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Network neighborhood for query Sequence : SYFA_HUMAN

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SYFA_HUMAN
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYFA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).

SYFM_MOUSE
θ value	2.79066e-09 (rank : 2)	NC score	0.435012 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q99M01, Q3TBZ7, Q9CYY0	Gene names	Fars2, Fars1
Domain Architecture	No domain graphic available
Description	Phenylalanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.20) (Phenylalanine--tRNA ligase) (PheRS).

SYFM_HUMAN
θ value	1.80886e-08 (rank : 3)	NC score	0.425833 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O95363, Q53F66, Q5TCS3, Q6FG29, Q9NPY7, Q9P062	Gene names	FARS2, FARS1
Domain Architecture	No domain graphic available
Description	Phenylalanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.20) (Phenylalanine--tRNA ligase) (PheRS).

CKAP4_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.032687 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

KIF14_HUMAN
θ value	3.0926 (rank : 5)	NC score	0.013751 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	732	Shared Neighborhood Hits	5
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

LAMA3_MOUSE
θ value	3.0926 (rank : 6)	NC score	0.013652 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	859	Shared Neighborhood Hits	5
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

GT2D1_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.025149 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

MAST3_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.003498 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1128	Shared Neighborhood Hits	3
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MYH7_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.007020 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	1559	Shared Neighborhood Hits	7
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NFH_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.006361 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	2247	Shared Neighborhood Hits	7
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CSF1_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.018199 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

RIMS1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.011373 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	437	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SMC2_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.011015 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	1131	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

Hits sorted by NC score

SYFA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).

SYFM_MOUSE
NC score	0.435012 (rank : 2)	θ value	2.79066e-09 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q99M01, Q3TBZ7, Q9CYY0	Gene names	Fars2, Fars1
Domain Architecture	No domain graphic available
Description	Phenylalanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.20) (Phenylalanine--tRNA ligase) (PheRS).

SYFM_HUMAN
NC score	0.425833 (rank : 3)	θ value	1.80886e-08 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O95363, Q53F66, Q5TCS3, Q6FG29, Q9NPY7, Q9P062	Gene names	FARS2, FARS1
Domain Architecture	No domain graphic available
Description	Phenylalanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.20) (Phenylalanine--tRNA ligase) (PheRS).

CKAP4_HUMAN
NC score	0.032687 (rank : 4)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

GT2D1_MOUSE
NC score	0.025149 (rank : 5)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

CSF1_HUMAN
NC score	0.018199 (rank : 6)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

KIF14_HUMAN
NC score	0.013751 (rank : 7)	θ value	3.0926 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	732	Shared Neighborhood Hits	5
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

LAMA3_MOUSE
NC score	0.013652 (rank : 8)	θ value	3.0926 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	859	Shared Neighborhood Hits	5
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

RIMS1_HUMAN
NC score	0.011373 (rank : 9)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	437	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SMC2_MOUSE
NC score	0.011015 (rank : 10)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1131	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MYH7_HUMAN
NC score	0.007020 (rank : 11)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	1559	Shared Neighborhood Hits	7
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NFH_MOUSE
NC score	0.006361 (rank : 12)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	2247	Shared Neighborhood Hits	7
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAST3_HUMAN
NC score	0.003498 (rank : 13)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	1128	Shared Neighborhood Hits	3
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).