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Network neighborhood for query Sequence : DMRTC_HUMAN

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DMRTC_HUMAN
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DMRTC_HUMAN
θ value	4.34313e-95 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

DMRTC_MOUSE
θ value	4.88048e-38 (rank : 2)	NC score	0.925406 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D9R7, Q2PMY0, Q9D5U3	Gene names	Dmrtc1, Dmrt8.1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1 (Doublesex- and mab-3-related transcription factor 8.1).

DMRTD_HUMAN
θ value	6.40375e-22 (rank : 3)	NC score	0.628815 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DMRTD_MOUSE
θ value	8.36355e-22 (rank : 4)	NC score	0.661781 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

PHC3_HUMAN
θ value	0.0148317 (rank : 5)	NC score	0.138609 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PHC3_MOUSE
θ value	0.0431538 (rank : 6)	NC score	0.122189 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

TCGAP_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.039956 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

EDD1_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.070794 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	0.365318 (rank : 9)	NC score	0.070761 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

CJ078_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.039691 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	559	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

JIP1_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.022581 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

MCR_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.009914 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

SPR1A_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.022071 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

WNK2_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.003765 (rank : 21)
Query Neighborhood Hits	15	Target Neighborhood Hits	1407	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

IQEC3_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.009211 (rank : 20)
Query Neighborhood Hits	15	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

DMRT1_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.164704 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5R6, Q8IW77	Gene names	DMRT1, DMT1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1 (DM domain expressed in testis protein 1).

DMRT1_MOUSE
θ value	θ > 10 (rank : 17)	NC score	0.166374 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

DMRT2_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.214473 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5R5	Gene names	DMRT2, DSXL2
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2).

DMRTA_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.157541 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

DMRTA_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.155624 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFG4	Gene names	Dmrta1, Dmrt4
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4).

PHC2_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.066775 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	388	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

Hits sorted by NC score

DMRTC_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.34313e-95 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

DMRTC_MOUSE
NC score	0.925406 (rank : 2)	θ value	4.88048e-38 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D9R7, Q2PMY0, Q9D5U3	Gene names	Dmrtc1, Dmrt8.1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1 (Doublesex- and mab-3-related transcription factor 8.1).

DMRTD_MOUSE
NC score	0.661781 (rank : 3)	θ value	8.36355e-22 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

DMRTD_HUMAN
NC score	0.628815 (rank : 4)	θ value	6.40375e-22 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

DMRT2_HUMAN
NC score	0.214473 (rank : 5)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5R5	Gene names	DMRT2, DSXL2
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 2 (Doublesex-like 2 protein) (DSXL-2).

DMRT1_MOUSE
NC score	0.166374 (rank : 6)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

DMRT1_HUMAN
NC score	0.164704 (rank : 7)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5R6, Q8IW77	Gene names	DMRT1, DMT1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1 (DM domain expressed in testis protein 1).

DMRTA_HUMAN
NC score	0.157541 (rank : 8)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

DMRTA_MOUSE
NC score	0.155624 (rank : 9)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	15	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFG4	Gene names	Dmrta1, Dmrt4
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4).

PHC3_HUMAN
NC score	0.138609 (rank : 10)	θ value	0.0148317 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PHC3_MOUSE
NC score	0.122189 (rank : 11)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

EDD1_HUMAN
NC score	0.070794 (rank : 12)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
NC score	0.070761 (rank : 13)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	167	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

PHC2_HUMAN
NC score	0.066775 (rank : 14)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	15	Target Neighborhood Hits	388	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

TCGAP_HUMAN
NC score	0.039956 (rank : 15)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	5
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CJ078_MOUSE
NC score	0.039691 (rank : 16)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	559	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

JIP1_HUMAN
NC score	0.022581 (rank : 17)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

SPR1A_HUMAN
NC score	0.022071 (rank : 18)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

MCR_HUMAN
NC score	0.009914 (rank : 19)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

IQEC3_MOUSE
NC score	0.009211 (rank : 20)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

WNK2_HUMAN
NC score	0.003765 (rank : 21)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	1407	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).