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Network neighborhood for query Sequence : NLGN2_HUMAN

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NLGN2_HUMAN
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NLGN1_HUMAN
θ value	0 (rank : 1)	NC score	0.994971 (rank : 5)
Query Neighborhood Hits	55	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_MOUSE
θ value	0 (rank : 2)	NC score	0.994882 (rank : 7)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	55	Target Neighborhood Hits	55	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	0 (rank : 4)	NC score	0.999592 (rank : 2)
Query Neighborhood Hits	55	Target Neighborhood Hits	49	Shared Neighborhood Hits	46
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN3_HUMAN
θ value	0 (rank : 5)	NC score	0.994860 (rank : 8)
Query Neighborhood Hits	55	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN3_MOUSE
θ value	0 (rank : 6)	NC score	0.994902 (rank : 6)
Query Neighborhood Hits	55	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGNX_HUMAN
θ value	0 (rank : 7)	NC score	0.995063 (rank : 4)
Query Neighborhood Hits	55	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
θ value	0 (rank : 8)	NC score	0.995180 (rank : 3)
Query Neighborhood Hits	55	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

CHLE_MOUSE
θ value	2.47191e-82 (rank : 9)	NC score	0.947873 (rank : 15)
Query Neighborhood Hits	55	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_HUMAN
θ value	3.56943e-81 (rank : 10)	NC score	0.948154 (rank : 14)
Query Neighborhood Hits	55	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

ACES_MOUSE
θ value	6.08852e-81 (rank : 11)	NC score	0.949893 (rank : 11)
Query Neighborhood Hits	55	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
θ value	3.0217e-80 (rank : 12)	NC score	0.949148 (rank : 12)
Query Neighborhood Hits	55	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

EST1_HUMAN
θ value	4.08394e-77 (rank : 13)	NC score	0.934776 (rank : 16)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

EST2_HUMAN
θ value	4.08394e-77 (rank : 14)	NC score	0.950852 (rank : 10)
Query Neighborhood Hits	55	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

CEL_MOUSE
θ value	1.45253e-74 (rank : 15)	NC score	0.953374 (rank : 9)
Query Neighborhood Hits	55	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST22_MOUSE
θ value	7.20884e-74 (rank : 16)	NC score	0.934475 (rank : 17)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CES3_MOUSE
θ value	6.10265e-73 (rank : 17)	NC score	0.932833 (rank : 18)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

CEL_HUMAN
θ value	3.95564e-72 (rank : 18)	NC score	0.723685 (rank : 23)
Query Neighborhood Hits	55	Target Neighborhood Hits	896	Shared Neighborhood Hits	39
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST31_MOUSE
θ value	3.34864e-71 (rank : 19)	NC score	0.948628 (rank : 13)
Query Neighborhood Hits	55	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST1_MOUSE
θ value	6.31527e-70 (rank : 20)	NC score	0.930267 (rank : 20)
Query Neighborhood Hits	55	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

ESTN_MOUSE
θ value	1.83746e-69 (rank : 21)	NC score	0.932724 (rank : 19)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

THYG_MOUSE
θ value	2.041e-52 (rank : 22)	NC score	0.812449 (rank : 21)
Query Neighborhood Hits	55	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
θ value	2.50074e-42 (rank : 23)	NC score	0.793576 (rank : 22)
Query Neighborhood Hits	55	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TULP4_HUMAN
θ value	0.00665767 (rank : 24)	NC score	0.044921 (rank : 31)
Query Neighborhood Hits	55	Target Neighborhood Hits	426	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

DPP8_HUMAN
θ value	0.00869519 (rank : 25)	NC score	0.063738 (rank : 27)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
θ value	0.00869519 (rank : 26)	NC score	0.061681 (rank : 28)
Query Neighborhood Hits	55	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

EP400_HUMAN
θ value	0.0431538 (rank : 27)	NC score	0.021521 (rank : 35)
Query Neighborhood Hits	55	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

TPO_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.044672 (rank : 32)
Query Neighborhood Hits	55	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

DPP9_HUMAN
θ value	0.163984 (rank : 29)	NC score	0.056368 (rank : 29)
Query Neighborhood Hits	55	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

TCGAP_HUMAN
θ value	0.163984 (rank : 30)	NC score	0.014794 (rank : 40)
Query Neighborhood Hits	55	Target Neighborhood Hits	872	Shared Neighborhood Hits	17
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

DPP9_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.049900 (rank : 30)
Query Neighborhood Hits	55	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

TULP4_MOUSE
θ value	0.365318 (rank : 32)	NC score	0.038632 (rank : 33)
Query Neighborhood Hits	55	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

NACAM_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.014888 (rank : 39)
Query Neighborhood Hits	55	Target Neighborhood Hits	1866	Shared Neighborhood Hits	23
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BAG3_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.015897 (rank : 38)
Query Neighborhood Hits	55	Target Neighborhood Hits	513	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PLXB1_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.012421 (rank : 43)
Query Neighborhood Hits	55	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

BAT2_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.024800 (rank : 34)
Query Neighborhood Hits	55	Target Neighborhood Hits	931	Shared Neighborhood Hits	20
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TRPV4_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.009702 (rank : 47)
Query Neighborhood Hits	55	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

OGFR_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.014613 (rank : 41)
Query Neighborhood Hits	55	Target Neighborhood Hits	1582	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

LAG3_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.015950 (rank : 37)
Query Neighborhood Hits	55	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

BAT2_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.021282 (rank : 36)
Query Neighborhood Hits	55	Target Neighborhood Hits	947	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GP108_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.011794 (rank : 44)
Query Neighborhood Hits	55	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

MLL3_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.005327 (rank : 51)
Query Neighborhood Hits	55	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TITIN_HUMAN
θ value	4.03905 (rank : 43)	NC score	-0.000315 (rank : 57)
Query Neighborhood Hits	55	Target Neighborhood Hits	2923	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZEP1_HUMAN
θ value	4.03905 (rank : 44)	NC score	-0.000667 (rank : 58)
Query Neighborhood Hits	55	Target Neighborhood Hits	1036	Shared Neighborhood Hits	9
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

ATP9B_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.003277 (rank : 53)
Query Neighborhood Hits	55	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P98195, Q99LI3	Gene names	Atp9b
Domain Architecture
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

EPN2_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.007682 (rank : 48)
Query Neighborhood Hits	55	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

SON_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.005897 (rank : 49)
Query Neighborhood Hits	55	Target Neighborhood Hits	1568	Shared Neighborhood Hits	20
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BCL9_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.010268 (rank : 46)
Query Neighborhood Hits	55	Target Neighborhood Hits	1008	Shared Neighborhood Hits	20
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.014195 (rank : 42)
Query Neighborhood Hits	55	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CO4A2_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.002375 (rank : 56)
Query Neighborhood Hits	55	Target Neighborhood Hits	492	Shared Neighborhood Hits	11
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

KCNQ1_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.002429 (rank : 55)
Query Neighborhood Hits	55	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PTPRO_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.002950 (rank : 54)
Query Neighborhood Hits	55	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

RKHD1_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.010374 (rank : 45)
Query Neighborhood Hits	55	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SSBP4_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.005438 (rank : 50)
Query Neighborhood Hits	55	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

USH1C_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.003602 (rank : 52)
Query Neighborhood Hits	55	Target Neighborhood Hits	557	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

AAAD_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.208575 (rank : 24)
Query Neighborhood Hits	55	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.117110 (rank : 25)
Query Neighborhood Hits	55	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

SMR3B_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.090712 (rank : 26)
Query Neighborhood Hits	55	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

Hits sorted by NC score

NLGN2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	55	Target Neighborhood Hits	55	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
NC score	0.999592 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	55	Target Neighborhood Hits	49	Shared Neighborhood Hits	46
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGNY_HUMAN
NC score	0.995180 (rank : 3)	θ value	0 (rank : 8)
Query Neighborhood Hits	55	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGNX_HUMAN
NC score	0.995063 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	55	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGN1_HUMAN
NC score	0.994971 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	55	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN3_MOUSE
NC score	0.994902 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	55	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN1_MOUSE
NC score	0.994882 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN3_HUMAN
NC score	0.994860 (rank : 8)	θ value	0 (rank : 5)
Query Neighborhood Hits	55	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

CEL_MOUSE
NC score	0.953374 (rank : 9)	θ value	1.45253e-74 (rank : 15)
Query Neighborhood Hits	55	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST2_HUMAN
NC score	0.950852 (rank : 10)	θ value	4.08394e-77 (rank : 14)
Query Neighborhood Hits	55	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

ACES_MOUSE
NC score	0.949893 (rank : 11)	θ value	6.08852e-81 (rank : 11)
Query Neighborhood Hits	55	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
NC score	0.949148 (rank : 12)	θ value	3.0217e-80 (rank : 12)
Query Neighborhood Hits	55	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

EST31_MOUSE
NC score	0.948628 (rank : 13)	θ value	3.34864e-71 (rank : 19)
Query Neighborhood Hits	55	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

CHLE_HUMAN
NC score	0.948154 (rank : 14)	θ value	3.56943e-81 (rank : 10)
Query Neighborhood Hits	55	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_MOUSE
NC score	0.947873 (rank : 15)	θ value	2.47191e-82 (rank : 9)
Query Neighborhood Hits	55	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST1_HUMAN
NC score	0.934776 (rank : 16)	θ value	4.08394e-77 (rank : 13)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

EST22_MOUSE
NC score	0.934475 (rank : 17)	θ value	7.20884e-74 (rank : 16)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CES3_MOUSE
NC score	0.932833 (rank : 18)	θ value	6.10265e-73 (rank : 17)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

ESTN_MOUSE
NC score	0.932724 (rank : 19)	θ value	1.83746e-69 (rank : 21)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST1_MOUSE
NC score	0.930267 (rank : 20)	θ value	6.31527e-70 (rank : 20)
Query Neighborhood Hits	55	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

THYG_MOUSE
NC score	0.812449 (rank : 21)	θ value	2.041e-52 (rank : 22)
Query Neighborhood Hits	55	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
NC score	0.793576 (rank : 22)	θ value	2.50074e-42 (rank : 23)
Query Neighborhood Hits	55	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

CEL_HUMAN
NC score	0.723685 (rank : 23)	θ value	3.95564e-72 (rank : 18)
Query Neighborhood Hits	55	Target Neighborhood Hits	896	Shared Neighborhood Hits	39
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

AAAD_HUMAN
NC score	0.208575 (rank : 24)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	55	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
NC score	0.117110 (rank : 25)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	55	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

SMR3B_HUMAN
NC score	0.090712 (rank : 26)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	55	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

DPP8_HUMAN
NC score	0.063738 (rank : 27)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q6V1X1, Q7Z4C8, Q7Z4D3, Q7Z4E1, Q8IWG7, Q8NEM5, Q96JX1, Q9HBM2, Q9HBM3, Q9HBM4, Q9HBM5, Q9NXF4	Gene names	DPP8, DPRP1
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8) (Prolyl dipeptidase DPP8) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1).

DPP8_MOUSE
NC score	0.061681 (rank : 28)	θ value	0.00869519 (rank : 26)
Query Neighborhood Hits	55	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YA7, Q9D4G6	Gene names	Dpp8
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 8 (EC 3.4.14.5) (Dipeptidyl peptidase VIII) (DP8).

DPP9_HUMAN
NC score	0.056368 (rank : 29)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	55	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
NC score	0.049900 (rank : 30)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	55	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

TULP4_HUMAN
NC score	0.044921 (rank : 31)	θ value	0.00665767 (rank : 24)
Query Neighborhood Hits	55	Target Neighborhood Hits	426	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TPO_MOUSE
NC score	0.044672 (rank : 32)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	55	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TULP4_MOUSE
NC score	0.038632 (rank : 33)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	55	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

BAT2_HUMAN
NC score	0.024800 (rank : 34)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	55	Target Neighborhood Hits	931	Shared Neighborhood Hits	20
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EP400_HUMAN
NC score	0.021521 (rank : 35)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	55	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

BAT2_MOUSE
NC score	0.021282 (rank : 36)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	55	Target Neighborhood Hits	947	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

LAG3_MOUSE
NC score	0.015950 (rank : 37)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	55	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

BAG3_MOUSE
NC score	0.015897 (rank : 38)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	55	Target Neighborhood Hits	513	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

NACAM_MOUSE
NC score	0.014888 (rank : 39)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	55	Target Neighborhood Hits	1866	Shared Neighborhood Hits	23
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TCGAP_HUMAN
NC score	0.014794 (rank : 40)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	55	Target Neighborhood Hits	872	Shared Neighborhood Hits	17
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

OGFR_HUMAN
NC score	0.014613 (rank : 41)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	55	Target Neighborhood Hits	1582	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BCL9_MOUSE
NC score	0.014195 (rank : 42)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	55	Target Neighborhood Hits	770	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PLXB1_HUMAN
NC score	0.012421 (rank : 43)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	55	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

GP108_MOUSE
NC score	0.011794 (rank : 44)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	55	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

RKHD1_HUMAN
NC score	0.010374 (rank : 45)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	55	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BCL9_HUMAN
NC score	0.010268 (rank : 46)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	55	Target Neighborhood Hits	1008	Shared Neighborhood Hits	20
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

TRPV4_HUMAN
NC score	0.009702 (rank : 47)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	55	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

EPN2_HUMAN
NC score	0.007682 (rank : 48)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	55	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

SON_HUMAN
NC score	0.005897 (rank : 49)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	55	Target Neighborhood Hits	1568	Shared Neighborhood Hits	20
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SSBP4_HUMAN
NC score	0.005438 (rank : 50)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	55	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

MLL3_HUMAN
NC score	0.005327 (rank : 51)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	55	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

USH1C_MOUSE
NC score	0.003602 (rank : 52)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	55	Target Neighborhood Hits	557	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

ATP9B_MOUSE
NC score	0.003277 (rank : 53)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	55	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P98195, Q99LI3	Gene names	Atp9b
Domain Architecture
Description	Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1).

PTPRO_HUMAN
NC score	0.002950 (rank : 54)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	55	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

KCNQ1_MOUSE
NC score	0.002429 (rank : 55)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	55	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

CO4A2_MOUSE
NC score	0.002375 (rank : 56)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	55	Target Neighborhood Hits	492	Shared Neighborhood Hits	11
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

TITIN_HUMAN
NC score	-0.000315 (rank : 57)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	55	Target Neighborhood Hits	2923	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZEP1_HUMAN
NC score	-0.000667 (rank : 58)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	55	Target Neighborhood Hits	1036	Shared Neighborhood Hits	9
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).