Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CALX_HUMAN

For an explanation of this page, click here

CALX_HUMAN
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CALX_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CALX_MOUSE
θ value	0 (rank : 2)	NC score	0.991095 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	46
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CLGN_HUMAN
θ value	0 (rank : 3)	NC score	0.972220 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	111	Shared Neighborhood Hits	26
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

CLGN_MOUSE
θ value	0 (rank : 4)	NC score	0.966992 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	30
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CALR_HUMAN
θ value	9.76566e-63 (rank : 5)	NC score	0.890290 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CALR_MOUSE
θ value	2.17557e-62 (rank : 6)	NC score	0.892789 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CALR3_HUMAN
θ value	1.9192e-34 (rank : 7)	NC score	0.822332 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L12, Q96LN3	Gene names	CALR3, CRT2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

CALR3_MOUSE
θ value	3.3877e-31 (rank : 8)	NC score	0.811973 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D9Q6	Gene names	Calr3, Crt2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

H6ST3_HUMAN
θ value	0.00175202 (rank : 9)	NC score	0.106446 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

LEO1_MOUSE
θ value	0.0148317 (rank : 10)	NC score	0.090060 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	946	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

H6ST3_MOUSE
θ value	0.0431538 (rank : 11)	NC score	0.079186 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

CC47_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.069897 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	245	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

PEG3_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.017081 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	1101	Shared Neighborhood Hits	32
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TCAL5_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.069186 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	806	Shared Neighborhood Hits	51
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

UBP48_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.037488 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

NSBP1_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.095103 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	681	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

UBP48_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.036551 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

ADDA_MOUSE
θ value	0.279714 (rank : 18)	NC score	0.031274 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

IF2P_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.055291 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	889	Shared Neighborhood Hits	49
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

RBBP6_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.038700 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

AKA12_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.055321 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	825	Shared Neighborhood Hits	48
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

NRDC_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.058882 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

ACINU_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.039437 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	712	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BASP_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.066019 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DMXL2_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.020321 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	374	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

LARP1_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.055024 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

ACK1_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.007120 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	1140	Shared Neighborhood Hits	21
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

NASP_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.060516 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	709	Shared Neighborhood Hits	44
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SEC63_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.066859 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	601	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TITIN_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.011069 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	2923	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ERIC1_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.105207 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	364	Shared Neighborhood Hits	30
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

MAP1A_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.035272 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	1626	Shared Neighborhood Hits	52
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

VSX1_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.016143 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	356	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

CP39A_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.031758 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JKJ9	Gene names	Cyp39a1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1).

IWS1_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.055488 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SMRC1_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.025335 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

ACK1_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.006186 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	1080	Shared Neighborhood Hits	15
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

IWS1_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.060248 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	1258	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1143_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.035499 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

LEO1_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.071588 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	958	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SETD2_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.030545 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

TXND2_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.053587 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	828	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NALP5_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.034875 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	560	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PEG3_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.005873 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	800	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

SPEG_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.008076 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	1959	Shared Neighborhood Hits	29
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP8_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.021635 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	751	Shared Neighborhood Hits	38
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

GON4L_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.030545 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IRX2_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.022090 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	358	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

TR150_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.052365 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	468	Shared Neighborhood Hits	32
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ANR26_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.004840 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	1554	Shared Neighborhood Hits	23
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BAT2_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.018352 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	947	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

IF4G3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.025514 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.025435 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K0460_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.014692 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	357	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MLL2_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.010878 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	31
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PRKDC_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.010679 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

SEC63_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.059838 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	586	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

TSH2_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.011938 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

UACA_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.003793 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

USP9X_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.021822 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	12
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

CLMN_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.011033 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

FLIP1_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.008275 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	1405	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MCES_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.029707 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

MDN1_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.044150 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	662	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NFH_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.016290 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	1242	Shared Neighborhood Hits	48
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PDE4D_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.011289 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

USP9X_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.021680 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	171	Shared Neighborhood Hits	13
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

CCDC9_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.058061 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CCDC9_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.042498 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	196	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CF010_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.054627 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CJ078_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.034449 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	559	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CP39A_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.017426 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYL5, Q96FW5	Gene names	CYP39A1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1).

ERRFI_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.022483 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

HRX_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.014272 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	825	Shared Neighborhood Hits	24
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LRMP_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.013024 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

MINT_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.019296 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	1514	Shared Neighborhood Hits	39
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NOL3_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.024495 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

PDE4D_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.011784 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PEPL_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.009857 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	1105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PER2_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.006603 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	325	Shared Neighborhood Hits	7
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PSMD2_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.010833 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

TNNT1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.018728 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	211	Shared Neighborhood Hits	15
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

ASXL1_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.014305 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CAC1C_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.005486 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CCD96_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.032005 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	704	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CS007_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.013458 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	464	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DSPP_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.031655 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	491	Shared Neighborhood Hits	29
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

E41L2_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.008027 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	459	Shared Neighborhood Hits	28
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ENPL_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.008516 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

RBBP5_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.018254 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	372	Shared Neighborhood Hits	13
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

RGP1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.034484 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	105	Shared Neighborhood Hits	21
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

SH23A_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.006369 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

SLK_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.003606 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	1775	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.002811 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	1798	Shared Neighborhood Hits	33
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SPEG_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.003425 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	1762	Shared Neighborhood Hits	23
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TTC1_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.019893 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	417	Shared Neighborhood Hits	23
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

NSBP1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.053486 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	251	Shared Neighborhood Hits	32
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMA_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.072670 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.058428 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.058121 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	111	Shared Neighborhood Hits	19
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

Hits sorted by NC score

CALX_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CALX_MOUSE
NC score	0.991095 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	46
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CLGN_HUMAN
NC score	0.972220 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	111	Shared Neighborhood Hits	26
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

CLGN_MOUSE
NC score	0.966992 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	142	Shared Neighborhood Hits	30
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CALR_MOUSE
NC score	0.892789 (rank : 5)	θ value	2.17557e-62 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CALR_HUMAN
NC score	0.890290 (rank : 6)	θ value	9.76566e-63 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CALR3_HUMAN
NC score	0.822332 (rank : 7)	θ value	1.9192e-34 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L12, Q96LN3	Gene names	CALR3, CRT2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

CALR3_MOUSE
NC score	0.811973 (rank : 8)	θ value	3.3877e-31 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D9Q6	Gene names	Calr3, Crt2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

H6ST3_HUMAN
NC score	0.106446 (rank : 9)	θ value	0.00175202 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	66	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

ERIC1_HUMAN
NC score	0.105207 (rank : 10)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	364	Shared Neighborhood Hits	30
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

NSBP1_MOUSE
NC score	0.095103 (rank : 11)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	681	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

LEO1_MOUSE
NC score	0.090060 (rank : 12)	θ value	0.0148317 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	946	Shared Neighborhood Hits	51
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

H6ST3_MOUSE
NC score	0.079186 (rank : 13)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QYK4	Gene names	Hs6st3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3) (mHS6ST- 3).

PTMA_HUMAN
NC score	0.072670 (rank : 14)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

LEO1_HUMAN
NC score	0.071588 (rank : 15)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	958	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CC47_MOUSE
NC score	0.069897 (rank : 16)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	245	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

TCAL5_HUMAN
NC score	0.069186 (rank : 17)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	806	Shared Neighborhood Hits	51
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

SEC63_MOUSE
NC score	0.066859 (rank : 18)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	601	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

BASP_MOUSE
NC score	0.066019 (rank : 19)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	260	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

NASP_HUMAN
NC score	0.060516 (rank : 20)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	709	Shared Neighborhood Hits	44
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

IWS1_MOUSE
NC score	0.060248 (rank : 21)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	1258	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SEC63_HUMAN
NC score	0.059838 (rank : 22)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	586	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

NRDC_MOUSE
NC score	0.058882 (rank : 23)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

PTMA_MOUSE
NC score	0.058428 (rank : 24)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
NC score	0.058121 (rank : 25)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	111	Shared Neighborhood Hits	19
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

CCDC9_HUMAN
NC score	0.058061 (rank : 26)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

IWS1_HUMAN
NC score	0.055488 (rank : 27)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKA12_HUMAN
NC score	0.055321 (rank : 28)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	825	Shared Neighborhood Hits	48
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

IF2P_HUMAN
NC score	0.055291 (rank : 29)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	889	Shared Neighborhood Hits	49
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LARP1_HUMAN
NC score	0.055024 (rank : 30)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

CF010_HUMAN
NC score	0.054627 (rank : 31)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

TXND2_MOUSE
NC score	0.053587 (rank : 32)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	828	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NSBP1_HUMAN
NC score	0.053486 (rank : 33)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	251	Shared Neighborhood Hits	32
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

TR150_MOUSE
NC score	0.052365 (rank : 34)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	468	Shared Neighborhood Hits	32
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

MDN1_HUMAN
NC score	0.044150 (rank : 35)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	662	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

CCDC9_MOUSE
NC score	0.042498 (rank : 36)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	196	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

ACINU_MOUSE
NC score	0.039437 (rank : 37)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	712	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RBBP6_HUMAN
NC score	0.038700 (rank : 38)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

UBP48_HUMAN
NC score	0.037488 (rank : 39)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.036551 (rank : 40)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

K1143_MOUSE
NC score	0.035499 (rank : 41)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

MAP1A_HUMAN
NC score	0.035272 (rank : 42)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	1626	Shared Neighborhood Hits	52
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NALP5_MOUSE
NC score	0.034875 (rank : 43)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	560	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RGP1_MOUSE
NC score	0.034484 (rank : 44)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	105	Shared Neighborhood Hits	21
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CJ078_MOUSE
NC score	0.034449 (rank : 45)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	559	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CCD96_MOUSE
NC score	0.032005 (rank : 46)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	704	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CP39A_MOUSE
NC score	0.031758 (rank : 47)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JKJ9	Gene names	Cyp39a1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (mCYP39A1).

DSPP_MOUSE
NC score	0.031655 (rank : 48)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	491	Shared Neighborhood Hits	29
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ADDA_MOUSE
NC score	0.031274 (rank : 49)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

GON4L_MOUSE
NC score	0.030545 (rank : 50)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SETD2_HUMAN
NC score	0.030545 (rank : 51)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	412	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

MCES_HUMAN
NC score	0.029707 (rank : 52)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

IF4G3_HUMAN
NC score	0.025514 (rank : 53)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
NC score	0.025435 (rank : 54)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

SMRC1_MOUSE
NC score	0.025335 (rank : 55)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	459	Shared Neighborhood Hits	30
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

NOL3_MOUSE
NC score	0.024495 (rank : 56)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	97	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

ERRFI_HUMAN
NC score	0.022483 (rank : 57)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

IRX2_HUMAN
NC score	0.022090 (rank : 58)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	358	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

USP9X_HUMAN
NC score	0.021822 (rank : 59)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	12
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
NC score	0.021680 (rank : 60)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	171	Shared Neighborhood Hits	13
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP8_HUMAN
NC score	0.021635 (rank : 61)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	751	Shared Neighborhood Hits	38
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

DMXL2_HUMAN
NC score	0.020321 (rank : 62)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	374	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

TTC1_HUMAN
NC score	0.019893 (rank : 63)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	417	Shared Neighborhood Hits	23
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

MINT_MOUSE
NC score	0.019296 (rank : 64)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	1514	Shared Neighborhood Hits	39
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TNNT1_HUMAN
NC score	0.018728 (rank : 65)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	211	Shared Neighborhood Hits	15
SwissProt Accessions	P13805, O95472, Q16061	Gene names	TNNT1, TNT
Domain Architecture	No domain graphic available
Description	Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT).

BAT2_MOUSE
NC score	0.018352 (rank : 66)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	947	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RBBP5_HUMAN
NC score	0.018254 (rank : 67)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	372	Shared Neighborhood Hits	13
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

CP39A_HUMAN
NC score	0.017426 (rank : 68)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYL5, Q96FW5	Gene names	CYP39A1
Domain Architecture
Description	Cytochrome P450 39A1 (EC 1.14.13.99) (24-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1).

PEG3_MOUSE
NC score	0.017081 (rank : 69)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	1101	Shared Neighborhood Hits	32
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

NFH_HUMAN
NC score	0.016290 (rank : 70)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	1242	Shared Neighborhood Hits	48
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

VSX1_MOUSE
NC score	0.016143 (rank : 71)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	356	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

K0460_HUMAN
NC score	0.014692 (rank : 72)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	357	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ASXL1_MOUSE
NC score	0.014305 (rank : 73)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

HRX_HUMAN
NC score	0.014272 (rank : 74)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	825	Shared Neighborhood Hits	24
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CS007_MOUSE
NC score	0.013458 (rank : 75)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	464	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

LRMP_HUMAN
NC score	0.013024 (rank : 76)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

TSH2_HUMAN
NC score	0.011938 (rank : 77)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	479	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

PDE4D_HUMAN
NC score	0.011784 (rank : 78)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PDE4D_MOUSE
NC score	0.011289 (rank : 79)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

TITIN_HUMAN
NC score	0.011069 (rank : 80)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	2923	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CLMN_HUMAN
NC score	0.011033 (rank : 81)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

MLL2_HUMAN
NC score	0.010878 (rank : 82)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	31
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PSMD2_MOUSE
NC score	0.010833 (rank : 83)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

PRKDC_MOUSE
NC score	0.010679 (rank : 84)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

PEPL_MOUSE
NC score	0.009857 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	1105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

ENPL_MOUSE
NC score	0.008516 (rank : 86)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

FLIP1_HUMAN
NC score	0.008275 (rank : 87)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	1405	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SPEG_MOUSE
NC score	0.008076 (rank : 88)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	1959	Shared Neighborhood Hits	29
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

E41L2_MOUSE
NC score	0.008027 (rank : 89)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	459	Shared Neighborhood Hits	28
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ACK1_HUMAN
NC score	0.007120 (rank : 90)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	1140	Shared Neighborhood Hits	21
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

PER2_MOUSE
NC score	0.006603 (rank : 91)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	325	Shared Neighborhood Hits	7
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

SH23A_HUMAN
NC score	0.006369 (rank : 92)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BRG2, Q9Y2X4	Gene names	SH2D3A, NSP1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3A (Novel SH2-containing protein 1).

ACK1_MOUSE
NC score	0.006186 (rank : 93)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	1080	Shared Neighborhood Hits	15
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

PEG3_HUMAN
NC score	0.005873 (rank : 94)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	800	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

CAC1C_HUMAN
NC score	0.005486 (rank : 95)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

ANR26_MOUSE
NC score	0.004840 (rank : 96)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	1554	Shared Neighborhood Hits	23
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

UACA_MOUSE
NC score	0.003793 (rank : 97)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

SLK_HUMAN
NC score	0.003606 (rank : 98)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	1775	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SPEG_HUMAN
NC score	0.003425 (rank : 99)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	1762	Shared Neighborhood Hits	23
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SLK_MOUSE
NC score	0.002811 (rank : 100)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	1798	Shared Neighborhood Hits	33
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).