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Network neighborhood for query Sequence : SIGIR_HUMAN

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SIGIR_HUMAN
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SIGIR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

SIGIR_MOUSE
θ value	0 (rank : 2)	NC score	0.980327 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	95	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

IRPL2_MOUSE
θ value	8.10077e-17 (rank : 3)	NC score	0.655076 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	195	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

IRPL1_HUMAN
θ value	8.95645e-16 (rank : 4)	NC score	0.650541 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	196	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL2_HUMAN
θ value	1.99529e-15 (rank : 5)	NC score	0.654756 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL1_MOUSE
θ value	5.8054e-15 (rank : 6)	NC score	0.641533 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	186	Shared Neighborhood Hits	33
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IL1AP_HUMAN
θ value	1.29331e-14 (rank : 7)	NC score	0.709929 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NPH3, O14915, Q86WJ7	Gene names	IL1RAP
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

IL1AP_MOUSE
θ value	4.91457e-14 (rank : 8)	NC score	0.703533 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q61730, Q8VCB9	Gene names	Il1rap
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

IL18R_MOUSE
θ value	2.69671e-12 (rank : 9)	NC score	0.705890 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q61098	Gene names	Il18r1
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp).

ILRL1_HUMAN
θ value	6.00763e-12 (rank : 10)	NC score	0.654444 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	167	Shared Neighborhood Hits	40
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

IL1R1_HUMAN
θ value	1.74796e-11 (rank : 11)	NC score	0.617441 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IL18R_HUMAN
θ value	2.28291e-11 (rank : 12)	NC score	0.700687 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q13478	Gene names	IL18R1, IL1RRP
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp) (CDw218a antigen).

ILRL1_MOUSE
θ value	1.133e-10 (rank : 13)	NC score	0.656663 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	172	Shared Neighborhood Hits	41
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

IL1R1_MOUSE
θ value	7.34386e-10 (rank : 14)	NC score	0.611064 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	142	Shared Neighborhood Hits	29
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

ILRL2_MOUSE
θ value	2.79066e-09 (rank : 15)	NC score	0.603289 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

ILRL2_HUMAN
θ value	3.64472e-09 (rank : 16)	NC score	0.617427 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	112	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

I18RA_HUMAN
θ value	1.09739e-05 (rank : 17)	NC score	0.623037 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	O95256, Q53TT4, Q53TU5	Gene names	IL18RAP
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7) (CDw218b antigen).

I18RA_MOUSE
θ value	5.44631e-05 (rank : 18)	NC score	0.621036 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	93	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z2B1	Gene names	Il18rap
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7).

TLR2_HUMAN
θ value	7.1131e-05 (rank : 19)	NC score	0.253643 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	290	Shared Neighborhood Hits	30
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

TLR2_MOUSE
θ value	9.29e-05 (rank : 20)	NC score	0.249961 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QUN7, Q3U400, Q9DBC4	Gene names	Tlr2
Domain Architecture
Description	Toll-like receptor 2 precursor (CD282 antigen).

MYD88_MOUSE
θ value	0.000121331 (rank : 21)	NC score	0.368755 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	P22366, O35916	Gene names	Myd88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

TLR13_MOUSE
θ value	0.00020696 (rank : 22)	NC score	0.172661 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	34
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

MYD88_HUMAN
θ value	0.000270298 (rank : 23)	NC score	0.381785 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	Q99836, P78397	Gene names	MYD88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

TLR4_HUMAN
θ value	0.00509761 (rank : 24)	NC score	0.194198 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	31
SwissProt Accessions	O00206, Q9UK78, Q9UM57	Gene names	TLR4
Domain Architecture
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

TLR11_MOUSE
θ value	0.0330416 (rank : 25)	NC score	0.126612 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	23
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

TLR1_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.257880 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	280	Shared Neighborhood Hits	31
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TLR4_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.179672 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

TLR6_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.238461 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2C9	Gene names	TLR6
Domain Architecture
Description	Toll-like receptor 6 precursor.

PUNC_MOUSE
θ value	0.0563607 (rank : 29)	NC score	0.066942 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	501	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TLR5_HUMAN
θ value	0.0563607 (rank : 30)	NC score	0.130648 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	27
SwissProt Accessions	O60602, O15456	Gene names	TLR5, TIL3
Domain Architecture
Description	Toll-like receptor 5 precursor (Toll/interleukin-1 receptor-like protein 3).

TLR6_MOUSE
θ value	0.0736092 (rank : 31)	NC score	0.219998 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPW9, Q9WTQ4	Gene names	Tlr6
Domain Architecture
Description	Toll-like receptor 6 precursor.

TLR12_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.172210 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	Q6QNU9	Gene names	Tlr12
Domain Architecture	No domain graphic available
Description	Toll-like receptor 12 precursor.

OBSCN_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.043859 (rank : 90)
Query Neighborhood Hits	53	Target Neighborhood Hits	1931	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TLR5_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.118414 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	287	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLF7	Gene names	Tlr5
Domain Architecture
Description	Toll-like receptor 5 precursor.

TLR1_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.216994 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	286	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPQ1, Q9EPW5	Gene names	Tlr1
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

HMCN1_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.066998 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	983	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LU_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.054607 (rank : 76)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

PUNC_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.063875 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	449	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

MYCL2_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.029775 (rank : 92)
Query Neighborhood Hits	53	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

KIRR2_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.076990 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	326	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

SN_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.036719 (rank : 91)
Query Neighborhood Hits	53	Target Neighborhood Hits	416	Shared Neighborhood Hits	16
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

TITIN_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.050781 (rank : 88)
Query Neighborhood Hits	53	Target Neighborhood Hits	2923	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TLR10_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.190262 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXR5, Q5FWG4, Q6UXL3	Gene names	TLR10
Domain Architecture
Description	Toll-like receptor 10 precursor.

LX15B_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.013314 (rank : 94)
Query Neighborhood Hits	53	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

ROBO3_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.069212 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	524	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

CXAR_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.026509 (rank : 93)
Query Neighborhood Hits	53	Target Neighborhood Hits	250	Shared Neighborhood Hits	11
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

CXB5_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.007659 (rank : 97)
Query Neighborhood Hits	53	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	O95377, Q9UPA3	Gene names	GJB5
Domain Architecture
Description	Gap junction beta-5 protein (Connexin-31.1) (Cx31.1).

DCC_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.056595 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCAM_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.058780 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	524	Shared Neighborhood Hits	27
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.052329 (rank : 82)
Query Neighborhood Hits	53	Target Neighborhood Hits	589	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

PGH1_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.009779 (rank : 96)
Query Neighborhood Hits	53	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

ELK1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.010016 (rank : 95)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

TIRAP_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.152746 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q99JY1, Q91ZW0	Gene names	Tirap, Mal
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

CD180_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.053290 (rank : 80)
Query Neighborhood Hits	53	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q99467	Gene names	CD180, LY64, RP105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 64) (Radioprotective 105 kDa protein).

CDON_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.057051 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	410	Shared Neighborhood Hits	24
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CNTN3_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.050471 (rank : 89)
Query Neighborhood Hits	53	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN4_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.052229 (rank : 83)
Query Neighborhood Hits	53	Target Neighborhood Hits	445	Shared Neighborhood Hits	26
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN6_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.051624 (rank : 85)
Query Neighborhood Hits	53	Target Neighborhood Hits	429	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

DCC_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.050820 (rank : 87)
Query Neighborhood Hits	53	Target Neighborhood Hits	583	Shared Neighborhood Hits	24
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

FGRL1_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.053803 (rank : 78)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.058815 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

IL1R2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.390473 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	25
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.404985 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

JAM1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.061889 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	294	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

LAG3_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.051942 (rank : 84)
Query Neighborhood Hits	53	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LRIG1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.087942 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	654	Shared Neighborhood Hits	42
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.077210 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	627	Shared Neighborhood Hits	41
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.066909 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	595	Shared Neighborhood Hits	37
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.063787 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	586	Shared Neighborhood Hits	36
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.064753 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	601	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.067007 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	611	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MYOTI_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.051038 (rank : 86)
Query Neighborhood Hits	53	Target Neighborhood Hits	292	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

NCA11_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.055876 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA11_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.055418 (rank : 73)
Query Neighborhood Hits	53	Target Neighborhood Hits	661	Shared Neighborhood Hits	26
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.056583 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	437	Shared Neighborhood Hits	28
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA12_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.057666 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	399	Shared Neighborhood Hits	26
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

NCAM2_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.053140 (rank : 81)
Query Neighborhood Hits	53	Target Neighborhood Hits	441	Shared Neighborhood Hits	24
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NCAM2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.063731 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	472	Shared Neighborhood Hits	25
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NRCAM_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.058722 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	439	Shared Neighborhood Hits	27
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.057675 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	432	Shared Neighborhood Hits	25
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NTRI_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.054771 (rank : 75)
Query Neighborhood Hits	53	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

OBSL1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.074104 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ROBO1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.054345 (rank : 77)
Query Neighborhood Hits	53	Target Neighborhood Hits	529	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

ROBO1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.054896 (rank : 74)
Query Neighborhood Hits	53	Target Neighborhood Hits	559	Shared Neighborhood Hits	25
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.055664 (rank : 71)
Query Neighborhood Hits	53	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.055453 (rank : 72)
Query Neighborhood Hits	53	Target Neighborhood Hits	504	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO3_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.057743 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	570	Shared Neighborhood Hits	24
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

TIRAP_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.123859 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	P58753, Q8N5E5	Gene names	TIRAP, MAL
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

TLR3_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.083907 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TLR3_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.085625 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TLR7_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.111561 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

TLR7_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.117526 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	P58681, Q923I1	Gene names	Tlr7
Domain Architecture
Description	Toll-like receptor 7 precursor.

TLR8_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.107082 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NR97, Q6UXL6, Q9NYG9	Gene names	TLR8
Domain Architecture
Description	Toll-like receptor 8 precursor.

TLR8_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.112116 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	297	Shared Neighborhood Hits	26
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

TLR9_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.090068 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

TLR9_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.088929 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

TMIGD_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.053319 (rank : 79)
Query Neighborhood Hits	53	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

Hits sorted by NC score

SIGIR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q6IA17, Q3KQY2, Q6UXI3, Q9H733	Gene names	SIGIRR
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

SIGIR_MOUSE
NC score	0.980327 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	95	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

IL1AP_HUMAN
NC score	0.709929 (rank : 3)	θ value	1.29331e-14 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NPH3, O14915, Q86WJ7	Gene names	IL1RAP
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

IL18R_MOUSE
NC score	0.705890 (rank : 4)	θ value	2.69671e-12 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q61098	Gene names	Il18r1
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp).

IL1AP_MOUSE
NC score	0.703533 (rank : 5)	θ value	4.91457e-14 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	94	Shared Neighborhood Hits	38
SwissProt Accessions	Q61730, Q8VCB9	Gene names	Il1rap
Domain Architecture
Description	Interleukin-1 receptor accessory protein precursor (IL-1 receptor accessory protein) (IL-1RAcP).

IL18R_HUMAN
NC score	0.700687 (rank : 6)	θ value	2.28291e-11 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q13478	Gene names	IL18R1, IL1RRP
Domain Architecture
Description	Interleukin-18 receptor 1 precursor (IL1 receptor-related protein) (IL-1Rrp) (CDw218a antigen).

ILRL1_MOUSE
NC score	0.656663 (rank : 7)	θ value	1.133e-10 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	172	Shared Neighborhood Hits	41
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

IRPL2_MOUSE
NC score	0.655076 (rank : 8)	θ value	8.10077e-17 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	195	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

IRPL2_HUMAN
NC score	0.654756 (rank : 9)	θ value	1.99529e-15 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

ILRL1_HUMAN
NC score	0.654444 (rank : 10)	θ value	6.00763e-12 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	167	Shared Neighborhood Hits	40
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

IRPL1_HUMAN
NC score	0.650541 (rank : 11)	θ value	8.95645e-16 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	196	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
NC score	0.641533 (rank : 12)	θ value	5.8054e-15 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	186	Shared Neighborhood Hits	33
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

I18RA_HUMAN
NC score	0.623037 (rank : 13)	θ value	1.09739e-05 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	O95256, Q53TT4, Q53TU5	Gene names	IL18RAP
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7) (CDw218b antigen).

I18RA_MOUSE
NC score	0.621036 (rank : 14)	θ value	5.44631e-05 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	93	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z2B1	Gene names	Il18rap
Domain Architecture	No domain graphic available
Description	Interleukin-18 receptor accessory protein precursor (IL-18 receptor accessory protein) (IL-18RAcP) (Interleukin-18 receptor accessory protein-like) (IL-18Rbeta) (IL-1R accessory protein-like) (IL-1RAcPL) (Accessory protein-like) (AcPL) (IL-1R7).

IL1R1_HUMAN
NC score	0.617441 (rank : 15)	θ value	1.74796e-11 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

ILRL2_HUMAN
NC score	0.617427 (rank : 16)	θ value	3.64472e-09 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	112	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

IL1R1_MOUSE
NC score	0.611064 (rank : 17)	θ value	7.34386e-10 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	142	Shared Neighborhood Hits	29
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

ILRL2_MOUSE
NC score	0.603289 (rank : 18)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

IL1R2_MOUSE
NC score	0.404985 (rank : 19)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL1R2_HUMAN
NC score	0.390473 (rank : 20)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	25
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

MYD88_HUMAN
NC score	0.381785 (rank : 21)	θ value	0.000270298 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	Q99836, P78397	Gene names	MYD88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

MYD88_MOUSE
NC score	0.368755 (rank : 22)	θ value	0.000121331 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	P22366, O35916	Gene names	Myd88
Domain Architecture
Description	Myeloid differentiation primary response protein MyD88.

TLR1_HUMAN
NC score	0.257880 (rank : 23)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	280	Shared Neighborhood Hits	31
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TLR2_HUMAN
NC score	0.253643 (rank : 24)	θ value	7.1131e-05 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	290	Shared Neighborhood Hits	30
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

TLR2_MOUSE
NC score	0.249961 (rank : 25)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QUN7, Q3U400, Q9DBC4	Gene names	Tlr2
Domain Architecture
Description	Toll-like receptor 2 precursor (CD282 antigen).

TLR6_HUMAN
NC score	0.238461 (rank : 26)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2C9	Gene names	TLR6
Domain Architecture
Description	Toll-like receptor 6 precursor.

TLR6_MOUSE
NC score	0.219998 (rank : 27)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPW9, Q9WTQ4	Gene names	Tlr6
Domain Architecture
Description	Toll-like receptor 6 precursor.

TLR1_MOUSE
NC score	0.216994 (rank : 28)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	286	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EPQ1, Q9EPW5	Gene names	Tlr1
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

TLR4_HUMAN
NC score	0.194198 (rank : 29)	θ value	0.00509761 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	31
SwissProt Accessions	O00206, Q9UK78, Q9UM57	Gene names	TLR4
Domain Architecture
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

TLR10_HUMAN
NC score	0.190262 (rank : 30)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXR5, Q5FWG4, Q6UXL3	Gene names	TLR10
Domain Architecture
Description	Toll-like receptor 10 precursor.

TLR4_MOUSE
NC score	0.179672 (rank : 31)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QUK6, Q9D691, Q9QZF5, Q9Z203	Gene names	Tlr4, Lps
Domain Architecture
Description	Toll-like receptor 4 precursor (CD284 antigen).

TLR13_MOUSE
NC score	0.172661 (rank : 32)	θ value	0.00020696 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	34
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

TLR12_MOUSE
NC score	0.172210 (rank : 33)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	27
SwissProt Accessions	Q6QNU9	Gene names	Tlr12
Domain Architecture	No domain graphic available
Description	Toll-like receptor 12 precursor.

TIRAP_MOUSE
NC score	0.152746 (rank : 34)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q99JY1, Q91ZW0	Gene names	Tirap, Mal
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

TLR5_HUMAN
NC score	0.130648 (rank : 35)	θ value	0.0563607 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	27
SwissProt Accessions	O60602, O15456	Gene names	TLR5, TIL3
Domain Architecture
Description	Toll-like receptor 5 precursor (Toll/interleukin-1 receptor-like protein 3).

TLR11_MOUSE
NC score	0.126612 (rank : 36)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	23
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

TIRAP_HUMAN
NC score	0.123859 (rank : 37)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	53	Target Neighborhood Hits	33	Shared Neighborhood Hits	22
SwissProt Accessions	P58753, Q8N5E5	Gene names	TIRAP, MAL
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

TLR5_MOUSE
NC score	0.118414 (rank : 38)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	287	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLF7	Gene names	Tlr5
Domain Architecture
Description	Toll-like receptor 5 precursor.

TLR7_MOUSE
NC score	0.117526 (rank : 39)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	53	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	P58681, Q923I1	Gene names	Tlr7
Domain Architecture
Description	Toll-like receptor 7 precursor.

TLR8_MOUSE
NC score	0.112116 (rank : 40)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	53	Target Neighborhood Hits	297	Shared Neighborhood Hits	26
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

TLR7_HUMAN
NC score	0.111561 (rank : 41)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	53	Target Neighborhood Hits	312	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

TLR8_HUMAN
NC score	0.107082 (rank : 42)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NR97, Q6UXL6, Q9NYG9	Gene names	TLR8
Domain Architecture
Description	Toll-like receptor 8 precursor.

TLR9_HUMAN
NC score	0.090068 (rank : 43)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

TLR9_MOUSE
NC score	0.088929 (rank : 44)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	53	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRIG1_HUMAN
NC score	0.087942 (rank : 45)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	654	Shared Neighborhood Hits	42
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

TLR3_MOUSE
NC score	0.085625 (rank : 46)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	Q99MB1, Q91ZM4	Gene names	Tlr3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

TLR3_HUMAN
NC score	0.083907 (rank : 47)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	53	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

LRIG1_MOUSE
NC score	0.077210 (rank : 48)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	627	Shared Neighborhood Hits	41
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

KIRR2_MOUSE
NC score	0.076990 (rank : 49)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	326	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

OBSL1_HUMAN
NC score	0.074104 (rank : 50)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	53	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ROBO3_MOUSE
NC score	0.069212 (rank : 51)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	524	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

LRIG3_MOUSE
NC score	0.067007 (rank : 52)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	53	Target Neighborhood Hits	611	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

HMCN1_HUMAN
NC score	0.066998 (rank : 53)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	983	Shared Neighborhood Hits	31
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

PUNC_MOUSE
NC score	0.066942 (rank : 54)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	501	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

LRIG2_HUMAN
NC score	0.066909 (rank : 55)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	595	Shared Neighborhood Hits	37
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG3_HUMAN
NC score	0.064753 (rank : 56)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	601	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

PUNC_HUMAN
NC score	0.063875 (rank : 57)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	449	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

LRIG2_MOUSE
NC score	0.063787 (rank : 58)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	586	Shared Neighborhood Hits	36
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

NCAM2_MOUSE
NC score	0.063731 (rank : 59)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	53	Target Neighborhood Hits	472	Shared Neighborhood Hits	25
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

JAM1_HUMAN
NC score	0.061889 (rank : 60)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	294	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

FGRL1_MOUSE
NC score	0.058815 (rank : 61)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

DSCAM_HUMAN
NC score	0.058780 (rank : 62)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	524	Shared Neighborhood Hits	27
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

NRCAM_HUMAN
NC score	0.058722 (rank : 63)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	53	Target Neighborhood Hits	439	Shared Neighborhood Hits	27
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

ROBO3_HUMAN
NC score	0.057743 (rank : 64)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	53	Target Neighborhood Hits	570	Shared Neighborhood Hits	24
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

NRCAM_MOUSE
NC score	0.057675 (rank : 65)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	53	Target Neighborhood Hits	432	Shared Neighborhood Hits	25
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NCA12_MOUSE
NC score	0.057666 (rank : 66)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	53	Target Neighborhood Hits	399	Shared Neighborhood Hits	26
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

CDON_MOUSE
NC score	0.057051 (rank : 67)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	410	Shared Neighborhood Hits	24
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

DCC_MOUSE
NC score	0.056595 (rank : 68)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

NCA12_HUMAN
NC score	0.056583 (rank : 69)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	53	Target Neighborhood Hits	437	Shared Neighborhood Hits	28
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA11_HUMAN
NC score	0.055876 (rank : 70)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	53	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

ROBO2_HUMAN
NC score	0.055664 (rank : 71)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	53	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
NC score	0.055453 (rank : 72)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	53	Target Neighborhood Hits	504	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

NCA11_MOUSE
NC score	0.055418 (rank : 73)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	53	Target Neighborhood Hits	661	Shared Neighborhood Hits	26
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

ROBO1_MOUSE
NC score	0.054896 (rank : 74)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	53	Target Neighborhood Hits	559	Shared Neighborhood Hits	25
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

NTRI_HUMAN
NC score	0.054771 (rank : 75)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	53	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

LU_HUMAN
NC score	0.054607 (rank : 76)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

ROBO1_HUMAN
NC score	0.054345 (rank : 77)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	53	Target Neighborhood Hits	529	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

FGRL1_HUMAN
NC score	0.053803 (rank : 78)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

TMIGD_HUMAN
NC score	0.053319 (rank : 79)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	53	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

CD180_HUMAN
NC score	0.053290 (rank : 80)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	279	Shared Neighborhood Hits	14
SwissProt Accessions	Q99467	Gene names	CD180, LY64, RP105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 64) (Radioprotective 105 kDa protein).

NCAM2_HUMAN
NC score	0.053140 (rank : 81)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	53	Target Neighborhood Hits	441	Shared Neighborhood Hits	24
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

DSCL1_HUMAN
NC score	0.052329 (rank : 82)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	589	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

CNTN4_MOUSE
NC score	0.052229 (rank : 83)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	445	Shared Neighborhood Hits	26
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

LAG3_MOUSE
NC score	0.051942 (rank : 84)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

CNTN6_MOUSE
NC score	0.051624 (rank : 85)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	429	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

MYOTI_HUMAN
NC score	0.051038 (rank : 86)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	53	Target Neighborhood Hits	292	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

DCC_HUMAN
NC score	0.050820 (rank : 87)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	583	Shared Neighborhood Hits	24
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

TITIN_HUMAN
NC score	0.050781 (rank : 88)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	2923	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CNTN3_HUMAN
NC score	0.050471 (rank : 89)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

OBSCN_HUMAN
NC score	0.043859 (rank : 90)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	1931	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SN_MOUSE
NC score	0.036719 (rank : 91)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	416	Shared Neighborhood Hits	16
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

MYCL2_HUMAN
NC score	0.029775 (rank : 92)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

CXAR_MOUSE
NC score	0.026509 (rank : 93)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	250	Shared Neighborhood Hits	11
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

LX15B_HUMAN
NC score	0.013314 (rank : 94)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

ELK1_MOUSE
NC score	0.010016 (rank : 95)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

PGH1_MOUSE
NC score	0.009779 (rank : 96)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

CXB5_HUMAN
NC score	0.007659 (rank : 97)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	O95377, Q9UPA3	Gene names	GJB5
Domain Architecture
Description	Gap junction beta-5 protein (Connexin-31.1) (Cx31.1).