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Network neighborhood for query Sequence : ISY1_MOUSE

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ISY1_MOUSE
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ISY1_MOUSE
θ value	4.00889e-141 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

ISY1_HUMAN
θ value	7.07634e-138 (rank : 2)	NC score	0.990131 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

OPTN_HUMAN
θ value	0.0961366 (rank : 3)	NC score	0.077840 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	827	Shared Neighborhood Hits	26
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

DDX27_MOUSE
θ value	0.21417 (rank : 4)	NC score	0.035594 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

SPRL1_MOUSE
θ value	0.21417 (rank : 5)	NC score	0.062355 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SPTA2_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.039811 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	888	Shared Neighborhood Hits	19
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

CDC37_HUMAN
θ value	0.279714 (rank : 7)	NC score	0.059742 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	506	Shared Neighborhood Hits	21
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CCD21_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.053598 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	1228	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	0.62314 (rank : 9)	NC score	0.055835 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

OPTN_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.053990 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	1120	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

KTN1_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.045867 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	1324	Shared Neighborhood Hits	27
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SMC2_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.037276 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CNTRB_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.041616 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	1029	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GOGA3_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.036107 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	1437	Shared Neighborhood Hits	24
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

RIMB1_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.044529 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	1376	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CYH1_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.013902 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

DHX16_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.028546 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	356	Shared Neighborhood Hits	17
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

NAF1_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.043356 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	852	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PININ_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.049990 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	753	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.049835 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	777	Shared Neighborhood Hits	25
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

CCD41_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.035753 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	1139	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

DPOLA_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.022896 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

AKA12_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.029947 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	825	Shared Neighborhood Hits	14
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DDX27_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.024464 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

KTN1_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.042780 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	1197	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

RBBP5_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.027156 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	372	Shared Neighborhood Hits	6
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

NAF1_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.040864 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	937	Shared Neighborhood Hits	25
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NASP_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.027717 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	709	Shared Neighborhood Hits	15
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SEPT1_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.008704 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).

SMC2_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.036706 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	1131	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

BAZ2B_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.026140 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	803	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CCD46_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.025419 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	1430	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CL025_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.042226 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

DICER_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.021316 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

PIBF1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.026052 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	1041	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

Hits sorted by NC score

ISY1_MOUSE
NC score	0.999962 (rank : 1)	θ value	4.00889e-141 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q69ZQ2, Q8VDX4, Q9D3E2	Gene names	Kiaa1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

ISY1_HUMAN
NC score	0.990131 (rank : 2)	θ value	7.07634e-138 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULR0, Q96IL2, Q9BT05	Gene names	KIAA1160
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor ISY1 homolog.

OPTN_HUMAN
NC score	0.077840 (rank : 3)	θ value	0.0961366 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	827	Shared Neighborhood Hits	26
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

SPRL1_MOUSE
NC score	0.062355 (rank : 4)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CDC37_HUMAN
NC score	0.059742 (rank : 5)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	506	Shared Neighborhood Hits	21
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CCD21_MOUSE
NC score	0.055835 (rank : 6)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

OPTN_MOUSE
NC score	0.053990 (rank : 7)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	1120	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CCD21_HUMAN
NC score	0.053598 (rank : 8)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	1228	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

PININ_HUMAN
NC score	0.049990 (rank : 9)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	753	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
NC score	0.049835 (rank : 10)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	777	Shared Neighborhood Hits	25
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

KTN1_MOUSE
NC score	0.045867 (rank : 11)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	1324	Shared Neighborhood Hits	27
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

RIMB1_MOUSE
NC score	0.044529 (rank : 12)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	1376	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NAF1_MOUSE
NC score	0.043356 (rank : 13)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	852	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

KTN1_HUMAN
NC score	0.042780 (rank : 14)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	1197	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CL025_HUMAN
NC score	0.042226 (rank : 15)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

CNTRB_MOUSE
NC score	0.041616 (rank : 16)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	1029	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NAF1_HUMAN
NC score	0.040864 (rank : 17)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	937	Shared Neighborhood Hits	25
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

SPTA2_HUMAN
NC score	0.039811 (rank : 18)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	888	Shared Neighborhood Hits	19
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SMC2_HUMAN
NC score	0.037276 (rank : 19)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	1405	Shared Neighborhood Hits	26
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
NC score	0.036706 (rank : 20)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	1131	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

GOGA3_MOUSE
NC score	0.036107 (rank : 21)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	1437	Shared Neighborhood Hits	24
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CCD41_HUMAN
NC score	0.035753 (rank : 22)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	1139	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

DDX27_MOUSE
NC score	0.035594 (rank : 23)	θ value	0.21417 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

AKA12_HUMAN
NC score	0.029947 (rank : 24)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	825	Shared Neighborhood Hits	14
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DHX16_HUMAN
NC score	0.028546 (rank : 25)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	356	Shared Neighborhood Hits	17
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

NASP_HUMAN
NC score	0.027717 (rank : 26)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	709	Shared Neighborhood Hits	15
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RBBP5_HUMAN
NC score	0.027156 (rank : 27)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	372	Shared Neighborhood Hits	6
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

BAZ2B_HUMAN
NC score	0.026140 (rank : 28)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	803	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PIBF1_HUMAN
NC score	0.026052 (rank : 29)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	1041	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CCD46_HUMAN
NC score	0.025419 (rank : 30)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	1430	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DDX27_HUMAN
NC score	0.024464 (rank : 31)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DPOLA_HUMAN
NC score	0.022896 (rank : 32)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DICER_MOUSE
NC score	0.021316 (rank : 33)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	140	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

CYH1_MOUSE
NC score	0.013902 (rank : 34)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

SEPT1_MOUSE
NC score	0.008704 (rank : 35)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P42209	Gene names	Sept1, Diff6, Pnutl3
Domain Architecture
Description	Septin-1 (Differentiation protein 6) (Diff6 protein).