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Network neighborhood for query Sequence : MBIP1_MOUSE

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MBIP1_MOUSE
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MBIP1_MOUSE
θ value	7.49059e-172 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

MBIP1_HUMAN
θ value	5.96274e-153 (rank : 2)	NC score	0.983064 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NS73, Q86TZ2, Q96AS5, Q9BS93, Q9NZE1	Gene names	MBIP
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

RB6I2_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.031388 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	1584	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RFA1_HUMAN
θ value	0.365318 (rank : 4)	NC score	0.072040 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).

RB6I2_MOUSE
θ value	0.47712 (rank : 5)	NC score	0.031118 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	1433	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

NFKB1_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.019956 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

BPAEA_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.026832 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	1480	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HOOK1_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.027897 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	910	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

TBCD4_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.028442 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

CING_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.019051 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	1432	Shared Neighborhood Hits	11
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

HOOK1_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.027070 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	942	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

BPAEA_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.021126 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	1369	Shared Neighborhood Hits	10
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

NDUA1_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.063339 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	O35683	Gene names	Ndufa1
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase MWFE subunit) (Complex I-MWFE) (CI-MWFE).

ROCK2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.008116 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	2072	Shared Neighborhood Hits	11
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TCF8_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.003619 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	1057	Shared Neighborhood Hits	5
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

RM40_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.026765 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2Q5, Q9CS52	Gene names	Mrpl40, Nlvcf
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L40, mitochondrial precursor (L40mt) (MRP-40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog).

TITIN_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.004971 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	2923	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FLNA_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.014883 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.014874 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

ST5_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.008937 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

Hits sorted by NC score

MBIP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	7.49059e-172 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q99LQ1, Q3TBM3	Gene names	Mbip
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

MBIP1_HUMAN
NC score	0.983064 (rank : 2)	θ value	5.96274e-153 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NS73, Q86TZ2, Q96AS5, Q9BS93, Q9NZE1	Gene names	MBIP
Domain Architecture	No domain graphic available
Description	MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein).

RFA1_HUMAN
NC score	0.072040 (rank : 3)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P27694, Q59ES9	Gene names	RPA1, REPA1, RPA70
Domain Architecture
Description	Replication protein A 70 kDa DNA-binding subunit (RP-A) (RF-A) (Replication factor-A protein 1) (Single-stranded DNA-binding protein) (p70).

NDUA1_MOUSE
NC score	0.063339 (rank : 4)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	O35683	Gene names	Ndufa1
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase MWFE subunit) (Complex I-MWFE) (CI-MWFE).

RB6I2_HUMAN
NC score	0.031388 (rank : 5)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	1584	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
NC score	0.031118 (rank : 6)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	1433	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

TBCD4_HUMAN
NC score	0.028442 (rank : 7)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

HOOK1_MOUSE
NC score	0.027897 (rank : 8)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	910	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK1_HUMAN
NC score	0.027070 (rank : 9)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	942	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

BPAEA_MOUSE
NC score	0.026832 (rank : 10)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	1480	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RM40_MOUSE
NC score	0.026765 (rank : 11)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2Q5, Q9CS52	Gene names	Mrpl40, Nlvcf
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L40, mitochondrial precursor (L40mt) (MRP-40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog).

BPAEA_HUMAN
NC score	0.021126 (rank : 12)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	1369	Shared Neighborhood Hits	10
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

NFKB1_HUMAN
NC score	0.019956 (rank : 13)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

CING_MOUSE
NC score	0.019051 (rank : 14)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	1432	Shared Neighborhood Hits	11
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

FLNA_HUMAN
NC score	0.014883 (rank : 15)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
NC score	0.014874 (rank : 16)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	142	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

ST5_MOUSE
NC score	0.008937 (rank : 17)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

ROCK2_MOUSE
NC score	0.008116 (rank : 18)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	2072	Shared Neighborhood Hits	11
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TITIN_HUMAN
NC score	0.004971 (rank : 19)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	2923	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TCF8_HUMAN
NC score	0.003619 (rank : 20)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	1057	Shared Neighborhood Hits	5
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).