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Network neighborhood for query Sequence : IF37_MOUSE

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IF37_MOUSE
SwissProt Accessions	O70194	Gene names	Eif3s7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IF37_HUMAN
θ value	0 (rank : 1)	NC score	0.993368 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	O15371, Q5M9Q6	Gene names	EIF3S7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

IF37_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	O70194	Gene names	Eif3s7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

CD2L1_HUMAN
θ value	0.0330416 (rank : 3)	NC score	0.025619 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	1467	Shared Neighborhood Hits	19
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

RBM25_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.058972 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ZC313_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.079912 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	772	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ITSN1_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.040021 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	1757	Shared Neighborhood Hits	36
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ZRF1_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.063029 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

IF3A_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.062911 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	875	Shared Neighborhood Hits	29
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

CLK4_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.021270 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAZ1	Gene names	CLK4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

ITSN1_MOUSE
θ value	1.06291 (rank : 10)	NC score	0.039423 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	1669	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PCNT_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.033710 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	1207	Shared Neighborhood Hits	29
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

TOP1_MOUSE
θ value	1.06291 (rank : 12)	NC score	0.052809 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	213	Shared Neighborhood Hits	5
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

U2AFM_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.045997 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CD2L1_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.020436 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	1463	Shared Neighborhood Hits	18
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

HRX_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.027189 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	825	Shared Neighborhood Hits	11
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IF3A_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.056519 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	871	Shared Neighborhood Hits	28
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

DDX23_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.014701 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	486	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

ENAH_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.026679 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	784	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

PCY1A_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.045784 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P49586, Q542W4	Gene names	Pcyt1a, Ctpct, Pcyt1
Domain Architecture
Description	Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (Phosphorylcholine transferase A) (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT A) (CCT-alpha).

BAZ2B_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.027054 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	803	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

FOXP2_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.017154 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

TRHY_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.020827 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	1385	Shared Neighborhood Hits	18
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CD2L2_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.020494 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	1439	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

FA50A_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.031976 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

ITSN2_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.035658 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	1371	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

M4K4_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.013086 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	1589	Shared Neighborhood Hits	22
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

RADI_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.013939 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	741	Shared Neighborhood Hits	13
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

DHX16_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.018535 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

GNL3_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.028378 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

ITSN2_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.030808 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1173	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

M4K4_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.013091 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	1560	Shared Neighborhood Hits	23
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NFM_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.013375 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	1159	Shared Neighborhood Hits	25
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PCY1A_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.037338 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P49585	Gene names	PCYT1A, CTPCT, PCYT1
Domain Architecture
Description	Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (Phosphorylcholine transferase A) (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT A) (CCT-alpha).

CLK4_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.015067 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	759	Shared Neighborhood Hits	10
SwissProt Accessions	O35493, O35721, Q8CEU9, Q99LU6	Gene names	Clk4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

INCE_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.024361 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	978	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

NKTR_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.015266 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	658	Shared Neighborhood Hits	20
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

5HT2C_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.003642 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	876	Shared Neighborhood Hits	3
SwissProt Accessions	P34968	Gene names	Htr2c, 5ht1c, Htr1c
Domain Architecture
Description	5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5- HT2C) (5-HTR2C) (5HT-1C).

CA065_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.030328 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	469	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CCD50_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.033225 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

FOXP2_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.014078 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	366	Shared Neighborhood Hits	8
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

HOOK2_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.022683 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	736	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

INCE_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.024468 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	903	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

NFH_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.009281 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	1242	Shared Neighborhood Hits	20
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SFR12_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.015863 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	486	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TOP1_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.033417 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

Hits sorted by NC score

IF37_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	O70194	Gene names	Eif3s7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

IF37_HUMAN
NC score	0.993368 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	O15371, Q5M9Q6	Gene names	EIF3S7
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta) (eIF3 p66) (eIF3d).

ZC313_HUMAN
NC score	0.079912 (rank : 3)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	772	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZRF1_MOUSE
NC score	0.063029 (rank : 4)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	P54103	Gene names	Zrf1, Dnajc2
Domain Architecture
Description	Zuotin-related factor 1.

IF3A_HUMAN
NC score	0.062911 (rank : 5)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	875	Shared Neighborhood Hits	29
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

RBM25_HUMAN
NC score	0.058972 (rank : 6)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

IF3A_MOUSE
NC score	0.056519 (rank : 7)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	871	Shared Neighborhood Hits	28
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

TOP1_MOUSE
NC score	0.052809 (rank : 8)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	213	Shared Neighborhood Hits	5
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

U2AFM_HUMAN
NC score	0.045997 (rank : 9)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

PCY1A_MOUSE
NC score	0.045784 (rank : 10)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P49586, Q542W4	Gene names	Pcyt1a, Ctpct, Pcyt1
Domain Architecture
Description	Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (Phosphorylcholine transferase A) (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT A) (CCT-alpha).

ITSN1_HUMAN
NC score	0.040021 (rank : 11)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	1757	Shared Neighborhood Hits	36
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.039423 (rank : 12)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	1669	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PCY1A_HUMAN
NC score	0.037338 (rank : 13)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P49585	Gene names	PCYT1A, CTPCT, PCYT1
Domain Architecture
Description	Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (Phosphorylcholine transferase A) (CTP:phosphocholine cytidylyltransferase A) (CT A) (CCT A) (CCT-alpha).

ITSN2_MOUSE
NC score	0.035658 (rank : 14)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	1371	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PCNT_MOUSE
NC score	0.033710 (rank : 15)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	1207	Shared Neighborhood Hits	29
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

TOP1_HUMAN
NC score	0.033417 (rank : 16)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

CCD50_MOUSE
NC score	0.033225 (rank : 17)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

FA50A_HUMAN
NC score	0.031976 (rank : 18)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	264	Shared Neighborhood Hits	5
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

ITSN2_HUMAN
NC score	0.030808 (rank : 19)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	1173	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CA065_HUMAN
NC score	0.030328 (rank : 20)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	469	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

GNL3_MOUSE
NC score	0.028378 (rank : 21)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

HRX_HUMAN
NC score	0.027189 (rank : 22)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	825	Shared Neighborhood Hits	11
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

BAZ2B_HUMAN
NC score	0.027054 (rank : 23)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	803	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

ENAH_HUMAN
NC score	0.026679 (rank : 24)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	784	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CD2L1_HUMAN
NC score	0.025619 (rank : 25)	θ value	0.0330416 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	1467	Shared Neighborhood Hits	19
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

INCE_MOUSE
NC score	0.024468 (rank : 26)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	903	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INCE_HUMAN
NC score	0.024361 (rank : 27)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	978	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

HOOK2_MOUSE
NC score	0.022683 (rank : 28)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	736	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

CLK4_HUMAN
NC score	0.021270 (rank : 29)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAZ1	Gene names	CLK4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

TRHY_HUMAN
NC score	0.020827 (rank : 30)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	1385	Shared Neighborhood Hits	18
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CD2L2_HUMAN
NC score	0.020494 (rank : 31)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	1439	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CD2L1_MOUSE
NC score	0.020436 (rank : 32)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	1463	Shared Neighborhood Hits	18
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DHX16_HUMAN
NC score	0.018535 (rank : 33)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

FOXP2_HUMAN
NC score	0.017154 (rank : 34)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

SFR12_MOUSE
NC score	0.015863 (rank : 35)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	486	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

NKTR_HUMAN
NC score	0.015266 (rank : 36)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	658	Shared Neighborhood Hits	20
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CLK4_MOUSE
NC score	0.015067 (rank : 37)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	759	Shared Neighborhood Hits	10
SwissProt Accessions	O35493, O35721, Q8CEU9, Q99LU6	Gene names	Clk4
Domain Architecture
Description	Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4).

DDX23_HUMAN
NC score	0.014701 (rank : 38)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	486	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

FOXP2_MOUSE
NC score	0.014078 (rank : 39)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	366	Shared Neighborhood Hits	8
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

RADI_HUMAN
NC score	0.013939 (rank : 40)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	741	Shared Neighborhood Hits	13
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

NFM_MOUSE
NC score	0.013375 (rank : 41)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	1159	Shared Neighborhood Hits	25
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

M4K4_MOUSE
NC score	0.013091 (rank : 42)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	1560	Shared Neighborhood Hits	23
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.013086 (rank : 43)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	1589	Shared Neighborhood Hits	22
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NFH_HUMAN
NC score	0.009281 (rank : 44)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	1242	Shared Neighborhood Hits	20
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

5HT2C_MOUSE
NC score	0.003642 (rank : 45)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	876	Shared Neighborhood Hits	3
SwissProt Accessions	P34968	Gene names	Htr2c, 5ht1c, Htr1c
Domain Architecture
Description	5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5- HT2C) (5-HTR2C) (5HT-1C).