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Network neighborhood for query Sequence : PDE1C_HUMAN

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PDE1C_HUMAN
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDE1A_HUMAN
θ value	0 (rank : 1)	NC score	0.990753 (rank : 4)
Query Neighborhood Hits	134	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	P54750, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2, Q9C0L3, Q9C0L4, Q9UFX3	Gene names	PDE1A
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE) (hCam-1).

PDE1A_MOUSE
θ value	0 (rank : 2)	NC score	0.990825 (rank : 3)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	Q61481, O35388	Gene names	Pde1a
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).

PDE1C_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	134	Target Neighborhood Hits	134	Shared Neighborhood Hits	134
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

PDE1C_MOUSE
θ value	0 (rank : 4)	NC score	0.993821 (rank : 2)
Query Neighborhood Hits	134	Target Neighborhood Hits	161	Shared Neighborhood Hits	89
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PDE1B_HUMAN
θ value	9.13544e-178 (rank : 5)	NC score	0.988485 (rank : 6)
Query Neighborhood Hits	134	Target Neighborhood Hits	50	Shared Neighborhood Hits	39
SwissProt Accessions	Q01064, Q92825	Gene names	PDE1B, PDE1B1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE1B_MOUSE
θ value	7.7336e-177 (rank : 6)	NC score	0.988639 (rank : 5)
Query Neighborhood Hits	134	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q01065, O35384	Gene names	Pde1b, Pde1b1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE4D_HUMAN
θ value	7.47731e-63 (rank : 7)	NC score	0.923249 (rank : 12)
Query Neighborhood Hits	134	Target Neighborhood Hits	122	Shared Neighborhood Hits	40
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PDE4D_MOUSE
θ value	7.47731e-63 (rank : 8)	NC score	0.923936 (rank : 10)
Query Neighborhood Hits	134	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

PDE4A_MOUSE
θ value	8.26713e-62 (rank : 9)	NC score	0.923420 (rank : 11)
Query Neighborhood Hits	134	Target Neighborhood Hits	66	Shared Neighborhood Hits	39
SwissProt Accessions	O89084, Q8R078, Q9JHQ4, Q9QX48, Q9QX49, Q9QXI8	Gene names	Pde4a
Domain Architecture
Description	cAMP-dependent 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17).

PDE4A_HUMAN
θ value	1.41016e-61 (rank : 10)	NC score	0.922757 (rank : 13)
Query Neighborhood Hits	134	Target Neighborhood Hits	73	Shared Neighborhood Hits	38
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PDE4C_MOUSE
θ value	2.40537e-61 (rank : 11)	NC score	0.928241 (rank : 7)
Query Neighborhood Hits	134	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

PDE4B_HUMAN
θ value	2.03627e-60 (rank : 12)	NC score	0.924173 (rank : 9)
Query Neighborhood Hits	134	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q07343, O15443	Gene names	PDE4B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32).

PDE4C_HUMAN
θ value	4.53632e-60 (rank : 13)	NC score	0.925765 (rank : 8)
Query Neighborhood Hits	134	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q08493, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6	Gene names	PDE4C
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17) (DPDE1) (PDE21).

PDE3A_MOUSE
θ value	1.67352e-46 (rank : 14)	NC score	0.902067 (rank : 25)
Query Neighborhood Hits	134	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3A_HUMAN
θ value	2.85459e-46 (rank : 15)	NC score	0.903226 (rank : 22)
Query Neighborhood Hits	134	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3B_HUMAN
θ value	5.38352e-45 (rank : 16)	NC score	0.912426 (rank : 18)
Query Neighborhood Hits	134	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

PDE8A_HUMAN
θ value	5.38352e-45 (rank : 17)	NC score	0.905375 (rank : 20)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O60658, Q969I1, Q96PC9, Q96PD0, Q96PD1, Q9UMB7	Gene names	PDE8A
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17).

PDE7A_HUMAN
θ value	3.85808e-43 (rank : 18)	NC score	0.919892 (rank : 16)
Query Neighborhood Hits	134	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q13946, O15380	Gene names	PDE7A
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (HCP1) (TM22).

PDE8A_MOUSE
θ value	6.58091e-43 (rank : 19)	NC score	0.902501 (rank : 23)
Query Neighborhood Hits	134	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

PDE7A_MOUSE
θ value	3.26607e-42 (rank : 20)	NC score	0.919987 (rank : 15)
Query Neighborhood Hits	134	Target Neighborhood Hits	39	Shared Neighborhood Hits	38
SwissProt Accessions	P70453, Q9ERB3	Gene names	Pde7a
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (P2A).

PDE7B_MOUSE
θ value	3.26607e-42 (rank : 21)	NC score	0.920064 (rank : 14)
Query Neighborhood Hits	134	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXQ1	Gene names	Pde7b
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE8B_HUMAN
θ value	7.27602e-42 (rank : 22)	NC score	0.902227 (rank : 24)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95263, Q86XK8, Q8IUJ7, Q8IUJ8, Q8IUJ9, Q8IUK0, Q8N3T2	Gene names	PDE8B
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (EC 3.1.4.17) (HSPDE8B).

PDE7B_HUMAN
θ value	1.2411e-41 (rank : 23)	NC score	0.919055 (rank : 17)
Query Neighborhood Hits	134	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP56	Gene names	PDE7B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE9A_MOUSE
θ value	2.26708e-35 (rank : 24)	NC score	0.907003 (rank : 19)
Query Neighborhood Hits	134	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE9A_HUMAN
θ value	6.59618e-35 (rank : 25)	NC score	0.903547 (rank : 21)
Query Neighborhood Hits	134	Target Neighborhood Hits	93	Shared Neighborhood Hits	38
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE2A_MOUSE
θ value	1.85889e-29 (rank : 26)	NC score	0.839797 (rank : 26)
Query Neighborhood Hits	134	Target Neighborhood Hits	49	Shared Neighborhood Hits	39
SwissProt Accessions	Q922S4, Q8K2U1	Gene names	Pde2a
Domain Architecture	No domain graphic available
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE2A_HUMAN
θ value	2.42779e-29 (rank : 27)	NC score	0.838994 (rank : 27)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	39
SwissProt Accessions	O00408	Gene names	PDE2A
Domain Architecture
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE11_MOUSE
θ value	2.96777e-27 (rank : 28)	NC score	0.817847 (rank : 28)
Query Neighborhood Hits	134	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	P0C1Q2	Gene names	Pde11a
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE11_HUMAN
θ value	3.87602e-27 (rank : 29)	NC score	0.817547 (rank : 29)
Query Neighborhood Hits	134	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCR9, Q53T16, Q96S76, Q9GZY7, Q9HB46, Q9NY45	Gene names	PDE11A
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE6A_HUMAN
θ value	5.06226e-27 (rank : 30)	NC score	0.785097 (rank : 35)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

PDE6C_HUMAN
θ value	2.51237e-26 (rank : 31)	NC score	0.789127 (rank : 34)
Query Neighborhood Hits	134	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6C_MOUSE
θ value	7.30988e-26 (rank : 32)	NC score	0.789742 (rank : 33)
Query Neighborhood Hits	134	Target Neighborhood Hits	45	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6A_MOUSE
θ value	1.24688e-25 (rank : 33)	NC score	0.780660 (rank : 36)
Query Neighborhood Hits	134	Target Neighborhood Hits	45	Shared Neighborhood Hits	38
SwissProt Accessions	P27664	Gene names	Pde6a, Mpa, Pdea
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha).

PDE5A_MOUSE
θ value	6.18819e-25 (rank : 34)	NC score	0.800267 (rank : 31)
Query Neighborhood Hits	134	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG03	Gene names	Pde5a, Pde5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE6B_HUMAN
θ value	6.18819e-25 (rank : 35)	NC score	0.780134 (rank : 37)
Query Neighborhood Hits	134	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	P35913, Q9BWH5	Gene names	PDE6B, PDEB
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase beta-subunit precursor (EC 3.1.4.35) (GMP-PDE beta).

PDE5A_HUMAN
θ value	8.08199e-25 (rank : 36)	NC score	0.795655 (rank : 32)
Query Neighborhood Hits	134	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	O76074, O75026, O75887, Q86UI0, Q86V66, Q9Y6Z6	Gene names	PDE5A, PDE5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE6B_MOUSE
θ value	3.07116e-24 (rank : 37)	NC score	0.777257 (rank : 38)
Query Neighborhood Hits	134	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	P23440	Gene names	Pde6b, Mpb, Pdeb, rd
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor (EC 3.1.4.35) (GMP-PDE beta).

PDE10_HUMAN
θ value	1.2077e-20 (rank : 38)	NC score	0.812873 (rank : 30)
Query Neighborhood Hits	134	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y233, Q9Y5T1	Gene names	PDE10A
Domain Architecture
Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17).

DSPP_HUMAN
θ value	0.000158464 (rank : 39)	NC score	0.063061 (rank : 41)
Query Neighborhood Hits	134	Target Neighborhood Hits	645	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RRBP1_MOUSE
θ value	0.00509761 (rank : 40)	NC score	0.029731 (rank : 60)
Query Neighborhood Hits	134	Target Neighborhood Hits	1650	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

LEO1_HUMAN
θ value	0.0148317 (rank : 41)	NC score	0.045756 (rank : 44)
Query Neighborhood Hits	134	Target Neighborhood Hits	958	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DSPP_MOUSE
θ value	0.0330416 (rank : 42)	NC score	0.063031 (rank : 42)
Query Neighborhood Hits	134	Target Neighborhood Hits	491	Shared Neighborhood Hits	35
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NSBP1_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.072884 (rank : 39)
Query Neighborhood Hits	134	Target Neighborhood Hits	251	Shared Neighborhood Hits	33
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

CYLC1_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.057266 (rank : 43)
Query Neighborhood Hits	134	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TEX15_HUMAN
θ value	0.0736092 (rank : 45)	NC score	0.045678 (rank : 45)
Query Neighborhood Hits	134	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

NPBL_MOUSE
θ value	0.0961366 (rank : 46)	NC score	0.040095 (rank : 52)
Query Neighborhood Hits	134	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NKTR_HUMAN
θ value	0.125558 (rank : 47)	NC score	0.040342 (rank : 51)
Query Neighborhood Hits	134	Target Neighborhood Hits	658	Shared Neighborhood Hits	54
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PPIG_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.033400 (rank : 55)
Query Neighborhood Hits	134	Target Neighborhood Hits	670	Shared Neighborhood Hits	50
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SRRM2_MOUSE
θ value	0.21417 (rank : 49)	NC score	0.028718 (rank : 64)
Query Neighborhood Hits	134	Target Neighborhood Hits	1470	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TITIN_HUMAN
θ value	0.279714 (rank : 50)	NC score	-0.001984 (rank : 132)
Query Neighborhood Hits	134	Target Neighborhood Hits	2923	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

HMMR_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.010780 (rank : 101)
Query Neighborhood Hits	134	Target Neighborhood Hits	1178	Shared Neighborhood Hits	32
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

PUM2_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.015322 (rank : 89)
Query Neighborhood Hits	134	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

RBBP6_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.042087 (rank : 48)
Query Neighborhood Hits	134	Target Neighborhood Hits	1135	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

B4GN4_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.014098 (rank : 93)
Query Neighborhood Hits	134	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

CYLC2_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.066462 (rank : 40)
Query Neighborhood Hits	134	Target Neighborhood Hits	223	Shared Neighborhood Hits	31
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

IWS1_MOUSE
θ value	0.62314 (rank : 56)	NC score	0.032939 (rank : 57)
Query Neighborhood Hits	134	Target Neighborhood Hits	1258	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SFR12_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.043504 (rank : 47)
Query Neighborhood Hits	134	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SRRM2_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.029414 (rank : 61)
Query Neighborhood Hits	134	Target Neighborhood Hits	1296	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

UBP8_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.010900 (rank : 98)
Query Neighborhood Hits	134	Target Neighborhood Hits	751	Shared Neighborhood Hits	41
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ARS2_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.041908 (rank : 49)
Query Neighborhood Hits	134	Target Neighborhood Hits	186	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

RNPS1_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.028824 (rank : 62)
Query Neighborhood Hits	134	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.028824 (rank : 63)
Query Neighborhood Hits	134	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

ZN638_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.017851 (rank : 84)
Query Neighborhood Hits	134	Target Neighborhood Hits	343	Shared Neighborhood Hits	21
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

CEBPG_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.027599 (rank : 66)
Query Neighborhood Hits	134	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

TCAL5_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.024514 (rank : 71)
Query Neighborhood Hits	134	Target Neighborhood Hits	806	Shared Neighborhood Hits	49
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TAF5_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.004439 (rank : 119)
Query Neighborhood Hits	134	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
θ value	1.38821 (rank : 67)	NC score	0.004461 (rank : 117)
Query Neighborhood Hits	134	Target Neighborhood Hits	366	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

CEBPG_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.024537 (rank : 70)
Query Neighborhood Hits	134	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P53568	Gene names	Cebpg
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-binding protein) (GPE1-BP).

GPTC8_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.041238 (rank : 50)
Query Neighborhood Hits	134	Target Neighborhood Hits	366	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IF4B_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.021964 (rank : 77)
Query Neighborhood Hits	134	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

NCKX1_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.019932 (rank : 82)
Query Neighborhood Hits	134	Target Neighborhood Hits	223	Shared Neighborhood Hits	20
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NIPBL_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.037229 (rank : 53)
Query Neighborhood Hits	134	Target Neighborhood Hits	1311	Shared Neighborhood Hits	63
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SH3BG_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.017630 (rank : 85)
Query Neighborhood Hits	134	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WUZ7	Gene names	Sh3bgr
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein).

ARS2_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.036132 (rank : 54)
Query Neighborhood Hits	134	Target Neighborhood Hits	212	Shared Neighborhood Hits	26
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

H14_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.016779 (rank : 87)
Query Neighborhood Hits	134	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	P43274	Gene names	Hist1h1e, H1f4
Domain Architecture
Description	Histone H1.4 (H1 VAR.2) (H1e).

LRRF1_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.019268 (rank : 83)
Query Neighborhood Hits	134	Target Neighborhood Hits	625	Shared Neighborhood Hits	29
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

NKTR_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.024890 (rank : 69)
Query Neighborhood Hits	134	Target Neighborhood Hits	417	Shared Neighborhood Hits	42
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

OXR1_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.024455 (rank : 72)
Query Neighborhood Hits	134	Target Neighborhood Hits	516	Shared Neighborhood Hits	33
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PHF2_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.006716 (rank : 110)
Query Neighborhood Hits	134	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PLEC1_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.002954 (rank : 124)
Query Neighborhood Hits	134	Target Neighborhood Hits	1326	Shared Neighborhood Hits	25
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RABE1_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.008539 (rank : 105)
Query Neighborhood Hits	134	Target Neighborhood Hits	1105	Shared Neighborhood Hits	30
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SEMG2_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.027121 (rank : 67)
Query Neighborhood Hits	134	Target Neighborhood Hits	251	Shared Neighborhood Hits	24
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

TRDN_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.022285 (rank : 75)
Query Neighborhood Hits	134	Target Neighborhood Hits	542	Shared Neighborhood Hits	33
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

U2AFM_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.014742 (rank : 91)
Query Neighborhood Hits	134	Target Neighborhood Hits	577	Shared Neighborhood Hits	28
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

AFF4_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.021669 (rank : 78)
Query Neighborhood Hits	134	Target Neighborhood Hits	581	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AP3B1_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.017132 (rank : 86)
Query Neighborhood Hits	134	Target Neighborhood Hits	283	Shared Neighborhood Hits	28
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ICAL_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.021509 (rank : 79)
Query Neighborhood Hits	134	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

LEO1_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.045374 (rank : 46)
Query Neighborhood Hits	134	Target Neighborhood Hits	946	Shared Neighborhood Hits	57
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PTPRG_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.006252 (rank : 112)
Query Neighborhood Hits	134	Target Neighborhood Hits	231	Shared Neighborhood Hits	13
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

ARAF_HUMAN
θ value	4.03905 (rank : 90)	NC score	-0.004178 (rank : 133)
Query Neighborhood Hits	134	Target Neighborhood Hits	924	Shared Neighborhood Hits	11
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

BMP2K_HUMAN
θ value	4.03905 (rank : 91)	NC score	-0.001222 (rank : 131)
Query Neighborhood Hits	134	Target Neighborhood Hits	867	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

C8AP2_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.023312 (rank : 73)
Query Neighborhood Hits	134	Target Neighborhood Hits	548	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

H14_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.015292 (rank : 90)
Query Neighborhood Hits	134	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

MOES_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.005452 (rank : 115)
Query Neighborhood Hits	134	Target Neighborhood Hits	892	Shared Neighborhood Hits	21
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYO5A_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.003052 (rank : 122)
Query Neighborhood Hits	134	Target Neighborhood Hits	1117	Shared Neighborhood Hits	27
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

ATX2_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.007817 (rank : 108)
Query Neighborhood Hits	134	Target Neighborhood Hits	375	Shared Neighborhood Hits	12
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

FGD3_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.003835 (rank : 121)
Query Neighborhood Hits	134	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

H13_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.014630 (rank : 92)
Query Neighborhood Hits	134	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

HTSF1_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.025113 (rank : 68)
Query Neighborhood Hits	134	Target Neighborhood Hits	425	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

IF2M_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.010868 (rank : 100)
Query Neighborhood Hits	134	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

IF2P_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.020187 (rank : 81)
Query Neighborhood Hits	134	Target Neighborhood Hits	889	Shared Neighborhood Hits	43
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

KIF14_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.001815 (rank : 128)
Query Neighborhood Hits	134	Target Neighborhood Hits	732	Shared Neighborhood Hits	22
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

NPAS3_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.007677 (rank : 109)
Query Neighborhood Hits	134	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

SEMG1_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.020941 (rank : 80)
Query Neighborhood Hits	134	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

SFR15_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.013623 (rank : 94)
Query Neighborhood Hits	134	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

UT14C_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.008474 (rank : 106)
Query Neighborhood Hits	134	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

ADA30_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.002760 (rank : 125)
Query Neighborhood Hits	134	Target Neighborhood Hits	391	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

BAZ1B_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.010877 (rank : 99)
Query Neighborhood Hits	134	Target Neighborhood Hits	701	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CCAR1_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.012785 (rank : 96)
Query Neighborhood Hits	134	Target Neighborhood Hits	444	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

IWS1_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.033268 (rank : 56)
Query Neighborhood Hits	134	Target Neighborhood Hits	1241	Shared Neighborhood Hits	61
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KIF6_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.002591 (rank : 126)
Query Neighborhood Hits	134	Target Neighborhood Hits	271	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

MOES_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.004458 (rank : 118)
Query Neighborhood Hits	134	Target Neighborhood Hits	923	Shared Neighborhood Hits	22
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYO5A_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.002195 (rank : 127)
Query Neighborhood Hits	134	Target Neighborhood Hits	1092	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NPAS3_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.008136 (rank : 107)
Query Neighborhood Hits	134	Target Neighborhood Hits	103	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

PAPOG_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.006476 (rank : 111)
Query Neighborhood Hits	134	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

PRP4B_HUMAN
θ value	6.88961 (rank : 116)	NC score	-0.000223 (rank : 129)
Query Neighborhood Hits	134	Target Neighborhood Hits	1030	Shared Neighborhood Hits	28
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

PSDE_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.009016 (rank : 103)
Query Neighborhood Hits	134	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	O00487, O00176	Gene names	PSMD14, POH1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (26S proteasome-associated PAD1 homolog 1).

PSDE_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.009016 (rank : 104)
Query Neighborhood Hits	134	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	O35593, Q3UB50, Q9CZY6	Gene names	Psmd14, Pad1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (MAD1).

RBBP6_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.030262 (rank : 59)
Query Neighborhood Hits	134	Target Neighborhood Hits	1014	Shared Neighborhood Hits	60
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SEC62_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.032067 (rank : 58)
Query Neighborhood Hits	134	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

TTC16_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.022758 (rank : 74)
Query Neighborhood Hits	134	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

UTP20_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.006186 (rank : 113)
Query Neighborhood Hits	134	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

ARI5B_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.010664 (rank : 102)
Query Neighborhood Hits	134	Target Neighborhood Hits	328	Shared Neighborhood Hits	28
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

GNRP_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.016302 (rank : 88)
Query Neighborhood Hits	134	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

H12_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.013070 (rank : 95)
Query Neighborhood Hits	134	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	P15864	Gene names	Hist1h1c, H1f2
Domain Architecture
Description	Histone H1.2 (H1 VAR.1) (H1c).

H15_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.012694 (rank : 97)
Query Neighborhood Hits	134	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

LRCH4_MOUSE
θ value	8.99809 (rank : 127)	NC score	-0.000855 (rank : 130)
Query Neighborhood Hits	134	Target Neighborhood Hits	302	Shared Neighborhood Hits	2
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

MACOI_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.006041 (rank : 114)
Query Neighborhood Hits	134	Target Neighborhood Hits	620	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MYPT1_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.003009 (rank : 123)
Query Neighborhood Hits	134	Target Neighborhood Hits	539	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NF2L3_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.004873 (rank : 116)
Query Neighborhood Hits	134	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

OR2H1_HUMAN
θ value	8.99809 (rank : 131)	NC score	-0.004895 (rank : 134)
Query Neighborhood Hits	134	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZK4, O43629, O43661, O43662, Q9GZK9	Gene names	OR2H1, OR2H6, OR2H8
Domain Architecture
Description	Olfactory receptor 2H1 (Hs6M1-16) (Olfactory receptor 6-2) (OR6-2) (OLFR42A-9004.14/9026.2).

RPTN_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.022210 (rank : 76)
Query Neighborhood Hits	134	Target Neighborhood Hits	650	Shared Neighborhood Hits	42
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

STK31_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.003863 (rank : 120)
Query Neighborhood Hits	134	Target Neighborhood Hits	570	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

TXND2_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.028285 (rank : 65)
Query Neighborhood Hits	134	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

PDE1C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	134	Target Neighborhood Hits	134	Shared Neighborhood Hits	134
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

PDE1C_MOUSE
NC score	0.993821 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	134	Target Neighborhood Hits	161	Shared Neighborhood Hits	89
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PDE1A_MOUSE
NC score	0.990825 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	Q61481, O35388	Gene names	Pde1a
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).

PDE1A_HUMAN
NC score	0.990753 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	134	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	P54750, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2, Q9C0L3, Q9C0L4, Q9UFX3	Gene names	PDE1A
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE) (hCam-1).

PDE1B_MOUSE
NC score	0.988639 (rank : 5)	θ value	7.7336e-177 (rank : 6)
Query Neighborhood Hits	134	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q01065, O35384	Gene names	Pde1b, Pde1b1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE1B_HUMAN
NC score	0.988485 (rank : 6)	θ value	9.13544e-178 (rank : 5)
Query Neighborhood Hits	134	Target Neighborhood Hits	50	Shared Neighborhood Hits	39
SwissProt Accessions	Q01064, Q92825	Gene names	PDE1B, PDE1B1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE4C_MOUSE
NC score	0.928241 (rank : 7)	θ value	2.40537e-61 (rank : 11)
Query Neighborhood Hits	134	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

PDE4C_HUMAN
NC score	0.925765 (rank : 8)	θ value	4.53632e-60 (rank : 13)
Query Neighborhood Hits	134	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q08493, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6	Gene names	PDE4C
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17) (DPDE1) (PDE21).

PDE4B_HUMAN
NC score	0.924173 (rank : 9)	θ value	2.03627e-60 (rank : 12)
Query Neighborhood Hits	134	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q07343, O15443	Gene names	PDE4B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32).

PDE4D_MOUSE
NC score	0.923936 (rank : 10)	θ value	7.47731e-63 (rank : 8)
Query Neighborhood Hits	134	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

PDE4A_MOUSE
NC score	0.923420 (rank : 11)	θ value	8.26713e-62 (rank : 9)
Query Neighborhood Hits	134	Target Neighborhood Hits	66	Shared Neighborhood Hits	39
SwissProt Accessions	O89084, Q8R078, Q9JHQ4, Q9QX48, Q9QX49, Q9QXI8	Gene names	Pde4a
Domain Architecture
Description	cAMP-dependent 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17).

PDE4D_HUMAN
NC score	0.923249 (rank : 12)	θ value	7.47731e-63 (rank : 7)
Query Neighborhood Hits	134	Target Neighborhood Hits	122	Shared Neighborhood Hits	40
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PDE4A_HUMAN
NC score	0.922757 (rank : 13)	θ value	1.41016e-61 (rank : 10)
Query Neighborhood Hits	134	Target Neighborhood Hits	73	Shared Neighborhood Hits	38
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PDE7B_MOUSE
NC score	0.920064 (rank : 14)	θ value	3.26607e-42 (rank : 21)
Query Neighborhood Hits	134	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXQ1	Gene names	Pde7b
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE7A_MOUSE
NC score	0.919987 (rank : 15)	θ value	3.26607e-42 (rank : 20)
Query Neighborhood Hits	134	Target Neighborhood Hits	39	Shared Neighborhood Hits	38
SwissProt Accessions	P70453, Q9ERB3	Gene names	Pde7a
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (P2A).

PDE7A_HUMAN
NC score	0.919892 (rank : 16)	θ value	3.85808e-43 (rank : 18)
Query Neighborhood Hits	134	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q13946, O15380	Gene names	PDE7A
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (HCP1) (TM22).

PDE7B_HUMAN
NC score	0.919055 (rank : 17)	θ value	1.2411e-41 (rank : 23)
Query Neighborhood Hits	134	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP56	Gene names	PDE7B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE3B_HUMAN
NC score	0.912426 (rank : 18)	θ value	5.38352e-45 (rank : 16)
Query Neighborhood Hits	134	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

PDE9A_MOUSE
NC score	0.907003 (rank : 19)	θ value	2.26708e-35 (rank : 24)
Query Neighborhood Hits	134	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE8A_HUMAN
NC score	0.905375 (rank : 20)	θ value	5.38352e-45 (rank : 17)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O60658, Q969I1, Q96PC9, Q96PD0, Q96PD1, Q9UMB7	Gene names	PDE8A
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17).

PDE9A_HUMAN
NC score	0.903547 (rank : 21)	θ value	6.59618e-35 (rank : 25)
Query Neighborhood Hits	134	Target Neighborhood Hits	93	Shared Neighborhood Hits	38
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE3A_HUMAN
NC score	0.903226 (rank : 22)	θ value	2.85459e-46 (rank : 15)
Query Neighborhood Hits	134	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE8A_MOUSE
NC score	0.902501 (rank : 23)	θ value	6.58091e-43 (rank : 19)
Query Neighborhood Hits	134	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

PDE8B_HUMAN
NC score	0.902227 (rank : 24)	θ value	7.27602e-42 (rank : 22)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95263, Q86XK8, Q8IUJ7, Q8IUJ8, Q8IUJ9, Q8IUK0, Q8N3T2	Gene names	PDE8B
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (EC 3.1.4.17) (HSPDE8B).

PDE3A_MOUSE
NC score	0.902067 (rank : 25)	θ value	1.67352e-46 (rank : 14)
Query Neighborhood Hits	134	Target Neighborhood Hits	115	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE2A_MOUSE
NC score	0.839797 (rank : 26)	θ value	1.85889e-29 (rank : 26)
Query Neighborhood Hits	134	Target Neighborhood Hits	49	Shared Neighborhood Hits	39
SwissProt Accessions	Q922S4, Q8K2U1	Gene names	Pde2a
Domain Architecture	No domain graphic available
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE2A_HUMAN
NC score	0.838994 (rank : 27)	θ value	2.42779e-29 (rank : 27)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	39
SwissProt Accessions	O00408	Gene names	PDE2A
Domain Architecture
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE11_MOUSE
NC score	0.817847 (rank : 28)	θ value	2.96777e-27 (rank : 28)
Query Neighborhood Hits	134	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	P0C1Q2	Gene names	Pde11a
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE11_HUMAN
NC score	0.817547 (rank : 29)	θ value	3.87602e-27 (rank : 29)
Query Neighborhood Hits	134	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCR9, Q53T16, Q96S76, Q9GZY7, Q9HB46, Q9NY45	Gene names	PDE11A
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE10_HUMAN
NC score	0.812873 (rank : 30)	θ value	1.2077e-20 (rank : 38)
Query Neighborhood Hits	134	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y233, Q9Y5T1	Gene names	PDE10A
Domain Architecture
Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17).

PDE5A_MOUSE
NC score	0.800267 (rank : 31)	θ value	6.18819e-25 (rank : 34)
Query Neighborhood Hits	134	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG03	Gene names	Pde5a, Pde5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE5A_HUMAN
NC score	0.795655 (rank : 32)	θ value	8.08199e-25 (rank : 36)
Query Neighborhood Hits	134	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	O76074, O75026, O75887, Q86UI0, Q86V66, Q9Y6Z6	Gene names	PDE5A, PDE5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE6C_MOUSE
NC score	0.789742 (rank : 33)	θ value	7.30988e-26 (rank : 32)
Query Neighborhood Hits	134	Target Neighborhood Hits	45	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6C_HUMAN
NC score	0.789127 (rank : 34)	θ value	2.51237e-26 (rank : 31)
Query Neighborhood Hits	134	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6A_HUMAN
NC score	0.785097 (rank : 35)	θ value	5.06226e-27 (rank : 30)
Query Neighborhood Hits	134	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

PDE6A_MOUSE
NC score	0.780660 (rank : 36)	θ value	1.24688e-25 (rank : 33)
Query Neighborhood Hits	134	Target Neighborhood Hits	45	Shared Neighborhood Hits	38
SwissProt Accessions	P27664	Gene names	Pde6a, Mpa, Pdea
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha).

PDE6B_HUMAN
NC score	0.780134 (rank : 37)	θ value	6.18819e-25 (rank : 35)
Query Neighborhood Hits	134	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	P35913, Q9BWH5	Gene names	PDE6B, PDEB
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase beta-subunit precursor (EC 3.1.4.35) (GMP-PDE beta).

PDE6B_MOUSE
NC score	0.777257 (rank : 38)	θ value	3.07116e-24 (rank : 37)
Query Neighborhood Hits	134	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	P23440	Gene names	Pde6b, Mpb, Pdeb, rd
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor (EC 3.1.4.35) (GMP-PDE beta).

NSBP1_HUMAN
NC score	0.072884 (rank : 39)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	134	Target Neighborhood Hits	251	Shared Neighborhood Hits	33
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

CYLC2_HUMAN
NC score	0.066462 (rank : 40)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	134	Target Neighborhood Hits	223	Shared Neighborhood Hits	31
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DSPP_HUMAN
NC score	0.063061 (rank : 41)	θ value	0.000158464 (rank : 39)
Query Neighborhood Hits	134	Target Neighborhood Hits	645	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_MOUSE
NC score	0.063031 (rank : 42)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	134	Target Neighborhood Hits	491	Shared Neighborhood Hits	35
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CYLC1_HUMAN
NC score	0.057266 (rank : 43)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	134	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

LEO1_HUMAN
NC score	0.045756 (rank : 44)	θ value	0.0148317 (rank : 41)
Query Neighborhood Hits	134	Target Neighborhood Hits	958	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TEX15_HUMAN
NC score	0.045678 (rank : 45)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	134	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

LEO1_MOUSE
NC score	0.045374 (rank : 46)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	134	Target Neighborhood Hits	946	Shared Neighborhood Hits	57
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SFR12_MOUSE
NC score	0.043504 (rank : 47)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	134	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

RBBP6_HUMAN
NC score	0.042087 (rank : 48)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	134	Target Neighborhood Hits	1135	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ARS2_HUMAN
NC score	0.041908 (rank : 49)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	134	Target Neighborhood Hits	186	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

GPTC8_HUMAN
NC score	0.041238 (rank : 50)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	134	Target Neighborhood Hits	366	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

NKTR_HUMAN
NC score	0.040342 (rank : 51)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	134	Target Neighborhood Hits	658	Shared Neighborhood Hits	54
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NPBL_MOUSE
NC score	0.040095 (rank : 52)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	134	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.037229 (rank : 53)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	134	Target Neighborhood Hits	1311	Shared Neighborhood Hits	63
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ARS2_MOUSE
NC score	0.036132 (rank : 54)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	134	Target Neighborhood Hits	212	Shared Neighborhood Hits	26
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

PPIG_HUMAN
NC score	0.033400 (rank : 55)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	134	Target Neighborhood Hits	670	Shared Neighborhood Hits	50
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

IWS1_HUMAN
NC score	0.033268 (rank : 56)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	134	Target Neighborhood Hits	1241	Shared Neighborhood Hits	61
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.032939 (rank : 57)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	134	Target Neighborhood Hits	1258	Shared Neighborhood Hits	56
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SEC62_HUMAN
NC score	0.032067 (rank : 58)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	134	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

RBBP6_MOUSE
NC score	0.030262 (rank : 59)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	134	Target Neighborhood Hits	1014	Shared Neighborhood Hits	60
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RRBP1_MOUSE
NC score	0.029731 (rank : 60)	θ value	0.00509761 (rank : 40)
Query Neighborhood Hits	134	Target Neighborhood Hits	1650	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SRRM2_HUMAN
NC score	0.029414 (rank : 61)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	134	Target Neighborhood Hits	1296	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RNPS1_HUMAN
NC score	0.028824 (rank : 62)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	134	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.028824 (rank : 63)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	134	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SRRM2_MOUSE
NC score	0.028718 (rank : 64)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	134	Target Neighborhood Hits	1470	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TXND2_MOUSE
NC score	0.028285 (rank : 65)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	134	Target Neighborhood Hits	828	Shared Neighborhood Hits	54
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CEBPG_HUMAN
NC score	0.027599 (rank : 66)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	134	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P53567, Q5U052	Gene names	CEBPG
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma).

SEMG2_HUMAN
NC score	0.027121 (rank : 67)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	134	Target Neighborhood Hits	251	Shared Neighborhood Hits	24
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

HTSF1_MOUSE
NC score	0.025113 (rank : 68)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	134	Target Neighborhood Hits	425	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

NKTR_MOUSE
NC score	0.024890 (rank : 69)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	134	Target Neighborhood Hits	417	Shared Neighborhood Hits	42
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CEBPG_MOUSE
NC score	0.024537 (rank : 70)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	134	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P53568	Gene names	Cebpg
Domain Architecture
Description	CCAAT/enhancer-binding protein gamma (C/EBP gamma) (Immunoglobulin enhancer-binding protein 1) (IG/EBP-1) (Granulocyte colony-stimulating factor promoter element 1-binding protein) (GPE1-binding protein) (GPE1-BP).

TCAL5_HUMAN
NC score	0.024514 (rank : 71)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	134	Target Neighborhood Hits	806	Shared Neighborhood Hits	49
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

OXR1_MOUSE
NC score	0.024455 (rank : 72)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	134	Target Neighborhood Hits	516	Shared Neighborhood Hits	33
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

C8AP2_HUMAN
NC score	0.023312 (rank : 73)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	134	Target Neighborhood Hits	548	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

TTC16_HUMAN
NC score	0.022758 (rank : 74)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	134	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TRDN_HUMAN
NC score	0.022285 (rank : 75)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	134	Target Neighborhood Hits	542	Shared Neighborhood Hits	33
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

RPTN_MOUSE
NC score	0.022210 (rank : 76)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	134	Target Neighborhood Hits	650	Shared Neighborhood Hits	42
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

IF4B_HUMAN
NC score	0.021964 (rank : 77)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	134	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

AFF4_MOUSE
NC score	0.021669 (rank : 78)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	134	Target Neighborhood Hits	581	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ICAL_HUMAN
NC score	0.021509 (rank : 79)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	134	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

SEMG1_HUMAN
NC score	0.020941 (rank : 80)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	134	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	P04279, Q6X4I9, Q6Y809, Q6Y822, Q6Y823, Q86U64, Q96QM3	Gene names	SEMG1, SEMG
Domain Architecture
Description	Semenogelin-1 precursor (Semenogelin I) (SGI) [Contains: Alpha- inhibin-92; Alpha-inhibin-31; Seminal basic protein].

IF2P_HUMAN
NC score	0.020187 (rank : 81)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	134	Target Neighborhood Hits	889	Shared Neighborhood Hits	43
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NCKX1_HUMAN
NC score	0.019932 (rank : 82)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	134	Target Neighborhood Hits	223	Shared Neighborhood Hits	20
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

LRRF1_HUMAN
NC score	0.019268 (rank : 83)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	134	Target Neighborhood Hits	625	Shared Neighborhood Hits	29
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

ZN638_HUMAN
NC score	0.017851 (rank : 84)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	134	Target Neighborhood Hits	343	Shared Neighborhood Hits	21
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

SH3BG_MOUSE
NC score	0.017630 (rank : 85)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	134	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WUZ7	Gene names	Sh3bgr
Domain Architecture
Description	SH3 domain-binding glutamic acid-rich protein (SH3BGR protein).

AP3B1_HUMAN
NC score	0.017132 (rank : 86)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	134	Target Neighborhood Hits	283	Shared Neighborhood Hits	28
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

H14_MOUSE
NC score	0.016779 (rank : 87)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	134	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	P43274	Gene names	Hist1h1e, H1f4
Domain Architecture
Description	Histone H1.4 (H1 VAR.2) (H1e).

GNRP_MOUSE
NC score	0.016302 (rank : 88)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	134	Target Neighborhood Hits	191	Shared Neighborhood Hits	10
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

PUM2_HUMAN
NC score	0.015322 (rank : 89)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	134	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

H14_HUMAN
NC score	0.015292 (rank : 90)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	134	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

U2AFM_HUMAN
NC score	0.014742 (rank : 91)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	134	Target Neighborhood Hits	577	Shared Neighborhood Hits	28
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

H13_MOUSE
NC score	0.014630 (rank : 92)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	134	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

B4GN4_MOUSE
NC score	0.014098 (rank : 93)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	134	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

SFR15_HUMAN
NC score	0.013623 (rank : 94)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	134	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

H12_MOUSE
NC score	0.013070 (rank : 95)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	134	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	P15864	Gene names	Hist1h1c, H1f2
Domain Architecture
Description	Histone H1.2 (H1 VAR.1) (H1c).

CCAR1_HUMAN
NC score	0.012785 (rank : 96)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	134	Target Neighborhood Hits	444	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

H15_HUMAN
NC score	0.012694 (rank : 97)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	134	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	P16401, Q14529	Gene names	HIST1H1B, H1F5
Domain Architecture
Description	Histone H1.5 (Histone H1a).

UBP8_HUMAN
NC score	0.010900 (rank : 98)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	134	Target Neighborhood Hits	751	Shared Neighborhood Hits	41
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

BAZ1B_HUMAN
NC score	0.010877 (rank : 99)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	134	Target Neighborhood Hits	701	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

IF2M_MOUSE
NC score	0.010868 (rank : 100)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	134	Target Neighborhood Hits	183	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

HMMR_MOUSE
NC score	0.010780 (rank : 101)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	134	Target Neighborhood Hits	1178	Shared Neighborhood Hits	32
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ARI5B_HUMAN
NC score	0.010664 (rank : 102)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	134	Target Neighborhood Hits	328	Shared Neighborhood Hits	28
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

PSDE_HUMAN
NC score	0.009016 (rank : 103)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	134	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	O00487, O00176	Gene names	PSMD14, POH1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (26S proteasome-associated PAD1 homolog 1).

PSDE_MOUSE
NC score	0.009016 (rank : 104)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	134	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	O35593, Q3UB50, Q9CZY6	Gene names	Psmd14, Pad1
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 14 (26S proteasome regulatory subunit rpn11) (MAD1).

RABE1_MOUSE
NC score	0.008539 (rank : 105)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	134	Target Neighborhood Hits	1105	Shared Neighborhood Hits	30
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

UT14C_HUMAN
NC score	0.008474 (rank : 106)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	134	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

NPAS3_MOUSE
NC score	0.008136 (rank : 107)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	134	Target Neighborhood Hits	103	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

ATX2_HUMAN
NC score	0.007817 (rank : 108)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	134	Target Neighborhood Hits	375	Shared Neighborhood Hits	12
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

NPAS3_HUMAN
NC score	0.007677 (rank : 109)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	134	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

PHF2_MOUSE
NC score	0.006716 (rank : 110)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	134	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PAPOG_MOUSE
NC score	0.006476 (rank : 111)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	134	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PCL9, Q8BZC9	Gene names	Papolg
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase gamma (EC 2.7.7.19) (PAP gamma) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3' adenylating enzyme).

PTPRG_HUMAN
NC score	0.006252 (rank : 112)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	134	Target Neighborhood Hits	231	Shared Neighborhood Hits	13
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

UTP20_HUMAN
NC score	0.006186 (rank : 113)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	134	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

MACOI_MOUSE
NC score	0.006041 (rank : 114)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	134	Target Neighborhood Hits	620	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MOES_HUMAN
NC score	0.005452 (rank : 115)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	134	Target Neighborhood Hits	892	Shared Neighborhood Hits	21
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NF2L3_HUMAN
NC score	0.004873 (rank : 116)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	134	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

TAF5_MOUSE
NC score	0.004461 (rank : 117)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	134	Target Neighborhood Hits	366	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

MOES_MOUSE
NC score	0.004458 (rank : 118)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	134	Target Neighborhood Hits	923	Shared Neighborhood Hits	22
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TAF5_HUMAN
NC score	0.004439 (rank : 119)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	134	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

STK31_HUMAN
NC score	0.003863 (rank : 120)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	134	Target Neighborhood Hits	570	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

FGD3_MOUSE
NC score	0.003835 (rank : 121)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	134	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

MYO5A_MOUSE
NC score	0.003052 (rank : 122)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	134	Target Neighborhood Hits	1117	Shared Neighborhood Hits	27
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYPT1_MOUSE
NC score	0.003009 (rank : 123)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	134	Target Neighborhood Hits	539	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PLEC1_HUMAN
NC score	0.002954 (rank : 124)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	134	Target Neighborhood Hits	1326	Shared Neighborhood Hits	25
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

ADA30_HUMAN
NC score	0.002760 (rank : 125)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	134	Target Neighborhood Hits	391	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

KIF6_HUMAN
NC score	0.002591 (rank : 126)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	134	Target Neighborhood Hits	271	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMV9, Q2MDE3, Q2MDE4, Q5T8J6, Q6ZWE3, Q86T87, Q8WTV4	Gene names	KIF6, C6orf102
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF6.

MYO5A_HUMAN
NC score	0.002195 (rank : 127)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	134	Target Neighborhood Hits	1092	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

KIF14_HUMAN
NC score	0.001815 (rank : 128)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	134	Target Neighborhood Hits	732	Shared Neighborhood Hits	22
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

PRP4B_HUMAN
NC score	-0.000223 (rank : 129)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	134	Target Neighborhood Hits	1030	Shared Neighborhood Hits	28
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

LRCH4_MOUSE
NC score	-0.000855 (rank : 130)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	134	Target Neighborhood Hits	302	Shared Neighborhood Hits	2
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

BMP2K_HUMAN
NC score	-0.001222 (rank : 131)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	134	Target Neighborhood Hits	867	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

TITIN_HUMAN
NC score	-0.001984 (rank : 132)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	134	Target Neighborhood Hits	2923	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ARAF_HUMAN
NC score	-0.004178 (rank : 133)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	134	Target Neighborhood Hits	924	Shared Neighborhood Hits	11
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

OR2H1_HUMAN
NC score	-0.004895 (rank : 134)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	134	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZK4, O43629, O43661, O43662, Q9GZK9	Gene names	OR2H1, OR2H6, OR2H8
Domain Architecture
Description	Olfactory receptor 2H1 (Hs6M1-16) (Olfactory receptor 6-2) (OR6-2) (OLFR42A-9004.14/9026.2).