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Network neighborhood for query Sequence : THAP4_HUMAN

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THAP4_HUMAN
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

THAP4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

THAP4_MOUSE
θ value	0 (rank : 2)	NC score	0.959469 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	37
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

THAP1_HUMAN
θ value	1.99529e-15 (rank : 3)	NC score	0.679490 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NVV9, Q53FQ1, Q6IA99	Gene names	THAP1
Domain Architecture
Description	THAP domain-containing protein 1.

THAP1_MOUSE
θ value	4.44505e-15 (rank : 4)	NC score	0.676378 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHW1	Gene names	Thap1
Domain Architecture
Description	THAP domain-containing protein 1.

THAP8_HUMAN
θ value	4.91457e-14 (rank : 5)	NC score	0.688881 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NA92, Q96M21	Gene names	THAP8
Domain Architecture
Description	THAP domain-containing protein 8.

THAP2_HUMAN
θ value	2.28291e-11 (rank : 6)	NC score	0.632348 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0W7	Gene names	THAP2
Domain Architecture
Description	THAP domain-containing protein 2.

THAP2_MOUSE
θ value	3.89403e-11 (rank : 7)	NC score	0.633473 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D305	Gene names	Thap2
Domain Architecture
Description	THAP domain-containing protein 2.

THAP3_HUMAN
θ value	1.63604e-09 (rank : 8)	NC score	0.603686 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WTV1, Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2, Q9Y3H3	Gene names	THAP3
Domain Architecture
Description	THAP domain-containing protein 3.

THAP3_MOUSE
θ value	8.11959e-09 (rank : 9)	NC score	0.599405 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJ25, Q8BII6	Gene names	Thap3
Domain Architecture
Description	THAP domain-containing protein 3.

THAP7_MOUSE
θ value	3.08544e-08 (rank : 10)	NC score	0.511568 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

THAP7_HUMAN
θ value	6.87365e-08 (rank : 11)	NC score	0.511814 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

THAP6_HUMAN
θ value	4.45536e-07 (rank : 12)	NC score	0.553244 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

P52K_HUMAN
θ value	9.29e-05 (rank : 13)	NC score	0.294654 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

P52K_MOUSE
θ value	9.29e-05 (rank : 14)	NC score	0.302253 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CUX1, Q80Y58	Gene names	Prkrir, Thap0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (THAP domain-containing protein 0).

CD2L5_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.020109 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	1011	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

RFIP1_MOUSE
θ value	0.00869519 (rank : 16)	NC score	0.065040 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TXND2_HUMAN
θ value	0.0431538 (rank : 17)	NC score	0.056871 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	793	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RRBP1_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.031720 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	1306	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CD2L5_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.017189 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	987	Shared Neighborhood Hits	15
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

NACAM_MOUSE
θ value	0.0961366 (rank : 20)	NC score	0.035962 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LZTS1_MOUSE
θ value	0.279714 (rank : 21)	NC score	0.054525 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	540	Shared Neighborhood Hits	18
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

ASCL1_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.051507 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

ASCL1_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.051591 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

AIM1_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.036028 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

IQEC3_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.027231 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

RC3H1_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.028150 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	433	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RAD50_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.022636 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	1366	Shared Neighborhood Hits	21
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SRRM2_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.036714 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ADDB_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.023447 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	574	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BCOR_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.017547 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	521	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CLAT_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.017040 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P28329, Q16488, Q9BQ23, Q9BQ35, Q9BQE1	Gene names	CHAT
Domain Architecture
Description	Choline O-acetyltransferase (EC 2.3.1.6) (CHOACTase) (Choline acetylase) (ChAT).

CACB3_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.020338 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CCD21_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.026225 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	1228	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

LIPB2_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.028808 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MN1_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.043554 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

SHE_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.022419 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

TCF20_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.026947 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	323	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CHIT1_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.013502 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

DESP_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.013735 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	1470	Shared Neighborhood Hits	21
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

KI21A_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.018967 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	1317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LAD1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.041339 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LIPA2_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.019926 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	1282	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MKL1_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.019560 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NUMA1_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.019263 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	1523	Shared Neighborhood Hits	23
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ROBO4_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.015833 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	364	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

SAS6_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.021972 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	791	Shared Neighborhood Hits	19
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SHB_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.021239 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

STAU1_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.020935 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

TIAM1_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.013912 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TOPK_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.011307 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	618	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

ATF6A_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.022218 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CAMKV_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.005873 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	1084	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

FYV1_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.014294 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

LIPA2_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.019816 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	1044	Shared Neighborhood Hits	18
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MLL4_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.019775 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	722	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

N4BP3_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.050677 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

PI5PA_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.024142 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	749	Shared Neighborhood Hits	14
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ROBO4_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.014927 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SWP70_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.023465 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	973	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.023182 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	1097	Shared Neighborhood Hits	17
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ASPX_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.043340 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

GOGB1_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.014292 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	2297	Shared Neighborhood Hits	27
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HNRPD_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.006350 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	Q14103, Q01858, Q14100, Q14101, Q14102	Gene names	HNRPD, AUF1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

MAGE1_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.018557 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	1389	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RPC5_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.018993 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

RUNX2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.020729 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.020379 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

STYK1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.003087 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	779	Shared Neighborhood Hits	7
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

ASCL3_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.027177 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

DAF1_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.007541 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	204	Shared Neighborhood Hits	3
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DMRT1_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.015426 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

EMIL2_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.012328 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	485	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

FOXD3_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.005081 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU5, Q9BYM2, Q9UDD1	Gene names	FOXD3
Domain Architecture
Description	Forkhead box protein D3 (HNF3/FH transcription factor genesis).

MBB1A_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.024040 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	665	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

N4BP3_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.031890 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C7U1, Q3TDC7, Q7TNR2, Q922W0, Q99J06	Gene names	N4bp3
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

NP1L3_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.026076 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

RNZ2_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.015610 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y81, Q99MF0, Q99MF1, Q9CTA2, Q9D1A8, Q9EPZ2	Gene names	Elac2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2).

SOX13_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.008281 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	495	Shared Neighborhood Hits	7
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

T22D4_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.015179 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

AFF4_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.024213 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	611	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BRWD1_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.005524 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	478	Shared Neighborhood Hits	6
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

EP15R_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.014622 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	1083	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

FANCM_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.009416 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FBX38_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.012593 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

FILA_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.020382 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	685	Shared Neighborhood Hits	15
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FREA_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.005827 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

INVS_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.004448 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	609	Shared Neighborhood Hits	12
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MAP1B_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.023998 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	903	Shared Neighborhood Hits	23
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SNRK_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.002879 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	855	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

SPAST_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.004643 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SREC_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.009660 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	5
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STRN3_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.005005 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

THA10_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.122311 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2Z0	Gene names	THAP10
Domain Architecture
Description	THAP domain-containing protein 10.

THA11_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.080294 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EK4, O94795	Gene names	THAP11
Domain Architecture
Description	THAP domain-containing protein 11.

THA11_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.068926 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJD0	Gene names	Thap11
Domain Architecture
Description	THAP domain-containing protein 11.

Hits sorted by NC score

THAP4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

THAP4_MOUSE
NC score	0.959469 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	37
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

THAP8_HUMAN
NC score	0.688881 (rank : 3)	θ value	4.91457e-14 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NA92, Q96M21	Gene names	THAP8
Domain Architecture
Description	THAP domain-containing protein 8.

THAP1_HUMAN
NC score	0.679490 (rank : 4)	θ value	1.99529e-15 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NVV9, Q53FQ1, Q6IA99	Gene names	THAP1
Domain Architecture
Description	THAP domain-containing protein 1.

THAP1_MOUSE
NC score	0.676378 (rank : 5)	θ value	4.44505e-15 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHW1	Gene names	Thap1
Domain Architecture
Description	THAP domain-containing protein 1.

THAP2_MOUSE
NC score	0.633473 (rank : 6)	θ value	3.89403e-11 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D305	Gene names	Thap2
Domain Architecture
Description	THAP domain-containing protein 2.

THAP2_HUMAN
NC score	0.632348 (rank : 7)	θ value	2.28291e-11 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0W7	Gene names	THAP2
Domain Architecture
Description	THAP domain-containing protein 2.

THAP3_HUMAN
NC score	0.603686 (rank : 8)	θ value	1.63604e-09 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WTV1, Q569K1, Q5TH66, Q5TH67, Q8N8T6, Q9BSC7, Q9Y3H2, Q9Y3H3	Gene names	THAP3
Domain Architecture
Description	THAP domain-containing protein 3.

THAP3_MOUSE
NC score	0.599405 (rank : 9)	θ value	8.11959e-09 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJ25, Q8BII6	Gene names	Thap3
Domain Architecture
Description	THAP domain-containing protein 3.

THAP6_HUMAN
NC score	0.553244 (rank : 10)	θ value	4.45536e-07 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

THAP7_HUMAN
NC score	0.511814 (rank : 11)	θ value	6.87365e-08 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

THAP7_MOUSE
NC score	0.511568 (rank : 12)	θ value	3.08544e-08 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

P52K_MOUSE
NC score	0.302253 (rank : 13)	θ value	9.29e-05 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CUX1, Q80Y58	Gene names	Prkrir, Thap0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (THAP domain-containing protein 0).

P52K_HUMAN
NC score	0.294654 (rank : 14)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

THA10_HUMAN
NC score	0.122311 (rank : 15)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2Z0	Gene names	THAP10
Domain Architecture
Description	THAP domain-containing protein 10.

THA11_HUMAN
NC score	0.080294 (rank : 16)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q96EK4, O94795	Gene names	THAP11
Domain Architecture
Description	THAP domain-containing protein 11.

THA11_MOUSE
NC score	0.068926 (rank : 17)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJD0	Gene names	Thap11
Domain Architecture
Description	THAP domain-containing protein 11.

RFIP1_MOUSE
NC score	0.065040 (rank : 18)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TXND2_HUMAN
NC score	0.056871 (rank : 19)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	793	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

LZTS1_MOUSE
NC score	0.054525 (rank : 20)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	540	Shared Neighborhood Hits	18
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

ASCL1_MOUSE
NC score	0.051591 (rank : 21)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

ASCL1_HUMAN
NC score	0.051507 (rank : 22)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

N4BP3_HUMAN
NC score	0.050677 (rank : 23)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

MN1_HUMAN
NC score	0.043554 (rank : 24)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

ASPX_MOUSE
NC score	0.043340 (rank : 25)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

LAD1_HUMAN
NC score	0.041339 (rank : 26)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	441	Shared Neighborhood Hits	13
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

SRRM2_MOUSE
NC score	0.036714 (rank : 27)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AIM1_HUMAN
NC score	0.036028 (rank : 28)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

NACAM_MOUSE
NC score	0.035962 (rank : 29)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

N4BP3_MOUSE
NC score	0.031890 (rank : 30)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	179	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C7U1, Q3TDC7, Q7TNR2, Q922W0, Q99J06	Gene names	N4bp3
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

RRBP1_HUMAN
NC score	0.031720 (rank : 31)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	1306	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

LIPB2_MOUSE
NC score	0.028808 (rank : 32)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

RC3H1_HUMAN
NC score	0.028150 (rank : 33)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	433	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

IQEC3_MOUSE
NC score	0.027231 (rank : 34)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

ASCL3_HUMAN
NC score	0.027177 (rank : 35)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

TCF20_HUMAN
NC score	0.026947 (rank : 36)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	323	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CCD21_HUMAN
NC score	0.026225 (rank : 37)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	1228	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

NP1L3_HUMAN
NC score	0.026076 (rank : 38)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

AFF4_HUMAN
NC score	0.024213 (rank : 39)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	611	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

PI5PA_HUMAN
NC score	0.024142 (rank : 40)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	749	Shared Neighborhood Hits	14
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MBB1A_HUMAN
NC score	0.024040 (rank : 41)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	665	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MAP1B_HUMAN
NC score	0.023998 (rank : 42)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	903	Shared Neighborhood Hits	23
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SWP70_HUMAN
NC score	0.023465 (rank : 43)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	973	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ADDB_MOUSE
NC score	0.023447 (rank : 44)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	574	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

SWP70_MOUSE
NC score	0.023182 (rank : 45)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	1097	Shared Neighborhood Hits	17
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RAD50_MOUSE
NC score	0.022636 (rank : 46)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	1366	Shared Neighborhood Hits	21
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SHE_MOUSE
NC score	0.022419 (rank : 47)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BSD5, Q3TZT0	Gene names	She
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

ATF6A_HUMAN
NC score	0.022218 (rank : 48)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

SAS6_HUMAN
NC score	0.021972 (rank : 49)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	791	Shared Neighborhood Hits	19
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SHB_HUMAN
NC score	0.021239 (rank : 50)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	Q15464, Q504U5, Q5VUM8	Gene names	SHB
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein B.

STAU1_MOUSE
NC score	0.020935 (rank : 51)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

RUNX2_HUMAN
NC score	0.020729 (rank : 52)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

FILA_HUMAN
NC score	0.020382 (rank : 53)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	685	Shared Neighborhood Hits	15
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RUNX2_MOUSE
NC score	0.020379 (rank : 54)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

CACB3_MOUSE
NC score	0.020338 (rank : 55)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

CD2L5_MOUSE
NC score	0.020109 (rank : 56)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	1011	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

LIPA2_MOUSE
NC score	0.019926 (rank : 57)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	1282	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LIPA2_HUMAN
NC score	0.019816 (rank : 58)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	1044	Shared Neighborhood Hits	18
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MLL4_HUMAN
NC score	0.019775 (rank : 59)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	722	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MKL1_MOUSE
NC score	0.019560 (rank : 60)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NUMA1_HUMAN
NC score	0.019263 (rank : 61)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	1523	Shared Neighborhood Hits	23
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RPC5_MOUSE
NC score	0.018993 (rank : 62)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

KI21A_MOUSE
NC score	0.018967 (rank : 63)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	1317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MAGE1_HUMAN
NC score	0.018557 (rank : 64)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	1389	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BCOR_MOUSE
NC score	0.017547 (rank : 65)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	521	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CD2L5_HUMAN
NC score	0.017189 (rank : 66)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	987	Shared Neighborhood Hits	15
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CLAT_HUMAN
NC score	0.017040 (rank : 67)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P28329, Q16488, Q9BQ23, Q9BQ35, Q9BQE1	Gene names	CHAT
Domain Architecture
Description	Choline O-acetyltransferase (EC 2.3.1.6) (CHOACTase) (Choline acetylase) (ChAT).

ROBO4_HUMAN
NC score	0.015833 (rank : 68)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	364	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

RNZ2_MOUSE
NC score	0.015610 (rank : 69)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y81, Q99MF0, Q99MF1, Q9CTA2, Q9D1A8, Q9EPZ2	Gene names	Elac2
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (Ribonuclease Z 2) (RNase Z 2) (tRNase Z 2) (tRNA 3 endonuclease 2) (ElaC homolog protein 2).

DMRT1_MOUSE
NC score	0.015426 (rank : 70)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

T22D4_HUMAN
NC score	0.015179 (rank : 71)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ROBO4_MOUSE
NC score	0.014927 (rank : 72)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

EP15R_HUMAN
NC score	0.014622 (rank : 73)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	1083	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

FYV1_MOUSE
NC score	0.014294 (rank : 74)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GOGB1_HUMAN
NC score	0.014292 (rank : 75)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	2297	Shared Neighborhood Hits	27
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TIAM1_MOUSE
NC score	0.013912 (rank : 76)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

DESP_HUMAN
NC score	0.013735 (rank : 77)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	1470	Shared Neighborhood Hits	21
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CHIT1_MOUSE
NC score	0.013502 (rank : 78)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7Q1, Q6QJD2	Gene names	Chit1
Domain Architecture
Description	Chitotriosidase-1 precursor (EC 3.2.1.14) (Chitinase-1).

FBX38_MOUSE
NC score	0.012593 (rank : 79)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

EMIL2_MOUSE
NC score	0.012328 (rank : 80)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	485	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K482	Gene names	Emilin2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Basilin).

TOPK_MOUSE
NC score	0.011307 (rank : 81)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	618	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

SREC_HUMAN
NC score	0.009660 (rank : 82)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	5
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FANCM_HUMAN
NC score	0.009416 (rank : 83)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

SOX13_MOUSE
NC score	0.008281 (rank : 84)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	495	Shared Neighborhood Hits	7
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

DAF1_MOUSE
NC score	0.007541 (rank : 85)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	204	Shared Neighborhood Hits	3
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

HNRPD_HUMAN
NC score	0.006350 (rank : 86)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	Q14103, Q01858, Q14100, Q14101, Q14102	Gene names	HNRPD, AUF1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1).

CAMKV_HUMAN
NC score	0.005873 (rank : 87)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	1084	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

FREA_HUMAN
NC score	0.005827 (rank : 88)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

BRWD1_MOUSE
NC score	0.005524 (rank : 89)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	478	Shared Neighborhood Hits	6
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

FOXD3_HUMAN
NC score	0.005081 (rank : 90)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU5, Q9BYM2, Q9UDD1	Gene names	FOXD3
Domain Architecture
Description	Forkhead box protein D3 (HNF3/FH transcription factor genesis).

STRN3_HUMAN
NC score	0.005005 (rank : 91)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q13033, Q9NRA5	Gene names	STRN3, GS2NA, SG2NA
Domain Architecture
Description	Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen).

SPAST_MOUSE
NC score	0.004643 (rank : 92)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

INVS_MOUSE
NC score	0.004448 (rank : 93)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	609	Shared Neighborhood Hits	12
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

STYK1_MOUSE
NC score	0.003087 (rank : 94)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	779	Shared Neighborhood Hits	7
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SNRK_HUMAN
NC score	0.002879 (rank : 95)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	855	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).