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Network neighborhood for query Sequence : PCBP2_MOUSE

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PCBP2_MOUSE
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PCBP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999586 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	43
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP1_HUMAN
θ value	5.94893e-161 (rank : 3)	NC score	0.996271 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	37	Shared Neighborhood Hits	32
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
θ value	5.94893e-161 (rank : 4)	NC score	0.996271 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	37	Shared Neighborhood Hits	32
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP3_HUMAN
θ value	1.20704e-137 (rank : 5)	NC score	0.988013 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_MOUSE
θ value	1.20704e-137 (rank : 6)	NC score	0.988027 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP4_MOUSE
θ value	2.72037e-97 (rank : 7)	NC score	0.979568 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_HUMAN
θ value	1.76329e-96 (rank : 8)	NC score	0.977849 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

HNRPK_HUMAN
θ value	1.42001e-37 (rank : 9)	NC score	0.864804 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	1.42001e-37 (rank : 10)	NC score	0.864804 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

NOVA1_HUMAN
θ value	3.17815e-21 (rank : 11)	NC score	0.779275 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

FUBP3_HUMAN
θ value	3.40345e-15 (rank : 12)	NC score	0.658079 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

NOVA2_HUMAN
θ value	2.88119e-14 (rank : 13)	NC score	0.773170 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

IF2B2_MOUSE
θ value	1.42992e-13 (rank : 14)	NC score	0.601141 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

IF2B2_HUMAN
θ value	4.16044e-13 (rank : 15)	NC score	0.604083 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

FUBP1_MOUSE
θ value	5.43371e-13 (rank : 16)	NC score	0.611453 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP2_HUMAN
θ value	5.43371e-13 (rank : 17)	NC score	0.627118 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	145	Shared Neighborhood Hits	32
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

FUBP1_HUMAN
θ value	7.09661e-13 (rank : 18)	NC score	0.610377 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

TDRKH_HUMAN
θ value	1.99992e-07 (rank : 19)	NC score	0.456225 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
θ value	4.45536e-07 (rank : 20)	NC score	0.453831 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

VIGLN_HUMAN
θ value	4.92598e-06 (rank : 21)	NC score	0.378367 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
θ value	8.40245e-06 (rank : 22)	NC score	0.378487 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

SMCA4_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.021228 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	597	Shared Neighborhood Hits	6
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

AKAP1_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.215765 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
θ value	0.21417 (rank : 25)	NC score	0.201855 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

FXR2_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.104066 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

SAM68_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.138046 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.136039 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

DDX43_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.044386 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX53_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.057891 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	124	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

SH2D3_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.018234 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

EGFR_HUMAN
θ value	1.81305 (rank : 32)	NC score	-0.000769 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	939	Shared Neighborhood Hits	2
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

CSTN1_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.009408 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

LRP1B_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.005972 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	606	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SON_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.012480 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	1568	Shared Neighborhood Hits	13
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PDE3A_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.014731 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PO6F2_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.010824 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	639	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

ARI1A_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.010186 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	787	Shared Neighborhood Hits	6
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

FXR1_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.098598 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FXR1_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.096391 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

LRP1B_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.005119 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SON_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.009087 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	957	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

UBXD1_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.024439 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

FXR2_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.054409 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	66	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

WASIP_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.011170 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SULF1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.004435 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

WT1_HUMAN
θ value	8.99809 (rank : 47)	NC score	-0.002265 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	720	Shared Neighborhood Hits	4
SwissProt Accessions	P19544, Q15881, Q16256, Q16575, Q8IYZ5	Gene names	WT1
Domain Architecture
Description	Wilms' tumor protein (WT33).

FMR1_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.063587 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FMR1_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.062378 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

RKHD1_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.212121 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

Hits sorted by NC score

PCBP2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP2_HUMAN
NC score	0.999586 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	43
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP1_HUMAN
NC score	0.996271 (rank : 3)	θ value	5.94893e-161 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	37	Shared Neighborhood Hits	32
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
NC score	0.996271 (rank : 4)	θ value	5.94893e-161 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	37	Shared Neighborhood Hits	32
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP3_MOUSE
NC score	0.988027 (rank : 5)	θ value	1.20704e-137 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_HUMAN
NC score	0.988013 (rank : 6)	θ value	1.20704e-137 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP4_MOUSE
NC score	0.979568 (rank : 7)	θ value	2.72037e-97 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	31
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_HUMAN
NC score	0.977849 (rank : 8)	θ value	1.76329e-96 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

HNRPK_HUMAN
NC score	0.864804 (rank : 9)	θ value	1.42001e-37 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.864804 (rank : 10)	θ value	1.42001e-37 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

NOVA1_HUMAN
NC score	0.779275 (rank : 11)	θ value	3.17815e-21 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

NOVA2_HUMAN
NC score	0.773170 (rank : 12)	θ value	2.88119e-14 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

FUBP3_HUMAN
NC score	0.658079 (rank : 13)	θ value	3.40345e-15 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP2_HUMAN
NC score	0.627118 (rank : 14)	θ value	5.43371e-13 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	145	Shared Neighborhood Hits	32
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

FUBP1_MOUSE
NC score	0.611453 (rank : 15)	θ value	5.43371e-13 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.610377 (rank : 16)	θ value	7.09661e-13 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	136	Shared Neighborhood Hits	33
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

IF2B2_HUMAN
NC score	0.604083 (rank : 17)	θ value	4.16044e-13 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	142	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
NC score	0.601141 (rank : 18)	θ value	1.42992e-13 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	148	Shared Neighborhood Hits	31
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

TDRKH_HUMAN
NC score	0.456225 (rank : 19)	θ value	1.99992e-07 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
NC score	0.453831 (rank : 20)	θ value	4.45536e-07 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

VIGLN_MOUSE
NC score	0.378487 (rank : 21)	θ value	8.40245e-06 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_HUMAN
NC score	0.378367 (rank : 22)	θ value	4.92598e-06 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

AKAP1_HUMAN
NC score	0.215765 (rank : 23)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

RKHD1_HUMAN
NC score	0.212121 (rank : 24)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

AKAP1_MOUSE
NC score	0.201855 (rank : 25)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

SAM68_HUMAN
NC score	0.138046 (rank : 26)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
NC score	0.136039 (rank : 27)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

FXR2_HUMAN
NC score	0.104066 (rank : 28)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR1_HUMAN
NC score	0.098598 (rank : 29)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FXR1_MOUSE
NC score	0.096391 (rank : 30)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

FMR1_HUMAN
NC score	0.063587 (rank : 31)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FMR1_MOUSE
NC score	0.062378 (rank : 32)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

DDX53_HUMAN
NC score	0.057891 (rank : 33)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	124	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

FXR2_MOUSE
NC score	0.054409 (rank : 34)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	66	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

DDX43_HUMAN
NC score	0.044386 (rank : 35)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

UBXD1_HUMAN
NC score	0.024439 (rank : 36)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

SMCA4_HUMAN
NC score	0.021228 (rank : 37)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	597	Shared Neighborhood Hits	6
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SH2D3_HUMAN
NC score	0.018234 (rank : 38)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

PDE3A_MOUSE
NC score	0.014731 (rank : 39)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

SON_HUMAN
NC score	0.012480 (rank : 40)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	1568	Shared Neighborhood Hits	13
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WASIP_MOUSE
NC score	0.011170 (rank : 41)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PO6F2_MOUSE
NC score	0.010824 (rank : 42)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	639	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

ARI1A_HUMAN
NC score	0.010186 (rank : 43)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	787	Shared Neighborhood Hits	6
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CSTN1_MOUSE
NC score	0.009408 (rank : 44)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

SON_MOUSE
NC score	0.009087 (rank : 45)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	957	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

LRP1B_MOUSE
NC score	0.005972 (rank : 46)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	606	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_HUMAN
NC score	0.005119 (rank : 47)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	602	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SULF1_MOUSE
NC score	0.004435 (rank : 48)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K007, Q8BLJ0, Q8C1D3	Gene names	Sulf1
Domain Architecture
Description	Extracellular sulfatase Sulf-1 precursor (EC 3.1.6.-) (MSulf-1).

EGFR_HUMAN
NC score	-0.000769 (rank : 49)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	939	Shared Neighborhood Hits	2
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

WT1_HUMAN
NC score	-0.002265 (rank : 50)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	720	Shared Neighborhood Hits	4
SwissProt Accessions	P19544, Q15881, Q16256, Q16575, Q8IYZ5	Gene names	WT1
Domain Architecture
Description	Wilms' tumor protein (WT33).