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Network neighborhood for query Sequence : NU205_HUMAN

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NU205_HUMAN
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NU205_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

MRP3_HUMAN
θ value	0.0736092 (rank : 2)	NC score	0.028806 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

EPHA1_HUMAN
θ value	1.06291 (rank : 3)	NC score	0.008442 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	997	Shared Neighborhood Hits	4
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

STK36_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.008233 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

K0841_MOUSE
θ value	1.38821 (rank : 5)	NC score	0.049298 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D786, Q5HZI7, Q6ZQ35, Q8CIK2	Gene names	Kiaa0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

CEP35_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.030772 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	811	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CP250_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.012031 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	1583	Shared Neighborhood Hits	5
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

RDH1_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.025431 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q92781, Q8TAI2	Gene names	RDH5, RDH1
Domain Architecture
Description	11-cis retinol dehydrogenase (EC 1.1.1.105) (11-cis RDH).

CRAL_MOUSE
θ value	3.0926 (rank : 9)	NC score	0.028954 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z275	Gene names	Rlbp1
Domain Architecture
Description	Cellular retinaldehyde-binding protein (CRALBP).

KAPCB_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.005411 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	837	Shared Neighborhood Hits	4
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

HMDH_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.029369 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q01237, Q5U4I2	Gene names	Hmgcr
Domain Architecture	No domain graphic available
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

RBPMS_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.031656 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q93062, Q92516, Q92517, Q92518, Q96J26	Gene names	RBPMS
Domain Architecture
Description	RNA-binding protein with multiple splicing (RBP-MS).

TEX28_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.028797 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O15482	Gene names	CXorf2, TEX28
Domain Architecture	No domain graphic available
Description	Testis-specific protein TEX28.

FYCO1_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.008122 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	1149	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

HUWE1_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.015106 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	443	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.015122 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	406	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

PRP4_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.010012 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PTN21_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.006934 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

CIR1A_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.021570 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

CIR1A_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.021356 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

PRP4_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.009198 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

T23O_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.019971 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

Hits sorted by NC score

NU205_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

K0841_MOUSE
NC score	0.049298 (rank : 2)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D786, Q5HZI7, Q6ZQ35, Q8CIK2	Gene names	Kiaa0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

RBPMS_HUMAN
NC score	0.031656 (rank : 3)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q93062, Q92516, Q92517, Q92518, Q96J26	Gene names	RBPMS
Domain Architecture
Description	RNA-binding protein with multiple splicing (RBP-MS).

CEP35_HUMAN
NC score	0.030772 (rank : 4)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	811	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

HMDH_MOUSE
NC score	0.029369 (rank : 5)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q01237, Q5U4I2	Gene names	Hmgcr
Domain Architecture	No domain graphic available
Description	3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34) (HMG-CoA reductase).

CRAL_MOUSE
NC score	0.028954 (rank : 6)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z275	Gene names	Rlbp1
Domain Architecture
Description	Cellular retinaldehyde-binding protein (CRALBP).

MRP3_HUMAN
NC score	0.028806 (rank : 7)	θ value	0.0736092 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

TEX28_HUMAN
NC score	0.028797 (rank : 8)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O15482	Gene names	CXorf2, TEX28
Domain Architecture	No domain graphic available
Description	Testis-specific protein TEX28.

RDH1_HUMAN
NC score	0.025431 (rank : 9)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q92781, Q8TAI2	Gene names	RDH5, RDH1
Domain Architecture
Description	11-cis retinol dehydrogenase (EC 1.1.1.105) (11-cis RDH).

CIR1A_HUMAN
NC score	0.021570 (rank : 10)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

CIR1A_MOUSE
NC score	0.021356 (rank : 11)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

T23O_MOUSE
NC score	0.019971 (rank : 12)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P48776	Gene names	Tdo2, Tdo
Domain Architecture
Description	Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (TO) (Tryptophan pyrrolase) (Tryptophanase) (Tryptophan oxygenase) (Tryptamin 2,3-dioxygenase) (TRPO).

HUWE1_MOUSE
NC score	0.015122 (rank : 13)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	406	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.015106 (rank : 14)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	443	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

CP250_MOUSE
NC score	0.012031 (rank : 15)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	1583	Shared Neighborhood Hits	5
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

PRP4_MOUSE
NC score	0.010012 (rank : 16)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PRP4_HUMAN
NC score	0.009198 (rank : 17)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

EPHA1_HUMAN
NC score	0.008442 (rank : 18)	θ value	1.06291 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	997	Shared Neighborhood Hits	4
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

STK36_HUMAN
NC score	0.008233 (rank : 19)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

FYCO1_HUMAN
NC score	0.008122 (rank : 20)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	1149	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

PTN21_MOUSE
NC score	0.006934 (rank : 21)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

KAPCB_HUMAN
NC score	0.005411 (rank : 22)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	837	Shared Neighborhood Hits	4
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).