD_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.036133 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	1111	Shared Neighborhood Hits	19
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DNMT1_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.056084 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

RTN4_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.060197 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	357	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RTN4_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.056962 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

TCRG1_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.048873 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	929	Shared Neighborhood Hits	21
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	1.06291 (rank : 12)	NC score	0.048726 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	947	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TPM4_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.025207 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	703	Shared Neighborhood Hits	11
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

NOP14_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.034679 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	573	Shared Neighborhood Hits	15
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

XRCC4_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.051514 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q924T3, Q8BKC9, Q8BU02, Q9D6U6	Gene names	Xrcc4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

MINT_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.026397 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	1291	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CCNI_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.018566 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

DOHH_MOUSE
θ value	4.03905 (rank : 18)	NC score	0.042673 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LN9, Q8BNT3, Q8BTD5	Gene names	Dohh
Domain Architecture	No domain graphic available
Description	Deoxyhypusine hydroxylase (EC 1.14.99.29) (Deoxyhypusine monooxygenase).

KI21A_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.007890 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	1543	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PHF20_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.029745 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	513	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

ZN198_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.017189 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

ANR12_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.017251 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	1081	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ODBA_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.029111 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	P12694, Q16034, Q16472	Gene names	BCKDHA
Domain Architecture
Description	2-oxoisovalerate dehydrogenase alpha subunit, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A).

PESC_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.032496 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

PHF3_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.033237 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RIC8B_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.025652 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XE1, Q58L65	Gene names	Ric8b
Domain Architecture	No domain graphic available
Description	Synembryn-B (Protein Ric-8B).

CK5P2_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.015814 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	1151	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

DIDO1_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.025542 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	960	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DNJC8_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.027349 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	380	Shared Neighborhood Hits	15
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.026911 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

GCC2_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.014198 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	1619	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MYLK_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.001446 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	1328	Shared Neighborhood Hits	5
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

TITIN_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.004919 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BPA1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.014107 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	1477	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCNF_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.010782 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

JHD2C_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.012381 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

KIF14_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.009068 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	732	Shared Neighborhood Hits	13
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

NRX1A_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.014802 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.014836 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PRP40_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.038301 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	442	Shared Neighborhood Hits	18
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.039685 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

STK36_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.001764 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	877	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

Hits sorted by NC score

PSMD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q99460, Q53TI2, Q6GMU5, Q6P2P4, Q6PJM7, Q6PKG9, Q86VU1, Q8IV79	Gene names	PSMD1
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112).

PSMD1_MOUSE
NC score	0.998682 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q3TXS7	Gene names	Psmd1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1).

PSMD2_HUMAN
NC score	0.388326 (rank : 3)	θ value	8.67504e-11 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

PSMD2_MOUSE
NC score	0.383378 (rank : 4)	θ value	1.133e-10 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

RTN4_HUMAN
NC score	0.060197 (rank : 5)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	357	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RTN4_MOUSE
NC score	0.056962 (rank : 6)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

DNMT1_HUMAN
NC score	0.056084 (rank : 7)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

XRCC4_MOUSE
NC score	0.051514 (rank : 8)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q924T3, Q8BKC9, Q8BU02, Q9D6U6	Gene names	Xrcc4
Domain Architecture
Description	DNA-repair protein XRCC4 (X-ray repair cross-complementing protein 4).

TCRG1_HUMAN
NC score	0.048873 (rank : 9)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	929	Shared Neighborhood Hits	21
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.048726 (rank : 10)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	947	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

DOHH_MOUSE
NC score	0.042673 (rank : 11)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LN9, Q8BNT3, Q8BTD5	Gene names	Dohh
Domain Architecture	No domain graphic available
Description	Deoxyhypusine hydroxylase (EC 1.14.99.29) (Deoxyhypusine monooxygenase).

PRP40_MOUSE
NC score	0.039685 (rank : 12)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

PRP40_HUMAN
NC score	0.038301 (rank : 13)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	442	Shared Neighborhood Hits	18
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

DMD_HUMAN
NC score	0.037968 (rank : 14)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
NC score	0.036133 (rank : 15)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	1111	Shared Neighborhood Hits	19
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

NOP14_HUMAN
NC score	0.034679 (rank : 16)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	573	Shared Neighborhood Hits	15
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PHF3_HUMAN
NC score	0.033237 (rank : 17)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PESC_HUMAN
NC score	0.032496 (rank : 18)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

SMCA1_HUMAN
NC score	0.031230 (rank : 19)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

PHF20_MOUSE
NC score	0.029745 (rank : 20)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	513	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

ODBA_HUMAN
NC score	0.029111 (rank : 21)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	P12694, Q16034, Q16472	Gene names	BCKDHA
Domain Architecture
Description	2-oxoisovalerate dehydrogenase alpha subunit, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A).

DNJC8_HUMAN
NC score	0.027349 (rank : 22)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	380	Shared Neighborhood Hits	15
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

DNJC8_MOUSE
NC score	0.026911 (rank : 23)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

MINT_HUMAN
NC score	0.026397 (rank : 24)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	1291	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RIC8B_MOUSE
NC score	0.025652 (rank : 25)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XE1, Q58L65	Gene names	Ric8b
Domain Architecture	No domain graphic available
Description	Synembryn-B (Protein Ric-8B).

DIDO1_HUMAN
NC score	0.025542 (rank : 26)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	960	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TPM4_MOUSE
NC score	0.025207 (rank : 27)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	703	Shared Neighborhood Hits	11
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

CCNI_HUMAN
NC score	0.018566 (rank : 28)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

ANR12_HUMAN
NC score	0.017251 (rank : 29)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	1081	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ZN198_HUMAN
NC score	0.017189 (rank : 30)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

CK5P2_MOUSE
NC score	0.015814 (rank : 31)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	1151	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

NRX1A_MOUSE
NC score	0.014836 (rank : 32)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_HUMAN
NC score	0.014802 (rank : 33)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

GCC2_MOUSE
NC score	0.014198 (rank : 34)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	1619	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

BPA1_MOUSE
NC score	0.014107 (rank : 35)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	1477	Shared Neighborhood Hits	14
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

JHD2C_HUMAN
NC score	0.012381 (rank : 36)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

CCNF_MOUSE
NC score	0.010782 (rank : 37)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

KIF14_HUMAN
NC score	0.009068 (rank : 38)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	732	Shared Neighborhood Hits	13
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

KI21A_HUMAN
NC score	0.007890 (rank : 39)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	1543	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

TITIN_HUMAN
NC score	0.004919 (rank : 40)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

STK36_MOUSE
NC score	0.001764 (rank : 41)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	877	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

MYLK_HUMAN
NC score	0.001446 (rank : 42)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	1328	Shared Neighborhood Hits	5
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).