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Network neighborhood for query Sequence : ISY1_HUMAN

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ISY1_HUMAN
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ISY1_HUMAN
θ value	2.49938e-159 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

ISY1_MOUSE
θ value	7.07634e-138 (rank : 2)	NC score	0.990131 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

OPTN_HUMAN
θ value	0.163984 (rank : 3)	NC score	0.067045 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	827	Shared Neighborhood Hits	16
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

WNK2_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.014401 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	1407	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

KTN1_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.043813 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	1324	Shared Neighborhood Hits	17
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SPTA2_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.037630 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	888	Shared Neighborhood Hits	14
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DDX27_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.034308 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

RIMB1_MOUSE
θ value	0.279714 (rank : 8)	NC score	0.044250 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	1376	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TTBK1_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.015330 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	1058	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

KTN1_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.041737 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	1197	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

SPRL1_MOUSE
θ value	1.38821 (rank : 11)	NC score	0.051982 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CCD41_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.030692 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	1139	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

DHX16_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.026235 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

GOGA3_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.030015 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	1437	Shared Neighborhood Hits	16
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

OPTN_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.043752 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	1120	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CCD21_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.037780 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	1228	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CL025_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.050705 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

MAST3_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.004977 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	1128	Shared Neighborhood Hits	4
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

CNTRB_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.032213 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	1029	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NALP5_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.014435 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

DDX27_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.023643 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

PKHA6_MOUSE
θ value	5.27518 (rank : 22)	NC score	0.016614 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	591	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RBBP5_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.026787 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	372	Shared Neighborhood Hits	5
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

RBNS5_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.020283 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

CCD21_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.038415 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

LAMB1_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.013998 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	919	Shared Neighborhood Hits	13
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

ALDOC_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.010947 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P09972	Gene names	ALDOC, ALDC
Domain Architecture
Description	Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase).

BAT3_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.013669 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	490	Shared Neighborhood Hits	3
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAZ2B_HUMAN
θ value	8.99809 (rank : 29)	NC score	0.019920 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	803	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

DICER_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.020996 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

KCNH2_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.006744 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	165	Shared Neighborhood Hits	2
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

Hits sorted by NC score

ISY1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.49938e-159 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

ISY1_MOUSE
NC score	0.990131 (rank : 2)	θ value	7.07634e-138 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

OPTN_HUMAN
NC score	0.067045 (rank : 3)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	827	Shared Neighborhood Hits	16
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

SPRL1_MOUSE
NC score	0.051982 (rank : 4)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	403	Shared Neighborhood Hits	8
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CL025_HUMAN
NC score	0.050705 (rank : 5)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	179	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

RIMB1_MOUSE
NC score	0.044250 (rank : 6)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	1376	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

KTN1_MOUSE
NC score	0.043813 (rank : 7)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	1324	Shared Neighborhood Hits	17
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

OPTN_MOUSE
NC score	0.043752 (rank : 8)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	1120	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

KTN1_HUMAN
NC score	0.041737 (rank : 9)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	1197	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CCD21_MOUSE
NC score	0.038415 (rank : 10)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	1135	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_HUMAN
NC score	0.037780 (rank : 11)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	1228	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

SPTA2_HUMAN
NC score	0.037630 (rank : 12)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	888	Shared Neighborhood Hits	14
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DDX27_MOUSE
NC score	0.034308 (rank : 13)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

CNTRB_MOUSE
NC score	0.032213 (rank : 14)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	1029	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CCD41_HUMAN
NC score	0.030692 (rank : 15)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	1139	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

GOGA3_MOUSE
NC score	0.030015 (rank : 16)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	1437	Shared Neighborhood Hits	16
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

RBBP5_HUMAN
NC score	0.026787 (rank : 17)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	372	Shared Neighborhood Hits	5
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

DHX16_HUMAN
NC score	0.026235 (rank : 18)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DDX27_HUMAN
NC score	0.023643 (rank : 19)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DICER_MOUSE
NC score	0.020996 (rank : 20)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RBNS5_HUMAN
NC score	0.020283 (rank : 21)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

BAZ2B_HUMAN
NC score	0.019920 (rank : 22)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	803	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PKHA6_MOUSE
NC score	0.016614 (rank : 23)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	591	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

TTBK1_HUMAN
NC score	0.015330 (rank : 24)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	1058	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

NALP5_MOUSE
NC score	0.014435 (rank : 25)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

WNK2_HUMAN
NC score	0.014401 (rank : 26)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	1407	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

LAMB1_MOUSE
NC score	0.013998 (rank : 27)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	919	Shared Neighborhood Hits	13
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BAT3_HUMAN
NC score	0.013669 (rank : 28)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	490	Shared Neighborhood Hits	3
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

ALDOC_HUMAN
NC score	0.010947 (rank : 29)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P09972	Gene names	ALDOC, ALDC
Domain Architecture
Description	Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase).

KCNH2_MOUSE
NC score	0.006744 (rank : 30)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	165	Shared Neighborhood Hits	2
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MAST3_HUMAN
NC score	0.004977 (rank : 31)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	1128	Shared Neighborhood Hits	4
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).