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Network neighborhood for query Sequence : SAM68_HUMAN

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SAM68_HUMAN
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAM68_MOUSE
θ value	1.68038e-147 (rank : 1)	NC score	0.989054 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_HUMAN
θ value	3.7435e-147 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

KHDR3_HUMAN
θ value	1.40038e-85 (rank : 3)	NC score	0.963004 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	O75525, Q6NUL8, Q9UPA8	Gene names	KHDRBS3, SALP, SLM2
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 3 (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein) (RNA-binding protein T-Star).

KHDR3_MOUSE
θ value	4.98072e-83 (rank : 4)	NC score	0.960190 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R226, O88624	Gene names	Khdrbs3, Salp, Slm2
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 3 (Sam68-like mammalian protein 2) (SLM-2) (RNA-binding protein Etoile).

QKI_HUMAN
θ value	6.38894e-30 (rank : 5)	NC score	0.823474 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PU8, Q2I375, Q5MJQ1, Q969L9, Q96EJ3, Q96KA3, Q96PU6, Q96PU7, Q9P0X6, Q9P0X7, Q9P0X8, Q9P0X9, Q9P0Y0, Q9P0Y1	Gene names	QKI, HKQ
Domain Architecture	No domain graphic available
Description	Quaking protein (Hqk).

QKI_MOUSE
θ value	6.38894e-30 (rank : 6)	NC score	0.823474 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYS9, O88972, Q61110, Q78ZE4, Q78ZE5, Q8K4X9, Q8K4Y0, Q9CW34, Q9QUH4, Q9R2A8, Q9Z246	Gene names	Qki, Qk, Qk1, Qka1
Domain Architecture	No domain graphic available
Description	Quaking protein (qkI).

SF01_HUMAN
θ value	5.08577e-11 (rank : 7)	NC score	0.539670 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	8.67504e-11 (rank : 8)	NC score	0.543049 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	240	Shared Neighborhood Hits	26
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

FUBP3_HUMAN
θ value	0.00390308 (rank : 9)	NC score	0.195068 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP2_HUMAN
θ value	0.0193708 (rank : 10)	NC score	0.179537 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

IF2B2_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.204090 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	148	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

FUBP1_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.169553 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.169808 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	144	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

K1688_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.047325 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

NOVA2_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.168973 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

DCC_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.027339 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	896	Shared Neighborhood Hits	13
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

IF2B2_HUMAN
θ value	0.21417 (rank : 17)	NC score	0.179144 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

PCBP3_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.147908 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_MOUSE
θ value	0.21417 (rank : 19)	NC score	0.147980 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

RFIP1_MOUSE
θ value	0.21417 (rank : 20)	NC score	0.036894 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

NOVA1_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.161286 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

PCBP1_HUMAN
θ value	0.279714 (rank : 22)	NC score	0.143753 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.143753 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

BCAR1_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.042873 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	554	Shared Neighborhood Hits	16
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MYO15_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.017849 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	671	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NPAS4_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.038902 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PCBP2_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.138829 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.138046 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

SPEG_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.009830 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	1959	Shared Neighborhood Hits	27
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CABL2_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.034598 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

M3K11_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.005384 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	1136	Shared Neighborhood Hits	16
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

NPAS4_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.035948 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	214	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PCBP4_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.135409 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.135809 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

SPI1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.019208 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P17947	Gene names	SPI1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein).

CEL_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.023511 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	896	Shared Neighborhood Hits	22
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

RGS3_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.024838 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	1375	Shared Neighborhood Hits	26
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RKHD1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.096537 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

ZN692_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.000850 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

AKAP2_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.017901 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

CB025_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.024607 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LS1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C2orf25 homolog, mitochondrial precursor.

SEM6C_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.007899 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	352	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

APC_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.021805 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	603	Shared Neighborhood Hits	14
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PCLO_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.020823 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	2275	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RPTN_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.020924 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	406	Shared Neighborhood Hits	6
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SPHK2_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.017460 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

ZCH14_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.021401 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

DCC_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.016777 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	583	Shared Neighborhood Hits	7
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

EP15R_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.007073 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	1135	Shared Neighborhood Hits	9
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

HNRPG_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.014286 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	P38159, Q5JQ67, Q969R3	Gene names	RBMX, HNRPG, RBMXP1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome) (Glycoprotein p43).

PNPT1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.036291 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

RPTN_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.009349 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

ZN385_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.019371 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	614	Shared Neighborhood Hits	14
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

AXN2_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.011022 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CIC_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.017586 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	992	Shared Neighborhood Hits	23
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DDX53_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.014313 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

MTR1L_HUMAN
θ value	6.88961 (rank : 57)	NC score	-0.000659 (rank : 74)
Query Neighborhood Hits	68	Target Neighborhood Hits	1180	Shared Neighborhood Hits	5
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

OGFR_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.025840 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	1582	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SCAP_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.017948 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

AMBN_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.013303 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O55189	Gene names	Ambn
Domain Architecture
Description	Ameloblastin precursor.

ATX2L_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.018482 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BCAR1_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.022592 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	438	Shared Neighborhood Hits	13
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CTDP1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.012709 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	416	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DPYL4_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.004820 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O14531, O00240, Q5T0Q7	Gene names	DPYSL4, CRMP3, ULIP4
Domain Architecture
Description	Dihydropyrimidinase-related protein 4 (DRP-4) (Collapsin response mediator protein 3) (CRMP-3) (UNC33-like phosphoprotein 4) (ULIP4 protein).

MUC1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.019475 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	975	Shared Neighborhood Hits	23
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PNPT1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.030603 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

TARA_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.009090 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	1133	Shared Neighborhood Hits	18
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAU_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.012416 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	448	Shared Neighborhood Hits	13
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

HNRPK_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.093073 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.093073 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

TDRKH_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.070419 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.070407 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

VIGLN_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.053103 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.053233 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

Hits sorted by NC score

SAM68_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.7435e-147 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
NC score	0.989054 (rank : 2)	θ value	1.68038e-147 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

KHDR3_HUMAN
NC score	0.963004 (rank : 3)	θ value	1.40038e-85 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	O75525, Q6NUL8, Q9UPA8	Gene names	KHDRBS3, SALP, SLM2
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 3 (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein) (RNA-binding protein T-Star).

KHDR3_MOUSE
NC score	0.960190 (rank : 4)	θ value	4.98072e-83 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R226, O88624	Gene names	Khdrbs3, Salp, Slm2
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 3 (Sam68-like mammalian protein 2) (SLM-2) (RNA-binding protein Etoile).

QKI_HUMAN
NC score	0.823474 (rank : 5)	θ value	6.38894e-30 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PU8, Q2I375, Q5MJQ1, Q969L9, Q96EJ3, Q96KA3, Q96PU6, Q96PU7, Q9P0X6, Q9P0X7, Q9P0X8, Q9P0X9, Q9P0Y0, Q9P0Y1	Gene names	QKI, HKQ
Domain Architecture	No domain graphic available
Description	Quaking protein (Hqk).

QKI_MOUSE
NC score	0.823474 (rank : 6)	θ value	6.38894e-30 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	33	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYS9, O88972, Q61110, Q78ZE4, Q78ZE5, Q8K4X9, Q8K4Y0, Q9CW34, Q9QUH4, Q9R2A8, Q9Z246	Gene names	Qki, Qk, Qk1, Qka1
Domain Architecture	No domain graphic available
Description	Quaking protein (qkI).

SF01_MOUSE
NC score	0.543049 (rank : 7)	θ value	8.67504e-11 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	240	Shared Neighborhood Hits	26
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SF01_HUMAN
NC score	0.539670 (rank : 8)	θ value	5.08577e-11 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

IF2B2_MOUSE
NC score	0.204090 (rank : 9)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	148	Shared Neighborhood Hits	27
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

FUBP3_HUMAN
NC score	0.195068 (rank : 10)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP2_HUMAN
NC score	0.179537 (rank : 11)	θ value	0.0193708 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

IF2B2_HUMAN
NC score	0.179144 (rank : 12)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

FUBP1_MOUSE
NC score	0.169808 (rank : 13)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	144	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.169553 (rank : 14)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

NOVA2_HUMAN
NC score	0.168973 (rank : 15)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

NOVA1_HUMAN
NC score	0.161286 (rank : 16)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

PCBP3_MOUSE
NC score	0.147980 (rank : 17)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_HUMAN
NC score	0.147908 (rank : 18)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP1_HUMAN
NC score	0.143753 (rank : 19)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
NC score	0.143753 (rank : 20)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP2_HUMAN
NC score	0.138829 (rank : 21)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
NC score	0.138046 (rank : 22)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP4_MOUSE
NC score	0.135809 (rank : 23)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_HUMAN
NC score	0.135409 (rank : 24)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

RKHD1_HUMAN
NC score	0.096537 (rank : 25)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

HNRPK_HUMAN
NC score	0.093073 (rank : 26)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.093073 (rank : 27)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

TDRKH_HUMAN
NC score	0.070419 (rank : 28)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
NC score	0.070407 (rank : 29)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

VIGLN_MOUSE
NC score	0.053233 (rank : 30)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	68	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_HUMAN
NC score	0.053103 (rank : 31)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

K1688_HUMAN
NC score	0.047325 (rank : 32)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

BCAR1_HUMAN
NC score	0.042873 (rank : 33)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	554	Shared Neighborhood Hits	16
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

NPAS4_MOUSE
NC score	0.038902 (rank : 34)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

RFIP1_MOUSE
NC score	0.036894 (rank : 35)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

PNPT1_HUMAN
NC score	0.036291 (rank : 36)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

NPAS4_HUMAN
NC score	0.035948 (rank : 37)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	214	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

CABL2_HUMAN
NC score	0.034598 (rank : 38)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTV7, Q5JWL0, Q9BYK0	Gene names	CABLES2, C20orf150
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

PNPT1_MOUSE
NC score	0.030603 (rank : 39)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

DCC_MOUSE
NC score	0.027339 (rank : 40)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	896	Shared Neighborhood Hits	13
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

OGFR_HUMAN
NC score	0.025840 (rank : 41)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	1582	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RGS3_HUMAN
NC score	0.024838 (rank : 42)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	1375	Shared Neighborhood Hits	26
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CB025_MOUSE
NC score	0.024607 (rank : 43)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LS1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C2orf25 homolog, mitochondrial precursor.

CEL_HUMAN
NC score	0.023511 (rank : 44)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	896	Shared Neighborhood Hits	22
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

BCAR1_MOUSE
NC score	0.022592 (rank : 45)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	438	Shared Neighborhood Hits	13
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

APC_HUMAN
NC score	0.021805 (rank : 46)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	603	Shared Neighborhood Hits	14
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ZCH14_HUMAN
NC score	0.021401 (rank : 47)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

RPTN_HUMAN
NC score	0.020924 (rank : 48)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	406	Shared Neighborhood Hits	6
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

PCLO_MOUSE
NC score	0.020823 (rank : 49)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	2275	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MUC1_HUMAN
NC score	0.019475 (rank : 50)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	975	Shared Neighborhood Hits	23
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ZN385_HUMAN
NC score	0.019371 (rank : 51)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	614	Shared Neighborhood Hits	14
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SPI1_HUMAN
NC score	0.019208 (rank : 52)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P17947	Gene names	SPI1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein).

ATX2L_HUMAN
NC score	0.018482 (rank : 53)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	443	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

SCAP_HUMAN
NC score	0.017948 (rank : 54)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

AKAP2_HUMAN
NC score	0.017901 (rank : 55)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	507	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

MYO15_HUMAN
NC score	0.017849 (rank : 56)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	671	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CIC_HUMAN
NC score	0.017586 (rank : 57)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	992	Shared Neighborhood Hits	23
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SPHK2_MOUSE
NC score	0.017460 (rank : 58)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

DCC_HUMAN
NC score	0.016777 (rank : 59)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	583	Shared Neighborhood Hits	7
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DDX53_HUMAN
NC score	0.014313 (rank : 60)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

HNRPG_HUMAN
NC score	0.014286 (rank : 61)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	P38159, Q5JQ67, Q969R3	Gene names	RBMX, HNRPG, RBMXP1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome) (Glycoprotein p43).

AMBN_MOUSE
NC score	0.013303 (rank : 62)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O55189	Gene names	Ambn
Domain Architecture
Description	Ameloblastin precursor.

CTDP1_HUMAN
NC score	0.012709 (rank : 63)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	416	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

TAU_HUMAN
NC score	0.012416 (rank : 64)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	448	Shared Neighborhood Hits	13
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

AXN2_MOUSE
NC score	0.011022 (rank : 65)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

SPEG_MOUSE
NC score	0.009830 (rank : 66)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	1959	Shared Neighborhood Hits	27
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RPTN_MOUSE
NC score	0.009349 (rank : 67)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TARA_MOUSE
NC score	0.009090 (rank : 68)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	1133	Shared Neighborhood Hits	18
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SEM6C_MOUSE
NC score	0.007899 (rank : 69)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	352	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

EP15R_MOUSE
NC score	0.007073 (rank : 70)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	1135	Shared Neighborhood Hits	9
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

M3K11_HUMAN
NC score	0.005384 (rank : 71)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	1136	Shared Neighborhood Hits	16
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

DPYL4_HUMAN
NC score	0.004820 (rank : 72)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O14531, O00240, Q5T0Q7	Gene names	DPYSL4, CRMP3, ULIP4
Domain Architecture
Description	Dihydropyrimidinase-related protein 4 (DRP-4) (Collapsin response mediator protein 3) (CRMP-3) (UNC33-like phosphoprotein 4) (ULIP4 protein).

ZN692_HUMAN
NC score	0.000850 (rank : 73)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

MTR1L_HUMAN
NC score	-0.000659 (rank : 74)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	1180	Shared Neighborhood Hits	5
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).