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Network neighborhood for query Sequence : SPESP_MOUSE

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SPESP_MOUSE
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPESP_MOUSE
θ value	3.47952e-169 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

SPESP_HUMAN
θ value	7.24236e-58 (rank : 2)	NC score	0.910272 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UW49, Q8NG22, Q8WVH8	Gene names	SPESP1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor (SP-ESP) (Equatorial segment protein) (ESP) (Glycosylated 38 kDa sperm protein C-7/8).

ATS12_HUMAN
θ value	0.0113563 (rank : 3)	NC score	0.036952 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	251	Shared Neighborhood Hits	3
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

SEPT9_HUMAN
θ value	0.0961366 (rank : 4)	NC score	0.037726 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	706	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TITIN_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.014522 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	2923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZSCA5_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.007167 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	862	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

CDC5L_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.050101 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

PKHA6_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.027051 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	591	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CAC1B_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.013303 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

FA47B_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.030744 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

LNX1_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.016385 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	379	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

CDC5L_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.045965 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

E41L3_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.012876 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

FLIP1_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.010039 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	1176	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GDIS_MOUSE
θ value	4.03905 (rank : 15)	NC score	0.024736 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q61599, Q3TEB3	Gene names	Arhgdib, Gdid4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (D4).

UBP26_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.020755 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

PTCD1_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.029699 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

WNK1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.005927 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	1158	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

GP152_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.007962 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	636	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

TRIM5_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.005899 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	424	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

Hits sorted by NC score

SPESP_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.47952e-169 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

SPESP_HUMAN
NC score	0.910272 (rank : 2)	θ value	7.24236e-58 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UW49, Q8NG22, Q8WVH8	Gene names	SPESP1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor (SP-ESP) (Equatorial segment protein) (ESP) (Glycosylated 38 kDa sperm protein C-7/8).

CDC5L_HUMAN
NC score	0.050101 (rank : 3)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

CDC5L_MOUSE
NC score	0.045965 (rank : 4)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

SEPT9_HUMAN
NC score	0.037726 (rank : 5)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	706	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ATS12_HUMAN
NC score	0.036952 (rank : 6)	θ value	0.0113563 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	251	Shared Neighborhood Hits	3
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

FA47B_HUMAN
NC score	0.030744 (rank : 7)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

PTCD1_HUMAN
NC score	0.029699 (rank : 8)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	O75127, Q66K60, Q9UDV2	Gene names	PTCD1, KIAA0632
Domain Architecture	No domain graphic available
Description	Pentatricopeptide repeat protein 1.

PKHA6_MOUSE
NC score	0.027051 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	591	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GDIS_MOUSE
NC score	0.024736 (rank : 10)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q61599, Q3TEB3	Gene names	Arhgdib, Gdid4
Domain Architecture
Description	Rho GDP-dissociation inhibitor 2 (Rho GDI 2) (Rho-GDI beta) (D4).

UBP26_HUMAN
NC score	0.020755 (rank : 11)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

LNX1_HUMAN
NC score	0.016385 (rank : 12)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	379	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TITIN_HUMAN
NC score	0.014522 (rank : 13)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	2923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CAC1B_MOUSE
NC score	0.013303 (rank : 14)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

E41L3_MOUSE
NC score	0.012876 (rank : 15)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

FLIP1_MOUSE
NC score	0.010039 (rank : 16)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	1176	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GP152_HUMAN
NC score	0.007962 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	636	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

ZSCA5_HUMAN
NC score	0.007167 (rank : 18)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	862	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BUG6	Gene names	ZSCAN5, ZNF495
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 5 (Zinc finger protein 495).

WNK1_HUMAN
NC score	0.005927 (rank : 19)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	1158	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

TRIM5_HUMAN
NC score	0.005899 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	424	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).