Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : DEDD2_MOUSE

For an explanation of this page, click here

DEDD2_MOUSE
SwissProt Accessions	Q8QZV0, Q569Y9, Q8JZV1	Gene names	Dedd2, Flame3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DEDD2_MOUSE
θ value	7.10925e-122 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8QZV0, Q569Y9, Q8JZV1	Gene names	Dedd2, Flame3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

DEDD2_HUMAN
θ value	7.37397e-111 (rank : 2)	NC score	0.993516 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXF8, Q8NBR2, Q8NES1, Q8TAA8, Q96D35	Gene names	DEDD2, FLAME3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

DEDD_HUMAN
θ value	1.11475e-66 (rank : 3)	NC score	0.948751 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

DEDD_MOUSE
θ value	2.10232e-65 (rank : 4)	NC score	0.950197 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1L3, Q7TQH8, Q9R227	Gene names	Dedd
Domain Architecture
Description	Death effector domain-containing protein (DEDPro1).

RBBP6_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.029998 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	1135	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RPTN_MOUSE
θ value	0.47712 (rank : 6)	NC score	0.033946 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

PCX3_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.035999 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

ANK2_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.010857 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1615	Shared Neighborhood Hits	9
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CASP8_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.035978 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81	Gene names	CASP8, MCH5
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

CASPA_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.022665 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7	Gene names	CASP10, MCH4
Domain Architecture
Description	Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12].

NPBL_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.022505 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1041	Shared Neighborhood Hits	7
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

T53G5_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.036664 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2B4	Gene names	TP53TG5, C20orf10
Domain Architecture	No domain graphic available
Description	TP53-target gene 5 protein (TP53-inducible gene 5 protein).

NIPBL_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.019869 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	1311	Shared Neighborhood Hits	7
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RIMS1_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.010254 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	437	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

Hits sorted by NC score

DEDD2_MOUSE
NC score	0.999962 (rank : 1)	θ value	7.10925e-122 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8QZV0, Q569Y9, Q8JZV1	Gene names	Dedd2, Flame3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

DEDD2_HUMAN
NC score	0.993516 (rank : 2)	θ value	7.37397e-111 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXF8, Q8NBR2, Q8NES1, Q8TAA8, Q96D35	Gene names	DEDD2, FLAME3
Domain Architecture	No domain graphic available
Description	DNA-binding death effector domain-containing protein 2 (FADD-like anti-apoptotic molecule 3) (DED-containing protein FLAME-3).

DEDD_MOUSE
NC score	0.950197 (rank : 3)	θ value	2.10232e-65 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1L3, Q7TQH8, Q9R227	Gene names	Dedd
Domain Architecture
Description	Death effector domain-containing protein (DEDPro1).

DEDD_HUMAN
NC score	0.948751 (rank : 4)	θ value	1.11475e-66 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

T53G5_HUMAN
NC score	0.036664 (rank : 5)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2B4	Gene names	TP53TG5, C20orf10
Domain Architecture	No domain graphic available
Description	TP53-target gene 5 protein (TP53-inducible gene 5 protein).

PCX3_MOUSE
NC score	0.035999 (rank : 6)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

CASP8_HUMAN
NC score	0.035978 (rank : 7)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q14790, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81	Gene names	CASP8, MCH5
Domain Architecture
Description	Caspase-8 precursor (EC 3.4.22.-) (CASP-8) (ICE-like apoptotic protease 5) (MORT1-associated CED-3 homolog) (MACH) (FADD-homologous ICE/CED-3-like protease) (FADD-like ICE) (FLICE) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) [Contains: Caspase-8 subunit p18; Caspase-8 subunit p10].

RPTN_MOUSE
NC score	0.033946 (rank : 8)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RBBP6_HUMAN
NC score	0.029998 (rank : 9)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	1135	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CASPA_HUMAN
NC score	0.022665 (rank : 10)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q92851, Q8WYQ8, Q99845, Q9Y2U6, Q9Y2U7	Gene names	CASP10, MCH4
Domain Architecture
Description	Caspase-10 precursor (EC 3.4.22.-) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12].

NPBL_MOUSE
NC score	0.022505 (rank : 11)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1041	Shared Neighborhood Hits	7
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.019869 (rank : 12)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1311	Shared Neighborhood Hits	7
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ANK2_HUMAN
NC score	0.010857 (rank : 13)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1615	Shared Neighborhood Hits	9
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RIMS1_HUMAN
NC score	0.010254 (rank : 14)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	437	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).