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Network neighborhood for query Sequence : IFRD1_HUMAN

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IFRD1_HUMAN
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IFRD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).

IFRD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999072 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P19182, P21835, P70228	Gene names	Ifrd1, Tis7
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein).

IFRD2_HUMAN
θ value	9.94316e-116 (rank : 3)	NC score	0.981532 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q12894	Gene names	IFRD2
Domain Architecture
Description	Interferon-related developmental regulator 2 (SKMC15 protein).

MSLN_MOUSE
θ value	0.47712 (rank : 4)	NC score	0.071775 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q61468	Gene names	Msln, Mes, Mpf
Domain Architecture	No domain graphic available
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

GDE1_MOUSE
θ value	4.03905 (rank : 5)	NC score	0.029758 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL56, Q3UBU4	Gene names	Gde1, Mir16
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase 1 (EC 3.1.4.44) (Membrane interacting protein of RGS16).

ITSN2_HUMAN
θ value	4.03905 (rank : 6)	NC score	0.008990 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	1173	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
θ value	5.27518 (rank : 7)	NC score	0.008101 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	1371	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SPB6_MOUSE
θ value	6.88961 (rank : 8)	NC score	0.008172 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q60854	Gene names	Serpinb6, Serpinb6a, Spi3
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Protease inhibitor 6) (PI- 6).

WNK3_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.001984 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	948	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

TAF6_HUMAN
θ value	8.99809 (rank : 10)	NC score	0.017637 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

Hits sorted by NC score

IFRD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O00458, O75234, Q5U013, Q9BVE4	Gene names	IFRD1
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4).

IFRD1_MOUSE
NC score	0.999072 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P19182, P21835, P70228	Gene names	Ifrd1, Tis7
Domain Architecture
Description	Interferon-related developmental regulator 1 (Nerve growth factor- inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein).

IFRD2_HUMAN
NC score	0.981532 (rank : 3)	θ value	9.94316e-116 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q12894	Gene names	IFRD2
Domain Architecture
Description	Interferon-related developmental regulator 2 (SKMC15 protein).

MSLN_MOUSE
NC score	0.071775 (rank : 4)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q61468	Gene names	Msln, Mes, Mpf
Domain Architecture	No domain graphic available
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

GDE1_MOUSE
NC score	0.029758 (rank : 5)	θ value	4.03905 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL56, Q3UBU4	Gene names	Gde1, Mir16
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase 1 (EC 3.1.4.44) (Membrane interacting protein of RGS16).

TAF6_HUMAN
NC score	0.017637 (rank : 6)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

ITSN2_HUMAN
NC score	0.008990 (rank : 7)	θ value	4.03905 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	1173	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SPB6_MOUSE
NC score	0.008172 (rank : 8)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q60854	Gene names	Serpinb6, Serpinb6a, Spi3
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Protease inhibitor 6) (PI- 6).

ITSN2_MOUSE
NC score	0.008101 (rank : 9)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	1371	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

WNK3_HUMAN
NC score	0.001984 (rank : 10)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	948	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).